This literature review examines the success and effectiveness of Miniscrew-Assisted Rapid Palatal Expansion (MARPE) in adult orthodontics. Traditional methods like Surgically Assisted Rapid Palatal Expansion (SARPE) have been commonly used for treating transverse maxillary deficiencies in adults, but they come with significant drawbacks, including higher biological and financial costs. MARPE, which utilizes mini screws to apply controlled forces for palatal expansion, offers a less invasive and more precise alternative. The review analyzes several studies and reports on MARPE's success in expanding skeletal and dental structures, improving respiratory function in obstructive sleep apnea (OSA) patients, and minimizing complications like unwanted tooth movement. Despite some challenges, such as asymmetrical expansion, MARPE has demonstrated a high success rate in adult orthodontics and presents a promising treatment option. Further high-quality, long-term studies are recommended to optimize treatment protocols and evaluate potential risks.