Mobile learning (m-learning) adoption has increased and shall be demonstrated superior performance by implementing related computing paradigms, such as IoT, edge, mobile edge, fog, AI, and 5G. Mobile cloud architectures (MCAs) enable m-learning with several benefits and face limitations while executing real-time applications. This study investigates the state-of-the-art m-learning architectures, determines a layered m-learning-MCA obtaining numerous benefits of related computing paradigms, and expands m-learning functional structure. It evaluates m-learning performance across the four physical layer’s MCAs—distance cloud, cloudlet, operator-centric cloud, ad hoc cloud, and emerging computing architectures. Surprisingly, only distance-cloud MCA is adopted for developing m-learning systems by ignoring the other three. Performance evaluation shows m-learning gets terrific benefits and users QoE in related computing paradigms. Mobile edge computing offers ultralow latency, whereas the current architecture improves task execution time (1.87, 2.01, 2.63, and 3.97) for the resource-intensive application (i.e., 4.2 MB). Fog using AI algorithms is exceptional for more complex learning objects, IoT is superior for intelligent learning tools, and 5G ultrawideband services are more significant for intelligent video analytics. These findings help learners, educators, and institutions adopt an appropriate model for achieving their academic objectives across educational disciplines. The presented approach enables future research to design innovative architectures considering resource-intensive m-learning application execution requirements, such as video content analytics and virtual reality learning models.