Tibial Nerve Entrapment Research Articles

An overview of exertional leg pain in the athlete

Exertional leg pain is a common problem in the athletic population, presenting with a constellation of similar symptoms. Delayed or incorrect diagnosis and treatment may result in significant morbidity and avoidable cessation of activity. Multiple causes such as chronic exertional compartment syndrome (CECS), medial tibial stress syndrome (MTSS), nerve or vascular entrapment syndromes may be responsible. A thorough history and focused clinical examination is mandated, and may yield clues as to the definitive diagnosis. Investigative adjuncts include imaging, compartment pressure measurement and electrodiagnostic studies. Whilst specific management depends on the underlying cause, the mainstay of initial management is activity modification, with surgery reserved for those who fail to respond to conservative measures.

Novel Therapeutic Approach for Tibial Nerve Entrapment in Chronic Heel Pain Diagnosed as Plantar Fasciitis: A Case Report

Novel Therapeutic Approach for Tibial Nerve Entrapment in Chronic Heel Pain Diagnosed as Plantar Fasciitis: A Case Report

The natural history of tarsal tunnel syndrome in diabetic subjects

Tibial nerve entrapment is highly prevalent in diabetic subjects, resulting in significantly more neuropathic complaints and concomitant sensory disturbances. The study aim was to assess the impact of tarsal tunnel syndrome (TTS) and sensory loss at baseline on incident diabetic foot ulceration (DFU) in diabetic patients, since decompressing the tibial nerve might change the natural history of the disease. In this study, 113 subjects with TTS (69 bilateral, 23 left-sided and 21 right-sided) participating in the prospective Rotterdam Diabetic Foot Study were compared to 303 diabetic controls without TTS, regarding incident DFU. Kaplan-Meier analysis and Cox's regression analysis were used to determine the independent hazard of baseline variables for new DFU. The median observation period was 836.5 days (IQR, 459-1077.8). In bilateral TTS, 17.4% (95% CI: 8.4-26.3%) of subjects experienced DFU versus 8.3% (95% CI: 5.1-11.6%) in controls (left or right) during follow-up (p = 0.0036). In left-sided TTS, no subjects versus 6.2% (95% CI: 3.4-9.0%) in controls had DFUs (p = 0.243). Incident ulceration was seen in 14.3% (95% CI: -0.7% to -29.3%) of right-sided TTS subjects versus 4.1% (95% CI: 1.5-6.3%) in controls (p = 0.034). Besides HbA1c, diminished sensation at the hallux independently increased the risk of ulceration, in patients with (HR: 4.692, p = 0.003) and without (HR: 2.307, p = 0.002) prior DFU. Elevated sensory thresholds in TTS render diabetic patients at a higher risk for DFU. With effective surgery, TTS is likely to be an amenable factor to potentially prevent diabetic foot disease and thereby reduce amputation risk. II.

Tarsal tunnel syndrome: Anatomical facts and clinical implications

Introduction: Tarsal tunnel syndrome (TTS) associates with the posterior tibial nerve (PTN) entrapment at the medial side of the ankle. TTS is a major cause of heel pain. The diagnosis and treatments have several techniques. For accurate diagnosis and effective treatment, the surgeons need to have detailed anatomical knowledge of the arrangement of PTN. The aim of this present study is to describe anatomical aspects and TTS including its etiology, diagnosis, and treatments. Material and Methods: This literature review was done by searching the data from the following databases such as PubMed, Google Scholar, Springer, Elsevier (ScienceDirect), and book chapter. Results: This literature review showed anatomical variations of the PTN and its branches that used the malleolar-calcaneal axis for measurement of branching point. Moreover, these studies showed the origin and the number of branches. The diagnosis of TTS can be used numerous techniques such as neurophysiology, electromyography (EMG), ultrasound scanning (US), and magnetic resonance imaging. The treatment for TTS includes conservative approach, open surgery, and endoscopic procedures. Discussion and Conclusion: The anatomical knowledge of the neurovascular structures at the medial side of the ankle is not only considered for diagnostic purposes but also it ensures safe and effective operative procedures. This literature review will be beneficial for academics and clinicians.

Validity of the Tinel Sign and Prevalence of Tibial Nerve Entrapment at the Tarsal Tunnel in Both Diabetic and Nondiabetic Subjects: A Cross-Sectional Study.

Nerve entrapments like carpal tunnel syndrome are more prevalent in patients with diabetes, especially in those with diabetic polyneuropathy. Our study aims were to investigate the validity of the Tinel sign in diagnosing tibial neuropathy and determine the prevalence of tibial nerve entrapment in both a diabetic and nondiabetic population. Two hundred forty nonneuropathic subjects with diabetes and 176 diabetic subjects with neuropathy participating in the prospective Rotterdam Diabetic Foot Study and 196 reference subjects without diabetes and without neuropathy complaints were evaluated. All subjects underwent sensory testing of the feet, and complaints were assessed using the Michigan Neuropathy Screening Instrument. The Tinel sign was defined as discriminative and valid for diagnosing tibial nerve entrapment when the nerve-related Michigan Neuropathy Screening Instrument subscore of neuropathic symptoms differed at least 5 percent between the Tinel-positive and Tinel-negative subjects. When the sign was valid, prevalence estimates of tibial nerve entrapment at the tarsal tunnel were calculated. Significantly more neuropathic symptoms (p < 0.002) and higher sensory thresholds (p < 0.0005) were observed in (compressed) tibial nerve-innervated areas, indicating that a positive Tinel sign at the tarsal tunnel is a valid measure of tibial nerve abnormality. The prevalence of tibial nerve entrapment in diabetic patients was 44.9 percent (95 percent CI, 40.1 to 49.7 percent) versus 26.5 percent (95 percent CI, 20.3 to 32.7 percent) in healthy controls (p < 0.0001). Tibial nerve entrapment is more prevalent in diabetic subjects than in controls. The significantly more frequently reported neuropathic complaints and concomitant sensory disturbances provide evidence for the role of superimposed entrapment neuropathy in diabetes-related neuropathy. Diagnostic, IV.

A Study Of Soleus Muscle Clinical and Embryological consideration

Objectives – Soleus is a multipennate muscle of back of leg taking origin from tibia and fibula as a single belly. It inserts on calcaneum as Achilles tendon and acts as a plantar flexor of foot. Aim of the study was to find variations in origin,insertion ,nerve supply and number of muscle bellies of soleus Material and methods– 50 lower limbs were meticulously dissected to observe variations in soleus muscle Results - 8 % limbs showed accessory head of soleus. 4 heads,3 heads and 2 heads of soleus were observed. Variations of tibial nerve while supplying the accessory heads were noted. Conclusion – Symptomatic cases with accessory soleus have presented in athletes. Due to sedentary lifestyle most of the cases are passing unnoticed.Cases of neurovascular entrapment and clubfoot deformity have required surgical intervention. Knowledge of variations of soleus will be of prime importance during diagnostic procedures. Key words – Accessory head of soleus, Tibial nerve entrapment, Achilles tendon, Supernumerary head of soleus and Soleus secundus.

Diagnostic Ultrasound of the Soleal Sling

The soleal sling may be a site of tibial nerve entrapment. Objective diagnosis of this syndrome is difficult with current nerve conduction study techniques, magnetic resonance imaging, and neurosensory testing. Diagnostic ultrasound is ideally suited to visualize the tibial nerve statically and dynamically as it enters the soleal sling, thus making an objective diagnosis of soleal sling impingement much easier.

Bakers Cyst: A Case Report and its clinical significance

The Bakers or Popliteal cyst is a bursa seen between medial head Gastrocnemius and Semimembranosus. This bursa when present usually communicates with the cavity of Knee joint, most of the times being asymptomatic. They can occur due to any intra-articular pathology including bony inflammation, cartilaginous lesions, meniscal or ligament tear, etc. The symptomatic cases are mainly leading to pressure effects due to anatomical vulnerability of surrounding structures. Symptoms related to Popliteal vein compression and Tibial nerve entrapment are the most common clinical presentations. Although, Bakers cyst is a chronic disorder and after treatment also requires follow up to prevent relapses, it causes difficulty in differential diagnosis while presenting in acute state. Ultrasonographic examination and Magnetic Resonance Imaging are important tool to avoid misdiagnosis and inappropriate treatment. Surgical resection of the cyst is rarely indicated when intra-articular pathology cannot be diagnosed or its treatment is not responding.

Prostaglandin E1 alleviates neuropathic pain and neural dysfunction from entrapment neuropathy associated with diabetes mellitus

In this report, we present the results of investigation of the effects of prostaglandin E1 (PGE1) on entrapment neuropathy using a diabetic rat. A total of 60 male Sprague-Dawley rats were used in the study. The model of tibial nerve entrapment neuropathy associated with diabetes mellitus was created by streptozotocin-induced diabetic rats reared in cages with wire grid flooring. Rats were assigned to four groups: nondiabetic (n = 15), untreated diabetic (n = 15), diabetic treated with 30 μg/kg PGE1 (n = 15), and diabetic treated with 100 μg/kg PGE1 (n = 15). Pain tests and electrophysiological tests were performed at 0, 2, and 4 weeks, and assessments of gait, histology, and mRNA expression levels were performed at 4 weeks after initiating the PGE1 administration. In the 30 and 100 μg groups, the mechanical withdrawal thresholds measured by pain tests at 4 weeks (36.2 ± 16.4 g and 31.7 ± 15.3 g, respectively) and the motor conduction velocity (24.0 ± 0.2 m/s and 24.4 ± 0.3 m/s, respectively) were significantly higher than the untreated diabetic group (all P < 0.05) and lower than the nondiabetic group (all P < 0.001). In the gait analysis, the mean intensities in the 30 and 100 μg group (128.0 ± 20.1 a.u. and 109.0 ± 27.8 a.u., respectively) were significantly higher than the untreated diabetic (P < 0.01) and were not significantly different from the nondiabetic group (P = 0.81). Fiber density (P = 0.46) and fiber diameter (P = 0.15) did not show any significant differences. PGE1 significantly decreased nerve growth factor (NGF) mRNA and increased vascular endothelial growth factor (VEGF) mRNA in the tibial nerve (both P < 0.01). In conclusion, neurological deteriorations of diabetic rats were alleviated with PGE1, which is associated with inhibition of NGF and enhancement of VEGF at the entrapment site.

Entrapment of the Lateral Plantar Nerve Distal to the Tarsal Tunnel: A Case Report

Tibial nerve entrapment is a common cause of foot pain. Identifying the location of the entrapment may be difficult. This case report describes the electrodiagnosis of the lateral plantar nerve branch of the tibial nerve in a 50 year-old woman who failed to respond to the local steroid injection for plantar fasciitis and subsequently a tarsal tunnel release. The etiology of the nerve entrapment is discussed as well as the role of electrodiagnostic studies to locate the nerve entrapment. This case highlights the role of meticulous clinical evaluation and electrodiagnosis for the diagnosis of this challenging condition and a simple in-office treatment to reduce patient’s symptoms.

MR Neurography Findings of Soleal Sling Entrapment

The ever-increasing use of higher field strength (3 T) scanners and novel pulse sequences with improved spatial resolution and signal-to-noise ratio have rendered MR neurography (MRN) a valuable technique in the assessment of peripheral neuropathies. The aim of this study is to illustrate the imaging findings of high-resolution MRN in patients who suffer from tibial nerve entrapment due to a soleal fibromuscular sling and to correlate the imaging findings with intraoperative and clinical examination results. This article depicts the surgically confirmed imaging findings of high-resolution MRN in tibial nerve entrapment by the soleal sling.

Clinical utility of tibial motor and sensory nerve conduction studies with motor recording from the flexor hallucis brevis: a methodological and reliability study

BackgroundStandard tibial motor nerve conduction measures are established with recording from the abductor hallucis. This technique is often technically challenging and clinicians have difficulty interpreting the information particularly in the short segment needed to assess focal tibial nerve entrapment at the medial ankle as occurs in posterior tarsal tunnel syndrome. The flexor hallucis brevis (FHB) has been described as an alternative site for recording tibial nerve function in those with posterior tarsal tunnel syndrome. Normative data has not been established for this technique. This pilot study describes the technique in detail. In addition we provide reference values for medial and lateral plantar orthodromic sensory measures and assessed intrarater reliability for all measures.MethodsEighty healthy female participants took part, and 39 returned for serial testing at 4 time points. Mean values ± SD were recorded for nerve conduction measures, and coefficient of variation as well as intraclass correlation coefficients (ICC) were calculated.ResultsMotor latency, amplitude and velocity values for the FHB were 4.1 ± 0.9 msec, 8.0 ± 3.0 mV and 45.6 ± 3.4 m/s, respectively. Sensory latencies, amplitudes, and velocities, respectively, were 2.8 ± 0.3 msec, 26.7 ± 10.1 μV, and 41.4 ± 3.5 m/s for the medial plantar nerve and 3.2 ± 0.5 msec, 13.3 ± 4.7 μV, and 44.3 ± 4.0 msec for the lateral plantar nerve. All values demonstrated significant ICC values (P ≤ 0.007).ConclusionMotor recording from the FHB provides technically clear waveforms that allow for an improved ability to assess tibial nerve function in the short segments used to assess tarsal tunnel syndrome. The reported means will begin to establish normal values for this technique.

Soft tissue chondroma compression—A unique cause of tarsal tunnel syndrome: A case report and review of the literature

Posterior tibial nerve entrapment can be caused by extrinsic compression in the tarsal tunnel. We report a nerve compression due to a chondroma in the tarsal tunnel. To our knowledge it is a very rare cause of tarsal tunnel syndrome.

Effect of Foot and Ankle Position on Tarsal Tunnel Compartment Volume

Tarsal tunnel pressure is increased when the foot and ankle are positioned in eversion or inversion from neutral, aggravating symptoms of tarsal tunnel syndrome in some patients. Space-occupying lesions may cause tarsal tunnel syndrome. We hypothesized that positional change of the foot and ankle from neutral to eversion or inversion causes decreased tarsal tunnel compartment volume that may aggravate symptoms of posterior tibial nerve entrapment. MRI of 13 ankles in nine healthy subjects in three positions (neutral, eversion, inversion) were obtained with respect to the malleolar-calcaneal plane; this plane was defined by the distal tip of the anterior colliculus of the medial malleolus, the medial tubercle of the posterior calcaneal tuberosity, and the lateral tubercle of the posterior calcaneal tuberosity. The borders of the tarsal tunnel noted on the MRI were traced with a computer digitizing apparatus to determine the cross-sectional area of the tarsal tunnel on each image, and the slice thickness and interspace distance for the seven central images were used to calculate tarsal tunnel volume. The mean tarsal tunnel volume was significantly greater when the foot and ankle were in neutral position (21.5 +/- 0.9 cm(3)) than in either full eversion (18.0 +/- 0.9 cm(3); p = or < 0.001) or inversion (20.3 +/- 1.0 cm(3); p = or < 0.001). The results support the hypothesis that eversion and inversion of the foot and ankle cause decreased compartment volume of the tarsal tunnel and increased tarsal tunnel pressure that may contribute to symptoms of posterior tibial nerve entrapment in tarsal tunnel syndrome. Neutral immobilization of the foot and ankle may relieve symptoms of posterior tibial nerve entrapment in tarsal tunnel syndrome by minimizing pressure on the nerve and maximizing tarsal tunnel compartment volume available for the nerve.

A Baker's Cyst Causing Common Peroneal Nerve and Tibial Nerve Entrapment Neuropathy: A Case Report

Degenerative disc disease of the lumbar spine caused leg pain with associated calf weakness and atrophy. However, an unusual case of leg pain and calf atrophy due to neural compression is reported. We reported a rare case of a Baker's cyst causing common peroneal nerve and tibial nerve entrapment neuropathy. Initially, after arthroscopic menisectomy and cyst decompression, Baker's cyst was recurred and then open excision was done. Until 1 year after surgery, the cyst was not recurred, increased muscle bulk was noted and EMG showed improved findings. But she continued to complain of lower leg weakness and sole paresthesia owing to delayed diagnosis and cyst decompression.

Tibial nerve entrapment in the popliteal fossa

Details are presented of nine cases of tibial nerve entrapment by the tendinous arch of origin of the soleus muscle. The diagnosis was confirmed by surgical exploration of the popliteal fossa in six patients, who recovered fully after division of the soleus arch, whereas the other three improved spontaneously. This condition can be distinguished clinically from tibial nerve compression at the ankle, and from S1 radiculopathy, by the presence of severe pain and tenderness and a positive Tinel sign in the popliteal fossa, and by electrodiagnostic studies. © 2000 John Wiley & Sons, Inc. Muscle Nerve 23: 1883–1886, 2000

Tibial nerve entrapment in the popliteal fossa.

Details are presented of nine cases of tibial nerve entrapment by the tendinous arch of origin of the soleus muscle. The diagnosis was confirmed by surgical exploration of the popliteal fossa in six patients, who recovered fully after division of the soleus arch, whereas the other three improved spontaneously. This condition can be distinguished clinically from tibial nerve compression at the ankle, and from S1 radiculopathy, by the presence of severe pain and tenderness and a positive Tinel sign in the popliteal fossa, and by electrodiagnostic studies.

Effect of Foot and Ankle Position on Tarsal Tunnel Compartment Pressure

Tarsal tunnel intracompartment pressures were determined in 10 fresh-frozen normal human adult cadaver specimens. With the foot and ankle held in mild plantarflexion and neutral eversion-inversion, mean tarsal tunnel pressure was minimal (2 +/- 1 mmHg). However, when the foot and ankle were positioned in full eversion, mean tarsal tunnel pressure increased to 32 +/- 5 mmHg (P < or = 0.005); in full inversion, mean pressure increased to 17 +/- 5 mmHg (P < or = 0.05). There was no significant difference in mean tarsal tunnel pressure between the everted and inverted positions. These results support the hypothesis that increased pressure within the tarsal tunnel when the foot is moved into the everted or inverted position may aggravate posterior tibial nerve entrapment. These findings may also provide an explanation for clinically observed aggravation of symptoms in these positions, night pain, and improvement of symptoms with neutral immobilization in some patients with tarsal tunnel syndrome.

The Pseudoradicular Syndrome: A Case Report Implicating Double Crush Mechanisms in Peripheral Nerve Tissue of the Lower Extremity

“Double Crush Syndrome” is a condition in which proximal compression of a nerve decreases the ability of that nerve to withstand compression at a distal site. No studies have been done on the relationship between lumbar spine dysfunction and concomitant lower extremity peripheral nerve entrapments in regards to physical therapy management. The case report concerns a 32 year old male runner who presented with a physician's diagnosis of lumbar radiculopathy, with a request to rule out plantar fasciitis. This report describes extraneural and intraneural tissue mobilization techniques in the evaluation and treatment of a coexisting lumbar spine dysfunction and posterior tibial nerve entrapment. An explanation of the double crush syndrome as a possible mechanism in this lumbar pseudoradicular presentation is advanced. This report illustrates the importance of addressing both neural entrapment sites in the successful treatment of this condition.

Posterior tibial neuropathy from ruptured baker's cyst

Objectives: To increase awareness of entrapment neuropathy caused by rupture of Baker's cyst. Methods: A patient with psoriatic arthritis, ruptured Baker's cyst, and entrapment neuropathy is reported and the literature on this complication is reviewed. Results: Nerve entrapment caused by rupture of Baker's cyst is rare. Neurologicalexamination and demonstration of Baker's cyst by Color Doppler Duplex Ultrasound (CDDU) help in making the diagnosis. Nerve Conduction Study (NCS) may confirm the diagnosis of posterior tibial nerve entrapment. Conclusions: Peripheral nerve entrapment should be considered in patientswith Baker's cysts and loss of sensation along the plantar aspect of the foot or other neurological symptoms or findings.