Ontology enhances semantic interoperability through integrating health data from heterogeneous sources and sharing information in a meaningful way. In the field of smart health services, semantic interoperability means the exchange and interpretation of data without ambiguity and uncertainty. However, existing classical ontologies are not able to represent vague and uncertain knowledge, especially in contexts of mental health disorders which are associated with varying degrees of uncertainty and inaccuracy of diagnosis, and in this case, the treatment is a complex and common mental process necessitating to share information accurately and unambiguously. Type-2 fuzzy set theory can offer a fruitful solution in order to control uncertainty or express ambiguous concepts in a dynamic and complex environment such as healthcare systems. Herein, a semantic framework for healthcare, and also monitoring mental health disorders using type-2 fuzzy set theory based on the Internet of Thing (IoT) is suggested, in which all depression-related concepts are semantically annotated to share detailed information with the treatment staff. This framework not only paved the way to increasing the accuracy of medical diagnosis and decision-making but also provides the possibility of inference and semantic reasoning using the languages of SPARQL query and DL query.