Total Mass Research Articles

Association between insulin sensitivity and lean mass loss during weight loss.

The study objective was to assess the relationship between insulin sensitivity and changes in total lean mass (LM) and appendicular LM (ALM) during weight loss. Individuals were randomly assigned to either a standard or a moderately reduced carbohydrate diet for 16 weeks. Body composition was assessed using dual-energy x-ray absorptiometry and insulin sensitivity index (SI) using an intravenous glucose tolerance test. Multiple linear regression was used to determine whether baseline SI was predictive of changes in total LM and ALM. Participants (n = 57; baseline BMI 32.1 ± 3.8 kg/m2) lost an average of 6.8 ± 3.2 kg of body weight (p < 0.001), with 1.5 ± 2.6 kg coming from LM (p < 0.05) and 0.5 ± 0.73 kg from ALM (p < 0.05). Multiple regression analysis demonstrated that SI was inversely associated with changes in total LM (kilograms; β = 0.481, p < 0.001), after adjusting for baseline LM, fat mass, acute insulin response to glucose, and weight loss. Similar results were seen when assessing ALM loss (β = 0.359, p < 0.05). Identifying individuals with low insulin sensitivity prior to weight loss interventions may allow for a personalized approach aiming at minimizing LM loss.

Pigmentos fotossintéticos, crescimento, e produção de tomate cereja sob estresse salino e peróxido de hidrogênio

ABSTRACT Excess of salts in water and/or soil stands out as one of the stresses that compromise the development of crops, including cherry tomato, requiring the use of strategies that reduce salt stress effects, such as foliar application of hydrogen peroxide. Thus, the objective of this study was to evaluate the effect of foliar application of H2O2 on the contents of photosynthetic pigments, growth, and production of cherry tomato under irrigation water salinity. The design used was randomized blocks, in a 5 × 5 factorial scheme, with five values of electrical conductivity of water - ECw (0.3, 1.0, 1.7, 2.4, and 3.1 dS m-1) and five concentrations of hydrogen peroxide - H2O2 (0, 15, 30, 45, and 60 μM). Application of hydrogen peroxide at concentration of 60 μM attenuated the deleterious effects of salt stress on the growth and number of leaves of cherry tomato up to ECw of 3.1 dS m-1. Hydrogen peroxide concentration of 45 μM increased root dry mass, synthesis of chlorophyll b and total chlorophyll under electrical conductivity of water of 0.3 dS m-1 and synthesis of chlorophyll a up to ECw of 0.8 dS m-1. Foliar application of 30 μM reduced the effects of salt stress on leaf, shoot and total dry mass accumulation up to ECw of 3.1 dS m-1. Electrical conductivity of water from 1.41 dS m-1 reduced the production of cherry tomato.

An Effective Approach to Enhance the Dissolution Profile of Curcumin and Quercetin: Liquisolid Compacts

Background: The drugs categorized under BCS class II and IV are poorly water-soluble, which in turn affects their dissolution and bioavailability. To overcome these limitations, namely, poor solubility and bioavailability, several approaches have been tried so far, like, co-solvency, size reduction or micronization, complexation, adsorption on high surface area carriers, etc. Objective: The present article aims to explore the utilization of the liquisolid technique to improve the dissolution profile of curcumin and quercetin, used as a combination in a solid dosage form. It covers the study of the impact of various carriers employed in liquisolid technology on drug dissolution profiles; Avicel pH 101, Fujicalin and Neusilin were used as carriers in this study. Methods: The solubility of the drugs was evaluated in various non-volatile solvents except water to select the vehicle having maximum solubility. All formulations were then prepared using curcumin and quercetin in a ratio of 2:1 (150 mg curcumin : 75 mg Quercetin), comprising a proportion of 40-60% w/w of the total mass of the formulation and were estimated for post-compression parameters. During the final processing of the liquisolid compacts, the carrier is to coating material ratio was kept consistent, i.e., 20:1. Results: Powder X-ray Diffraction (PXRD) and Fourier Transform Infrared Spectroscopy (FTIR) were utilized to analyze drug-excipient interaction; these studies stated no evidence of any physical or chemical interaction between drug(s) and the excipients. The final product was then evaluated for the liquid adsorption capacity and in vitro release of the drugs as a combination, and it was observed that these two properties were found to be significantly improved in the liquisolid compacts. Conclusion: The outcomes indicated that the combination of Neusilin as the carrier and castor oil as a non-volatile solvent was the best-performing formulation appropriate for targeting an improved dissolution profile.

Fluid and electrolyte balance following consumption of skimmed milk and a plant-based soya beverage at rest in euhydrated males.

Cow's milk is one of the most hydrating beverages, but many individuals choose not to consume dairy in their diet due to intolerance, allergy, or dietary preference. Milk is commonly replaced with plant-based beverages, including soya which has the most comparable protein content, but little is known about their hydration potential. This study compared fluid and electrolyte balance responses between a soya beverage and skimmed cow's milk. Ten healthy males [age 27 (6) y; body mass index 24.6 (2.3) kg/m2] completed two randomised counterbalanced trials, involving consuming 1000mL water from approximately isocaloric amounts of skimmed cow's milk (MILK) or a sweetened soya beverage (SOYA), in four aliquots over 30min in a euhydrated fasted state. Volume, specific gravity, and electrolyte (sodium, potassium, chloride) concentrations were determined in total-void urine samples collected pre-/post-beverage ingestion, and hourly for 180min thereafter. Hunger, thirst, nausea and stomach fullness were rated proximal to urine samples. Total urine mass (MILK, 986 ± 254g; SOYA, 950 ± 248g; P = 0.435) and urine specific gravity (P = 0.156) did not differ between trials. Potassium balance was greater in SOYA 0-180min post-beverage (P ≤ 0.013), whilst chloride balance was greater in MILK 0-120min post-beverage (P ≤ 0.036). Sodium balance (P = 0.258), total electrolyte balance (P = 0.258), and subjective measures (P ≥ 0.139) were not different between trials. Replacing cow's milk with a soya beverage did not negatively impact fluid balance in healthy young males, making it a viable option for those who choose not to consume dairy in their diet.

Radiative and mechanical energies in galaxies. I. Contributions of molecular shocks and PDRs in 3C 326 N

Atomic and molecular lines emitted from galaxies are fundamental tracers of the medium responsible for the emission and contain valuable information regarding the energy budget and the strength of the different feedback mechanisms. The goal of this work is to provide a new framework for the interpretation of atomic and molecular lines originating from extragalactic sources and a robust method to deduce the mechanical and radiative energy budget from a set of observations. Atomic and molecular lines detected in a given object are assumed to result from the combination of distributions of shocks and photo-dissociation regions (PDRs) within the observational beam. The emission of individual structures is computed using the Paris-Durham shock code and the Meudon PDR code over a wide range of parameters. The total emission is then calculated assuming probability distribution functions for shocks and PDRs. A distance between the observational dataset and the model is finally defined based on the ratios of the observed to the predicted intensities. As a test case scenario, we consider the radio galaxy 3C 326 N. The dataset is composed of 12 rotational and ro-vibrational lines of and the fine structure lines of C$^+$ and O. Our interpretative framework shows that both shocks and PDRs are required to explain the line fluxes. Surprisingly, viable solutions are obtained at low density only ($ n_H &lt; 100 $), indicating that most of the emission originates from diffuse interstellar matter. The optimal solution, obtained for $ n_H = 10 $, corresponds to a distribution of low-velocity shocks (between $5$ and $20$ km s$^ $) propagating in PDR environments illuminated by a UV radiation field ten times larger than that in the solar neighborhood. This solution implies that at least 4&lt;!PCT!&gt; of the total mass carried by the PDRs is shocked. The 0-0 S(0) $28 CII and OI lines originate from the PDR components, while all the other lines are mostly emitted by shocks. The total solid angles sustained by PDRs and shocks imply that the radiative and mechanical energies reprocessed by these structures are $ L UV L_ odot $ and $ L K L_ odot $, respectively, in remarkable agreement with the values of the IR luminosity deduced from the fit of the spectral energy distribution (SED) of 3C 326 N, and consistent with a small fraction of the active galactic nuclei (AGN) jet kinetic power dissipated in the interstellar medium ($ 1$&lt;!PCT!&gt;). This work shows that the radiative and mechanical energy budget of galaxies can be derived from the sole observations of atomic and molecular lines. It reveals the unexpected importance of the diffuse medium for 3C 326 N, in contrast to previous studies. A last-minute comparison of the model to new JWST data obtained in 3C 326 N shows a striking agreement and demonstrates the ability of the model to make accurate predictions. This framework opens new prospects for the prediction and interpretation of extragalactic observations, in particular in the context of JWST observations.

Plasma Mitochondrial DNA Clearance by Continuous Venovenous Haemofiltration in Critically Ill Patients

Abstract Objective Mitochondrial DNA (mtDNA) reportedly has diagnostic and predictive value in critically ill patients. This study evaluated the diagnostic and predictive value of mtDNA in patients undergoing continuous venovenous haemofiltration (CVVH). Methods We consecutively enrolled 41 patients who were treated with CVVH from September 2018 to December 2019. Prefilter, postfilter, and ultrafiltrate samples were collected before the initiation of CVVH (T0) and 6 and 12 h after CVVH. The total mass removal rate (Mtr), total mass adsorption rate (Mad), plasma clearance (PC), and sieving coefficient (SC) were calculated based on the mass conservation principle. Results The plasma mtDNA concentration in patients at T0 prefilter was higher than that in healthy volunteers [13.77 (12.45–15.86) vs. 1.24 (1.15–1.34) ng/mL, P &lt; 0.001]. Prefilter, but not postfilter or ultrafiltrate, mtDNA decreased during CVVH (P = 0.02), with a total CVVH clearance of 25.9%. The postfilter and ultrafiltrate mtDNA levels were lower than the prefilter level at each time point (P &lt; 0.05 for all). The Mtr, Mad, PC, and SC did not change over time (P &gt; 0.05 for all). Conclusions Plasma mtDNA in critically ill patients was significantly affected by CVVH. Trial registration: Retrospectively registered on 20 August 2019 at ClinicalTrials.gov (NCT04083482).

A Full Accounting of the Visible Mass in SDSS MaNGA Disk Galaxies

We present a study of the ratio of visible mass to total mass in spiral galaxies to better understand the relative amount of dark matter present in galaxies of different masses and evolutionary stages. Using the velocities of the Hα emission line measured in spectroscopic observations from the Sloan Digital Sky Survey (SDSS) MaNGA Data Release 17 (DR 17), we evaluate the rotational velocity of over 5500 disk galaxies at their 90% elliptical Petrosian radii, R 90. We compare this to the velocity expected from the total visible mass, which we compute from the stellar, H i, H2, and heavy metals and dust masses. H2 mass measurements are available for only a small subset of galaxies observed in SDSS MaNGA DR17, so we derive a parameterization of the H2 mass as a function of absolute magnitude in the r band using galaxies observed as part of SDSS DR7. With these parameterizations, we calculate the fraction of visible mass within R 90 that corresponds to the observed velocity. Based on statistically analyzing the likelihood of this fraction, we conclude that the null hypothesis (no dark matter) cannot be excluded at a confidence level better than 95% within the visible extent of the disk galaxies. We also find that when all mass components are included, the ratio of visible to total mass within the visible extent of star-forming disk galaxies increases with galaxy luminosity.

Elevational variation in morphology and biomass allocation in carpathian snowbell Soldanella carpatica (Primulaceae)

Plants growing along wide elevation gradients in mountains experience considerable variations in environmental factors that vary across elevations. The most pronounced elevational changes are in climate conditions with characteristic decrease in air temperature with an increase in elevation. Studying intraspecific elevational variations in plant morphological traits and biomass allocation gives opportunity to understand how plants adapted to steep environmental gradients that change with elevation and how they may respond to climate changes related to global warming. In this study, phenotypic variation of an alpine plant Soldanella carpatica Vierh. (Primulaceae) was investigated on 40 sites distributed continuously across a 1,480-m elevation gradient in the Tatra Mountains, Central Europe. Mixed-effects models, by which plant traits were fitted to elevation, revealed that on most part of the gradient total leaf mass, leaf size and scape height decreased gradually with an increase in elevation, whereas dry mass investment in roots and flowers as well as individual flower mass did not vary with elevation. Unexpectedly, in the uppermost part of the elevation gradient overall plant size, including both below-and aboveground plant parts, decreased rapidly causing abrupt plant miniaturization. Despite the plant miniaturization at the highest elevations, biomass partitioning traits changed gradually across the entire species elevation range, namely, the leaf mass fraction decreased continuously, whereas the flower mass fraction and the root:shoot ratio increased steadily from the lowest to the highest elevations. Observed variations in S. carpatica phenotypes are seen as structural adjustments to environmental changes across elevations that increase chances of plant survival and reproduction at different elevations. Moreover, results of the present study agreed with the observations that populations of species from the ‘Soldanella’ intrageneric group adapted to alpine and subnival zones still maintain typical ‘Soldanella’-like appearance, despite considerable reduction in overall plant size.

Elevated nitrogen and co-evolution history with competitors shape the invasion process of Galinsoga quadriradiata

Abstract Invasive plants usually experience population differentiation as they expand from their initial invasive range to the edge. Moreover, invasive plants usually encounter competitors which shared different co-evolutionary histories with them. These factors may lead to varying responses of invasive plant populations to elevated nitrogen deposition during expansion. However, this issue has received limited attention in prior research. To address these challenges, we conducted a greenhouse experiment to investigate how population differentiation of Galinsoga quadriradiata interacts with the presence of various competitors in response to increased nitrogen deposition. Competitor types (new or old that shared short or long co-evolutionary history with the invader, respectively) were set to compete with the invasive central and edge populations under different nitrogen addition treatments. Individuals from the central population of G. quadriradiata, originating from the initial invasion range, showed greater total mass, reproduction, and interspecific competitiveness compared to the edge population. Nitrogen addition improved growth and reproductive performance in both populations, and the central population had a stronger response compared to the edge population. The performance of G. quadriradiata was inhibited more effectively by old competitors than new competitors. Our results indicate that population differentiation occurs in terms of growth and competitiveness during the range expansion of G. quadriradiata, with the central population exhibiting superior performance. Co-evolutionary history with competitors is considered unfavorable for invasive plants in this study. Our results highlight the combined effects of population differentiation in invasive species and their co-evolution history with competitors in the context of global change factors.

The 23–24 March 2021 lava fountain at Mt Etna, Italy

In 2021, more than 50 paroxysmal episodes occurred at the South-East Crater (SEC) of Mt Etna, Italy. The 23–24 March lava fountain was one of the longest episodes and began with weak Strombolian explosions, gradually transitioning to lava fountaining. The eruption intensity then dropped more slowly than in previous episodes, resulting in pulsating Strombolian explosions dominated by ash emission. Thirty-four tephra samples were used to reconstruct the fallout dispersal and estimate the total erupted mass. Grain size, textural, petrological and geochemical analyses indicate different features and were compared with the gas phase (SO2 and HCl) in the volcanic plume. By applying stochastic global optimization to simulations of the temporal evolution of the eruption column height and tephra dispersal and deposition, the total erupted mass retrieved (6.76 × 108 kg) matches well the total erupted mass estimation by the ground-based deposit (8.03 ± 2.38 × 108 kg), reducing the column height throughout the episode from 6.44 to 4.5 km above sea level and resulting in a mass eruption rate ranging from 1.96 × 105 to 8.18 × 103 kg/s. The unusual duration of the March episode and the characteristics of the erupted products point to the change in explosive style and magma fragmentation from fountaining to ash emission phases, associated with a slower magma supply inducing a change in magma rheology and a final, prolonged ash generation. Furthermore, this study showed that using observational data and the variation in eruption source parameters for numerical simulations can improve the accuracy of predicting the dispersal plume, thus mitigating the potential impact of longer paroxysmal episodes.

The powerful lens galaxy cluster PLCK G287.0+32.9 (θE ∼ 43″)

Aims. We present a new high-precision strong-lensing model of PLCK G287.0+32.9, a massive lens galaxy cluster at z = 0.383, with the aim of obtaining an accurate estimation of its effective Einstein radius and total mass distribution. We also present a spectroscopic catalog containing accurate redshift measurements for close to 500 objects up to redshift z = 6, including multiply lensed sources and cluster member galaxies. Methods. We exploited high-quality spectroscopic data from the Multi Unit Spectroscopic Explorer (MUSE), covering a central 3 arcmin2 region of the cluster. We supplemented the spectroscopic catalog by including redshift measurements from VIsible MultiObject Spectrograph (VIMOS) and DEep Imaging Multi-Object Spectrograph (DEIMOS). We identified 129 spectroscopic cluster member galaxies with redshift values of 0.360 ≤ z ≤ 0.405, and mF160W ≤ 21. We complemented this galaxy cluster member sample with 24 photometric members identified with a convolutional neural network (CNN) approach. We also identified 114 multiple images from 28 background sources, of which 84 images from 16 sources are new and the remaining ones have already been identified in previous works. From these, we extracted “golden sample” of 47 secure multiple images and used them, together with the selected cluster member, to build and optimize several strong-lensing models with the software lenstool. Results. The best-fitting lens model shows a root mean square (RMS) separation value between the predicted and observed positions of the multiple images of 0.″75. Using its predictive power, we found three new multiple images and we confirm the configuration of three systems of multiple images that were not used for the optimization of the model. For a source at a redshift of zs = 2, we found a cluster with an Einstein radius of θE = 43.4″ ± 0.1″. This value is in agreement with previous estimates and corresponds to a total mass enclosed in the critical curve of ME = 3.33−0.07+0.02 × 1014 M⊙. Conclusions. The combined application of ancillary Hubble Space Telescope (HST) imaging, VIMOS and DEIMOS data, and the new MUSE spectroscopic observations allowed us to build a new lens model of the galaxy cluster PLCK G287.0+32.9, with an improvement in terms of reconstructing the observed positions of the multiple images of a factor of 2.5 with respect to previous models. The derived total mass distribution confirms this cluster to be a very prominent gravitational lens, with an effective Einstein radius of θE ∼ 43″. We were also able to construct an extensive spectroscopic catalog containing 490 objects, of which 153 are bright cluster members with mF160W ≤ 21, and 114 are multiple images.

TOI-837 b is a young Saturn-sized exoplanet with a massive 70 M⊕ core

Abstract We present an exhaustive photometric and spectroscopic analysis of TOI-837, a F9/G0 35 Myr young star, hosting a transiting exoplanet, TOI-837 b, with an orbital period of ∼8.32 d. Utilising data from TESS and ground-based observations, we determine a planetary radius of $0.818_{-0.024}^{+0.034}$ RJ for TOI-837 b. Through detailed HARPS spectroscopic time series analysis, we derive a Doppler semi-amplitude of $34.7_{-5.6}^{+5.3}$ m s−1 , corresponding to a planetary mass of $0.379_{-0.061}^{+0.058}$ MJ . The derived planetary properties suggest a substantial core of approximately 70 M⊕, constituting about 60% of the planet’s total mass. This finding poses a significant challenge to existing theoretical models of core formation. We propose that future atmospheric observations with JWST could provide insights into resolving ambiguities of TOI-837 b, offering new perspectives on its composition, formation, and evolution.

Design, Construction, and Flight Performance of an Electrically Operated Fixed-Wing UAV

The development of unmanned aerial vehicles (UAVs) has attracted much attention in the global community and aviation industry. As UAVs have the potential to be applied for multiple missions, the level of research into improving their design and flight performance has also increased. In this context, the present paper aims to present the design, construction, and flight performance of an electrically operated fixed-wing UAV. As a first step in the design process, key performance requirements are defined, such as the thrust required, the stall speed, the minimum drag velocity, and the minimum power velocity. Wing and associated power loadings are calculated according to the defined performance requirements. In addition, payload and endurance requirements are set up in order to determine the wing and tail areas, the total mass, the power requirements, and the motor size. Aerodynamics and stability designs are also calculated. After the completion of the design process, the manufacturing of the UAV follows by using appropriate materials. Flight tests were carried out for the evaluation of the UAV’s flight performance, where the success of the design was demonstrated.

Effects of late gestational nutrient restriction on uterine artery blood flow, placental size, and cotyledonary mRNA expression in primiparous beef females.

Fall-calving primiparous beef females [body weight (BW): 451 ± 28 (SD) kg; body condition score (BCS): 5.4 ± 0.7] were individually-fed either 100% (control; CON; n = 13) or 70% (nutrient restricted; NR; n = 13) of metabolizable energy and metabolizable protein requirements for maintenance, pregnancy, and growth from day 160 of gestation to parturition. Doppler ultrasonography of both uterine arteries was conducted pre-treatment and every 21 d from days 181 to 265 of gestation. Expelled placentas were collected, and ipsilateral cotyledonary tissue was sampled to assess relative messenger ribonucleic acid (mRNA) expression. Placentas were separated into ipsilateral and contralateral sides, dissected (cotyledonary vs. intercotyledonary), and dried. Data were analyzed with nutritional plane, treatment initiation date, and calf sex (when P < 0.25) as fixed effects. Uterine blood flow included day and nutritional plane × day as repeated measures. We previously reported that post-calving, NR dams weighed 64kg less and were 2.0 BCS lower than CON, but calf birth weight was not affected. Maternal heart rate was less (P < 0.001) for NR dams than CON after nutritional planes began. Nutritional plane did not affect (P ≥ 0.20) uterine artery hemodynamics, but all variables were affected (P ≤ 0.04) by day. Contralateral cotyledonary and placental weight were less (P ≤ 0.04) and contralateral intercotyledonary weight and number of cotyledons tended to be less (P ≤ 0.10) for NR dams than CON, but ipsilateral and whole placental weights were not affected (P ≥ 0.13). Ipsilateral placental weight as a percentage of total placental weight was greater (P = 0.03) for NR dams than CON. Whole placental cotyledonary:intercotyledonary weight was less (P = 0.01) for NR dams than CON. Placental efficiency was not affected (P = 0.89) by nutritional plane. Cotyledonary relative mRNA expression of GLUT3 and SNAT2 was greater (P ≤ 0.05) and relative expression of GLUT1, GLUT4, and NOS3 tended to be greater (P ≤ 0.07) for NR dams than CON. Nutritional plane did not affect (P ≥ 0.13) relative mRNA expression of GLUT5, 4F2hc, CAT1, LAT1, LAT2, VEGFA, FLT1, KDR, GUCY1B3, and PAG2. Despite less contralateral placental growth, beef heifers experiencing late gestational nutrient restriction maintained uterine artery blood flow and total placental mass and had 4 nutrient transporters and 1 angiogenic factor upregulated in cotyledons, all which likely contributed to conserving fetal growth.

Associations of fat and muscle mass indices with incident atrial fibrillation: data of PREVEND

Abstract Background Whether the association between body mass and atrial fibrillation (AF) risk is driven by fat mass or muscle mass remains unclear. Objective To examine the association of relative fat mass (RFM, a novel marker of whole-body fat percentage) and 24-hour urinary creatinine excretion (a marker of total muscle mass) with incident AF. Participants: We included 8120 community-dwelling adults from the PREVEND cohort without prevalent AF. Results The mean age of the population was 49.8±12.6 years and 50.0% (n=4060) were women. The mean RFM was 30.2±7.4 % and the mean creatinine excretion was 12.3±3.5 mmol/24h. During a mean follow-up period of 9.7±2.4 years, 261 AF events (3.2%) occurred. We included RFM, creatinine excretion, age, sex, height, heart rate, hypertension and cardiovascular disease history in a multivariable Cox regression model. The association between RFM and AF risk was linear, and the hazard ratio per 1 SD increase in RFM was 1.40; 95%CI: 1.17-1.66 (P&amp;lt;0.001). The association between creatinine excretion and AF risk was non-linear (P-value quadratic trend=0.006): compared with individuals in tertile 2 of creatinine excretion, those in tertile 1 had a HR of 1.70; 95%CI: 1.21-2.29 (P=0.002) and those in tertile 3 also had a HR of 1.74; 95%CI: 1.22-2.47 (P=0.002). Conclusion In the general population, both fat mass and muscle mass are associated with incident AF. While obesity should be considered as a major risk factor for AF, increased AF risk in individuals with low and high muscle mass warrants further investigation.

Planet Formation by Gas-assisted Accretion of Small Solids

We compute the accretion efficiency of small solids, with radii 1 cm ≤ R s ≤ 10 m, on planets embedded in gaseous disks. Planets have masses 3 ≤ M p ≤ 20 Earth masses (M ⊕) and orbit within 10 au of a solar mass star. Disk thermodynamics is modeled via 3D radiation-hydrodynamics calculations that typically resolve the planetary envelopes. Both icy and rocky solids are considered, explicitly modeling their thermodynamic evolution. The maximum efficiencies of 1 ≤ R s ≤ 100 cm particles are generally ≲10%, whereas 10 m solids tend to accrete efficiently or be segregated beyond the planet’s orbit. A simplified approach is applied to compute the accretion efficiency of small cores, with masses M p ≤ 1 M ⊕ and without envelopes, for which efficiencies are approximately proportional to Mp2/3 . The mass flux of solids, estimated from unperturbed drag-induced drift velocities, provides typical accretion rates dM p /dt ≲ 10−5 M ⊕ yr−1. In representative disk models with an initial gas-to-dust mass ratio of 70–100 and total mass of 0.05–0.06 M ⊙, the solids’ accretion falls below 10−6 M ⊕ yr−1 after 1–1.5 Myr. The derived accretion rates, as functions of time and planet mass, are applied to formation calculations that compute dust opacity self-consistently with the delivery of solids to the envelope. Assuming dust-to-solid coagulation times of ≈0.3 Myr and disk lifetimes of ≈3.5 Myr, heavy-element inventories in the range 3–7 M ⊕ require that ≈90–150 M ⊕ of solids cross the planet’s orbit. The formation calculations encompass a variety of outcomes, from planets a few times M ⊕, predominantly composed of heavy elements, to giant planets. The peak luminosities during the epoch of the solids’ accretion range from ≈10−7 to ≈10−6 L ⊙.

Differences and Relationship between Body Composition and Motor Coordination in Children Aged 6–7 Years

Background: The primary goal of this study was to investigate the relationship between body composition and motor coordination performance, and the secondary goal was to determine sex differences in body composition and motor coordination of preschool children. Methods: Forty-eight children (23 boys and 25 girls) underwent assessments for body composition and motor coordination using the Köperkoordinationstest für Kinder (KTK). Results: Linear regression analysis revealed significant associations between body composition and motor coordination in boys (p &lt; 0.05) but not in girls. In boys, Body height (p = 0.01), Total muscle mass (p = 0.03), Total fat (p = 0.03), and Total water (p = 0.02) show statistically significant influence on single-leg jumps. Similar results were obtained for lateral jumps where there was a statistically significant influence of Body height (p = 0.01), Total muscle mass (p = 0.03), and Total water (p = 0.02). Interestingly, predictive variables showed no statistically significant influence on KTK overall score in boys (p = 0.42) nor in girls (p = 0.90). Conclusions: The predictive system of morphological variables demonstrated significance only among boys in this age group and sample. Girls outperformed boys due to early maturation, resulting in better average KTK scores.

Production of Seedlings of Corymbia citriodora Inoculated with Endophytic Bacteria

This study aimed to evaluate the effect of inoculants of endophytic bacteria producing indoleacetic acid (IAA) on the physiological quality of seeds and the production of seedlings of Corymbia citriodora (Hook.) KD Hill &amp; LAS Johnson. In the physiological quality test of the seeds, the treatments used were individual inoculation with Priestia megaterium, Exiguobacterium sibiricum, Pantoea vagans strain 45URP4-1, and Bacillus sp.; joint effect of the four strains (mix); inoculation only with the carrier (cassava starch and activated charcoal); carrier with 1.0 μg mL−1 of IAA; and non-inoculated control without IAA and without a carrier. In the production of seedlings in a greenhouse, the treatments were the same, except for the mix, which was replaced by P. vagans strain 7URP1-6 (Pvs7), as inoculation with the mix increased the number of abnormal seedlings. In the physiological quality test of seeds, seeds inoculated with the bacteria individually did not have the physiological quality impaired and the carrier created a microenvironment around the seeds, benefiting germination percentage, germination speed index, average germination time, and average germination speed. In the greenhouse, seedlings inoculated with Pvs7, P. megaterium and E. sibiricum were taller, with a larger stem diameter and dry mass of shoot, roots, and total. Seeds inoculated with E. sibiricum had higher averages for height, chlorophyll b content, and shoot and total dry mass, as well as a greater ability to colonize the rhizosphere and roots of C. citriodora, resulting in the production of higher-quality seedlings. Inoculation of seeds of C. citriodora with endophytic bacteria proved to be a promising alternative for plant development.

Fermion-antifermion pairs in a magnetized space-time with non-zero cosmological constant

We analyze a fermion-antifermion pair within the (2+1)-dimensional Bonnor-Melvin magnetic (BMM) spacetime featuring a nonzero cosmological constant (Λ>0). To do this, we rigorously investigate analytical solutions to the corresponding form of a fully-covariant two-body Dirac equation. We derive a non-perturbative wave equation and obtain an exact closed-form analytical solution for the system under consideration. In this magnetic background spacetime, described by a surface with positive Gaussian curvature, we noticed that fermion-antifermion pairs display a collective behavior resembling that of a single quantum oscillator, carrying a total rest mass of the particles and oscillating with a frequency (ωo∝Λ), even in the absence of mutual interaction between the particles. This indicates a compelling correlation between the cosmological constant and the energy spectrum of fermion-antifermion systems, implying connections between quantum realms and cosmology.

#2418 Effects of correction of acidosis on body composition and biochemical parameters in CKD patients on maintenance hemodialysis

Abstract Background and Aims Metabolic acidosis is a common problem in patients of chronic kidney disease and patients on maintenance hemodialysis. In resource poor countries, due to financial constraints frequency of dialysis and compliance to medication is adversely affected. This leads to worsening of clinical condition of patient and requirement of in hospital care, many times intensive care, further increasing cost of treatment. Metabolic acidosis has implications on bone and muscle health. Aim of our study was to assess the changes in body composition (fat percentage and lean body mass), changes in third space fluid, biochemical parameters, number of admissions and requirement of blood transfusions before and after correction of metabolic acidosis. Method This was a prospective, observational study. 25 patients on maintenance hemodialysis at our center were included in the study. Bio-impedance analysis (BIA), biochemical parameters (Complete blood counts, renal function tests, serum calcium and phosphorous, liver function tests, Blood gas analysis) were done at baseline before starting bicarbonate supplementation. Number of admissions and blood transfusions in 3 months prior to initiation of bicarbonate supplementation were noted. The oral bicarbonate supplementation was increased from baseline, based on the baseline blood gas analysis. The same parameters were assessed after 3 months and analyzed. Results At the end of 3 months we observed that there was significant reduction (p &amp;lt; 0.05) in total leucocyte counts (mean 8100/cumm to 6800/cumm), urea (mean 113.7 mg/dL to 83.72 ng/dL), creatinine (mean 7.87 mg/dL to 6.68 mg/dL), phosphorous (mean 5.18 mg/dL to 4.43 mg/dL), SGOT (mean 56.52 IU to 25.2 IU) and SGPT (mean 46.48 IU to 22.88 IU) with a trend of decrease (p ≤ 0.1) in percentage of extra cellular water (27.31% to 25.03%), lean body mass (44.27 kg to 43.0 kg) and trend of increase (p ≤ 0.1) in body fat composition (15.62 kg to 18.82 kg) and body fat percentage (26.924% to 31.90). There was a reduction in third space fluid (0.88 lit to 0.43 lit). The number of hospitalizations reduced (15 three months prior to initiation of therapy to 7 after initiation of therapy) and number of blood transfusions required also reduced (21 before initiation to 10 after initiation of therapy). Conclusion We concluded that correction of acidosis probably reduces the inflammation in patients of CKD on maintenance hemodialysis. This could be seen from the reduced total leucocyte counts, liver enzymes, urea and creatinine values. Changes in body composition with increased total fat mass, fat percentage and decreased lean mass was also noted. There was also a significant reduction in hospitalizations and number of blood transfusions.