True Heart Research Articles

Echocardiographic imaging and anatomic characteristics of true univentricular heart manifesting as double inlet - double outlet right ventricle: Case report and literature review

Echocardiographic imaging and anatomic characteristics of true univentricular heart manifesting as double inlet - double outlet right ventricle: Case report and literature review

허난설헌의 내방가사에 드러난 중국적 감성지식의 수용 방식

Heo Nanseolheon(許蘭雪軒) was a female writer in the middle of Joseon(朝鮮) Dynasty and created a number of works in which her true heart was put. Most of Heo Nanseolheon’domestic lyric are based on Chinese literary forms. This is the result of the benefits she received from his prestigious family in his youth. For this reason, it is natural that the accumulated knowledge of Nanseolheon became the foundation of his creation. Based on his accumulated creative awareness, Nanseolheon boldly used the Shiti(詩題) and Cipai(詞牌) in addition to freely using the form of Chinese literature itself. However, this is not a mere borrowing, but a complete understanding and understanding of China’s emotions. Therefore, Nanseolheon is trying to perfectly match his works with Chinese emotional knowledge. Not only that, but also in the framework of Chinese emotional knowledge that he formed, the artist’s affection melts without hesitation. Thus, the domestic lyric of Heo Nanseolheon are resurrected and revived in China after his death. And the background is that his has genuinely released his own story with the device of Chinese emotional knowledge. The distribution in China was also influenced by the background in which the artist’s voice, Heo Nanseolheon, was introduced to the familiar form and sensibility and was able to accept to accept it without any objection. Therefore, the purpose of this study is to examine the Chinese emotional knowledge and its acceptance method revealed in Heo Nanseolheon’domestic lyric. The attempt of this study has the value of examining the traces of aerodynamics that have been processed into more improved ones by accepting Chinese things.

The Approach to Sensing the True Fetal Heart Rate for CTG Monitoring: An Evaluation of Effectiveness of Deep Learning with Doppler Ultrasound Signals.

Cardiotocography (CTG) is widely used to assess fetal well-being. CTG is typically obtained using ultrasound and autocorrelation methods, which extract periodicity from the signal to calculate the heart rate. However, during labor, maternal vessel pulsations can be measured, resulting in the output of the maternal heart rate (MHR). Since the autocorrelation output is displayed as fetal heart rate (FHR), there is a risk that obstetricians may mistakenly evaluate the fetal condition based on MHR, potentially overlooking the necessity for medical intervention. This study proposes a method that utilizes Doppler ultrasound (DUS) signals and artificial intelligence (AI) to determine whether the heart rate obtained by autocorrelation is of fetal origin. We developed a system to simultaneously record DUS signals and CTG and obtained data from 425 cases. The midwife annotated the DUS signals by auditory differentiation, providing data for AI, which included 30,160 data points from the fetal heart and 2160 data points from the maternal vessel. Comparing the classification accuracy of the AI model and a simple mathematical method, the AI model achieved the best performance, with an area under the curve (AUC) of 0.98. Integrating this system into fetal monitoring could provide a new indicator for evaluating CTG quality.

Real-world validation of smartphone-based photoplethysmography for heart rate monitoring in atrial fibrillation

Abstract Introduction Photoplethysmography (PPG) based smartphone applications facilitate heart rate monitoring that may enable physicians to guide rate control in patients with atrial fibrillation (AF). Despite extensive validation of PPG-derived heart rate, validation studies in the presence of AF are lacking, particularly in unsupervised free-living conditions. Purpose To evaluate the accuracy of PPG-derived heart rate using a smartphone application in patients with an established diagnosis of AF, both during sinus rhythm and AF, in a real-world setting. Methods Consecutive patients undergoing AF ablation were enrolled four weeks prior to the procedure. They were instructed to assess their heart rate twice daily during eight weeks with a one-minute finger-over-the-camera smartphone-PPG recording. The reference heart rate was obtained from two 30-seconds handheld single-lead electrocardiogram (ECG) recordings performed immediately before and after the PPG recording. Measurements were valid if the heart rate did not change by more than 10% between the first and second ECG and maintained sinus rhythm or AF consistently. Results In total, fifty patients (age 63 ±11 years, 68% male) performed 3407 high-quality PPG measurements accompanied with two high-quality ECGs measurements both in sinus rhythm or AF. After excluding 223 measurements due to inconsistent heart rate between the first and second ECG, 3184 measurements remained. The mean heart rate (71.5 ± 17.3 beats per minute (bpm)) was significantly higher during AF (94.7 ± 19.4 bpm) compared to sinus rhythm (65.7 ± 10.7 bpm) (p-value < 0.001). The heart rate assessment was accurate within a 10% margin in 93.8% of PPG measurements. Inaccurate heart rate assessments were more frequent in AF (161/637; 25.3%) compared to sinus rhythm (35/2547; 1.4%) (p-value < 0.001). PPG underestimated the heart rate in sinus rhythm with 0.4 bpm (95% CI: -0.3 to -0.5 bpm) and in AF with 6.6 bpm (95% CI: -5.8 to -7.4 bpm). The deviation of PPG-derived heart rate from the ECG-derived true heart rate was significantly greater during AF (root mean square error (RMSE) = 11.8 bpm) compared to sinus rhythm (RMSE = 2.2 bpm) (p-value < 0.001). The heart rate correlation plots and corresponding Bland-Altman plots demonstrate a skewed underestimation of the heart rate in AF with PPG, particularly for high heart rates. Conclusions Heart rate can accurately be derived from PPG recordings using a smartphone application in real-world conditions. However, PPG measurements may underestimate high heart rates in the presence of AF.Heart Rate in Sinus RhythmHeart Rate in Atrial Fibrillation

A Textual Study of Inspirational Autobiography Wings of Fire of APJ Abdul Kalam

This research paper aesthetically focuses on Avul Pakir Jainulabdeen Abdul Kalam’s (Kalam was the 11th president of India, 2002 to 2007) early struggle for education, success and analyses how his autobiography Wings of Fire turns out to be a source of motivation for millions of people not only in India but also across the globe. The struggle of Kalam as a student and of success as a scientist is a remarkable story for millions of people. His autobiography is replete with many inspirational episodes and teachings for transforming nation and its people. The present study highlights Kala’s lessons for people to be humble, receptive, self-reliant, and resourceful and above all a true heart in course of life.

DIASTOLIC DYSFUNCTION EVALUATION IN CARDIAC AMYLOIDOSIS: BEYOND TRADITIONAL PARAMETERS TO DISCRIMINATE BETWEEN TRUE HEART FAILURE WITH PRESERVED EJECTION FRACTION AND MIMICS

Abstract Background Diastolic dysfunction in cardiac amyloidosis (CA), according to current guidelines, can be classified using mitral flow velocities, mitral annular e’ velocity, E/e’ ratio, tricuspid regurgitation jet and left atrial (LA) maximal volume. However, LA minimal volume and the ratio between LA and left ventricular (LV) volumes at end–diastole, known as left atrio–ventricular coupling index (LACI), have recently been proposed to refine prognosis and peak atrial longitudinal strain (PALS) has been demonstrated to better stratify diastolic dysfunction. Aim of the Study To evaluate, in patients with CA: 1) the role of LACI as marker of LV diastolic dysfunction; 2) whether LACI could discriminate cardiomyopathy from normal cardiac function; 3) whether LACI and/or PALS could help discriminate between true heart failure with preserved ejection fraction (HFpEF) and amyloidotic cardiomyopathy (HFpEF–mimic). Methods We retrospectively analyzed 63 patients with CA and compared them with 80 true HFpEF patients and 70 healthy people; echocardiography was performed at the time of the diagnosis and diastolic function was characterized according to current guidelines. Results In patients with CA, LACI significantly increased as diastolic dysfunction worsened (P for trend < 0.0001) and significantly correlated with LV filling pressures estimated by E/e’ ratio (beta = 0.65, P < 0.0001) and pulmonary artery systolic pressure (beta = 0.63, P < 0.0001). LACI, after adjustment for age, gender and body mass index (BMI), was significantly higher in CA [0.62 (95%CI 0.52–0.70)] and in HFpEF [0.61 (95%CI 0.55–0.68)] than in controls [0.29 (95%CI 0.19–0.39)], while the difference between the two diseased populations was not statistically significant; a cut–off value of 0.45 was able to discriminate between controls and diseased patients (sensitivity = 95%, specificity = 94%, area under ROC curve = 0.98). PALS, after adjustment for age, gender and BMI, was significantly lower in CA [11.1 (95%CI 8.4–13.8%) and 8.4 (95%CI 3.5–13.3%) respectively in ATTR and AL] than in HFpEF [17.4 (95%CI 15.6–19.3%)], and a cut–off value of 9.9% was able to discriminate between them (sensitivity = 89%, specificity = 73%, area under ROC curve = 0.86). Conclusions LACI is a novel index able to discriminate between normal and diseased patients. In CA, it shows good correlation with diastolic dysfunction and LV filling pressures. PALS can be used to discriminate between true HFpEF and CA.

A Study on Khatu Shyam Temple Rajasthan

According to Hindu religion, Khatu Shyam ji had received a boon from Shri Krishna in Dwaparyug that he would be worshiped by his name Shyam in Kaliyug. Barbarik ji's head was buried in Khatu Nagar (present-day Sikar district of Rajasthan state), hence he is called Khatu Shyam Baba. According to the story, a cow came to that place and was spontaneously releasing milk from her breasts every day. Later, after excavation, the head was revealed, which was handed over to a Brahmin for a few days. Once the king of Khatu Nagar was inspired in a dream to build a temple and to adorn that head in the temple. Subsequently a temple was constructed at that place and the head was decorated in the temple on the Ekadashi of Kartik month, which is celebrated as the birthday of Baba Shyam. The original temple was built in 1027 AD by Roop Singh Chauhan and his wife Narmada Kanwar. Abhay Singh, Dewan of Thakur, the ruler of Marwar, renovated the temple in 1720 AD on the instructions of Thakur. Khatu Shyam Ji Temple is located in Sikar district of Rajasthan and is considered one of the most important pilgrimage sites in the state. According to Hindu mythology , Khatu Shyam ji is the incarnation of Barbarik, son of Ghatotkach. It is said that devotees who chant his name with a true heart are blessed and their troubles go away , if they do so with true devotion.

Organizations with True Heart: The Role of Organizational Identity in Shaping Consumer Attributions of Corporate Responsibility to Race (CRR) Motives

ABSTRACT Guided by literature in the theory of corporate responsibility to race, organizational identity theory, and attribution theory, this study investigates the role of preexisting organizational identity in shaping consumer attributions of its CRR motives. The findings from a survey of 610 participants suggested that consumers believe that an organization has public-serving motives to join the fight against racial injustice when they observe the organization’s commitment to social justice, especially if the organization behaved morally before instituting CRR practices.

Physical Noninvasive Attacks on Photoplethysmogram by Computer Controlled Blood Pressure Cuff.

Sensor data has been used in social security and welfare infrastructures such as insurance and medical care to provide personalized products and services; there is a risk that attackers can alter sensor data to obtain unfair benefits. We consider that one of the attack methods to modify sensor data is to attack the wearer's body to modify biometric information. In this study, we propose a noninvasive attack method to modify the sensor value of a photoplethysmogram. The proposed method can disappear pulse wave peaks by pressurizing the upper arm with air pressure to control blood volume. Seven subjects experiencing a rest environment and five subjects experiencing an after-exercise environment wore five different models of smartwatches, and three pressure patterns were performed. It was confirmed in both situations that the displayed heart rate decreased from the true heart rate.

Ego Quest from Impoverishment to Reconciliation in Velina Houston’s Japanese American Play Kokoro (True Heart): A Freudian Reading

Japanese Americans’ struggle to achieve integration into the American mainstream culture has its powerful impact on their psychological well-being. Socially reserved and family oriented, the Japanese are challenged to cope with the mainstream American individualism and independence. Signs of melancholia, based on Sigmund Freud’s theories, are investigated in Kokoro (True Heart) (2004) written by the Japanese American playwright Velina Hasu Houston. The Japanese American protagonist, Yasako Yamashita, battles with cultural nonconformity and social remoteness which have provoked an aggressive superego incorporated in her mother’s ghost to govern and manipulate her world. The study aims to interrogate how the domineering superego succeeds in exhausting Yasako’s stranded ego driving her to commit parent-child suicide “oyako-shinju.” Although the suicide attempt has highlighted the problematic cultural gaps within the American society, nevertheless it has pinpointed the importance of resolving Japanese minority cultural differences. Velina Houston’s Kokoro (True Heart) does not only offer an astounding psychological insight into Japanese Americans’ battles with a melancholic ego fragmentation and deprivation indicated in symptoms of ambivalence, anxiety, compulsive repetition, sense of guilt and sense of inferiority, but it, also, advances solutions for ego reconciliation and self-conformity.

‘Quietist’ Salafis after the ‘Arab revolts’ in Algeria and Libya (2011–2019): Between insecurity and political subordination

ABSTRACT Revolutionary movements, like Salafi-jihadis, often capture public attention. However, as scholars of Salafism have long argued, quietist Salafis are the largest sub-group within, and in many ways the true heart of, Salafism in the southern Mediterranean and beyond. This article has two aims. First, it provides scholarship on Salafi groups in Libya and Algeria not tied to jihadi milieus. Second, it contributes new understandings of Salafi developments in two less-studied countries, namely Algeria and Libya. Via a comparative study of one prominent type of quietist Salafism, known as Madkhalism, in the post-2011 contexts of political transition and civil war (Libya) and limited political liberalization (Algeria), we show that whilst some Libyan Madkhalis partially constrained their rejection of taking up arms or of alliances with ideological competitors, their Algerian counterparts did not. We build on existing scholarship by explaining this divergence at the level of discrete political opportunity structures, both since and prior to the events of 2011, together with intra-Salafi framing competition and core quietist ideological convictions. Overall, we argue that Madkhalism has partially seen a bottom-up-driven shift over the last years that is likely to continue, further reshape the movement, and impact the countries in which its acolytes are embedded.

Establishment of deer heart identification method and development of the detection kit based on mitochondrial cytochrome B gene

BackgroundDeer heart is a valuable traditional Chinese medicinal material. At present, there is no functional component or symbol component for deer heart, and it is difficult to identify them by physical and chemical methods. In this study, we established deer heart identification method based on mtDNA cytb gene, and developed a deer heart DNA detection kit. ResultsThere were specific amplification bands in reference medicinal materials and true deer hearts at 194 bp, but no amplification bands in negative control and blank control. Deer heart DNA detection kit has good specificity, reproducibility and stability, and its sensitivity can reach 0.5 mg. ConclusionsThe application of the deer heart DNA detection kit is simple and easy to operate, and the results obtained using the kit is stable, which is suitable for popularization and application.How to cite: Wang Y, Zhang L, Ai J. Establishment of deer heart identification method and development of the detection kit based on mitochondrial cytochrome b gene. Electron J Biotechnol 2023;65. https://doi.org/10.1016/j.ejbt.2023.06.003.

Positive Predictive Value of International Classification of Diseases, Ninth Revision, Clinical Modification, and International Classification of Diseases, Tenth Revision, Clinical Modification, Codes for Identification of Congenital Heart Defects.

Background Administrative data permit analysis of large cohorts but rely on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM), and International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes that may not reflect true congenital heart defects (CHDs). Methods and Results CHDs in 1497 cases with at least 1 encounter between January 1, 2010 and December 31, 2019 in 2 health care systems, identified by at least 1 of 87 ICD-9-CM/ICD-10-CM CHD codes were validated through medical record review for the presence of CHD and CHD native anatomy. Interobserver and intraobserver reliability averaged >95%. Positive predictive value (PPV) of ICD-9-CM/ICD-10-CM codes for CHD was 68.1% (1020/1497) overall, 94.6% (123/130) for cases identified in both health care systems, 95.8% (249/260) for severe codes, 52.6% (370/703) for shunt codes, 75.9% (243/320) for valve codes, 73.5% (119/162) for shunt and valve codes, and 75.0% (39/52) for "other CHD" (7 ICD-9-CM/ICD-10-CM codes). PPV for cases with >1 unique CHD code was 85.4% (503/589) versus 56.3% (498/884) for 1 CHD code. Of cases with secundum atrial septal defect ICD-9-CM/ICD-10-CM codes 745.5/Q21.1 in isolation, PPV was 30.9% (123/398). Patent foramen ovale was present in 66.2% (316/477) of false positives. True positives had younger mean age at first encounter with a CHD code than false positives (22.4 versus 26.3 years; P=0.0017). Conclusions CHD ICD-9-CM/ICD-10-CM codes have modest PPV and may not represent true CHD cases. PPV was improved by selecting certain features, but most true cases did not have these characteristics. The development of algorithms to improve accuracy may improve accuracy of electronic health records for CHD surveillance.

Application of the Alivecor KardiaMobile smartphone modulated ECG device for use in horses.

Electrocardiography is the method used to monitor the electrical impulses in the heart. These diagnostics are increasingly making use of smartphone-based technologies. The objective of this research was to determine whether the Alivecor KardiaMobile (ECGAKM) smartphone-modulated electrocardiographic device, a novel ECG device, can be used to obtain reliable electrocardiogram (ECG) readings in horses. The device was initially tested in 36 Nooitgedacht pony mares to determine the best site of application, method of skin preparation, and ECGAKM device orientation for reliable ECG tracings. Once the most reliable site for ECG acquisition was determined, the device was then applied, in this manner, to 31 Nooitgedacht pony mares and compared with a standard telemetric ECG system (ECGTV). The ECGAKM device was best applied in the fourth intercostal space on the left hemithorax in a vertical orientation and with the skin dampened with 70% ethanol. Mean values determined for RR and QT intervals between the ECGAKMS and ECGTV were not significantly different, however, mean values for the duration of the QRS complexes were significantly different for the two devices. There is acceptable agreement between the ECGTV and ECGAKM devices with regards to the measurement of the PQ; RR and QT intervals but not the QRS duration. The automatically calculated heart rate is not an accurate measure of true heart rate. The Alivecor KardiaMobile (ECGAKM) device can be considered as a simplified screening ECG device in situations where the more standardised system is either unavailable or impractical, but has some limitations.

Carcass yield, non-carcass components and economic viability of using licuri oil in the diet for Santa Inês ewe’s

Background: The production of biofuels has caused an increase in the prices of agricultural commodities. Thus, the ecological footprint, social inclusion and profitability of production systems have encouraged the use of agroindustrial products as an alternative in ruminant feeds. Objective: To evaluate carcass yields, non-carcass components, and the economic viability of including licuri oil in diet of Santa Ines ewes. Methods: A total of 32 Santa Ines ewes (multiparous, non-lactating, 2–4 years old, and 36.7±0.87 kg of body weight—BW) were allotted to a randomized block design with four treatments (diets containing 0, 2, 4 or 5% licuri oil) with eight replicates per treatment, and confined for 77 days. Results: The incremental inclusion of licuri oil promoted a quadratic response on slaughter BW, carcass and true yields, chest widths, heart fat, pancreas, omental fat, and ribeye area (p<0.05). Carcass, heart and loin weight, shank yield, fat thickness and loin fat were reduced (p<0.05); while cooling losses, left half-carcass weight, saw blade yield, and proportion of meat in the loin increased (p<0.05) with increasing dietary levels of licuri oil. The control diet resulted in the best gross revenue (USD$609.39); however, there was a loss (USD$50.96) regarding economic performance indicators. Conclusion: The use of up to 2% licuri oil in the diet increased carcass yield of discard ewes.

Adaptive Nonlinear Least Squares Framework for Contactless Vital Sign Monitoring

The respiratory and heart rates are critical physiological parameters, and conventional contact-based monitoring techniques may cause discomfort and epidermal damage, being therefore inadequate for long-term monitoring. Despite recent advances, accurate contactless vital sign monitoring is still challenging in practical scenarios, especially in relation to heart rate estimation. In this work, we propose a comprehensive framework for vital sign processing in frequency-modulated continuous-wave radar systems and evaluate its performance with real data imitating common working conditions in an office environment. First, to improve the signal-to-noise ratio before estimation, we propose a novel slow-time phase correlation processing, which allows early integration of the vital sign energy at nearby range bins. Subsequently, we present an adaptive nonlinear least squares framework that explores the harmonic structure existing in the recovered displacement signal. An additional Kalman filter stage is designed to select among multiple estimates from different search regions, thus conferring adaptivity and robustness against harmonic interference and noise. This approach largely provides estimates within the predefined error intervals, being capable of tracking the true breathing and heart rate values even during continuous small body movements. The final accuracy and root mean square error values have shown enhanced estimation, outperforming conventional spectral estimation and other recently proposed methods in almost all scenarios.

Prickly Jim

Within this text, we discuss themes that cover the relationship between our personal visual art collaborations and how they relate to the heavy music scene and culture within Aotearoa. We provide background context to the origins of Prickly Jim, and display examples of the type of work we create. We explore the culture of the ‘moshpit’ in relation to our own personal experiences and the wider correspondence it has with our creative output. The pit becomes a perfect metaphor to describe the dichotomy between the aesthetics of metal and metal’s true heart. On the outside, the pit is choreographed violence, intimidating to the uninitiated. On the inside, there is a profound sense of community and belonging. Yes, we punch and shove each other, but it is in a way that could only be described as endearing.

珠荈 金順香의 茶情神과 茶法 硏究

This paper researched the meaning of Haengda through Jucheon's tea culture activities and the tea spirit of her, who is actively continuing the tea tradition in Busan, the center of modern tea culture. Jucheon’s spirit of tea, which emphasized the sincerity of character in harmony, tried to find the true mind hidden deep in one's heart through doing Haengda so that one could learn and reflect on one's own accord. In addition, while drinking tea through Haengda, the miscellaneous delusions disappear and people find their true heart hidden deep in mind. The cultivation of the mind that concentrates all minds to eliminate miscellaneous thoughts, and is not led by other delusions, which is what we consider as ‘禪’(Zen) of our tea life. In other words, Jucheon's principle of the ‘Joosim Dabeop’ goes beyond the tea ceremony spirit and communicates with the compassionate mind that seeks the universal true entity. In addition, by actively participating in tea ceremony education at local universities and high schools, companies and organizations, as well as various tea culture events for the development of tea culture, Jucheon has came into the limelight as an important person in modern tea culture. She is taking the lead not only in tea culture activities but also in activating the national interest for the succession and development of Jogakbo as first traditional Jogakbo making successor in Korea, which has been somewhat neglected even in the traditional culture sector. As mentioned above, by examining the footsteps of Jucheon, who has been instrumental in transmitting Korean tradition so far, in the hopes of re-recognizing the value of our tea culture and spreading the excellence of traditional and Korean tea culture to the domestic and worldwide, it makes us think again about the role we have to go forward to transmit and develop of our traditional culture.

Evolution of the glomerulus in a marine environment and its implications for renal function in terrestrial vertebrates

Nearly a century ago, Homer Smith proposed that the glomerulus evolved to meet the challenge of excretion of water in freshwater vertebrates. This hypothesis has been repeatedly restated in the nephrology and renal physiology literature, even though we now know that vertebrates evolved and diversified in marine (saltwater) environments. A more likely explanation is that the vertebrate glomerulus evolved from the meta-nephridium of marine invertebrates, with the driving force for ultrafiltration being facilitated by the apposition of the filtration barrier to the vasculature (in vertebrates) rather than the coelom (in invertebrates) and the development of a true heart and the more complex vertebrate vascular system. In turn, glomerular filtration aided individual regulation of divalent ions like magnesium, calcium, and sulfate compatible with the function of cardiac and skeletal muscle required for mobile predators. The metabolic cost, imposed by reabsorption of the small amounts of sodium required to drive secretion of these over-abundant divalent ions, was small. This innovation, developed in a salt-water environment, provided a preadaptation for life in freshwater, in which the glomerulus was co-opted to facilitate water excretion, albeit with the additional metabolic demand imposed by the need to reabsorb the majority of filtered sodium. The evolution of the glomerulus in saltwater also provided preadaptation for terrestrial life, where the imperative is conservation of both water and electrolytes. The historical contingencies of this scenario may explain why the mammalian kidney is so metabolically inefficient, with ∼80% of oxygen consumption being used to drive reabsorption of filtered sodium.

TAMPONADE WAS ONLY A FACADE: CANCER WAS THE REAL ANSWER

TAMPONADE WAS ONLY A FACADE: CANCER WAS THE REAL ANSWER