Total Pittsburg Sleep Quality Index Research Articles

Effect of holographic Guasha on sleep quality of older adults with hypertension in the community: A prospective study.

To explore the effect of holographic Guasha therapy on the Pittsburg Sleep Quality Index (PSQI) and Hamilton Anxiety Rating Scale (HAMA) in older adults with hypertension living in the community. This prospective study was conducted from July 2019 to December 2020. Older adults with hypertension (systolic pressure ≥ 140 mm Hg, diastolic pressure ≥ 90 mm Hg) were divided into the control and Guasha groups. The PSQI and HAMA were assessed before and after 4 weeks of intervention. 62 patients were enrolled, with 31/group (Guasha: 72.4 ± 6.9 years, 23.0 ± 3.1 kg/m2; control: 71.4 ± 6.3 years; 22.9 ± 2.9 kg/m2). The total PSQI score did not decrease in the control group after 4 weeks (from 14.8 ± 1.2 to 14.8 ± 1.8, P = .498) but decreased in the Guasha group (from 14.9 ± 1.1 to 6.8 ± 3.5, P < .001). All PSQI subscores decreased in the Guasha group after 4 weeks of Guasha intervention (all P < .05), except for the use of sleep medication, since the use of such drugs was an exclusion criterion. The HAMA index scores did not change in the control or Guasha group (both P > .05). Holographic Guasha appears to achieve better sleep outcomes than conventional treatment in improving the sleep quality of older adults with hypertension living in the community. The participants were not randomly assigned to the treatments, and the results should be confirmed in a formal trial.

The relationship between physical activity and sleep status among older adults requiring nursing care in the community

We investigated the relationship between physical activity and sleep status among older adults requiring nursing care in the community. We included 45 participants ≥65 years old (33 females; mean age, 83.2±4.4 years old) requiring nursing care. Physical activity was evaluated using the Life Space Assessment (LSA), and sleep status was measured by the Pittsburg Sleep Quality Index (PSQI) to determine the total sleep time, sleep efficiency, and PSQI total score. The physical function was measured by the timed up and go test (TUG) and grip strength. We performed a multiple regression analysis with the LSA as the dependent variable and sleep indicators (total sleep time, sleep efficiency, PSQI total score) and TUG as independent variables (demonstrating significant correlations with the LSA), and gender and age as adjusted variables. The analysis was divided into sleep time (Model 1), sleep efficiency (Model 2), and PSQI total score (Model 3). We used R commander, and < 0.05 was considered statistically significant. TUG (β=-0.375) and sleep time (β=0.383) in Model 1, TUG (β=-0.368) and sleep efficiency (β=0.570) in Model 2, and TUG (β=-0.392) and PSQI total score (β=-0.590) in Model 3 were independently selected as significant variables. In addition to TUG, sleep status, such as the sleep duration and sleep quality, was shown to be related to physical activity in older adults who require nursing care. To improve physical activity, it is necessary to consider not only the physical function but also quantitative and qualitative assessments of sleep.

The Relationship between Health-Promoting Lifestyle Behaviors and Sleep Quality of Nurses Working in the Pediatrics Clinics:

Objective: The study was conducted to determine the relationship between health-promoting lifestyle behaviors and sleep quality of nurses working in the pediatrics clinics. &#x0D; Methods: The study was conducted among nurses working in the pediatrics clinic of a training and research hospital located in X. Nurse Information Form, Health-Promoting Lifestyle Profile-II (HPLP-II), and Pittsburg Sleep Quality Index (PSQI) were applied to the nurses. Besides the descriptive statistics, Mann Whitney U test, Kruskal Wallis test, and Spearman’s Rho Correlation analysis were used for the analysis of the study.&#x0D; Results: Among the 200 nurses that were surveyed, 121 (60.5%) responded. 81% of the nurses (n=98) were female, 19% (n=23) were male, and 80.2% had a bachelor’s degree. Age average of the nurses was 25.74±3.86 years and the average weekly working hours was 49.40±7.70 hours. It was determined that total mean score of HPLP-II was 125.26±16.40 and PSQI total mean score was 12.13±2.29. The lowest mean HPLP-II subscale score was 16.19±4.64 for exercise and 17.71±3.74 for stress management. A statistically significant correlation was found between the HPLP-II total scores and PSQI total scores (r= - 0.19; p&lt; 0.05).&#x0D; Conclusion: It was determined that the health-promoting lifestyle behaviors of the nurses were above the moderate level, their sleep quality was poor, and there was a significant correlation between the health-promoting lifestyle behaviors and the sleep quality of the nurses. It can be suggested by nursing to conduct the studies determining the practices that will improve the health-promoting lifestyle behaviors of the nurses and enhance their sleep quality.

Quality of sleep in rheumatoid arthritis patients: Relationship with disease activity, depression and functional status

Aim of the workTo assess sleep quality in Egyptian patients with rheumatoid arthritis (RA) and its relationship with disease activity, depression and functional status. Patients and methodsThis cross-sectional study included 133 RA patients and 76 age and sex matched controls. Sleep using the Pittsburg Sleep Quality Index (PSQI), Beck depression inventory (BDI), functional status using health assessment questionnaire (HAQ), visual analogue scale-pain (VAS), and disease activity score (DAS28) were assessed. ResultsPatients were 125 females and 8 males with a mean age of 42.5 ± 9.5 years and disease duration of 3.9 ± 1.3 years. 76 age and sex matched control were also included. Poor sleep quality was detected in 54.1% of patients. Patients had significantly higher scores in the subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, day-time dysfunction domains and in terms of the total PSQI score compared to the control (p < 0.05). A significant difference was found between RA patients with poor sleep quality and those with good sleep quality as regards marital status, HAQ, erythrocyte sedimentation rate (ESR), VAS, DAS28, morning stiffness duration, anti-cyclic citrullinated peptide (anti-CCP) (p < 0.05), and the BDI (p < 0.001). The multivariate regression analysis found that disease activity, functional disability and depression were predictors for poor sleep quality (p = 0.04, p = 0.01 and p < 0.001; respectively). ConclusionThe sleep quality is impaired in RA patients. The poor sleep quality is associated with disease activity, depression and functional disability. Systemic psychiatric screening, holistic assessment and targeted interventions are required to improve sleep quality and quality of life.

Correlation of sleep quality with fatigue and disease activity among patients with primary Sjögren's syndrome: a cross-sectional study.

Fatigue is a frequent symptom in patients with primary Sjögren's syndrome (pSS) and can be a cause of or be associated with sleep disorders. To assess the sleep quality of pSS patients and its relationship with fatigue and disease activity. Analytical observational study conducted at an exercise psychobiology laboratory. Sleep quality was evaluated using the Pittsburg sleep quality index (PSQI) and actigraphy. Fatigue was evaluated through the Profile of Fatigue and Discomfort - Sicca Symptoms Inventory (PROFAD-SSI-SF) and a visual analogue scale for fatigue (VAS-fatigue). Disease activity was evaluated using a visual analogue scale for pain (VAS-pain), EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI) and Disease Activity Index (ESSDAI). We summarized the data through descriptive statistics. A total of 50 female patients with pSS, of average age 56.4 years, were included in the study; 80% presented low disease activity. The total PSQI score showed that 74% had poor sleep. The actigraphy showed mean sleep latency of 26.2 minutes and mean nightly awakening of 48.2 minutes (duration of wakings after sleep onset, WASO). There were correlations between PSQI and VAS-pain, VAS-fatigue, PROFAD-SSI and ESSPRI. Actigraphy showed a correlation between the duration of WASO and ESSDAI. The present study provides important information regarding correlations between sleep disorders and disease activity. There is a need for proper control over disease activity and for development of strategies to help patients to sleep better in order to diminish their fatigue.

Sleep Quality, Anxiety, and Depression in Patients With Heart Failure

Objectives: Heart Failure (HF) is a chronic condition with great impact on the lifestyle of the patients. As many as 80% of HF patients report experiencing sleep difficulties. Thus, we try to detect clinical predictors of sleep quality and define probable relationship between anxiety, depression, and sleep quality in HF patients. Materials & Methods: One hundred patients (male: 50 persons, female: 50 persons) with ejection fraction less than 45% who were hospitalized in CCU and post-CCU ward, were included in this study. Hospital Anxiety and Depression Scale (HADS) and Pittsburg Sleep Quality Index (PSQI) questionnaire were used to collect the related data. Results: The patients’ mean (SD) total PSQI score was 9.07(4.43). The most problem was seen in sleep onset latency (1.85[1.15]) sub-score of PSQI and the sleep quality of 78% of patients was abnormal. This score was higher in patients with history of abnormal blood pressure (P=0.001). PSQI score have significant correlation with anxiety (r=0.216, P=0.035) as well as depression (r=0.351, P=0.000). Conclusion: Many HF patients suffer from sleep difficulties and PSQI score seems to have significant correlation with anxiety and depression.

Evaluating the impact of adenotonsillectomy for pediatric sleep-disordered breathing on parental sleep.

To evaluate the impact of adenotonsillectomy for pediatric sleep-disordered breathing (SDB) on parental sleep quality, daytime sleepiness, and child quality of life. Prospective cohort study. Pediatric patients aged 2 to 10 years with SDB and suspected obstructive sleep apnea (OSA) requiring adenotonsillectomy were identified at a single tertiary-care pediatric otolaryngology hospital. Parental daytime sleepiness and quality of sleep were evaluated pre- and postoperatively using the Epworth Sleepiness Scale (ESS) and Pittsburg Sleep Quality Index (PSQI), respectively. Child quality of life, in the context of suspected OSA, was evaluated by the Obstructive Sleep Apnea Quality of Life Survey (OSA-18), pre- and postoperatively. Paired-samples t tests were conducted to analyze data. Forty-seven patients with a mean (standard deviation [SD]) age of 4.9 (2.2) years, participated. Mean (SD) parental age was 35.5 (4.6) years. Statistically significant decreases of 2.1 points were observed between preoperative and postoperative parental mean global ESS (P = .007; 95% confidence interval [CI]: 0.6-3.6) and mean total PSQI (P = .001; 95% CI: 0.9-3.1) scores. A statistically significant improvement (41.6 points) was observed between preoperative and postoperative on mean OSA-18 scores (P < .0001; 95% CI: 35.7-47.6). Adenotonsillectomy performed in the pediatric population for SDB, with suspected OSA, can positively impact parental daytime sleepiness and sleep quality in addition to pediatric quality of life. 2 Laryngoscope, 130:232-237, 2020.

Relationship Among the Symptom Severity of Knee Osteoarthritis, Quality of Life and Sleep Quality

Objectives: Knee osteoarthritis (OA) is a widespread disease that increases in the elderly and is an important cause of morbidity. It is common knowledge that resting and nocturnal pain is rarely seen in patients with knee OA, however latest studies showed that it is not rare. Sleep disorders are thought to be related with nocturnal pain and it is shown that in patients with arthritis are more likely to develop sleep problems. Nocturnal pain is also related with depression and decreased quality of life. This study aims to evaluate sleep quality in patients with knee OA and to reveal the relationship between severity of knee OA, pain and sleep disorders and quality of life in female and male patients. Materials and Methods: This cross sectional study includes 41 volunteer patients (27 female,14 male) between 40-65 years with knee OA, who suffer from knee pain for more than 6 months, and the study includes patients with grade 2 and 3 OA according to the Kellgren-Lawrence classification. Patients were evaluated using Visual Analog Scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Lequesne Index, Pittsburg Sleep Quality Index (PSQI), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI) and Short form-36 (SF-36). Results: VAS, WOMAC, Lequesne index, PSQI, BAI and BDI scores were significantly higher in female subjects than in male subjects. Prevalence of good sleep quality was significantly higher in male patients. There was a positive correlation between WOMAC scores and VAS, BAI and BDI scores, but there was no significant relationship between total PSQI scores. There was a positive correlation between Lequesne index scores and VAS, total PSQI, BAI and BDI scores. A negative correlation was found between WOMAC and Lequesne index and SF-36. Conclusion: Severity of knee OA is found associated with pain, depression and anxiety, sleep quality and quality of life. It should be considered to manage knee OA to improve quality of life.

Multimodal therapy for the treatment of sleep disturbance in patients with advanced cancer.

185 Background: Poor sleep quality is frequent in patients with advanced cancer (62%), and is associated with a severe symptom distress and mortality. There are limited evidence based treatment options in advanced cancer patients.To obtain feasibility, preliminary estimates of the effects of various treatments [light therapy, melatonin, Methylphenidate] and combinations of treatments in multimodal therapy (MMT) to improve sleep quality, as measured by change in Pittsburg Sleep Quality Index (PSQI) scores from baseline to Day 15. We also examined MMT effects on FACT-G, insomnia - Insomnia severity index (ISI), actigraphy. Methods: Cancer patients with moderate sleep disturbance were eligible. Using a double-blind (patient, investigators) randomized factorial study design, eligible Pts were randomized into 1 of the 8 arms of the study which included all possible combinations of the interventions (light therapy, melatonin, and methylphenidate) and/or their corresponding placebo treatments for a duration of 2 weeks. All patients received 3 sessions of standardized CBT. Linear regression analysis was used to assess treatment effects. Results: 84% (54/ 64) randomized Pts were evaluable. At baseline, median (IQR) total PSQI was 13 (12, 15); and ISI was 18 (14, 21). There were no differences in the demographics and baseline sleep quality between groups. The adherence rates for light therapy, melatonin, and methylphenidate were 93%, 100%, and 100% respectively. Light therapy had moderate effects on sleep quality (effect size .43, P=0.017). No significant differences in ISI, FACT-G scores, and objective sleep variables between groups. There were no significant difference in adverse events by groups (P=.97). Conclusions: MMT interventions to treat sleep disturbance were feasible. Light therapy provided the best signal for improvement in sleep quality, and should proceed to large randomized control trials. Clinical trial information: NCT0168029. [Table: see text]

Akne Vulgarisli Hastalarda İzotretinoin Tedavisinin Uyku ve Yaşam Kalitesine Etkisi

Objective: We aimed to investigate the effect of isotretinoin treatment on sleep and quality of life in patients with AV. Methods: Sixty-six AV patients, who had attended the dermatology outpatient clinic and started isotretinoin treatment, and forty-three healthy controls, were enrolled in the study. Pittsburg Sleep Quality Index (PSQI), short form-36 (SF-36), and Global Acne Grading System (GAGS) were administered to all patients twice; before and two months after the treatment. The results were compared with the healthy control group. Results: The pretreatment physical health scores of the patients were significantly higher than the healthy controls. No significant differences were observed between before-after isotretinoin treatment regarding physical and mental health scores in AV patients. While there were no significant differences between the pretreatment and healthy control group in terms of total PSQI scores; the scores of sleep duration were significantly lower in the pretreatment group. No significant differences were observed between before-after isotretinoin treatment regarding total PSQI and subcomponent scores in AV patients. There was a statistically significant negative correlation between pre- and post-treatment total PSQI scores and physical, mental health scores in patients with AV. Conclusion: Results of the present study suggest that isotretinoin therapy does not affect the sleep quality in patients with AV. The impairment of sleep quality negatively affects the quality of life in patients with AV. More comprehensive studies assessing the effect of isotretinoin treatment on sleep quality are needed.

Decreased serum vitamin B12 and vitamin D levels affect sleep quality in children with familial Mediterranean fever.

Familial Mediterranean fever is an autoinflammatory disorder characterized by recurrent fever and serositis. We aimed to describe serum vitamin B12 and vitamin D levels and their correlation with self-reported sleep quality of pediatric FMF patients. Sixty-three children with FMF were enrolled to the study. Information on sleep quality was obtained using self-administration of Pittsburg Sleep Quality Index (PSQI). The patients were divided into subgroups depending on vitamin D serum concentrations: ≥ 20 and < 20ng/ml. We also grouped patients according to their serum B12 concentration: ≥ 200, < 200pg/ml. B12 levels were not correlated with PSQI scores, whereas significant correlation was found between vitamin D and total PSQI scores and daytime sleepiness. Total PSQI score, sleep disorders and daytime sleepiness sub-scores were statistically high in patients with serum D vitamin levels below 20ng/ml. Sleep efficiency was found lower in patients with serum B12 levels below 200pg/ml. B12 may have a positive role on effective sleep. More importantly, we suggest that vitamin D is protective against sleep disorders and poor sleep, it may also improve daytime activities.

Repletion of vitamin D associated with deterioration of sleep quality among postmenopausal women

Reduced health-related quality of life (HRQOL), depressive symptoms and poor sleep quality are important health issues among postmenopausal women and may be associated with low vitamin D status. Overweight postmenopausal women, with serum 25-hydroxyvitamin D [25(OH)D] 10–32ng/m, were recruited in Seattle, WA (2010−2012) and randomly assigned to 12months of weight loss +2000IU oral vitamin D3/day or weight loss+daily placebo. The weight-loss program included a reduced-calorie diet and 225min/week of moderate-to-vigorous aerobic activity. Eight subscales of HRQOL were assessed by the MOS 36-Item Short-Form Health Survey. Depressive symptoms were assessed using the Brief Symptom Inventory-18, and sleep quality was assessed using the Pittsburg Sleep Quality Index (PSQI). Mean 12-month changes in HRQOL, depressive symptoms and sleep quality were compared between groups (intent-to-treat) using generalized estimating equations. Compared to placebo, women receiving vitamin D did not experience any significant change in depressive symptoms (p=0.78), HRQOL subscales (all p>0.05), or overall sleep quality (p=0.21). However, a greater magnitude of change in serum 25(OH)D was associated with an increased need to take medications to sleep (ptrend=0.01) and overall worse sleep quality (ptrend<0.01). Women who became vitamin D replete (≥32ng/mL) also showed a deterioration in total PSQI sleep quality score compared to women who remained <32ng/mL despite supplementation, even after adjusting for relevant covariates (Non-Replete: −5.7% vs. Replete: +6.2%, p<0.01). Vitamin D supplementation of 2000IU/d may result in overall worse sleep quality for postmenopausal women with low circulating vitamin D undergoing weight loss.

Evaluation of Sleep Disorders in Wartime Chemically Injured Veterans with Sleep-Related Complaints: Self-Report vs. Polysomnographic Measures

&lt;p&gt;&lt;strong&gt;BACKGROUND:&lt;/strong&gt; Sleep disorders are among the most common problems experienced by chemically injured veterans, affecting their quality of life and their general health. Therefore, we aimed to compare Polysomnography indices with data derived from the PSQI in chemically injured veterans in Iran in order to study the relationship between or independence of subjective complaints (self-reports) and objective data.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;METHODS:&lt;/strong&gt; In this study, 70 veterans were selected among chemically injured veterans who had referred to our clinic during 2012-2013 using the convenience sampling method. Objective and subjective sleep qualities were measured using the in-laboratory diagnostic Polysomnography method and the Pittsburg Sleep Quality Index (PSQI), respectively. The two measured were then compared.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;RESULTS:&lt;/strong&gt; All the 70 assessed veterans in this study were male with a mean±SD age of 50.2±9.97. The mean±SD total score for the PSQI was 12.38±4.34. We found no significant relationship between the total PSQI score and age (r=-0.045, P=0.80), marital status (r=0.14, P=0.437), and occupational status (r=0.242, P=0.175). However, a negative significant relationship was found between the total PSQI score and educational status (r=-0.464, P=0.007). Moreover, we found a significant relationship between sleep quality according to Polysomnography and age (r=0.254, P=0.039). However, no such relationship was found with respect to marital status (r=0.2, P=0.1), occupational status (r=0.02, P=0.863), and educational status (r=0.047, P=0.71). We found no significant relationship between any of the parameters measured by Polysomnography with the scores obtained in the 7 subscales of the PSQI or its total score.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;CONCLUSION:&lt;/strong&gt; An individual’s dissatisfaction with sleep quality does not necessarily indicate an objective sleep disorder. Objective evaluations alongside reports provided by friends and relatives play a key role in the correct diagnosis of sleep disorders in chemically injured veterans.&lt;/p&gt;

Noninvasive ventilation in amyotrophic lateral sclerosis: effects on sleep quality and quality of life

Objectives: Little is known about the effects of noninvasive ventilation (NIV) on sleep quality in amyotrophic lateral sclerosis (ALS). We aim to evaluate the long-term effects of NIV on sleep quality and quality of life in patients with ALS.Methods: In this prospective observational study, 13 ALS patients were followed for one year after initiating NIV. We evaluated sleep quality, quality of life and functional status with several questionnaires: Epworth sleepiness Scale (ESS), Pittsburg sleep quality index (PSQI), Short Form 36 Health Questionnaire (SF-36), McGill Quality of Life questionnaire (McGillQoL) and revised Amyotrophic Lateral Sclerosis Functional Rating Scale scores (ALSFRS-R).Results: Median and interquartile range (IQR) at the start of NIV was 59 (53–65) years. The ALSFRS-R at start was 30 (24–37) (median, IQR), with three patients having severe bulbar impairment (ALSFRS-R-bulbar ≤ 9). The PaCO2 at start of NIV treatment was 48 (43–52) mmHg (median, IQR). During the one-year follow-up period, a significant decrease in the ALSFRS-R was observed. The impact of NIV in a short term (1 month) revealed a statistically significant decrease in ESS, decrease in total PSQI and of four PSQI subscales and improvement of almost all subscales of the McGill questionnaire. Long-term analyses (9 months to 1 year) revealed that amelioration in ESS and total PSQI was sustained.Conclusion: We conclude that accurately titrated NIV in ALS patients can stabilize sleep quality and quality of life for at least one year, despite significant disease progression.

Laparoscopic Sleeve Gastrectomy Improves Excessive Daytime Sleepiness and Sleep Quality 6Months Following Surgery: A Prospective Cohort Study.

IntroductionObstructive sleep apnea (OSA) is one of the most important co-morbid conditions related with morbid obesity. Bariatric procedures are associated with significant improvement in OSA. The aim of the current study was to evaluate the effect of bariatric surgery on daytime sleepiness and quality of sleep in patients that had undergone laparoscopic sleeve gastrectomy.MethodsFifty-nine patients were prospectively enrolled in the study. Pre-operative and post-operative (6 months) demographics, medical history, weight, and height of the patients were recorded, and patients were asked to complete Pittsburg Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS) questionnaires. OSA screenings were performed using the STOP-Bang questionnaire.ResultsThe mean age of the patients was 37.1 ± 1.2 years and 76% were female. Pre-operative and post-operative median (range) BMIs were 47 kg/m2 (39–67 kg/m2) and 35 kg/m2 (25–44 kg/m2), respectively (P < 0.001). The mean ± standard deviation excess weight loss was 51.6 ± 13.2%. In univariate analysis, total PSQI, STOP-Bang, and ESS scores were found to significantly improve 6 months after surgery (all P < 0.001). Multivariate mixed-model analysis showed a high correlation between the decrease in BMI and all key predictors. Mixed-model analysis revealed that every 1 kg/m2 decrease in BMI was associated with a 0.32, 0.13, and 0.26 improvements in PSQI, STOP-Bang, and ESS scores, respectively (all P < 0.001).ConclusionLaparoscopic sleeve gastrectomy is associated with rapid weight loss and improvements in sleep quality, daytime sleepiness, and the risk of OSA 6 months after surgery.

Prevalence and associated factors of hypnotics dependence among Japanese outpatients with psychiatric disorders

This study aimed to investigate the prevalence of the dependence for benzodiazepine or their agonist (BZDs) hypnotics, as well as factors associated with this dependence among Japanese psychiatric outpatients. One thousand and forty-three patients in the psychiatric outpatient clinic of Tokyo Medical University Hospital receiving treatment with BZDs hypnotics were analyzed. The subjects answered questionnaires including demographic variables, subjective sleep difficulty assessed by the Pittsburg Sleep Quality Index (PSQI), duration of hypnotics medication, dose of diazepam equivalent BZDs hypnotics, the presence or absence of subjective side effects due to BZDs hypnotics (dizziness, fatigue, daytime sleepiness, amnesia, and headache), and dependency assessed by the Dependency 2-A (D 2-A) score. Subjects with a D 2-A score ≥10 were considered as having BZDs hypnotics dependence, and the variables associated with the presence of dependence were examined using logistic regression analyses. Eighty-two out of the 1043 subjects (7.9%) were determined to have BZDs hypnotics dependence. Compared with the non-dependence group, the dependence group had a significantly higher proportion of positive respondents for all the side effects. Multiple logistic regression analyses showed that the dependence was significantly associated with younger age, higher total PSQI score, and higher daily dose of BZDs hypnotics. Younger age, higher total PSQI score, and higher dose may be associated with BZDs hypnotics dependence. The finding that patients with BZDs hypnotics dependence frequently suffered from subjective side effects and had greater sleep difficulty encourages the establishment of alternative treatments for patients with insomnia symptoms refractory to BZDs hypnotics treatment.

AB0903 Sleep quality and associated factors in ankylosing spondylitis: Relation with disease parameters, psychological status and quality of life

BackgroundDisturbance in sleep quality is important problem in ankylosing spondylitis(AS). Sleep problems may be affected from different aspects.ObjectivesWe aimed to investigate sleep quality and its association with the disease specific...