Treatment Of Epithelial Ingrowth Research Articles

Post-Laser In Situ Keratomileusis Epithelial Ingrowth: Treatment, Recurrence, and Long-Term Results.

To study outcomes after surgical removal of epithelial ingrowth (EI) in post-laser in situ keratomileusis patients, specifically comparing visual results and recurrence rates between 2 different EI management techniques. In this retrospective chart review of 67 eyes of 54 patients who underwent surgical treatment for EI after laser in situ keratomileusis between July 1999 and July 2014 at the Bascom Palmer Eye Institute, Miami, FL, surgical techniques, recurrence rates, visual acuity (VA), and refractive error were assessed. Of the 67 eyes, 56 eyes (83.6%) had flap lift + scraping alone, and 11 eyes (16.4%) had flap lift + scraping + suturing. After mean follow-up of 2.5 years, 11 of 56 eyes (19.6%) treated with flap lift + scraping alone had EI recurrence, whereas no eyes treated with flap lift + scraping + suturing had EI recurrence. VA results and refractive errors were better in eyes treated with lift + scraping alone compared with lift + scraping + suturing at 1 month. In the 67 eyes with 1-year follow-up, VA and refractive errors improved from preoperative values and were comparable between groups. Scraping alone provides significantly better initial visual outcomes but higher EI recurrence rates compared with scrape-suturing. Long-term visual outcomes are comparable between 2 techniques.

К вопросу о тактике лечения врастания эпителия после ЛАЗИК

К вопросу о тактике лечения врастания эпителия после ЛАЗИК

Treatment of traumatic corneal flap fold after LASIK

Objective To investigate the treatment of traumatic corneal flap fold after laser in situ keratomileusis(LASIK). Methods We opened the corneal flap which had folds by topical anesthesia. Corneal bed and corneal flap bed were rinsed and proliferative epithelial tissue was remored. We expanded and paved the corneal flap folds to make it stick to the corneal bed with dear margins. Ten patients (10 eyes)with traumatic corneal flap fold were analyzed with following-up for 6 months after surgery. Results 1. UNVA In the second day after surgery ,9 patients' uncorrected visual acuites(UNVA) were not less than 0. 6 ;In the 6 months after surgery, 9 patients' UNVA were 0. 6 ～ 1.2(0. 8 ±0. 16) ,1 patient' uncorrected visual acuity was 0. 2 with macular hemorrhage. 2. Slit lamp biomicroscopic examination. There was stromal edema around the corneal flap contusion with good contraposition in 2 cases at 1 day postoperatively. 3 cases had epithelial ingrowth around the margin with slightly swollen epithelia. The corneal flaps could restore right position after the surgical treatment for epithelial ingrowth. The corneal flap folds in all cases become flattened at 6 months postoperatively. Conclusion Traumatic corneal flap fold after LASIK can be eliminated by the timely and proper treatment. There is no serious impact on vision. Key words: LASIK; eye injuries; corneal flap; fold; treatment

Combined Mitomycin-C Assisted Photorefractive Keratectomy in the Treatment of Epithelial Ingrowth after LASIK

Combined Mitomycin-C Assisted Photorefractive Keratectomy in the Treatment of Epithelial Ingrowth after LASIK

The Treatment of Epithelial Ingrowth After Phacoemlusification Through Clear Cornea Incision

Purpose: To report a case of epithelial ingrowth treatment by surgical excision of epithelial tissues and intracameral 5-fluorouracil injection. Case summary: A 70-year-old female patient who underwent phacoemulsification through clear cornea incision in both eyes 2 years before, was referred for her left ocular pain and corneal edema of 3 months' duration. Diffuse sheet-like epithelium grew from the clear cornea incision site to the pupil margin lesion of the iris. The epithelial tissues were excised and 5-fluorouracil was injected intracamerally. There were no recurrences for 2 months.

Treatment of Epithelial Ingrowth After LASIK Enhancement With a Combined Technique of Mechanical Debridement, Flap Suturing, and Fibrin Glue Application

To report a case of clinically significant post-laser in situ keratomileusis (LASIK) epithelial ingrowth successfully treated with a combined technique of mechanical debridement, flap suturing, and fibrin glue application. A retrospective case report. A 42-year-old female patient underwent LASIK and an enhancement procedure in 1998 and 2002, respectively. Two years after her enhancement, she developed severe, visually significant epithelial ingrowth. Treatment was undertaken using a combination of mechanical debridement, flap suturing, and fibrin glue application. No recurrence was found during a 15-month follow-up period. No adverse effects were seen with this approach. Severe progressive epithelial ingrowth may be treated successfully with a combination of mechanical debridement, flap suturing, and fibrin glue application.

Transient, profound cataract associated with intracameral 5-fluorouracil

PurposeTo report a transient cataract after bleb needling and subconjunctival injection of 5-fluorouracil. DesignObservational case report. MethodsA 51-year-old man had an encapsulated bleb after filtering surgery. The bleb was needled, and 5 mg of 5-fluorouracil was injected adjacent to the bleb. ResultsWithin 5 minutes, vision fell to finger counting at 1 foot owing to anterior lens capsule opacification. The next day, acuity and lens clarity had returned to their preneedling status. Best-corrected acuity 7 months later was 20/15. ConclusionEntry of 5-fluorouracil into the anterior chamber after bleb needling can cause transient lens opacification. Recently, intracameral 5-fluorouracil was reported as a new treatment for epithelial ingrowth. Given the transient cataract observed in this case, the use of 5-fluorouracil for epithelial ingrowth should be considered with caution for phakic patients.