Treatment Of Capillary Hemangioma Research Articles

Role of Wide Excision and Cautery in Treatment of Capillary Hemangiomas in ENT

Role of Wide Excision and Cautery in Treatment of Capillary Hemangiomas in ENT

Current aspects of eyelid, lacrimal and orbital surgery in childhood

During childhood the spectrum of disorders of the eyelid, the lacrimal drainage system and the orbit as well as the subsequent therapeutic management differ from those in adults. This review outlines the clinical picture and treatment of the most common eyelid, lacrimal drainage and orbital diseases in childhood. The study comprises a PubMed literature review and own clinical results. The most common eyelid disorders in childhood include congenital malpositions, such as ptosis or entropium, which may require fast surgical correction in order to prevent amblyopia. For connatal dacryostenosis a step-by-step therapeutic approach is recommended: (1) conservative treatment using lacrimal sac massage, astringent eye and nose drops, (2) irrigation and probing of the nasolacrimal system and (3) irrigation, probing and silastic tube intubation under general anesthesia. Benign orbital lesions such as dermoid cysts can be removed at pre-school age. Using systemic beta blockers is a novel conservative approach in the treatment of capillary hemangioma, which should precede surgical interventions. Eyelid and orbital diseases during childhood may require fast surgical intervention to prevent amblyopia. Initial conservative treatment is recommended for connatal dacryostenosis and capillary hemangioma.

ПЕРЕВАГИ ВИКОРИСТАННЯ ІНФРАЧЕРВОНОЇ КОАГУЛЯЦІЇ З ДОПОМОГОЮ АПАРАТУ СТІ_3808(ПОЛЬША) В ЛІКУВАННІ КАПІЛЯРНИХ ГЕМАНГІОМ У ДІТЕЙ.

<p> В даній статті показаний 10 річний досвід та переваги використання іфрачервоної коагуляціїапаратом CTL 3808 в комплексному лікуванні капілярних гемангіом у дітей.<br /><br /></p>

Propranolol: Treatment of capillary hemangioma with orbital involvement

Clinical caseA 2-month-old girl had a fast growth hemangioma in the left side of the face, that involved upper eyelid and superior and external portion of the orbit, covering her visual axis and pushing the eye and lateral rectus muscle. We gave oral propranolol as treatment and we noticed a fast and constant hemangioma reduction and resolution of orbital and palpebral component. DiscussionAccording to previous researches, propranolol seems to be an effective and safe drug to treat capillary hemangioma. In our case, response to propranolol was satisfactory and with no side effects. This treatment should be considered as a promising alternative.

Distribution of Propranolol in Periocular Tissues: A Comparison of Topical and Systemic Administration

Oral propranolol has become a promising treatment of capillary hemangiomas (CHs) despite concerns of side effects associated with systemic beta-blockers. The objective of this study was to investigate the distribution of propranolol in periocular tissues and in plasma after topical application of propranolol as compared with intravenous and oral administration of propranolol. Each rabbit received propranolol as ophthalmic solution (1%) in one eye (1.5 mg dose), intravenous injection (1.5 mg dose), or commercially available propranolol oral solution (5 mg dose). The periocular tissues (e.g., eyelids and extraocular muscles) and blood were collected and assayed for propranolol. After topical instillation of 1.5 mg propranolol, high amounts of propranolol were rapidly delivered to the eyelids and extraocular muscles (4-32 μg/g at 1 h after dosing). The drug in these tissues was slowly cleared, and significant amounts of the drug (>0.4 μg/g) were still present at 24 h after the topical application. After oral administration of a clinically relevant dose of 5 mg propranolol, the drug concentrations in the periocular tissues were relatively low (<0.4 μg/g) at 1 h after dosing and generally undetectable at 8 h after dosing. After an intravenous injection of 1.5 mg propranolol, the drug concentrations in the eyelids and extraocular muscles were in the range of 0.2-1 μg/g at 1 h after dosing. The plasma concentration of the drug after the intravenous injection was significantly higher than that after topical application of the same dose. The higher drug concentrations in the periocular tissues of the treated eyes as compared with untreated eyes suggest direct penetration of the drug into the periocular tissues from the administration site after topical application. Topical administration can provide increased concentrations of propranolol in the periocular tissues and, thus, is superior to systemic administration for the treatment of periocular CH.

Topical Treatment for Capillary Hemangioma of the Eyelid Using β-Blocker Solution

Topical Treatment for Capillary Hemangioma of the Eyelid Using β-Blocker Solution

Treatment of capillary hemangiomas causing refractive and occlusional amblyopia

Treatment of capillary hemangiomas causing refractive and occlusional amblyopia

Treatment of capillary hemangiomas causing refractive and occlusional amblyopia

Capillary hemangiomas of the eyelid and orbit are treated when amblyopia secondary to anisometropic astigmatism or pupillary occlusion is present or when rapid growth of the hemangioma threatens to occlude the pupil. The goal of this study was to determine whether treatment of hemangiomas resolves or prevents occlusion or results in decrease in astigmatism. The records of 54 patients who underwent treatment for reduction in the size of a capillary hemangioma causing amblyopia or threatened amblyopia in two pediatric ophthalmology practices were reviewed. Twenty-eight patients were treated for amblyopia due to anisometropic astigmatism. The average amount of pretreatment astigmatism was 2.71 D, while the average amount of post-treatment astigmatism was 0.46 D. Fifteen of these patients could be tested for optotype visual acuity and all had vision acuity of 20/40 or better. Only 1 of the 15 patients treated for threatened occlusion of the pupil developed occlusion. Six of these patients cooperated with optotype visual acuity and all had vision acuity of 20/30 or better. Eleven patients were treated for pupillary occlusion. Occlusion resolved in all cases. Of the five patients treated for occlusion who cooperated with optotype visual acuity, two had a vision acuity of 20/100 or worse. Treatment to reduce the size of capillary hemangiomas results in resolution of occlusion, reduction in astigmatism, and prevention of pupillary occlusion. Those with occlusion are at higher risk for severe residual amblyopia and require prompt and definitive treatment.

Does Treatment of Capillary Hemangiomas for Amblyogenic Factors Result in a Resolution of the Amblyogenic Factors?

Factors Result in a Resolution of the Amblyogenic Factors? Shirah R. Schwartz, MD, Francine Blei, MD, Emily Ceisler, MD, Mark Steele, MD, Louis Furlan, MD, Sylvia R. Kodsi, MD; North Shore–Long Island Jewish Health System, Great Neck, NY Introduction: Treatment of capillary hemangiomas is initiated when there is amblyogenic anisometropic astigmatism, when there is pupillary occlusion, or when rapid growth of the hemangioma threatens to occlude the pupil. The goal of this study was to determine whether treatment of hemangiomas results in resolution or prevention of occlusion or decrease of astigmatism. Methods: The records of 55 patients who underwent treatment for reduction in size of a capillary hemangioma in two pediatric ophthalmology practices were reviewed. Indication for treatment, age at first visit, cycloplegic refraction at the initial and final visits, type of treatment, need for patching or spectacles, and final visual acuity were recorded. Results: This is the largest case series of children with capillary hemangiomas with recorded pretreatment and posttreatment cycloplegic refraction who were followed through the duration of treatment. Twelve patients were treated for pupillary occlusion. Occlusion resolved in all cases. Of the six patients with a final measurable visual acuity (FMVA), two had a vision of 20/100 or worse. Thirty patients were treated for anisometropic astigmatism. The average amount of pretreatment astigmatism was 2.68 D, while the average amount of posttreatment astigmatism was 0.53 D. All 15 patients with an FMVA had a vision of 20/40 or better. The 13 patients treated for threatened occlusion of the visual axis did not develop occlusion. The six patients with a FMVA all had vision of 20/30 or better. Conclusion: Treatment to reduce the size of capillary hemangiomas results in resolution of occlusion, reduction in astigmatism, and prevention of pupillary occlusion. Those with occlusion are at higher risk for severe residual amblyopia and require more aggressive treatment.

Regressionsphase als therapeutisches Ziel der kryochirurgischen Behandlung wachsender kapillärer Säuglingshämangiome

Cryosurgery is a widely accepted modality for the treatment of capillary hemangiomas of the newborn. However, no studies clearly supporting its effectivity are available. Out of 116 consecutive outpatients with 147 hemangiomas, 105 growing tumors in 91 patients were treated by cryosurgery. 13 further growing tumors were not treated because of lack of parental consent. Hemangiomas without growth within the last 2 weeks and with clinical signs of regression were not treated. After a follow-up of 1 year, the outcome of the treatment was classified as either regression (> 10% size reduction), no change (size alteration < 10%) or progression (> 10% size growth). The effectiveness of the treatment was assessed as clinical improvement of the hemangioma on an arbitrary scale per treatment session. Cryosurgery of growing hemangiomas efficiently initiated the regression phase (p < 0.05), in the most cases (68%) after a single treatment. Cryotherapy was most effective when employed in older children (p < 0.05) and for small hemangiomas (p < 0.05). Probably, this reflects associated spontaneous regression. Thus cryosurgery is a verifiably effective treatment modality for infantile capillary hemangiomas, shortening significantly their growth phase.

Orbit and adnexal neoplasia.

This article reviews the major orbital and adnexal tumors and focuses on clinical diagnosis and management. It emphasizes recent reports and reviews. Orbital tumors can be divided into vascular, mesenchymal, neural, epidermal, lymphoid, and metastatic lesions. Although derived from similar elements, the tumors of the lacrimal gland and eyelid form a separate category. Within the realm of vascular tumors, this article reviews recent literature regarding the treatment of capillary hemangiomas. It summarizes important information concerning the treatment of rhabdomyosarcomas published during the preceding year. The article also reviews case reports and studies of orbital tumors derived from neural, epithelial, and lymphoid elements. It provides general information regarding orbital metastatic disease and presents several recent case reports on lacrimal and adnexal tumors.

Pulsed-Dye Laser Treatment of Capillary Hemangiomas

Early success in the treatment of capillary hemangiomas with the pulsed-dye laser (585 nm) has fueled debate as to whether capillary hemangiomas should be treated with this new technology or left to resolve on their own, as 100% do spontaneously, usually by age 7. The greatest success has …

Capillary Hemangiomas and Treatment with the Flash Lamp-Pumped Pulsed Dye Laser

Strawberry, or capillary, hemangiomas are common vascular neoplasms, with an incidence of approximately 2.6% in neonates. They usually develop in the first few weeks of life, so that between 1 month and 1 year the incidence rises to between 8.7% and 10.1%. These lesions may grow quite large in the first year of life, and they may ulcerate or obstruct a vital organ or function. The great majority will spontaneously regress after the first year of life. Parents are often alarmed at the sight of these hemangiomas and need reassurance that the great majority will regress spontaneously. Treatments such as cryosurgery, irradiation, radium instillation, corticosteroid therapy, or surgical excision are often ineffective or cause significant morbidity. We describe 10 children with capillary hemangiomas treated with the flash lamp-pumped pulsed dye laser. The patients ranged in age from 7 weeks to 5.5 years at the beginning of laser therapy. The patients underwent 3.1 +/- 1 (mean +/- SD) laser treatments, with a mean regression of the lesions of 69.9% +/- 4.5%. All patients demonstrated some diminution in the size and color of their hemangiomas after the treatments, and there were no ill effects, such as ulceration, hemorrhage, infection, or scarring. There was no evidence of hyperpigmentation or hypopigmentation. Pulsed dye laser therapy should be considered as an option in the treatment of capillary hemangiomas, preferably prior to their full evolution. It is also a useful therapeutic approach in those hemangiomas that are slow to regress in older children.

Capillary hemangiomas and treatment with the flash lamp-pumped pulsed dye laser

• Strawberry, or capillary, hemangiomas are common vascular neoplasms, with an incidence of approximately 2.6% in neonates. They usually develop in the first few weeks of life, so that between 1 month and 1 year the incidence rises to between 8.7% and 10.1%. These lesions may grow quite large in the first year of life, and they may ulcerate or obstruct a vital organ or function. The great majority will spontaneously regress after the first year of life. Parents are often alarmed at the sight of these hemangiomas and need reassurance that the great majority will regress spontaneously. Treatments such as cryosurgery, irradiation, radium instillation, corticosteroid therapy, or surgical excision are often ineffective or cause significant morbidity. We describe 10 children with capillary hemangiomas treated with the flash lamp—pumped pulsed dye laser. The patients ranged in age from 7 weeks to 5.5 years at the beginning of laser therapy. The patients underwent 3.1 ± 1 (mean ± SD) laser treatments, with a mean regression of the lesions of 69.9% ±4.5%. All patients demonstrated some diminution in the size and color of their hemangiomas after the treatments, and there were no ill effects, such as ulceration, hemorrhage, infection, or scarring. There was no evidence of hyperpigmentation or hypopigmentation. Pulsed dye laser therapy should be considered as an option in the treatment of capillary hemangiomas, preferably prior to their full evolution. It is also a useful therapeutic approach in those hemangiomas that are slow to regress in older children. (<i>Arch Dermatol.</i>1991;127:202-205)

Treatment of capillary hemangioma by multiple excisions, skin grafts and flaps

Treatment of capillary hemangioma by multiple excisions, skin grafts and flaps

Evolution of treatment of capillary hemangiomas of the face with further observation on the value of camouflage by permanent pigment injection (tattooing).

Evolution of treatment of capillary hemangiomas of the face with further observation on the value of camouflage by permanent pigment injection (tattooing).