Tissue Dimensional Changes Research Articles

Radiographic bone level and soft tissue dimensional changes following explantation of implants affected by peri-implantitis: A retrospective exploratory evaluation.

While the dimensional alteration of alveolar bone following tooth extraction have been extensively descripted in the literature, no information is available regarding potential hard and soft tissues changes following implant explantation. To evaluate the radiographic bone healing and the horizontal and vertical soft tissue dimensional alterations at implant extraction alveoli, 6 months following implant explantation. Data from 31 patients scheduled for extraction of one implant with persisting peri-implantitis despite treatment were analysed. Bone crest level changes and the extent of bone healing at the apical aspect of the implant socket were assessed on the radiographs prior and 6 months following explantation. Regression analyses assessed the impact of various predictors (e.g., bone crest level, presence/absence of buccal bone) on bone level changes. Fisher's exact probability test was applied to assess the difference in probability to have mucosa recession of ≥2 mm in the presence or absence of alveolar buccal bone. A vertical bone loss of 0.8 mm (standard deviation [SD] = 1.3) of the peri-implant bone crest and a gain of 0.8 mm (SD = 1.1) from the bottom of the peri-implant defect were recorded. Complete healing was noted in the intact implant extraction socket (i.e., the part of the implant not affected by peri-implantitis). A reduction of 0.4 mm (SD = 0.7) of the alveolar mucosa height was recorded in concomitant with a decrease of 0.7 mm (SD = 0.8) of the mucosa width. These alterations were more pronounced in the absence of the alveolar buccal bone. The results of the present explorative study indicated a decrease in the height and width of the alveolar soft and hard tissues following explantation of peri-implantitis affected implants, and these changes were more pronounced in the absence of the buccal bone wall. Nevertheless, the apical portion of the implant alveolus (the intact implant socket) tend to heal with no further bone loss.

Marginal Bone Stability of Implants Placed in Alveolar Ridge Preservation Areas: a Preliminary Retrospective Analysis

<p>Abstract: After tooth extraction, the alveolar ridge undergoes resorption and atrophy, which usually leads to a wide range of tissue dimensional changes. Preservation of the alveolar ridge can maintain its volume, reduce ridge resorption, and help subsequent dental implant treatment. This retrospective cohort study aims to investigate the marginal bone stability of implants placed in alveolar ridge preservation areas using deproteinized bovine bone mineral with 10% collagen (DBBM-collagen) combined with a native collagen membrane (CM). In this study, forty-seven implant sites divided into either intact or defective extraction sockets were included, using vertical bite-wing films to measure the bone level at baseline, 6 months, and 12 months after implant prosthesis placement. The result of peri-implant mean bone loss was -0.03 ± 0.84mm at 12 months compared to baseline. There was no significant difference in mesial and distal sites compared to baseline. In addition, no significant difference was found between the defective and intact sockets for marginal bone changes. Therefore, ridge preservation combined with DBBM-collagen and CM can provide an ideal alveolar ridge, simplify dental implant procedures, and maintain implant marginal bone stability.</p> <p> </p>

Kinetics of Phenotype Modification Therapy with VISTA: A Retrospective Case Series Using 3D Digital Analysis

Phenotype modification therapy has emerged as one of the main treatment objectives of periodontal plastic surgery. However, long-term data on the stability of gingival thickness gains are not available. This study examined the kinetics of mucosal thickness gain as a measure of phenotype modification therapy following treatment of multiple gingival recession defects with vestibular incision subperiosteal tunnel access (VISTA). Six patients with 14 recession type (RT) II teeth were treated using VISTA and subepithelial connective tissue grafts (SCTG). Scanned images of study casts at pre- and postoperative periods (6 to 66 months) were digitally superimposed for quantitative evaluation of soft tissue dimensional changes. Mucosal thickness gains ranged from 1.0 ± 0.7 mm (1 mm apical to cement-enamel junction [CEJ]) to 1.4 ± 0.4 mm (5 mm apical to CEJ). The gingival thickness gains remained relatively stable, with thickness gains at 66 months of 0.5 ± 0.8, 0.9 ± 0.6, 1.1 ± 0.6, 1.0 ± 0.4, and 1.2 ± 0.6 mm at 1, 2, 3, 4 and 5 mm apical to the CEJ, respectively. Treatment of multiple gingival recession defects with VISTA and SCTG led to stable gingival thickness gains and shows promise as a strategy for phenotype modification therapy.

Optimizing dimensional changes of soft tissue in alveolar ridge preservation using rotational palatal pedicle flap in posterior maxilla – A randomized controlled clinical trial

After tooth extraction, it is critical to maintain alveolar bone proportions as well as soft tissue integrity for rehabilitation. The common procedure for closing the socket is a coronally advanced flap, however, it compromises the keratinized tissue dimensions. As a result, the current study's goal is to assess and compare the soft tissue dimensional alterations caused by the new palatal rotational pedicle flap versus the conventional coronally advanced flap as an adjunct to alveolar ridge preservation. Fifty-four participants requiring extraction of single maxillary posterior teeth were randomized into two groups. While both groups used a 1:1 mixture of demineralized freeze dried bone allograft and platelet rich fibrin to preserve the ridge after atraumatic extraction, the control group used a coronally advanced flap to seal the socket, whereas the test group used a rotational palatal pedicle flap to close the socket. At baseline, 3 and 6 months after surgery, the clinical parameters, i.e., vertical ridge height (VRH), horizontal ridge width (HRW), width of keratinized gingiva (WKG), thickness of keratinized gingiva (TKG), and papillary height (PH) were measured. Intergroup comparison demonstrated a significantly greater gain in WKG (P = 0.001), TKG (P = 0.029) and PH (P = 0.021) in the test group. The VRH and HRW, on the other hand, were preserved in both groups. The data were analyzed using unpaired t-test for intergroup and analysis of variance for intragroup comparison. Both groups effectively preserved hard tissue dimensional changes, with the test group showing superior soft tissue enhancement.

Evaluation of Dimensional Changes and Ridge Contour Around Ovate Pontics Inserted Immediately After Extraction with Alveolar Ridge Preservation in the Esthetic Zone.

Alveolar ridge preservation (ARP) is indicated to attenuate anatomic and physiologic changes following tooth extraction. A properly contoured ovate pontic placed immediately into an extraction socket may be adequate to maintain alveolar ridge architecture for improved esthetic results. This prospective clinical study evaluated the ability of immediately placed ovate pontics in conjunction with ARP to attenuate postextraction tissue dimensional changes in the esthetic zone and maintain alveolar ridge contour. Ten patients (11 sites) completed the study. All subjects received a combination of socket grafting with allogeneic particulate graft material and socket sealing with an ovate pontic provisional restoration. A set of clinical linear and volumetric outcomes were assessed after a 6-month healing period. At 6 months postoperative, the linear measurements for the mean ridge dimensional loss were 0.9 ± 0.6 mm (range: 0.2 to 1.8 mm) in height and 1.4 ± 0.6 mm (range: 0.1 to 2.4 mm) in width. The mean volumetric tissue loss observed was 24.4 ± 15.4 mm3 (range: 2.6 to 50.1 mm3) at 3 months postoperative and 32.2 ± 14.2 mm3 (range: 3.8 to 50.5 mm3) at 6 months postoperative. Resorption pattern assessment showed the overall cervical area to have less resorption than the apical areas at 6 months postoperative, with the least amount of resorption in the midbuccal cervical section. When compared to the data of a previous pilot study, no statistically significant difference was seen between the dimensional losses when using ovate pontics with and without ARP. This may be evidence that the use of an ovate pontic provisional restoration immediately after extraction effectively attenuates postextraction dimensional changes.

The Conometric Concept: Definitive Rehabilitation of a Single Posterior Implant Using a Friction Retention Abutment. A 1-year Follow-up Report

To provide a 1-year assessment of friction-retention abutments (Acuris, Dentsply Sirona) used to retain a single lithium disilicate (LS2) monolithic restoration. A total of 522 implants were placed to treat single-tooth premolar and molar edentulous sites in the mandible or maxilla. Three types of implants were used. The tested abutments were connected 3 months after implant placement. A single pressed LS2 monolithic restoration was cemented to a dedicated titanium cap and engaged to the abutment without the use of screws or cement. Any complications affecting the restoration or the opposing dentition, soft tissue dimensional changes, the distance between the implant platform and the bone peak, and pocket probing depths were recorded at the time of restoration placement (T0), after 6 months of function (T1), and after 1 year of function (T2). Esthetic, functional, and biologic parameters were recorded at T0 and T2. A total of 507 patients (284 women and 223 men) received a restoration (T0), and 504 of them reached the T2 1-year follow-up. One restoration fractured after 10 months in function. No statistically significant difference was assessed in the soft tissue measurements or in the measurements of the distance between the supporting implant platform and the bone peak. None of the restorations detached during the observation period. The friction retention abutment is a viable option to retain an implant-supported monolithic LS2 glass-ceramic restoration in cases of premolar or molar single-tooth edentulism.

The Effect of Melatonin and Hyaluronic Acid Mixture on Hard Tissue Dimensional Changes Around Immediate Post-Extraction Implants.

The Effect of Melatonin and Hyaluronic Acid Mixture on Hard Tissue Dimensional Changes Around Immediate Post-Extraction Implants.

Comparative Efficacy of Different Flapless Ridge Preservation Techniques: A Systematic Review and Meta-Analysis.

Although the efficacy of ridge preservation is well documented, there is a lack of robust evidence regarding the influence of different surgical techniques. Flapless approaches are thought to be better at preserving soft tissue architecture and have been suggested for mild to moderate defects. This review investigates the efficacy of different flapless techniques for ridge preservation in mild to moderate defects with <50% buccal bone loss. PubMed, EMBASE, and Cochrane Library databases were searched to obtain relevant articles published in English from 1974 to December 2019. The primary outcome was horizontal and vertical hard tissue dimensional changes. Soft tissue changes were evaluated as a secondary outcome. The Bio-Col technique, subperiosteal tunnel technique, and hard tissue with autogenous soft tissue graft/collagen matrix technique were identified. Eight studies were included, and quantitative analyses were performed for 4 studies for the primary outcome variables. The meta-analysis revealed significant reductions for horizontal changes (weighted mean difference [WMD] = 2.56 mm, 95% CI [2.18, 2.95]), vertical mid-buccal (WMD = 1.47 mm, 95% CI [1.04, 1.90]), and vertical mid-lingual (WMD = 1.28 mm, 95% CI [0.68, 1.87]) in favor of flapless ridge preservation techniques. Subgroup analysis based on technique suggests minimal hard tissue differences. The efficacy of flapless ridge preservation techniques on soft tissue changes was inconclusive. In conclusion, flapless ridge preservation techniques are effective for mild to moderate defects. The technique or material used to close the extraction socket does not seem to significantly affect hard tissue changes, while the effect on soft tissue changes warrants further investigation.

Immediate implant placement combining socket seal abutment and peri-implant socket filling: A prospective case series.

The aim of this prospective case series was to assess the implant outcomes as well as hard and soft tissue dimensional changes of immediate implant placement in posterior sites using a custom-made sealing socket abutment (SSA) combined to peri-implant socket filling (PISF). Twenty patients were considered for single extraction and immediate implant in upper or lower posterior regions. The remaining peri-implant sockets were filled with Deproteinized Bovine Bone Mineral. Based on intra-oral scans (IOS), custom-made SSAs were placed the same day. Implant survival rate, peri-implant bone changes, peri-implant health and pink esthetic score (PES) were recorded up to 1year post-implant placement. Moreover, CBCT and IOS were performed to monitor hard and soft tissue dimensional changes. One implant failed to osseointegrate leading to an implant survival rate of 95% after 1year. Peri-implant bone changes yielded 0.19±0.31mm and 84.2% of the implants displayed no or mild bleeding on probing. Horizontal bone remodeling was not significant from baseline to 1year at any levels. Finally, soft tissue profile was stable in the most cervical area while minor changes occurred during the first 6months below the gingival margin. The absence of mid-buccal recession (0.07mm) and good PES were found after 1year. Despite its limitations, this study showed that immediate implants in the posterior region using the SSA+PISF protocol resulted in promising implant outcomes with limited hard and soft tissue dimensional changes while decreasing the overall treatment time.

Comparison of the soft and hard peri-implant tissue dimensional changes around single immediate implants in the esthetic zone with socket shield technique versus using xenograft: A randomized controlled clinical trial.

Compare the dimensional changes of the peri-implant soft and hard tissues clinically and radiographically around single immediate implants in the esthetic zone with socket shield technique versus filling the buccal gap with xenograft. Forty-two patients with a single non-restorable tooth in the esthetic zone replaced with an immediate implant were randomly assigned either to the socket shield technique (test) or to grafting the buccal gap with xenograft (control). The vertical and horizontal buccal bone resorption were measured 6-months following implant placement. The esthetic outcomes were evaluated by assessing the Pink Esthetic Score (PES) and the amount of midfacial mucosal alteration, in addition to patient satisfaction assessment through a Visual Analogue Scale (VAS) based questionnaire 1-year following implant restoration. The present study showed that the socket shield group yielded significantly less vertical and horizontal buccal bone resorption of 0.35 (±0.62) mm and 0.29 (±0.34) mm compared to 1.71 (±1.02) mm and 1.45 (±0.72) mm in the xenograft group respectively. Also, there was a significantly greater midfacial mucosal recession in the xenograft group of 0.466 (±0.58) mm compared to midfacial mucosal coronal migration of 0.45 (±0.75) mm in the socket shield group. However, there was no statistically significant difference regarding the total PES and patient satisfaction in both treatment groups. The socket shield technique can preserve hard and soft peri-implant tissues following immediate implant placement. (ClinicalTrials.gov Identifier: NCT03684356).

Hard tissue dimensional changes following implant removal due to peri-implantitis: A retrospective study.

The current evidence regarding the alterations experienced by the alveolar ridge (hard tissue changes) after implant removal due to peri-implantitis is limited. To assess the hard tissue dimensional changes following implant removal due to peri-implantitis. Clinical records were examined to identify patients with implants that had to be removed due to a hopeless prognosis secondary to peri-implantitis due to expendability of peri-implantitis implants for functional reasons. Patients with preoperative and postoperative cone-beam computed tomography (CBCT) scans were included. Patient-related, implant-related, and surgery-related factors were assessed based on the clinical records. Linear measurements were made to evaluate the influence of bone plate thickness (BPT), ridge width (RW), and ridge height (RH) at various levels upon the outcome of implant removal. A descriptive statistical analysis of the quantitative and qualitative variables was performed. Correlations of the variables with the primary outcome (dimensional changes) were tested using univariate and multivariate analyses (multinomial random intercept mixed model linear regressions). A total of 26 patients (nimplants = 79) met the eligibility criteria. The mean decrease in RW at 1 and 3 mm below the crest was 11.3% and 4.4%, respectively (P < 0.001). Buccal and lingual RH was significantly reduced by 2.2% and 6.3%, respectively (P < 0.001). Few patient-related, implant-related, and surgery-related factors appeared to have an impact upon the hard tissue dimensional changes. Bone regeneration simultaneous to implant removal minimized the dimensional changes of the ridge both vertically (5% lesser buccal RH reduction) and horizontally (12% lesser RW reduction) when compared with spontaneous healing. The use of a reverse-torque removal kit seemed to be critical in limiting the dimensional changes of the ridge. Minimal hard tissue changes can be expected following implant removal due to peri-implantitis. Simultaneous bone regeneration procedures and the use of a removal kit may considerably reduce the impact upon the dimensional changes (NCT04534361).

The effect of immediate implant placement on alveolar ridge preservation compared to spontaneous healing after tooth extraction: Soft tissue findings from a randomized controlled clinical trial.

To compare soft tissue dimensional changes and relative differences in soft and hard tissue volumes 4months after single-tooth extraction and three different treatment modalities: spontaneous healing (SH) and alveolar ridge preservation by means of a deproteinized bovine bone mineral and a collagen matrix, with (IMPL/DBBM/CM) or without (DBBM/CM) immediate implant placement. STL files from study casts obtained at baseline and after 4months were matched to calculate buccal soft tissue linear and volumetric changes. DICOM files from CBCTs were superimposed to STL files allowing the evaluation of soft tissue thickness at baseline and 4months. Mean horizontal reduction accounted for 1.46±0.20 (SH), 0.85±0.38 (DBBM-CM) and 0.84±0.30 IMPL/DBBM-CM, with no statistical differences. Soft tissue thickness had a significant mean increase of 0.95 for SH group, compared to a non-significant mean decrease for DBBM-CM (0.20) and IMPL/DBBM-CM groups (0.07). A preservation technique with DBBM-CM, with or without immediate implant placement, did not reduce the horizontal linear and volumetric changes at the buccal soft tissue profile significantly at 4months after tooth extraction when compared to spontaneous healing. This is due to a significant increase in soft tissue thickness in spontaneously healing sites.

Impact of treatment modality after tooth extraction on soft tissue dimensional changes: RCT

Impact of treatment modality after tooth extraction on soft tissue dimensional changes: RCT

Denture-reversing technique for assessing the soft tissue dimensional changes according to artificial tooth position in completely edentulous patients

A digital workflow to assess the soft tissue dimensional changes in completely edentulous patients is described. Diagnostic casts obtained at 2 time points and the complete denture were scanned by using a desktop scanner. The denture scan was inverted by using a metrology software program to obtain the soft tissue contour. Using this reversed file as a reference, the file and 2 scan files obtained at different time points were aligned individually with the best fit alignment function. The scanned denture file and the 2 realigned scan files were imported into the same software. A plane vertical to the occlusal plane was determined such that it moved anteroposteriorly. The distance between the contours of the 2 realigned files was measured by selecting a point and a vector based on the artificial tooth positions of the denture. This technique of using a reversed denture file may provide a quantitative evaluation of soft tissue changes and further aid in determining appropriate intervals for denture relining or rebasing.

Systematic Review and Meta-Analysis of Hard Tissue Outcomes of Alveolar Ridge Preservation.

Alveolar ridge preservation procedures have been advocated to minimize postextraction dimensional loss. There is a need for systematic analyses of clinical factors affecting the outcomes of these procedures in order to improve their clinical outcomes. This systematic review and meta-analysis aimed to assess the efficacy of alveolar ridge preservation procedures in terms of hard tissue dimensional changes and to determine clinical factors affecting outcomes of these procedures. Studies comparing alveolar ridge preservation procedures with tooth extraction alone that reported quantitative outcomes for hard tissue dimensional changes were included. The primary outcome variable was horizontal dimensional changes of alveolar bone. Subgroup analyses evaluated effects of wound closure, flap elevation, type of grafting materials, use of barrier membranes, use of growth factors, socket morphology, and the position of teeth on outcomes of alveolar ridge preservation procedures. Twenty-one studies were included, and quantitative analyses were performed for seven outcome variables. Significant differences between alveolar ridge preservation and control sites were found for six outcome variables, all favoring alveolar ridge preservation procedures. The magnitude of effect for the primary outcome variable (horizontal dimensional changes of alveolar bone) was 1.86 mm (95% CI = 1.44, 2.28; P < .001). This magnitude of effect for the primary variable (as determined by subgroup analysis) was also significantly affected by type of wound closure (P = .033), type of grafting materials (P = .001), use of barrier membranes (P = .006), use of growth factors (P = .003), and socket morphology (P < .001). Alveolar ridge preservation procedures are effective in minimizing postextraction hard tissue dimensional loss. The outcomes of these procedures are affected by morphology of extraction sockets, type of wound closure, type of grafting materials, use of barrier membranes, and use of growth factors.

Tissue Dimensional Changes in Single-Tooth Immediate Extraction Implant Placement in the Esthetic Zone: A Retrospective Clinical Study.

The aim of this study was to evaluate the buccopalatal volumetric tissue change that occurs following flapless single-tooth immediate extraction placement in the esthetic area and to analyze the role of four different variables. Patients in need of a single-tooth replacement in the anterior maxillary or mandibular area (premolar to premolar) were recruited for the study. Patients were treated using four different therapeutic modalities: group 1 (healing abutment), group 2 (healing abutment + bone graft), group 3 (provisional restoration), and group 4 (provisional + bone graft). Alginate impressions were taken the day of implant insertion before tooth extraction (T0), at 1 month (T1), at 3 months (T2), and at 6 months (T3). Buccopalatal dimension (BPD) was measured on the study casts at 1, 3, and 5 mm apical to the free gingival margin and compared between T0 and T1 and T2 and T3. Seventy-seven patients were included in the study, 29 men and 48 women with a mean age of 54 years (range: 24 to 76 years), and 80 implants were inserted. Thirteen implants were inserted in group 1, 13 in group 2, 20 in group 3, and 34 in group 4. The BPD contraction was more evident for group 1, smaller in group 2 and group 3, and minimal in group 4. Repeated measures analysis of variance (ANOVA) and post hoc tests were used. The data analyzed were considered statistically significant with a level of α = .05. The interaction effect P value was numerically zero. The results of this study seem to indicate that volumetric tissue changes after immediate extraction placement in the esthetic area can be minimized if a provisional is immediately connected and a bone graft is inserted simultaneously.

Quantification of tissue dimensional changes during preparation of histopathological specimen

Quantification of tissue dimensional changes during preparation of histopathological specimen

Tissue Dimensional Changes Following Alveolar Ridge Preservation with Different Xenografts Associated with a Collagen Membrane. Results at the 4-Month Re-Entry Surgery

Tissue Dimensional Changes Following Alveolar Ridge Preservation with Different Xenografts Associated with a Collagen Membrane. Results at the 4-Month Re-Entry Surgery

Three-Dimensional Volumetric Changes in Severely Resorbed Alveolar Sockets After Ridge Augmentation with Bovine-Derived Xenograft and Resorbable Barrier: A Preliminary Study on CBCT Imaging.

The primary aim of the study was to describe a novel technique to evaluate volumetric hard tissue dimensional changes after ridge augmentation procedures. The secondary aim was to apply this newly developed measuring method to compromised alveolar sockets grafted with a slowly resorbing biomaterial covered with a collagen membrane. Eleven patients (6 men and 5 women, mean age 52.7 ± 8.3 years) requiring extraction of one hopeless tooth for severe periodontitis in the maxillary anterior area were consecutively treated with a ridge augmentation procedure. All experimental sockets showed advanced buccal bone plate deficiency and were grafted with deproteinized bovine bone mineral with 10% collagen covered with a collagen membrane. Sockets healed by secondary intention. Three-dimensional volumetric alveolar bone changes were calculated by superimposing cone beam computed tomography scans obtained before and 12 months after the augmentation procedure. After 12 months, the alveolar mineralized tissue filled 91.20% ± 7.96% of the maximum volume for regeneration. The augmentation procedure appeared not only to compensate for bone remodeling in most alveolar regions but also to repair a significant portion of the buccal wall. The most significant ridge width changes occurred 1 mm apical to the bone crest (2.33 ± 1.46 mm, P < .001). Within present limitations, this radiographic measuring methodology can be a useful tool to evaluate changes in socket volume. A ridge preservation technique performed with collagenated bovine bone and a collagen membrane was able to improve ridge shape and dimensions in compromised alveolar sockets.

Immediate implant placement and restoration in the anterior maxilla: Tissue dimensional changes after 2-5 year follow up.

Immediate implant placement followed by an immediate restoration has proven to be a viable technique in the anterior maxillary region. This prospective study evaluated the mid-long term (2-5 years) tissue changes around immediately placed and restored implants in the anterior maxilla using flapless surgery and simultaneous hard tissue augmentation. Thirty AstraTech implants were immediately placed in 30 patients, followed by the delivery of an immediate provisional restoration on the same day. All participating 30 patients underwent the same treatment strategy that involved flapless removal of a failing maxillary anterior tooth, immediate implant placement, simultaneous augmentation with a deproteinized particulate xenograft, followed by the connection of a screw-retained provisional restoration. Radiographs and photographs were used to measure hard and soft tissue changes. Aesthetic evaluation was performed using the Pink Esthetic Score (PES). All implants remained osseointegrated during the follow up period of 2-5 years (mean 47 ± 15 months). Twelve of the thirty patients completed the 5 year follow up. Radiographic evaluation revealed average gains in bone levels of 0.18 and 0.34 mm mesially and distally, respectively. Soft tissue evaluation showed a mean tissue loss of 0.05 ± 0.64 mm and 0.16 ± 0.63 mm at the mesial and distal papillae, respectively, while mid-facial mucosal recession was 0.29 ± 0.74 mm. A significant improvement in the Pink Esthetic Scores was seen at the final follow-up (mean PES 11.50), as compared to the baseline (mean PES 10.27) (P = .001). In addition to a favorable implant success rate and peri-implant bony response, the soft tissue levels and overall aesthetics around single immediately placed and restored implants can also be maintained in the mid-long term.