In this study, a practical and comprehensive experimental technique has been proposed to investigate the interlayer interference characteristics in multilayer tight sandstone gas reservoirs with multi-pressure systems and different reserves. Firstly, single-layer depletion simulation experiments were conducted to measure the gas flow rate and gas extraction efficiency for each of the six layers. A series of physical simulation experiments were then conducted to monitor gas production and pressure variations in commingled multilayer production scenarios under various conditions. Finally, interlayer interference characteristics and gas extraction efficiencies and the main controlling factors were evaluated, analyzed, and identified. The interlayer pressure differential is found to be the primary factor dictating both interference and gas production, followed by initial gas production rates, and permeability variations in the order of positive significance. A higher interlayer pressure differential, a lower initial gas production rate, and a larger permeability variation result in an increase in interlayer interference and a reduction in gas production during commingled production. Increasing the number of commingled layers leads to an overall increase in gas production losses of 10.95% for two layers to 13.35% for four layers. Layers exhibiting small interlayer pressure difference are positively compatible for commingled production.
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