On the February 11, 2020, the World Health Organization (WHO) gave the name of COVID-19 to a new coronavirus that had not been previously identified in humans. Although the virus began in Wuhan, China, in December 2019, within weeks it spread worldwide to almost every continent. This virus is part of an ongoing pandemic that causes severe acute respiratory symptoms. Many countries went into complete lockdown in order to contain the proliferation of this virus. This lockdown due to the widespread pandemic experienced for the first time in a century worldwide, triggered concern, fear, anxiety and stress, all of which are expected and normal reactions to the altering and uncertain state that people found themselves undergoing. Some of the main concerns facing many was how to manage and react to the stressful situation of coronavirus, how to remain confined at home, and how to handle the unfolding narrative so rapidly unfolding in the lives within communities-lives that had been “turned upside down” in a matter of a few weeks. This research looks at the state of mind of citizens in four continents: Africa, Australia, Europe, and India, of the world during lockdown. It also explores whether a novel illness such as COVID-19 can cause mental health issues, widespread fear, and anxiety, among people and the manner in which they deal with this. As the world deals with the physical health, financial, and social consequences of the pandemic, which has claimed many lives, the mental health impact and implications cannot to be ignored.