Papillary Carcinoma In Thyroglossal Duct Cyst Research Articles

Thyroglossal duct cyst papillary carcinoma with lymphatic infiltration: A case report

Thyroglossal duct cyst papillary carcinoma with lymphatic infiltration: A case report

Thyroglossal Duct Cyst Papillary Carcinoma: A Case Report and Review of the Literature

Thyroglossal Duct Cyst Papillary Carcinoma: A Case Report and Review of the Literature

Papillary Carcinoma of Thyroglossal Cyst with Thyroid Hemiagenesis: Is Conservative Surgical Management Enough?

We describe a case of papillary carcinoma in a thyroglossal cyst with left hemiagenesis of the thyroid gland in a 24-year-old female patient. We opted not to perform a total thyroidectomy as the patient was at low risk for aggressive disease. In this article we review the criteria for selection of thyroidectomy in incidentally discovered papillary carcinomas after thyroglossal cyst excision and management protocol in case of coexisting thyroid hemi-agenesis. To our knowledge, this case represents the second case report of an association between left thyroid hemiagenesis and thyroglossal duct cyst papillary carcinoma.

Thyroglossal duct cyst papillary carcinoma: A treatment puzzle yet to be solved!

Thyroglossal duct cyst (TGDC) is the most common congenital aberration of the thyroid gland. On the contrary, TGDC malignancies are rare events constituting

Thyroglossal duct cyst papillary carcinoma: case report and review of literature

Thyroglossal duct cyst papillary carcinoma: case report and review of literature

Primary thyroglossal duct cyst papillary carcinoma. Case report and literature review

Aim: Primary papillary carcinoma in a thyroglossal duct cyst (PTGDPC) is a rare pathological condition diagnosed in only 1–2% of the cases of midline neck cysts. Diagnosis is most commonly made postoperatively after the cyst is dissected by Sistrunk’s operation. There is a lot of controversy over the definitive management of PTGDPC and the proper therapeutic approach to it especially when we consider using total thyroidectomy and subsequent adjuvant radioiodine therapy in the treatment. We report a case of papillary carcinoma in a thyroglossal duct cyst and review the relevant literature to clarify what algorithm should a clinician apply in such cases. Materials and methods: We present a case of a 38-year-old woman with papillary carcinoma arising from a cyst in ductus thyroglossus which was histologically identified after Sistrunk’s operation. We discuss also the pathogenesis of papillary carcinoma in a thyroglossal duct cyst and the need to perform thyroidectomy. Results: The patient (T. C.) was a 38-year-old woman hospitalized in the Clinic of Otorhinolaryngology at St. George University Hospital in Plovdiv with a diagnosis of midline neck cyst confirmed by neck computed tomography and ultrasound. Sistrunk’s procedure was used for the patient who was shown by postoperative histology and repeat verification to have papillary carcinoma. The patient’s thyroid was examined scintigraphically yielding inconclusive evidence for neoplasm and then removed by thyroidectomy. No synchronous papillary carcinoma in the thyroid gland was identified. The histology showed nodular colloid goitre. The patient received postoperatively radioactive iodine (I-131) therapy and hormone-replacement therapy with L-thyroxin. Conclusions: We have found total thyroidectomy to be rather controversial approach to managing papillary carcinoma in a thyroglossal duct cyst. Accurate identification of a possible primary focal area in the thyroid gland followed by total thyroidectomy in conjunction with I-131 ablation and hormone replacement therapy seem far more appropriate in such cases.

Does Papillary Carcinoma of Thyroglossal Duct Cyst Develop De Novo?

Backround. Thyroglossal duct cyst (TDC) is a developmental abnormality of the thyroid gland. Due to embryological remnants of thyroid tissue located in the TDC, the same malignant tumors that develop in the thyroid gland can also develop in the TDC. Methods. We present the unique case of a 39-year-old female with simultaneous de novo papillary carcinoma in a TDC and the thyroid gland. Results. With the suspicion of simultaneous papillary carcinoma in the TDC and the thyroid gland, Sistrunk procedure with total thyroidectomy and central neck exploration was performed. Conclusion. The clinician should have a high index of suspicion upon encountering papillary carcinoma of the TDC to differentiate de novo papillary carcinoma in the TDC from those originating from the thyroid gland, because papillary carcinoma in TDC may originate from an occult thyroid papillary carcinoma.

Papillary Carcinoma in Thyroglossal Cyst

ABSTRACTThyroglossal duct cysts are not uncommon but malignancy in such a cyst is infrequent. Two patients of thyroglossal duct cyst papillary carcinoma are presented here. Both of these patients had different risk profiles and were managed differently. Both the patients have been followed up for 5 years and have shown no recurrences.How to cite this articleKhaund G, Agarwal V, Barman S, Baruah D, Gogoi B. Papillary Carcinoma in Thyroglossal Cyst. Int J Phonosurg Laryngol 2014;4(2):69-70.

Primary thyroglossal duct cyst papillary carcinoma with cervical node metastasis

Primary thyroglossal duct cyst papillary carcinoma with cervical node metastasis

Papillary carcinoma of the thyroglossal duct cyst: A tertiary healthcare centre experience

Although thyroglossal duct cyst (TDC) is a common problem, papillary carcinoma is a very rare finding. The management detail and protocol is yet to be well defined. This paper aims to highlight the experience of King Abdulaziz University Hospital in papillary carcinoma of TDC in the past five years. Four patients out of 315 patients reviewed retrospectively were diagnosed to have papillary carcinoma of the TDC. Fifty per cent had involvement of the thyroid. One patient (25%) was a child. Conclusion: Papillary carcinoma of TDC has a favorable prognosis if managed properly by an experienced team.

Invasive thyroglossal duct cyst papillary carcinoma: a case report

IntroductionA thyroglossal duct cyst is the most common congenital anomaly of the thyroid gland and midline masses in childhood (70% abnormality in childhood, 7% in adult). Carcinomas arising from a thyroglossal duct cyst are rare (only 1% of thyroglossal duct cyst cases) and characterized by relatively non-aggressive behavior and rare lymphatic spread. They are also diagnosed mostly during the third and fourth decades of life. About 85% to 92% of all thyroglossal duct cyst carcinomas are papillary carcinomas.Case presentationWe present the case of a 44-year-old Iranian woman with Cacausian ethnicity with a painless anterior neck mass that appeared gradually over three months. She had a history of frequent painful swelling of the anterior part of her neck, which subsided with antibiotic therapy. Thyroid functional tests were normal and a thyroid scinitigraphy showed a cold nodule in the left lobe of her thyroid. A computed tomography scan revealed a large, heterogeneous enhancing soft tissue mass with cystic components in the midline of the anterior neck space. This extended from the base of the tongue,(completely separated from its muscles, to the inferior aspect of the thyroid gland and showed the destruction of the hyoid bone and the thyroid cartilage. The diagnosis of a thyroglossal duct cyst with malignant transformation was maintained. A fine needle aspiration revealed papillary carcinoma.ConclusionThis patient's case is presented because of its rare, aggressive, and invasive nature and rare and unusual manifestation, as well as its rapid increase in size, the destruction of the hyoid bone, chondrolysis of the thyroid cartilage, lymph adenopathy and the existence of a cold nodule in the thyroid gland.