A six-axis robot is a type of robotic manipulator with six degrees of freedom (DOF) that enable it to move and rotate in six different directions. Because of its flexibility and high-precision operation, it is widely used in industrial production lines, semiconductor manufacturing, medical surgery and other fields. In the future, with the development of artificial intelligence, sensor technology and other fields, six-axis robots will achieve more intelligent and autonomous operation, and will also be more widely used in industry, medical treatment, service and other fields. In this paper, the important applications of six-axis robots in industry and other fields are introduced by introducing the relevant applications of artificial intelligence and robots. Then the DH representation method and inverse solution method are introduced, and a six-axis robot is modeled and the relevant data are calculated in MATLAB software using the DH representation method and inverse solution method. Finally, the trajectory of the robot gripper was simulated and the simulation results were obtained, which preliminarily verified the feasibility and reliability of the six-axis robot grasping objects.