In this paper, a novel fuzzy neural network structure for uncertain nonlinear systems is proposed. This network is called wavelet Takagi–Sugeno–Kang (TSK) fuzzy cerebellar model neural network, which includes the framework of a cerebellar model neural network (CMNN) and the wavelet-function-based TSK fuzzy inference model. In order to effectively solve the uncertainty problem of nonlinear systems, a new structure is proposed where the wavelet function is used in the consequent parts of TSK-type fuzzy CMNN instead of the linear combination of the input variables in the traditional TSK fuzzy systems. This structure combines the advantages of the wavelet function, the CMNN and the TSK fuzzy inference system; thus, it is a more effective model for the uncertain nonlinear systems. In order to provide fast training, parameter update laws of the proposed model are derived based on the gradient descent method in which the learning-rates are online adapted. Furthermore the Lyapunov function is used to analyze the convergence of the considered systems. Finally, four different types of applications are applied to demonstrate the effectiveness of the proposed model. The simulation comparisons with other neural network models have verified the effectiveness of the new model.