AbstractEl Niño‐Southern Oscillation (ENSO) is the dominant atmosphere–ocean coupled mode of year‐to‐year variations in the tropical Pacific. It shows diverse spatiotemporal characteristics and casts major influences on seasonal predictions of global weather–climate extrema. Despite numerous dynamical and statistical models for ENSO prediction and predictability studies, they are commonly subjected to one‐to‐three issues among less skillful simulation of El Niño diversity, huge requirements of computational resources and a low robustness in statistics. Here, an efficient deep‐learning model involving nonlinear coupling of multiple variables is independently developed to study the predictability of two types of El Niño events related to initial uncertainty, which is the first kind of predictability problem. The model can skillfully simulate statistically robust features of observed El Niño diversity in terms of periodicity, amplitude, and seasonal phase‐locking. Using this model, we have revealed mathematically several new types of fastest‐growing initial errors in two types of El Niño predictions based on a novel concept of conditional nonlinear optimal perturbation (CNOP), especially including one that can strengthen central Pacific types of events, which is rarely investigated before. Moreover, CNOPs are superimposed into a numerical model, GFDL CM2p1, for comprehensive validation and growth mechanism mining, which demonstrates the consistent dynamical evolution of initial errors in both numerical and AI models. Our study represents the first attempt to explore the first kind of ENSO predictability problem from perspectives of nonlinear error‐evolving dynamics using a data‐driven model. This is of great importance as it offers us sufficient confidence to perform ENSO‐related (such as the Madden–Julian Oscillation, etc.) mechanisms and predictability studies in the future without strongly relying on dynamical numerical models.