This paper investigates a plasmonic toroidal metasurface cancer cell sensor capable of highly sensitive, cost-effective, and label-free detection. Utilizing titanium and gold split ring resonators, the metasurface unit are formed. Numerical findings indicate a significant resonance frequency shift of the metasurface upon changes in the measured substance, enabling accurate detection of various cancer cell types, such as blood cancer cell and cervical cancer cell in the 2.5 THz-4.5 THz band, with sensitivity reaching 1.075 THz/RIU. Moreover, the metasurface sensor demonstrates superior angular stability and high sensitivity in detecting cyanide and heavy metal-contaminated water. These research outcomes lay a theoretical foundation for the development and application of highly sensitive cancer cell sensors.