In the early days of its emergence, the social work profession was seen as a social assistance profession. The profession, which has developed mostly in the focus of poverty, has started to benefit from the theories, approaches and models of different disciplines such as psychology and sociology and has an eclectic knowledge base. Social work, which evaluates human behavior, needs and problems with a biopsychosocial focus, continues to benefit from different disciplines. One of these disciplines is neuroscience, which facilitates our understanding of the brain's function and life-long processes. Studies showing the connection between social work and neuroscience are increasing, albeit slowly, around the world. This study aims to reveal the role of neuroscience in understanding the factors that affect the social behavior of individuals within the framework of the "person in environment" approach, which is one of the dominant paradigms in social work today.