Treatment Of Osteomyelitis In Children Research Articles

The surgical treatment of chronic recurrent hematogenous osteomyelitis in children

The surgical treatment of chronic recurrent hematogenous osteomyelitis in children

Role of Trimethoprim-sulfamethoxazole for Treatment of Acute Osteomyelitis in Children

Role of Trimethoprim-sulfamethoxazole for Treatment of Acute Osteomyelitis in Children

Role of Trimethoprim-sulfamethoxazole for Treatment of Acute Osteomyelitis in Children

Role of Trimethoprim-sulfamethoxazole for Treatment of Acute Osteomyelitis in Children

Conservative Treatment of Chronic Recurrent Multifocal Osteomyelitis in Children

The experience in diagnosis (52 patients) and treatment (35 patients) of chronic recurrent multifocal osteomyelitis in children is presented. In 17 patients conservative treatment was accompanied by surgical intervention. Eighteen patients received the conservative treatment only. Analysis covering medical documentation and authors observation showed that antibacterial therapy that was performed both before hospitalization of patients to CITO (20 patients) and at the institute (21 patients) was ineffective. Original scheme of conservative treatment with application of hormonal, nonsteroid antiinflammatory and metabolic therapy is given. Long term complex therapy proved sufficiently high efficacy of that treatment method and allowed to overcome the pessimism in prognosis of that disease.

Treatment of osteomyelitis in children

Acute hematogenous osteomyelitis is one of the formidable purulent surgical diseases in children. About 75% of cases of acute hematogenous osteomyelitis occur in childhood. The frequency of hematogenous osteomyelitis in children is 2.2-10% of all surgical diseases, and 12.2% of all purulent-septic diseases.

Die heutige Therapie der chronischen Osteomyelitis (Osteitis) im Kindesalter

The article reports on experience collected in the treatment of chronic osteomyelitis in children. Surgical procedure is described and attention is paid to indication and treatment with gentamycin polymethylmethacrylate chains. In 15 cases treated by the author, primary cure was achieved by this method in 13 children; additional surgical procedure became necessary in two cases.

Clindamycin in the Treatment of Osteomyelitis in Children

Clindamycin phosphate was used in the treatment of 29 children with osteomyelitis of whom 25 had an acute and four a chronic type of infection. The usual dose was 50 mg/kg/day intravenously for approximately three weeks followed by oral clindamycin palmitate at home in a dose of 30 mg/kg/day for an additional six weeks. Staphylococcus aureus was isolated in 22 of 29 cases: 96% of strains were penicillin resistant. The clinical and bacteriologic results in the present series were good to excellent. There was prompt clinical and bacteriologic response shortly after initiation of clindamycin therapy. Good bone penetration of the drug was observed. Long-term evaluation revealed satisfactory clinical and roentgenographic progress in all patients. No diarrhea or manifestations of enterocolitis appeared in any patient in spite of high doses of the drug for intervals up to nine weeks.