In this work, a novel mathematical model of thermoelastic, homogenous, isotropic, and infinite medium with a spherical cavity has been constructed. Under the hyperbolic two-temperature Green-Naghdi theory of thermoelasticity type-I and type-III with fractional-order strain, the governing equations have been established. The bounding surface of the cavity has been thermally loaded by a ramp-type heat and is connected to a rigid foundation which prevents volumetric strain. Different values of the fractional-order and two-temperature parameters have shown numerical results for the dynamical and conductive temperature increment, strain, displacement, and average of principal stresses, which are graphically applicable to all the functions studied. The fractional-order parameter has significant effects on stress and strain distributions, while it has a limited effect on the dynamical and conductive temperatures increment. The hyperbolic two-temperature parameter has significant effects on all studied functions based on Green-Naghdi models of type-1 and type-II. Moreover, the ramp-time heat parameter has a significant impact on all the studied functions under all the studied models of thermoelasticity.