Abstract Considering the continuous development of sustainable development, energy saving, and emission reduction concepts, it is very important to reduce concrete’s cement content in order to improve its environmental impact. Using a reactive admixture to replace part of the cement in ultra-high-performance concrete (UHPC) can effectively improve the overall performance of the concrete and reduce carbon dioxide emissions, which is an important aspect of environmental protection. Here, industrial waste residue (fly ash and slag), sea sand (SS), and manufactured sand (MS) were used to produce UHPC under standard curing conditions to reduce the material cost and make it more environmentally friendly and sustainable. The effects of water–binder ratio, contents of cementitious materials, types of sands, and content of steel fibers on the mechanical performance of UHPC under standard curing were investigated experimentally. In addition, evaluations of the impermeability, chloride, and freeze-thaw resistance of various UHPCs produced were conducted by investigating the effects of various factors on the depth under hydraulic pressure and electric flux of UHPC, as well as the mass loss, relative dynamic modulus of elasticity, flexural strength, and compressive strength of UHPC specimens after freeze-thaw cycles. The obtained experimental results show that the SS-UHPC and MS-UHPC prepared by standard curing exhibit high strength, excellent impermeability, and chloride resistance. The frost-resistant grade of all groups of UHPCs prepared by standard curing was greater than F500 and had excellent freeze–thaw resistance, including those produced with local tap water or artificial seawater. The investigation presented in this paper could contribute to the production of new low-cost and environmentally friendly UHPCs and accelerate the application of UHPC in engineering structures.