Objective: this study is to assess the efficacy of antibiotics against topical steroids in the treatment of recurrentsinusitis, with an emphasis on symptom relief, recurrence rates, and patient satisfaction.Study Design: a prospective study.Duration and Place of Study: This study was conducting at Department of ENT at Hayatabad MedicalComplex between Jan 2020 to Jan 2021.Materials and Methods: This study included 175 patients between the ages of 18 and 65 who had recurrentsinusitis. Patients were randomly assigned to two groups: Group A got antibiotics, whereas Group B received topicalsteroid treatment. Validated rating methods were used to measure symptom intensity, recurrence rates, and patientsatisfaction at baseline, 4 weeks, and 12 weeks following therapy beginning. The following information was gathered:medical history, clinical examination, endoscopic results, and radiographic examinations. To compare the results ofthe two treatment groups, the obtained data were analyzed using relevant statistical techniques such as t-tests andchi-squared tests.Results: Of 175 patients, 88 got antibiotics and 87 topical steroids. The average age of antibiotic patients was 44.2± 8.1 years, whereas topical steroid patients averaged 43.9 ± 7.8 years. Both groups had identical baseline scores:antibiotics scored 7.2±1.5 and topical steroids scored 7.4±1.4. Both treatment groups’ 12-week patient satisfactionand recurrence rates were examined. 65.9% of antibiotic patients were pleased, 26.1% moderately satisfied, and7.95% unhappy. In contrast, 85.05% of topical steroids patients were satisfied, 13.8% moderate, and 1.14% poor.These data demonstrate topical steroids may reduce chronic sinusitis patients’ symptoms, satisfaction, and recurrence.Conclusion: This comparative research shows that topical steroids relieve symptoms quicker and longer, have a reducedrecurrence rate, and increase patient satisfaction. These findings suggest that topical steroids may help treat recurrentsinusitis and suggest that further study and clinical recommendations are needed to improve therapy.Keywords: recurrent sinusitis, antibiotics, topical steroids, drug therapy, comparative study, symptom improvement,recurrence rates, patient satisfaction.