Treatment Of Pediculosis Capitis Research Articles

Effectiveness of Topical 0.5% Ivermectin Shampoo in the Treatment of Pediculosis Capitis among School-going Female Children.

Background:Pediculosis is a common ectoparasitic infestation in children. There are different treatment modalities that have been used in the treatment of pediculosis capitis from time immemorial, each with their own shortcomings. Increasing emergence of resistance to permethrin has led to the lookout for newer alternatives.Aims and Objectives:The role of topical ivermectin in the management of pediculosis in people with culturally different hair grooming practices is analyzed in this study.Materials and Methods:This observational open-label clinical study was conducted in September–November 2019 in the schools that were under the rural health center at South India among school-going female children aged between 13 and 16 years of age and diagnosed with pediculosis.Results:This study demonstrated that a single application of ivermectin shampoo was able to kill head lice in 86.2% of the participants. In participants with persistent infection (13.8%), a repeat application killed the entire louse and 100% efficacy was demonstrated. Topical ivermectin is devoid of systemic side effects of oral ivermectin. Topical ivermectin has found to be more effective than contemporary recommended agents such as malathion and permethrin.

Comparison of Oral Ivermectin and Permethrin 1% Shampoo in the Treatment of Pediculosis Capitis

Objective: To compare the efficacy of Oral Ivermectin with Permethrin 1% Shampoo in the treatment of Pediculosis Capitis
 Study Design: Randomized controlled trial
 Setting & Study duration: This study was conducted at the Department of Dermatology, Bolan Medical College/ Sandeman Provincial Hospital, Quetta from December 24, 2016 to June 23, 2017 (6 months)
 Materials and Methods: All children of either gender having age 5 and above weight more than
 15 kg presented with head-lice infestation confirmed by combing the wet hair with a fine-toothed detection comb were enrolled. All patients were randomly allocated into two groups. Patients in group A received oral Ivermectin in dose of 200mcg/kg while patients in group B received application of 1% Permethrin Shampoo. They were called after one week and they received second dose of oral Ivermectin in same dose of 200mcg/kg and application of Permethrin 1% Shampoo and re-evaluated after one week. Treatment was considered effective by absence of live lice by day 15 of treatment.
 Data was analyzed in SPSS version 17.Mean age of the patient in the sample was calculated. Male to female ratio was determined in the sample. In both the groups, frequency of patients having no live louse in the head on 15th day was calculated. The frequency in both groups was compared by applying chi square test keeping p-value≤ 0.05.
 Results: Majority of the patients presented were females in both group, i.e. 20 (66.7%) and 23 (76.7%) respectively. Insignificant difference was observed in the mean age in between group (p- value 0.482). Efficacy was found significantly higher in oral Ivermectin group 26 (86.7%) as compared to 1% Permethrin Shampoo. (p-value <0.001).
 Conclusion: The efficacy of oral Ivermectin group was considerably higher as compared to 1% Permethrin Shampoo in our cohort.

Topical ivermectin in the treatment of pediculosis capitis

Background: Head lice infestation is considered a prominent issue because of its worldwide distribution, especially among children. Millions of children are infested with pediculosis capitis every year. The increasing rate of lice infestation has been reported even in the developed countries due to the resistance to known pediculicides. Besides, the louse is a vector for serious diseases, such as epidemic typhus fever. Objective: The aim of this work was the search for a new cheap and effective drug for pediculosis capitis. 2% ivermectin solution, a promising novel drug used for endoparasite and ectoparasite infections, was used in this study. Materials and Methods: This was a clinical trial study. The in vitro study was carried out in a period of five months. Samples of nits and lice were collected from female patients of the Department of Dermatology and Venereology, Baghdad Teaching Hospital. The study was conducted during a period from October 2002 through November 2003. One hundred fifty children from four primary schools in Hayy Al-A’amel, Baghdad, participated in this part of the study. The preparation was applied to the children by the author. One hundred children were tested with ivermectin solution and fifty children with rectified spirit. The first part of the study involved a parasitological evaluation (in vitro study) of pediculicidal and ovicidal activity, in which 4% ivermectin solution was discontinued because of contact dermatitis. Therefore, 2% ivermectin solution was used instead. Pediculicidal and ovicidal activity was examined half an hour afterward. The second part of the study involved a clinical evaluation (in situ study) of 2% ivermectin solution for half an hour. Results: Topical 2% ivermectin solution in rectified spirit is a good pediculicidal (100%) and a good ovicidal (88%) drug with good therapeutic efficacy (82% after the first application, 90% after the second application) against pediculosis capitis. Conclusion: The study described a novel topical preparation for pediculosis capitis, which was proven effective and safe.

Comparison of efficiency of 1% permethrin lotion vs. 0.5% ivermectin shampoo in the treatment of pediculosis capitis

<p class="abstract"><strong>Background:</strong> Pediculosis or head louse infestation is a common condition and an issue of concern in developing countries. Various treatment options are available for the management of this condition but still needs further research due to drug resistance. This study seeks to compare the efficacy of 1% permethrin lotion and 0.5% ivermectin shampoo in the management of pediculosis capitis.</p><p class="abstract"><strong>Methods:</strong> A prospective longitudinal study was conducted in a tertiary care hospital from September 2013 to June 2015. Patients presenting with pediculosis capitis infestation were divided into two groups of 50 each. They were treated with either topical 1% permethrin lotion or 0.5% ivermectin shampoo. Follow up was done once in 4 weeks on the extent of head lice infestation.<strong></strong></p><p class="abstract"><strong>Results:</strong> After being treated with either topical 1% permethrin or 0.5% ivermectin shampoo, the presence of nits decreased significantly in the ivermectin group. Number of patients either had no nits or less than 5 dead nits in the permethrin group than in the ivermectin group.</p><p class="abstract"><strong>Conclusions:</strong> It is concluded that both 1% permethrin and 0.5% ivermectin have comparable efficacies in managing pediculosis capitis infestation, but permethrin was found to be more effective in treatment. In addition, none of the participants in both the treatment groups experienced any side effects. This is one of the very few studies exploring the treatment efficacy of topical ivermectin and the potential scope for future studies on the treatment options for pediculosis capitis.</p>

Efficacy and safety of Illicium verum (star anise) fruit oil extract shampoo compared to permethrin 1% shampoo in the treatment of pediculosis capitis among Filipino children and adults: A randomized controlled trial

Efficacy and safety of Illicium verum (star anise) fruit oil extract shampoo compared to permethrin 1% shampoo in the treatment of pediculosis capitis among Filipino children and adults: A randomized controlled trial

Treatment of Pediculosis Capitis.

An endeavour to delineate the salient details of the treatment of head lice infestation has been made in the present article. Treatment modalities including over the counter permethrin and pyrethrin, and prescription medicines, including malathion, lindane, benzyl alcohol, spinosad are discussed. Salient features of alternative medicine and physical treatment modalities are outlined. The problem of resistance to treatment has also been taken cognizance of.

Spinosad: An effective and safe pediculicide

Although head lice are not a major health hazard, they have been a source of irritation and disgust for thousands of years. Despite the use of over-the-counter (OTC) treatments, it has high prevalence, and epidemics occur regularly. Permethrin 1% is currently recommended as a drug of choice, but many areas have shown resistance to this insecticide. A 0.9% suspension of spinosad, a naturally occurring pest control product, has recently been approved by the USFDA for treatment of pediculosis capitis. It acts by enhancing the action of nicotinic acetylcholine, resulting in paralysis of the parasite. Clinical trials show that spinosad is more effective and safe than current drugs of treatment. Additionally, it does not require nit combing. Spinosad appears as a powerful recruit in the battle against head lice.

Treatment of pediculosis capitis with topical albendazole

Pediculosis capitis, or head lice infestation, caused by Pediculus humanus capitis, is a common and ubiquitous health concern. Increasing resistance and treatment failures are reported with available topical pediculicides and may prove challenging to manage. Recent data indicate that the oral anti-helmintic agents thiabendazole and albendazole could represent new therapeutic options against pediculosis capitis. We report a novel treatment modality in four patients with head lice who were successfully treated with a topical application of albendazole.

Albendazole: Single or Combination Therapy with Permethrin against Pediculosis Capitis

Pediculosis capitis is a worldwide problem and a growing concern because of resistance to pediculicides. In the present study, we investigated whether albendazole could be used in the treatment of pediculosis capitis in combination with 1% permethrin or alone. A total of 150 children were randomly divided to five groups of 30 each. Group 1 got albendazole in a single dose (400 mg), group 2 got albendazole at 400 mg for 3 days, group 3 was given 1% permethrin, group 4 took 1% permethrin and albendazole in a single dose (400 mg), and group 5 got 1% permethrin and albendazole in a dose of 400 mg for 3 days. Groups given albendazole were also given another 400 mg dose of albendazole after 1 week. The success rate of treatment at the 2-week follow-up for all groups was 61.5%, 66.6%, 80.0%, 84.6%, and 82.1%, respectively. No statistically significant difference was found between the groups. The results of this study suggest that albendazole is effective against pediculosis capitis and there is no synergistic effect between albendazole and 1% permethrin.

Treatment of ectoparasitic infections: review of the English-language literature, 1982-1992.

We reviewed the English-language literature of 1982-1992 for papers concerning scabies, pediculosis, and their treatments; this information was supplemented with opinions of workers in the field of ectoparasitic disease. Six treatment trials for scabies, one study of the treatment of pediculosis pubis, and additional studies on the treatment of pediculosis capitis were included. Both lindane 1% and permethrin 5% are effective treatments for scabies, although resistance to lindane does exist. Lindane 1%, permethrin 1%, and pyrethrins with piperonyl butoxide are all effective treatments for pediculosis. Severe reactions to lindane therapy may occur when increased skin absorption of lindane occurs. Permethrin 5% or lindane 1% is recommended for the treatment of scabies. Lindane should be used with precautions to avoid excess skin penetration and should not be used to treat infants, young children, or pregnant or lactating women. Permethrin 1%, lindane 1%, or pyrethrins with piperonyl butoxide is recommended for the treatment of pediculosis pubis. Pregnant and lactating women should be treated with either permethrin or with pyrethrins containing piperonyl butoxide.

Pyriderm shampoo in the treatment of Pediculosis capitis

112 patients with head lice were treated with a shampoo containing pyrethrins. All were treated twice with an interval of one week. At examination immediately before the second treatment, 6 patients had small, newly hatched lice, and one patient had both small and mature lice--probably due to reinfestation. This patient was lice-free after the third treatment, the other patients after the second treatment. It is concluded that pyrethrins are highly effective against head lice and have the advantages of a low toxicity to mammals and a short contact time.

Treatment of Pediculosis Capitis

Treatment of Pediculosis Capitis

Treatment of Pediculosis Capitis with D.D.T

Treatment of Pediculosis Capitis with D.D.T

Treatment of Pediculosis Capitis

Treatment of Pediculosis Capitis

Treatment of Pediculosis Capitis

Treatment of Pediculosis Capitis

The Treatment of Pediculosis Capitis

The Treatment of Pediculosis Capitis