Treatment Of Chronic Rhinosinusitis In Children Research Articles

Chronic rhino-sinusitis treatment in children with cystic fibrosis: A cross-sectional survey of pediatric pulmonologists and otolaryngologists

ObjectivesChildren with cystic fibrosis (CF) have a high incidence of chronic rhinosinusitis (CRS); however, no clinical care guidelines currently exist for the management of CRS in these patients. As a result, there is variation in the treatment of CRS in children, especially when it comes to the frequency of surgery for nasal polyposis. MethodsA 28-question survey was sent to pediatric otolaryngologists (POs) and pulmonologists (PPs) who care for pediatric CF patients. Questions assessed the level of agreement that practitioners had with various approaches to CRS care in pediatric CF patients. ResultsResponses from 114 POs and 50 PPs were included in our final analysis. Each group demonstrated significantly different approaches to the medical and surgical management of CRS in pediatric CF patients. POs prefer multi-modal approach while PPs prefer single-modal approaches. With respect to medical management, PPs incline towards IV antibiotics while POs tend toward oral steroids. ConclusionPOs and PPs strongly agree that CRS has an impact on overall disease state and quality of life of pediatric CF patients. However, POs and PPs significantly differ in their approach to treating CRS, demonstrating a potential need for clinical care guidelines for the management these common sequelae of CF.

Clinical curative effect and safety of balloon sinuplasty in children with chronic rhinosinusitis

ObjectiveBalloon Sinuplasty for the management of paranasal sinus inflammatory diseases was introduced in otolaryngology in 2005. Over the past decade, evidence strongly supports its safety and efficacy for the treatment of chronic rhinosinusitis (CRS) in adults. Because it requires no bone or tissue removal, this procedure could be suitable in children. We present our initial experience of its use for the treatment of CRS in children. Materials and methodsA prospective study was performed of 30 children with failed medical therapy, who were scheduled for surgery. They underwent treatment by balloon sinuplasty of selected sinuses. Data were collected, including age, VAS score, CT score, and nasal endoscopy findings. ResultsThe procedure was successful in 61/65 sinuses (93.84%). Balloon sinuplasty improved sinus-related quality of life scores as well as computed tomography (CT) and endoscopic findings for up to 1 year after operation (p < 0.05). ConclusionIn this initial study, balloon sinuplasty showed a clinical curative effect in the treatment of children with refractory CRS, and was relatively safe. Structural abnormalities in sinus ostia and hypoplastic sinuses may not be amenable to balloon catheter sinuplasty.

The role of sinus surgery in children

To critically review the current literature discussing the outcome of endoscopic sinus surgery (ESS) in children with chronic rhinosinusitis (CRS). Literature review. PubMed database and the Cochrane Library were searched. The PubMed search included all English-language literature published between January 1990 and July 2012 discussing the role of ESS in children with CRS. Studies that included patients with cystic fibrosis, primary immunodeficiency disorders, or ciliary dysmotility disorders were excluded. Of the 507 articles retrieved from the primary research strategy, 11 studies were included for further discussion. There were no randomized controlled studies. The rate of success of pediatric ESS ranged from 82% to 100% in selected patients. Children undergoing ESS for CRS usually have more severe disease compared to those who get medical treatment or adenoidectomy. The extracted rate of complication was 1.4%, with no cases of cerebrospinal fluid leak or major orbital injury such as hematoma or blindness reported. ESS offers a surgical alternative in the treatment of CRS in children with an excellent safety profile. There remains a need for higher level studies addressing the indications of ESS in children.

Leczenie zapalenia zatok przynosowych u dzieci

Acute rhinosinusitis (ARS) is most often viral in aetiology and self-limited. Antibiotic therapy seems to accelerate resolution of ARS in children but whether an acceleration of improvement of the antimicrobial symptoms with antibiotics in these children is worth the increased risk of resistance remains to be determined. Intranasal steroids might have a beneficial ancillary role in the treatment of ARS. There is really no good evidence to support the use of ancillary therapies decongestants (oral or intranasal), antihistamines, and nasal irrigation in the treatment of ARS in children. Therefore available data does not justify the use of short-term oral antibiotics, intravenous antibiotics alone for the treatment of chronic rhinosinusitis (CRS) in children. There might a place for longer-term antibiotics for the treatment of CRS in children. Nasal corticosteroid treatment is a first line treatment in CRS with and without nasal polyps in children. We reserve the use of antihistamines and leukotriene modifiers for children with documented allergic rhinitis. The most supported surgical approach to the child with CRS who has failed maximal medical therapy probably consists of an initial attempt at an adenoidectomy with a maxillary sinus wash plus/minus balloon dilation followed by FESS in case of recurrence of symptoms. An exception to this statement are children with cystic fibrosis, nasal polyposis, antrochoanal polyposis, or AFS where FESS to decrease disease burden is the initial favoured surgical option.

Balloon Catheter Sinuplasty in Young Children

Background Balloon catheter sinuplasty (BCS) for chronic rhinosinusitis (CRS) was found to be successful in adults. The safety and feasibility of BCS in children has been recently established. The purpose of this study was to study the outcome of this technology in CRS in children. Methods A prospective, multicenter, nonrandomized evaluation was performed on patients with CRS. Thirty-two children between the ages of 2 and 11 years were enrolled. Safety was assessed by rate of adverse events. Effectiveness was assessed using the Sino-Nasal (SN)-5 quality-of-life questionnaire for children with CRS at 52 weeks follow-up. Results Thirty-two children were enrolled of which 24 completed their 52 weeks follow-up. No adverse events were reported because of the procedure. SN-5 score improved from a mean of 4.9 at baseline to a mean of 2.95 at 52 weeks (p &lt; 0.0001). Twelve (50%) children had a significant improvement of their SN-5 (&gt; – 1.5), 7 (29%) had moderate improvement (&gt; –1.0 and &lt; –1.5), 2 (8%) had mild improvement (&gt; –0.5 and &lt; –1.0), 1 (4%) remained the same, and 2 (8%) had worsening scores. Conclusions Balloon catheter dilation of the sinus ostia in children was safe and a significant number showed improvement of their SN-5 at 1 year follow-up. Additional studies comparing balloon sinuplasty to other modalities of treatment in children are needed to determine its efficacy in the treatment of CRS in children.

Balloon catheter sinuplasty in young children.

Balloon catheter sinuplasty (BCS) for chronic rhinosinusitis (CRS) was found to be successful in adults. The safety and feasibility of BCS in children has been recently established. The purpose of this study was to study the outcome of this technology in CRS in children. A prospective, multicenter, nonrandomized evaluation was performed on patients with CRS. Thirty-two children between the ages of 2 and 11 years were enrolled. Safety was assessed by rate of adverse events. Effectiveness was assessed using the Sino-Nasal (SN)-5 quality-of-life questionnaire for children with CRS at 52 weeks follow-up. Thirty-two children were enrolled of which 24 completed their 52 weeks follow-up. No adverse events were reported because of the procedure. SN-5 score improved from a mean of 4.9 at baseline to a mean of 2.95 at 52 weeks (p < 0.0001). Twelve (50%) children had a significant improvement of their SN-5 (>-1.5), 7 (29%) had moderate improvement (>-1.0 and <-1.5), 2 (8%) had mild improvement (>-0.5 and <-1.0), 1 (4%) remained the same, and 2 (8%) had worsening scores. Balloon catheter dilation of the sinus ostia in children was safe and a significant number showed improvement of their SN-5 at 1 year follow-up. Additional studies comparing balloon sinuplasty to other modalities of treatment in children are needed to determine its efficacy in the treatment of CRS in children.

Correlation between SN‐5 and computed tomography in children with chronic rhinosinusitis

Symptom score questionnaires for evaluation of chronic rhinosinusitis (CRS) in adults does not correlate with computed tomography (CT) scan scores of paranasal sinuses. The SN-5 is a validated symptom score questionnaire for the evaluation of CRS in children. The purpose of this study is to evaluate the correlation of the SN-5 with the CT score in children. Retrospective review of prospectively collected data. Thirty-two children between the ages of 2 years and 12 years were seen prospectively for symptoms of CRS. The mean age was 7.7 years (range, 3.6-11.5; SD = 2.4). The caretakers completed the SN-5 during their visit when a CT scan of the paranasal sinuses was obtained. The mean SN-5 score was 4.1 (SD = 1.03) and the mean Lund-Mackay CT score was 6.8 (SD = 4.3). There was a significant correlation between the SN-5 score and Lund-MacKay CT score (rho = 0.68; P < .0001) for all children in the study. Twelve (38%) children had asthma, and for those children the correlation was poorer and did not reach statistical significance (rho = 0 .57; P = .057). For nonasthmatics the correlation was stronger (rho = 0.73; P = .0003). Symptom score questionnaire (SN-5) correlated to the disease severity as measured by the Lund-MacKay CT scan score. This is different from what has been found in adults. These findings have positive implications for the follow-up of treatment of CRS in children because the frequent use of CT scans in children is discouraged due to concern for radiation exposure.

Safety and Feasibility of Balloon Sinuplasty for Treatment of Chronic Rhinosinusitis in Children

Balloon sinuplasty is a new technique that was recently introduced for the treatment of chronic rhinosinusitis (CRS). The initial experience in adults has been promising. The technique allows for restoring ventilation to the sinuses with minimal risk and trauma to the tissues. I present our initial experience of its use for treatment of CRS in children. I performed a prospective study of 30 children in whom medical therapy failed and who were scheduled for surgery. They were offered treatment with balloon sinuplasty of selected sinuses. The data collected included age, computed tomography score, and comorbid conditions. The primary outcome was the intraoperative success of dilation of the sinuses and the rate of adverse events due to the procedure. The procedure was successful in 51 of 56 sinuses (91%) in 30 children. Five sinuses, of which 4 were hypoplastic maxillary sinuses and 1 was a frontal sinus, were not amenable to dilation. No complications or side effects were noted. The initial experience with balloon sinuplasty in children seems to be very encouraging. Because there is no bone or tissue removal, the procedure seems to be suitable for use in children. A hypoplastic sinus may not be amenable to balloon sinuplasty.

Rhinosinusitis in children: the role of surgery

Indications and nature of surgery for chronic rhinosinusitis (CRS) have yet to be elucidated in children. After review of the literature and based on their experience, the authors suggest guidelines for the treatment of CRS in children. They suggest grouping children with rhinosinusitis into two groups: those with complicated acute rhinosinusitis and those with CRS. For the first group, the authors suggest an early surgical intervention because of the potential serious consequences and sometimes irreversible damage. For the second group, most agree that maximal medical management should be the first line of treatment with antibiotics, nasal lavage and as a last resort surgery. It is important to realize that surgery should be considered in these cases if medical treatment fails. Once surgery is recommended, the kind of surgery then becomes an issue between adenoidectomy, endoscopic sinus surgery or a combination of the two depending on the age and other conditions.