This study investigates the Dynamic Coupling between Land Use Economic Efficiency (LUEE) and Urban Ecological Resilience (UER) in the Yellow River Basin (YRB). This exploration is pivotal for elucidating the interaction mechanisms between economic growth and ecological governance. Furthermore, understanding this relationship is essential for fostering high-quality, sustainable urban development in the YRB. Utilizing panel data from 56 cities spanning 2003 to 2020, this study employed the coupling coordination degree (CCD) model, spatial correlation analysis, Kernel density estimation, convergence model, and Geodetector to systematically analyze the spatio-temporal distribution, dynamic trend, and determinants of the CCD between LUEE and UER in the YRB. The findings indicate that: (1) A general upward trend in both LUEE and UER, accompanied by a steady improvement in their CCD. (2) Significant spatial disparities in their CCD, with higher levels in the lower reaches. (3) Marked positive spatial autocorrelation, predominantly characterized by clusters where high (low) values are surrounded by high (low) values. (4) Regarding the impact of individual factors, government fiscal budget expenditure demonstrates the most robust explanatory power for the CCD within the YRB. Concerning the effects of two-factor interactions, the interplay between industrial structure upgrading and government fiscal budget expenditure emerges as the most significant determinant in influencing the CCD between LUEE and UER. This study enhances our comprehensive understanding of the interplay between economic and ecological systems. It offers scientific insights and strategic direction for harmonizing ecological governance with urban economic growth at both the regional and global scales.