Introduction The two most frequent causes of pancreatitis are gallstones and alcohol, accounting for 80% of cases. Other less common causes include hypertriglyceridemia, trauma, toxins, drugs and other causes. Our case highlights a patient presenting with pancreatitis due to a large hiatal hernia. Case report A 95-year-old woman with history of prior cholecystectomy and known large hiatal hernia presented with severe epigastric pain that radiates to the back. She denied alcohol use, family history of pancreatitis, new medications or trauma. Vital signs were within normal limit. Physical exam was notable for abdominal wall hernia and moderate epigastric tenderness. Lab data revealed normal LFTs, but an elevated serum lipase of 9736 U/L and amylase of 1597U/L. Computed tomography of the abdomen with contrast large hiatus hernia containing most of stomach, portions of pancreas and omentum.1423_A.tif Figure 1: CT abdomen - Coronal view Pancreas indicated by red arrow Pancreatic duct indicated by white arrow Stomach indicated by blue arrowThe patient was managed conservatively with IV fluid and parenteral analgesia. Surgical repair of the herniation was discussed, due to advanced age and resolution of symptoms, a decision to avoid operative management was made. Discussion Transhiatal herniation of the pancreas is rare due to its retroperitoneal location and fixation by the ligament of Treitz. Acute pancreatitis as a complication of this phenomenon is uncommon. Symptoms consist of pain localized to the chest and epigastrium, dyspepsia, nausea, vomiting, and dyspnea. The diagnosis is confirmed by significant serum lipase elevation and imaging evidence of pancreatic herniation with inflammatory changes suggestive of pancreatitis A variety of mechanisms have been proposed to explain hernia-associated pancreatitis. The parenchymal trauma from repetitive transhiatal sliding may itself induce pancreatitis, or it may cause intermittent ischemia. Other possibilities include volvulus formation or intermittent folding of the pancreatic duct leading to pancreatic secretion against a fixed obstruction. Historically, patients were managed with immediate hiatal hernia repair, however recent cases have demonstrated successful supportive management. Severe cases involving incarceration, perforation, or unresponsiveness to medical therapy should be managed surgically Conclusion Pancreatic herniation is a rare entity which may lead rare complications, including pancreatitis. Our case report highlights the importance of maintaining a broad differential diagnosis when approaching patients to include uncommon causes of disease entities1423_B.tif Figure 2: CT Abdomen - Sagittal View Pancreas indicated by red arrow Stomach indicated by blue arrow1423_C.tif Figure 3: CT Abdomen - Coronal View Pancreas indicated by red arrow Pancreatic duct indicated by white Stomach indicated by blue arrow
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