Clothes-Changing Person Re-Identification is a challenging problem in computer vision, primarily due to the appearance variations caused by clothing changes across different camera views. This poses significant challenges to traditional person re-identification techniques that rely on clothing features. These challenges include the inconsistency of clothing and the difficulty in learning reliable clothing-irrelevant local features. To address this issue, we propose a novel network architecture called the Attention-Enhanced Multimodal Feature Fusion Network (AE-Net). AE-Net effectively mitigates the impact of clothing changes on recognition accuracy by integrating RGB global features, grayscale image features, and clothing-irrelevant features obtained through semantic segmentation. Specifically, global features capture the overall appearance of the person; grayscale image features help eliminate the interference of color in recognition; and clothing-irrelevant features derived from semantic segmentation enforce the model to learn features independent of the person’s clothing. Additionally, we introduce a multi-scale fusion attention mechanism that further enhances the model’s ability to capture both detailed and global structures, thereby improving recognition accuracy and robustness. Extensive experimental results demonstrate that AE-Net outperforms several state-of-the-art methods on the PRCC and LTCC datasets, particularly in scenarios with significant clothing changes. On the PRCC and LTCC datasets, AE-Net achieves Top-1 accuracy rates of 60.4% and 42.9%, respectively.