Time-averaged Intensity Research Articles

Experimental Investigation on Velocity Field in Subterranean Water Flow Under Different Size of Gravel

Direct measurement of flow velocities within subterranean layer is important for predicting subterranean flow. The authors conducted a study on the velocity field of subterranean water flow by directly measuring the flow velocity within the subterranean layer using crushed stone to form a gravel mount. Namely, they directly measured subterranean flow velocities for five different sizes of gravels (5.3 mm, 16.5 mm, 25.5 mm, 47.5 mm, and 92.4 mm) and showed for the first time how the time-averaged flow velocity and standard deviation vary with the size of the gravels. The velocity field including turbulent intensity in the subterranean layer was revealed, and the flow field of the subterranean flow depends on the size of the gravels that make up the gravel mount. The relationship between the configuration of the gravel mount, the water surface profile, and the velocity field within the subterranean layer allowed a discussion of the vertical distribution of time-averaged velocities and standard deviations, as well as stream wise changes in the subterranean layer. From the results of time-averaged velocity and turbulent intensity (here, standard deviation) in the subterranean layer for different sizes of gravels, it is possible to estimate the velocity field of subterranean water flow formed by the grain size distribution of the depositing gravels and the difference in water level. In other words, by clarifying the velocity field of subterranean water flow consisting of different gravel sizes, it may be possible to evaluate the subterranean function of the sand and gravel zone deposited by transported gravels.

Microscopic deconstruction of cortical circuit stimulation by transcranial ultrasound.

Transcranial Ultrasound Stimulation (TUS) can noninvasively and reversibly perturb neuronal activity, but the mechanisms by which ultrasound engages brain circuits to induce functional effects remain unclear. To elucidate these interactions, we applied TUS to the cortex of awake mice and concurrently monitored local neural activity at the acoustic focus with two-photon calcium imaging. We show that TUS evokes highly focal responses in three canonical neuronal populations, with cell-type-specific dose dependencies. Through independent parametric variations, we demonstrate that evoked responses collectively scale with the time-average intensity of the stimulus. Finally, using computational unmixing we propose a physiologically realistic cortical circuit model that predicts TUS-evoked responses as a result of both direct effects and local network interactions. Our results provide a first direct evidence of TUS's focal effects on cortical activity and shed light on the complex circuit mechanisms underlying these effects, paving the way for TUS's deployment in clinical settings.

Orifice Versus Converging-Nozzle Grid Turbulence: A Wavelet Perspective

Grids such as perforated plates are of fundamental importance in flow turbulence study and are commonly utilised to promote mixing. An orificed perforated plate (OPP) and its reversed counterpart, the converging-nozzle perforated plate (CNPP), were applied to produce quasi-isotropic turbulence inside a wind tunnel. The three orthogonal velocity components were measured using a triple hotwire at 10D downstream of the perforated plate for Reynolds numbers, ReD, 18,700 and 28,400, where D is the diameter of the perforated holes. The statistics of the grid-generated turbulence was analysed using the time-averaged local velocity profile and turbulence intensity, which revealed a more homogeneous distribution of the flow field with a higher level of turbulence for the OPP. Fourier and wavelet analyses were employed to investigate the energy of the eddies as a function of frequency and multiscale characteristics of the fluctuating velocity, respectively. At ReD = 18,700, the turbulent energy remains prominently with large-scale vortical structures which are non-intermittently present in the flow for both perforated plates. The thickness of the converging channels of the CNPP appears to provide the venue for spawning intermittent fluctuations. At higher ReD 28,400, the effect of this intermittent behaviour becomes evident for the CNPP, leading to a multiscale distribution of turbulent energy.

Simulation of the reflection of a high energy laser beam at the sea surface for hazard and risk analyses

The application of a high energy laser beam in a maritime scenario necessitates a laser safety concept to prevent injury to personnel or uninvolved third parties from uncontrolled reflections of laser light from the sea surface. Therefore, it is crucial to have knowledge of the amount and direction of reflected laser energy, which varies statistically and depends largely on the dynamics of the wavy sea surface. These dynamics are primarily influenced by wind speed, wind direction, and fetch. An analytical model is presented for calculating the time-averaged spatial intensity distribution of the laser beam reflected at the dynamic sea surface. The model also identifies the hazard areas inside which laser intensities exceed a fixed exposure limit. Furthermore, as far as we know, our model is unique in its ability to calculate the probabilities of potentially eye-damaging glints for arbitrary observer positions, taking into account the slope statistics of gravity waves. This is a critical first step toward an extensive risk analysis. The simulation results are presented on a hemisphere of observer positions with fixed radii from the laser spot center. The advantage of the analytical model over our numeric (dynamic) model is its fast computation time. A comparison of the results of our new analytical model with those of the previous numerical model is presented.

Performance study of a central reentrant step pilot-flameholder in a dual-mode combustor

The augmented/ramjet combustion chambers are characterized by wide operating ranges, large flow state variations, and harsh operating conditions. The reliable ignition of these chambers urgently needs to be achieved. To improve the pilot ignition and blowout performance based on the centerbody in augmented/ramjet combustion chambers, a reentrant step flameholder is proposed on the basis of a conventional backward step. In this paper, the flow characteristics, ignition and blowout boundary under the non-premixed inflow, dynamic ignition process and flame stabilization mechanism of the reentrant step flame holder are investigated by using an experimental method with numerical simulation. The results show that the reentrant step flame holder exhibits better ignition and blowout performance than the conventional step flame holder without increasing the flow resistance. The ignition and blowout equivalence ratios of the reentrant step flame holder decrease by 22.86 % and 24.34 %, respectively, compared with those of the conventional step flame holder. The radial reentrant expansion is more effective than the axial reentrant expansion. Analyzing different reentrant structures shows that radial expansion can shorten the ignition delay time and improve the time-averaged integral flame intensity; axial expansion can improve the time-averaged integral flame intensity and reduce the flame pulsation rate; and the structure Da30Dr30 (the conventional step structure expands axially and radially by 30 mm simultaneously within the centerbody.) whose pilot flames are all stabilized in front of the reentrant step flame holder under different incoming flow conditions, exhibits the best ignition and blowout performances.

Flow Characteristics in Partly Vegetated Channels: An Experimental Investigation

In this study, we attempt to experimentally investigate the flow turbulence structure in a partly vegetated channel. To achieve the objective of this study, we conducted extensive measurements of flow velocities within and outside the vegetated area, where the flow is fully developed. The experiments were conducted in a very large channel at the Coastal Engineering Laboratory of the Department of Civil, Environmental, Building Engineering and Chemistry at the Polytechnic University of Bari, Italy. The instantaneous three flow velocity components were accurately measured using a 3D-Acoustic Doppler Velocimeter (ADV)-Vectrino system at high frequency. Flow behaviors through the vegetated area, at the interface, and in the unobstructed area were analyzed via time-averaged velocities, turbulence intensity, correlation properties, spectral analysis, and vortex identification. Experimental results showed the development of three distinct characteristic flow zones: (i) a vegetated area of low streamwise velocity, high turbulence intensities, dominant inward interactions, and more intense power spectrum, (ii) a shear layer zone of increasing streamwise velocity, more enhanced transverse flow motion, exponential decrease in turbulence intensities, and frequent ejection and/or outward interaction events, and (iii) a free-stream zone of higher and almost constant streamwise velocity, lower turbulence intensities, frequent sweep and/or inward interaction events, and less intense streamwise power spectrum. The results brought further insights into the flow behaviors in these characteristic flow zones. The extensive and detailed measured data can provide a basis for improving and calibrating numerical simulations of partly vegetated channels.

Low-intensity pulsed ultrasound activated the anti-tumor immunity by irradiating the spleen of mice in 4 T-1 breast cancer

Tumor immunotherapy is booming around the world. However, strategies to activate the immune system and alleviate the immunosuppression still need to be refined. Here, we demonstrate for the first time that low-intensity pulsed ultrasound (LIPUS, spatial average time average intensity (Isata) is 200 mW/cm2, frequency is 0.3 MHz, repetition frequency is 1 kHz, and duty cycle is 20%) triggers the immune system and further reverses the immunosuppressive state in the mouse models of breast cancer by irradiating the spleen of mice. LIPUS inhibited tumor growth and extended survival in mice with 4 T-1 tumors. Further studies had previously shown that LIPUS enhanced the activation of CD4+ and CD8+ T cells in the spleen and led to significant changes in cytokines, as well as induced upregulation of mRNA levels involved in multiple immune regulatory pathways in the spleen. In addition, LIPUS promoted tumor-infiltrating lymphocyte accumulation and CD8+ T cell activation and improved the dynamics of cytokines/chemokines in the tumor microenvironment, resulting in a reversal of the immunosuppressive state of the tumor microenvironment. These results suggest a novel approach to activate the immune response by irradiating the spleen with LIPUS.

Flame stabilization characteristics in the supersonic combustor based on a circular cross-section strut

Flame stabilization characteristics in the supersonic combustor with a circular cross-section strut were experimentally investigated. The Mach number, stagnation pressure, and stagnation temperature of the inflow were 2.52, 1.60 MPa, and 1486 K, respectively. Compared to the wedge-shaped recirculation flow at the base of the rectangular cross-section strut, the conical recirculation flow at the base of the circular cross-section strut possessed a more favorable geometry characterized by a longer length, a larger volume, and a small surface. When fueled by hydrogen, the combustor equipped both with a circular cross-section strut and a rectangular cross-section strut could achieve self-sustaining combustion. In the tests with equivalence ratios of 0.08 and 0.12, the time-averaged flame chemiluminescence intensity in the combustor with a circular cross-section strut was higher than its counterpart in the combustor with a rectangular cross-section strut by 80% and 53%, respectively. Nevertheless, the standard deviations of the flame chemiluminescence intensities showed an opposite trend. Therefore, the reaction zone downstream of the circular cross-section strut was more vigorous and stable. When both kerosene and hydrogen were supplied to the combustor, these two struts failed to stabilize the flame. Although an unsteady hydrogen–kerosene flame was witnessed in the combustor, it extinguished within 2 ms because the recirculation flow at the base of the strut was too small. Shock wave generators were employed to enhance the flame stabilization ability of the strut with a circular cross section. The experimental results suggested that shock wave generators significantly enlarged the recirculation flow and created a region with high temperature and high pressure. The self-sustaining hydrogen–kerosene flame was achieved in the combustor equipped with shock wave generators.

Fluorescence Bar-Coding and Flowmetry Based on Dark State Transitions in Fluorescence Emitters.

Reversible dark state transitions in fluorophores represent a limiting factor in fluorescence-based ultrasensitive spectroscopy, are a necessary basis for fluorescence-based super-resolution imaging, but may also offer additional, largely orthogonal fluorescence-based readout parameters. In this work, we analyzed the blinking kinetics of Cyanine5 (Cy5) as a bar-coding feature distinguishing Cy5 from rhodamine fluorophores having largely overlapping emission spectra. First, fluorescence correlation spectroscopy (FCS) solution measurements on mixtures of free fluorophores and fluorophore-labeled small unilamellar vesicles (SUVs) showed that Cy5 could be readily distinguished from the rhodamines by its reversible, largely excitation-driven trans-cis isomerization. This was next confirmed by transient state (TRAST) spectroscopy measurements, determining the fluorophore dark state kinetics in a more robust manner, from how the time-averaged fluorescence intensity varies upon modulation of the applied excitation light. TRAST was then combined with wide-field imaging of live cells, whereby Cy5 and rhodamine fluorophores could be distinguished on a whole cell level as well as in spatially resolved, multiplexed images of the cells. Finally, we established a microfluidic TRAST concept and showed how different mixtures of free Cy5 and rhodamine fluorophores and corresponding fluorophore-labeled SUVs could be distinguished on-the-fly when passing through a microfluidic channel. In contrast to FCS, TRAST does not rely on single-molecule detection conditions or a high time resolution and is thus broadly applicable to different biological samples. Therefore, we expect that the bar-coding concept presented in this work can offer an additional useful strategy for fluorescence-based multiplexing that can be implemented on a broad range of both stationary and moving samples.

Wind Noise Estimation Method in Low-Frequency Sound Measurement in Windy Outdoor Environment

It is generally known that low-frequency sound is affected by natural winds when measured on-site. In this paper, the estimation method of wind noise by wind tunnel and outdoor natural wind has been examined step by step. Firstly, wind tunnel experiments were conducted to confirm the relationship between wind velocity time average values and turbulence intensity, and to create the estimation fornula. Secondary, the field experiment was conducted using a low-frequency sound generator as a sound source, and the different results between the wind tunnel experiment and outdoor experiment were discovered. Then, we accumulated the field data in different roughness divisions and tried to create the wind noise estimation fornula at each point. As a result, we considered the different results according to the roughness division and obtained the results that it is possible to estimate the wind noise by using the proposed estimation fornula.

Space-time wave packets with reduced divergence and tunable group velocity generated in free space after multi-mode fiber propagation.

Previously, space-time wave packets (STWPs) have been generated in free space with reduced diffraction and a tunable group velocity by combining multiple frequency comb lines each carrying a single Bessel mode with a unique wave number. It might be potentially desirable to propagate the STWP through fiber for reconfigurable positioning. However, fiber mode coupling might degrade the output STWP and distort its propagation characteristics. In this Letter, we experimentally demonstrate STWP generation and propagation over 1-m graded-index multi-mode fiber. Fiber mode coupling is mitigated by pre-distortion according to the inverse matrix of the fiber mode coupling matrix. Measurement of the STWP at the fiber output shows that its group velocity can vary from 1.0042c to 0.9967c by tuning the wave number of the Bessel mode on each frequency. The measured time-averaged intensity profiles show that the beam radius remains similar after 150-mm free-space propagation after exiting the fiber.

Universal linear intensity transformations using spatially incoherent diffractive processors

Under spatially coherent light, a diffractive optical network composed of structured surfaces can be designed to perform any arbitrary complex-valued linear transformation between its input and output fields-of-view (FOVs) if the total number (N) of optimizable phase-only diffractive features is ≥~2NiNo, where Ni and No refer to the number of useful pixels at the input and the output FOVs, respectively. Here we report the design of a spatially incoherent diffractive optical processor that can approximate any arbitrary linear transformation in time-averaged intensity between its input and output FOVs. Under spatially incoherent monochromatic light, the spatially varying intensity point spread function (H) of a diffractive network, corresponding to a given, arbitrarily-selected linear intensity transformation, can be written as H(m, n; m′, n′) = |h(m, n; m′, n′)|2, where h is the spatially coherent point spread function of the same diffractive network, and (m, n) and (m′, n′) define the coordinates of the output and input FOVs, respectively. Using numerical simulations and deep learning, supervised through examples of input-output profiles, we demonstrate that a spatially incoherent diffractive network can be trained to all-optically perform any arbitrary linear intensity transformation between its input and output if N ≥ ~2NiNo. We also report the design of spatially incoherent diffractive networks for linear processing of intensity information at multiple illumination wavelengths, operating simultaneously. Finally, we numerically demonstrate a diffractive network design that performs all-optical classification of handwritten digits under spatially incoherent illumination, achieving a test accuracy of >95%. Spatially incoherent diffractive networks will be broadly useful for designing all-optical visual processors that can work under natural light.

Instantaneous and time-averaged intensity flow measurements in scale models.

Current methods of representing energy flows in rooms have been limited to stationary pressure contour maps or intensity vectors derived from finite-element modeling (FEM) software. Despite recent advances in FEM analysis, such models are at best approximations of real-world phenomena because of the assumptions made in obtaining these results. This paper presents an energy flow visualization tool that combines the well-accepted practice of scale modeling in performance venue acoustics design and recent advances in sensor technology to provide rapid and accurate real-time maps of intensity flows derived from simultaneously-measured pressure and velocity quantities in the studied space.

Theory of space-time supermodes in planar multimode waveguides.

When an optical pulse is focused into a multimode waveguide or fiber, the energy is divided among the available guided modes. Consequently, the initially localized intensity spreads transversely, the spatial profile undergoes rapid variations with axial propagation, and the pulse disperses temporally. Space-time (ST) supermodes are pulsed guided field configurations that propagate invariantly in multimode waveguides by assigning each mode to a prescribed wavelength. ST supermodes can be thus viewed as spectrally discrete, guided-wave counterparts of the recently demonstrated propagation-invariant ST wave packets in free space. The group velocity of an ST supermode is tunable independently-in principle-of the waveguide structure, group-velocity dispersion is eliminated or dramatically curtailed, and the time-averaged intensity profile is axially invariant along the waveguide in absence of mode-coupling. We establish here a theoretical framework for studying ST supermodes in planar waveguides. Modal engineering allows sculpting this axially invariant transverse intensity profile from an on-axis peak or dip (dark beam) to a multi-peak or flat distribution. Moreover, ST supermodes can be synthesized using spectrally incoherent light, thus paving the way to potential applications in optical beam delivery for lighting applications.

Drag Reduction Performance of Triangular (V-groove) Riblets with Different Adjacent Height Ratios

Surface structure is used to interfere with the turbulent boundary layer in the groove drag reduction, which is important to the endurance and stability of high-speed and ultrahigh-speed aircraft. The size of the groove structure directly affects the flow in the turbulent boundary layer and changes the drag reduction effect. The drag reduction characteristics of bionic triangular (V-groove) riblets were studied through Particle Image Velocimetry (PIV) experiment and Finite Volume Method (FVM) simulation. Triangular riblets with adjacent height ratios (AHR) of 1.00, 1.74, and 3.02 were considered in this research, and the influence of these groove structures on the flow characteristics of turbulence near the wall is compared with those of the smooth plates. The distribution of time-averaged velocity, turbulence intensity, and coherent structures of turbulent boundary layer on the riblet surface is analyzed to document the effects of the geometric parameters of various groove structures on drag reduction rates. Results showed that the best drag reduction is obtained using the V-groove riblets with adjacent height ratio of 1:1 under the low free-stream velocity. The results can be used as a reference for further optimization of drag reduction structures with surface grooves.

The Fifth Bioelectronic Medicine Summit Hosted by the Feinstein Institutes for Medical Research (Manhasset, NY) and Columbia Engineering (NY, NY) at The Garden City Hotel, Garden City, NY 11530 on October 11-12th, 2022- Bioelectronic Medicine: Today’s Tools, Tomorrow’s Therapies

The Fifth Bioelectronic Medicine Summit Hosted by the Feinstein Institutes for Medical Research (Manhasset, NY) and Columbia Engineering (NY, NY) at The Garden City Hotel, Garden City, NY 11530 on October 11-12th, 2022- Bioelectronic Medicine: Today’s Tools, Tomorrow’s Therapies

Experimental study of instantaneous sound intensities in rectangular enclosures

Instantaneous and time-averaged intensities are relevant field quantities in architectural acoustics investigations. Modeling of intensity flows in coupled volumes and the effect of absorptive material on its trajectory in reverberation chambers have been studied recently. This work focuses on vortical energy flows with a derivation of instantaneous intensity in enclosed spaces and an experimental effort for investigating the changes over time in all field quantities of interest—instantaneous intensity, pressure, and velocity simultaneously. In this study, the scale modeling technique is applied to investigate instantaneous intensity flows experimentally measured using pressure-3D velocity sensors in a rectangular room. Experimental results suggest the presence of vortical intensity modes at specific frequencies correlated to the room dimensions. The resulting simulation of intensity vortices has potential applications in the acoustical design and analysis of complex room geometries where sound energy flows play a major role in the acoustics of the space such as that of coupled-volume spaces and small rooms for critical listening.

Broadband pulses in shear wave elastography

Usually pulses used for shear wave elastography and ARFI are considered to be monochromatic; however, there are advantages to using broadband pulses and including the absorption characteristics of the tissues. A new broadband formulation for volume acoustic radiation forces is presented that accounts for the pulse shape and the changes it encounters propagating through tissues with frequency power law absorption properties. This equation reduces to the well know formulation for the continuous wave case derived by W. Nyborg. Ideal tone bursts employed in elastography have the same time average intensity tissue as continuous wave intensities, irrespective of length. Tone bursts in viscous media have turn-on and turn-off transients called “precursors” and “postcursors,” which can increase pulse amplitudes at the ends of the pulses [Szabo, JASA 45(1): 124–130 (1969)]. By accounting for absorption across a broader bandwidth pulse spectrum, these transient effects can be reduced. Their effects and the potential for pulse shaping are discussed.

Reflective acoustic jet from a mesoscale concave mirror

An acoustic jet (AJ) is similar to a photonic nanojet (PNJ) in achieving high-intensity and sub-wavelength scale focus. Herein, we numerically investigate a reflective acoustic jet (r-AJ) generated by a mesoscale concave mirror using the finite element method. A sub-λ/2 rotational symmetric r-AJ can be produced by an air-filled polylactic acid (PLA) spherical concave mirror immersed in water under a plane acoustic wave. And the properties of r-AJ affected by the concave angle of the mirror are also presented. By combining a PLA spherical structure with the concave mirror, a sub-λ/3 near-field r-AJ can be achieved. We also present the streamlines of the time-averaged acoustic intensity vectors near the r-AJ and the influence of the structural loss of the designed PLA mirror on the r-AJs. The influences of the incident frequency change and PLA properties change on the r-AJs generation and the slight angle between the incoming field and the mirror are presented. Finally, we numerically discuss the potential application of our designed mirror in direct sound printing.

Coherent superposition of the Laguerre-Gaussian beams with different wavelengths: colored optical vortices

We calculate the topological charge (TC) of a coherent axial superposition of different-"color" Laguerre-Gaussian (LG) beams, each having a different wavelength and TC. It is found that the TC of such a superposition is equal to the TC of the longer-wavelength constituent LG beam regardless of the weight coefficient of this beam in the superposition and its corresponding TC. It is interesting that the instantaneous TC of such a superposition is conserved and the (time-averaged) intensity distribution of the "colored" optical vortex changes its light "gamut": whereas in the near field with increasing radius, colors of the light rings (rainbow) change according to their TC in the superposition from the smaller TC to the larger one, upon free-space propagation (to the far field), with increasing radius, the ring colors in the rainbow get arranged in the reverse order from the larger TC to the smaller one. It is also shown that choosing the wavelengths (blue, green, and red)in a special way in a three-color superposition of single-ringed LG beams allows obtaining a time-averaged white light ring at a certain distance.