Trophoblastic Embolism Research Articles

Incidental pulmonary trophoblastic embolism in a chinchilla

This case study presents the pathomorphological description of a pulmonary trophoblastic embolism in a female chinchilla, which died due to respiratory distress. Routine necropsy examination revealed the presence of multiple small and grey coloured foci, which presented with a hyperaemic and multifocal appearance on the surface of the lungs. Samples taken from the lung tissue were subjected to routine tissue processing and stained with haematoxylin-eosin (HE) and periodic acid-Schiff (PAS) reagents. Histopathological examination demonstrated one or more giant cells with rather large nuclei and a broad cytoplasm in the alveolar capillaries, which appeared as multifocal areas. These cellular structures were positive for PAS staining. And also, lymphocytic and histiocytic inflammatory cells infiltration were observed around the alveoli and bronchi-bronchioles

EMBOLISMO TROFOBLÁSTICO E INSUFICIENCIA RESPIRATORIA AGUDA. PRESENTACIÓN DE TRES CASOS

Se presenta tres casos de muerte por insuficiencia respiratoria aguda, severa, asociados a embolismo trofoblástico, en pacientes portadoras de mola hidatidiforme. Se discute la significación de la lesión como un proceso inflamatorio agudo.

Fatal trophoblastic embolism during cesarean section

Fatal trophoblastic embolism during cesarean section

Respiratory complications of pregnancy.

The pregnant woman is susceptible to a variety of respiratory complications. When a pregnant patient presents with an abnormal chest x-ray or a pulmonary complaint, an understanding of the pathophysiology of pregnancy will guide the clinician in establishing a diagnosis. Pregnancy brings about many changes to a woman's body. One of the more intriguing is a decrease in the T helper cells, resulting in a state of relative immunosuppression. Despite this, the prevalence of infectious pneumonia is not increased in pregnancy. Complications from pneumonia, however, are increased in the pregnant host. Most notably are increases in both mortality related to influenza infection and the risk for dissemination of coccidioidomycosis. Other physiologic changes predispose the pregnant woman to certain disease processes. Hypercoagulability associated with pregnancy results in a marked increase in the incidence of thromboembolic disease. Although rare, pregnancy is also associated with other embolic phenomena including amniotic fluid embolism, air embolism, and trophoblastic embolism. Because of the increases in intravascular volume and cardiac output that occur in pregnancy, women with underlying structural heart disease will frequently present for the first time or have an exacerbation of their disease. This is especially true of mitral stenosis. Peripartum cardiomyopathy also can occur, and for the majority of patients, the heart remains damaged for life. Finally, although uncommon, lymphangioleiomyomatosis will often present or become exacerbated during pregnancy. Patients with this disorder need to be counseled concerning the increased risk associated with pregnancy. This paper reviews the various respiratory complications associated with pregnancy.

Sudden death from trophoblastic embolism in pregnancy

A case of a 24-year-old multigravida, with dry cough, dyspnea, fatigue, and weight loss with normal foetal growth rate is reviewed. Upon admission the patient suddenly became tachycardic, tachypnoic, cyanotic, followed by a non-palpable peripheral pulse, and asystole unresponsive to resuscitation. The autopsy revealed massive pulmonary trophoblastic embolism, bilateral pregnancy luteoma, and accelerated placental maturation. Trophoblastic embolism should be taken into consideration whenever cardiorespiratory emergency develops during pregnancy.

Syncytial trophoblastic embolism associated with placenta increta and pre-eclampsia

Syncytial trophoblastic embolism associated with placenta increta and pre-eclampsia

Pulmonary thrombotic and trophoblastic embolism in early pregnancy.

Pulmonary thrombotic and trophoblastic embolism in early pregnancy.