The heavy global demand for sand in various sectors of the economy subjects the Vietnamese Mekong Delta to correspondingly high amounts of sand mining—a process that started in the early 1990s contributing significantly to the Vietnamese economy. The impacts of intensive sand mining and mining-related industries damage the integrity of the river and local communities. Much of the literature focuses on the former, exposing people to the deleterious implications of sand mining on the physical environment. This study aims to fill the gap on the less explored latter through the lenses of place and landscape per human geography tradition, using qualitative methods of thirty-five interviews with locals, video recordings, and sound measurements to highlight the impacts of sand mining and mining-related industries. This study revealed that sand mining and its associated activities are responsible for people’s perceptions of notable air, land, and noise pollution, as well as substantial harm to the urban environment. Over 80 percent of interviewed locals acknowledged the disruptions to their daily lives and a substantial loss of their sense of place. These findings shed light on narratives frequently overlooked by policymakers, emphasizing the urgency of addressing these issues for a sustainable future.