Three-dimensional Mathematical Model Research Articles

Molecular dynamics simulations of a multicellular model with cell-cell interactions and Hippo signaling pathway.

The transcriptional coactivator Yes-associated protein (YAP)/transcriptional co-activator with PDZ binding motif (TAZ) induces cell proliferation through nuclear localization at low cell density. Conversely, at extremely high cell density, the Hippo pathway, which regulates YAP/TAZ, is activated. This activation leads to the translocation of YAP/TAZ into the cytoplasm, resulting in cell cycle arrest. Various cancer cells have several times more YAP/TAZ than normal cells. However, it is not entirely clear whether this several-fold increase in YAP/TAZ alone is sufficient to overcome proliferation inhibition (contact inhibition) under high-density conditions, thereby allowing continuous proliferation. In this study, we construct a three-dimensional (3D) mathematical model of cell proliferation incorporating the Hippo-YAP/TAZ pathway. Herein, a significant innovation in our approach is the introduction of a novel modeling component that inputs cell density, which reflects cell dynamics, into the Hippo pathway and enables the simulation of cell proliferation as the output response. We assume such 3D model with cell-cell interactions by solving reaction and molecular dynamics (MD) equations by applying adhesion and repulsive forces that act between cells and frictional forces acting on each cell. We assume Lennard-Jones (12-6) potential with a softcore character so that each cell secures its exclusive domain. We set cell cycles composed of mitotic and cell growth phases in which cells divide and grow under the influence of cell kinetics. We perform mathematical simulations at various YAP/TAZ levels to investigate the extent of YAP/TAZ increase required for sustained proliferation at high density. The results show that a twofold increase in YAP/TAZ levels of cancer cells was sufficient to evade cell cycle arrest compared to normal cells, enabling cells to continue proliferating even under high-density conditions. Finally, this mathematical model, which incorporates cell-cell interactions and the Hippo-YAP/TAZ pathway, may be applicable for evaluating cancer malignancy based on YAP/TAZ levels, developing drugs to suppress the abnormal proliferation of cancer cells, and determining appropriate drug dosages. The source codes are freely available.

Design optimization for enhancing performances of integrated planar inductor for power electronics applications

Goal. In this work, the performance of an integrated planar inductor with a square geometric shape using different materials for the substrate: Ni-Fe, Mn-Zn and Ni-Zn have been analyzed and investigated in order to assess the impact of the substrate material on the performance of the integrated planar inductor and to determine the optimal material in the various applications of power modules in power electronics. Methods. To this end, we carried out an in-depth analysis of the geometric dimensions of the integrated planar inductor, by calculating all the geometric parameters of the proposed structure, to establish an equivalent physical model of the integrated planar inductor in order to evaluate its different electrical specifications. The numerical simulation, based on the three-dimensional mathematical model of the system using Maxwell’s equations, was realized by COMSOL Multiphysics software. Results show the importance of the substrate material for the performance of the integrated planar inductor, and specify that the use of Ni-Fe ferrite as a substrate of the integrated planar inductor gives very interesting performance compared to other materials studied. The presented results provide valuable information on the influence of substrate material on the performance of embedded integrated planar inductor and can help to design and optimize these components for use in power electronic systems. Practical value. These results are significant for a wide range of applications, where the integrated planar inductor performance and efficiency can have a significant impact on the overall performance and cost-effectiveness of the power electronic device. References 37, tables 2, figures 7.

ON THE CHAOTIC NATURE OF A CAPUTO FRACTIONAL MATHEMATICAL MODEL OF CANCER AND ITS CROSSOVER BEHAVIORS

In this paper, a three-dimensional mathematical model of cancer, incorporating tumor cells, host normal cells, and effector immune cells, is examined. The chaotic nature of this cancer model is explored within the framework of Caputo fractional calculus. The analysis employs local stability assessment using the Matignon criteria, Lyapunov exponents (LEs) for various fractional orders of derivatives, bifurcation plots reflecting changes in the fractional derivative order, simulation outcomes of a novel chaotic attractor, Kaplan–Yorke dimension, and sensitivity to initial conditions. The results demonstrate that the Caputo fractional cancer model exhibits chaotic behavior for selected parameters. Moreover, the fractional derivative orders significantly influence the extent of chaotic behavior. Specifically, as the fractional derivative order increases from zero to one, the intensity of chaos diminishes, evidenced by a decrease in both the LE and the Kaplan–Yorke dimension. A piecewise modeling approach is applied to the cancer model, incorporating deterministic, stochastic, and power-law behaviors. Three distinct scenarios are developed within this framework, revealing several novel crossover behaviors through simulation. Notably, it is observed that when cancer dynamics initially follow a power-law behavior and subsequently transition into a stochastic process, the disease dynamics can stabilize, suggesting a positive outlook for disease control. Conversely, if the cancer dynamics begin with a deterministic process and then shift to a stochastic process, the system may enter a chaotic state, complicating disease management efforts.

Study of Flow and Zinc Dross Removal in Hot-Dip Galvanizing with Combined Traveling Magnetic Field

The removal of zinc dross, which continuously generates and partially floats on a molten zinc surface, has been a persistent challenge during hot-dip galvanizing. Herein, a three-dimensional mathematical model coupled with the electromagnetic field, flow field and air-knife jet flow was established to investigate the flow and zinc dross removal in a zinc pot. Two types of traveling magnetic field combined modes (Mode 1 and Mode 2) were compared. The surface dross removal efficiency was introduced to evaluate the ability of the zinc flow field to compel the movement of zinc dross. The research findings indicate that, in comparison to the influence of strip steel line speed, both the electromagnetic field and air-knife jet have a more pronounced effect on altering the flow characteristics of a molten zinc at surface. The dross removal efficiency for Mode 1 is much far superior to that of Mode 2. With an increase in the driving current, the dross removal efficiency increases while the excessive driving current cannot promote the dross removal efficiency significantly.

Removal and distribution behaviors of inclusion particles in the steel melt under different rotation modes during continuous casting

This work investigated the removal and distribution behaviors of non-metallic inclusion particles caused by the flow of molten steel under two rotational modes, i.e. from edge to center (E-C) and from center to edge (C-E). Three-dimensional mathematical models discovering the relation between fluid flow, temperature distribution, solidified shell growth of large round bloom, and the movement of inclusions were established to investigate the mechanism of the differences. The obtained results show that under the C-E rotational mode, the removal rate of inclusions is 7 times and the highest local agglomeration number density of inclusions is reduced by 38.4 % compared to the E-C rotational mode. The current work proposes that the C-E rotating flow of molten steel can effectively raise the removal and uniform distribution of inclusions, thereby providing a new strategy for effective control of inclusion during the continuous casting process utilizing the novel electromagnetic metallurgy.

Stress-strain state of an intraosseous dental implant under stress under unfavorable biomechanical conditions

Biomechanical conditions affect the stress-strain state of teeth, dentures, implants and surrounding tissues, however, some biomechanical processes in implants and covering prosthetic structures have not been sufficiently studied under different operating conditions. The purpose of the study. А comparative analysis of the maximum stresses in titanium implants, abutments and covering ceramic crowns under different biomechanical operating conditions. Material and methods. Three-dimensional mathematical modeling of the stress-strain state of the implant, abutment, crown was carried out using the SolidWork computer program in a model of an implant immersed in a segment of the mandible and covered with a ceramic crown. Load conditions: vertical or inclined 45° with a value of 150 N. Well-known indicators of the physical and mechanical properties of fabrics and structural materials were used. Adverse biomechanical conditions were simulated: a 30% reduction in the length, diameter, length and diameter of the implant; an abutment slope of 15° and 30°; bone resorption by 30% and 50%; increased load by 30%; occlusive supracontact; contact with bone tissue by 50% (immediate load). Results and discussions. In comparison with optimal biomechanical conditions, the stresses in the implant and the covering crown increase under vertical and inclined loads only with an increase in load and the presence of occlusive supracontact. An increase in stresses only in the implant occurs with a decrease in the diameter of the implant, a combined decrease in the diameter and length of the implant, with an abutment tilt, resorption of periimplant bone tissue, incomplete contact of the implant with bone tissue under immediate load. Stress reduction in the implant and the covering crown occurs when the length of the implant decreases. Conclusions. Unfavorable biomechanical conditions in most cases lead to an increase in stresses in the implant, especially with inclined loading; the decrease in stresses in the implant with a decrease in the length of the implant is most likely due to an increase in stresses in the surrounding bone tissue.

Model order reduction and sensitivity analysis for complex heat transfer simulations inside the human eyeball.

Heat transfer in the human eyeball, a complex organ, is significantly influenced by various pathophysiological and external parameters. Particularly, heat transfer critically affects fluid behavior within the eye and ocular drug delivery processes. Overcoming the challenges of experimental analysis, this study introduces a comprehensive three-dimensional mathematical and computational model to simulate the heat transfer in a realistic geometry. Our work includes an extensive sensitivity analysis to address uncertainties and delineate the impact of different variables on heat distribution in ocular tissues. To manage the model's complexity, we employed a very fast model reduction technique with certified sharp error bounds, ensuring computational efficiency without compromising accuracy. Our results demonstrate remarkable consistency with experimental observations and align closely with existing numerical findings in the literature. Crucially, our findings underscore the significant role of blood flow and environmental conditions, particularly in the eye's internal tissues. Clinically, this model offers a promising tool for examining the temperature-related effects of various therapeutic interventions on the eye. Such insights are invaluable for optimizing treatment strategies in ophthalmology.

Atmospheric pressure-induced three-dimensional surface wave propagation in the compressible ocean: Effect of static compression

Under the assumptions of linearized water wave theory, we build a three-dimensional mathematical model that couples atmospheric pressure waves and surface ocean waves, including water compressibility and its static part, to simulate Meteotsunami propagation in the ocean. The solution uses the Laplace–Fourier double transformation technique, emphasizing axisymmetry of the mathematical problem and rigorous treatment of a fairly complicated dispersion relation while using inverse transformations. A novel derivation of the axisymmetric atmospheric pressure front is shown. The impact of water compressibility is shown through a comparative graphical representation against the incompressible case. Faster travel of free-surface waves is observed in the incompressible ocean, followed by the cases with and without static compression of the compressible ocean, respectively. The static compression shifts the phase of the acoustic-gravity modes. The locked wave is hardly influenced by the water compressibility and is entangled with the moving pressure front. The model is validated with the observational pressure data and agrees well with our computed pressure profile. Then, the locked wave profile generated from our model agrees well with the deep-ocean assessment and reporting of tsunami data.

Devising a calculation method for modern structures of current-conducting elements in large electric machines in a three-dimensional statement

The jumpers of rotor pole-to-pole connections are highly stressed elements in a hydraulic generator structure. These assemblies often fail due to deformation that exceeds the size of an air gap. Existing methods do not take into account the thermal component and attempts to improve the design are not based on mathematical models that make it possible to perform calculations with an accuracy of more than 50 %. The method devised in this work makes it possible to obtain boundary conditions of the third kind on the basis of three-dimensional mathematical modeling of the ventilation system of the hydraulic unit without simplifications. The method accuracy is explained by taking into account the spatial thermal component. The heat transfer coefficient determined by this method in the pole-to-pole connections area was ~250 W/(m2·K). Using FEM, mathematical modeling of the thermal stress state of pole-to-pole connections was carried out, taking into account mechanical and thermal factors. This made it possible to design the improved connection structure with additional fastening elements, which make it possible to reduce the displacement to 0.03 mm, and the stress to 53 MPa at the rotor rotation frequency of 880 rpm. This design makes it possible to enable reliable operation of the hydraulic unit under the condition of increasing the rotor rotation frequency to overspeed with disconnected combinatorial dependence, provided that the actual stresses are 0.95 % of the material yield strength. The convergence of the values obtained by the proposed method and by the HSS method exceeded 99 %. The practical result is the proposals for the hydraulic generator design modernization

Numerical investigation on heat transfer and pressure drop characteristics of Micro-Pillar array surface

The array surface structure can improve heat transfer efficiency and achieve large heat transfer area per unit of volume. In this study, a numerical simulation using CFD method was carried out to construct a dual-channel three-dimensional mathematical model with micro-pillar array surface. The characteristic of heat transfer and flow resistance for the arrayed surface structure have been studied. In addition, four different array configurations, including cylindrical, elliptical, quadrangular and herringbone, were considered to compare the thermal performance and flow behavior. The configuration with the best overall performance was obtained as cylindrical by comparison. The effects of different heights, arrangement methods and pitches on the system performance were analyzed. The velocity distribution on the array surface was also obtained. It is found that the cylindrical array structure has obvious advantages in overall performance, with more uniform surface velocity distribution and better overall performance at lower Re conditions.

The effect of lateral intake slope on sedimentation transport

Generally, The problem of sediments at the entrances to subsidiary channels is considered one of the most common problems for which water resources engineers seek to find appropriate solutions, as it causes significant damage to hydraulic installations, as the accumulation of these sediments in the canal rollers over time leads to the collapse of those channels, which results in many losses. In this study, a three-dimensional mathematical model was developed using the Ansys Fluent CFD program, and this model was matched with previous laboratory experiments, as this mathematical model showed clear accuracy and consistency. Work was done on changing the geometry of the sub-channel and studying the effect of changing the inclination of the sub-channel on reducing the amount of sediment entering the channel or not, since the channel used in this study is 2 m. Adjustments were made to the inclination of the canal in two different forms: The first is to make the first half (1 m) of the canal horizontal, and the inclination begins in the second half, at three different angles, namely 15, 30, and 45 degrees. The other form is to change the inclination along the total length of the sub-channel (2 m) with the same effect. Angles 15, 30 and 45. The results showed the ineffectiveness of changing the inclination of the sub-channel from the middle of the distance, while the results of changing the total inclination were different. It is possible that the slope angle of 45 is considered the best in terms of increasing the speed and clearly reducing the area of the separation zone and the erosion zone.

Исследование процессов тепломассопереноса в нефтяной скважине с~призабойным нагревателем различной длины

This paper considers a three-dimensional mathematical model of heat and mass transfer in an oil well with a bottom-hole heater. The vertical section of an oil well with an electric bottom-hole heater device for wells with highly viscous and paraffinic oil was investigated. The bottomhole heater is a monolithic cylinder located in the lower part of the tubing. The tubing contains perforations through which the oil fluid enters the tubing. The use of a local heater in the near-wellbore area makes it possible to increase the temperature of the fluid flowing through it, thereby reducing the viscosity of the oil and the load on the electric centrifugal pump, for which the critical value of the viscosity of the pumped medium is determined. The implementation of this model was carried out by the finite volume method using the ANSYS engineering simulation software. The geometry of finite elements and the finite volume mesh generated, an analogue of a continuous computational domain, were constructed by the MESH preprocessor. The finite volume mesh consists of polyhedral elements. Using the model, the fields of temperature, velocity and viscosity were obtained throughout the entire volume of the area under study. The curves showing the dependence of the average temperature of the cross section on the longitudinal coordinate of the tubing and the dependence of the average temperature at the inlet to an electric centrifugal pump on the heater power are presented. The viscosity value at the maximum permissible temperature of the heater, as well as the value of sufficient heater power to ensure uninterrupted pumping of petroleum liquid, were determined. The results obtained can be used to significantly improve the operating efficiency of an electric centrifugal pump, to increase the turnaround time and to reduce material costs during field development.

Effect of cleaning parameters on the molten pool shape and molten slag dynamics in the corner scarfing process of the casting slab

In the steel industry, improving the hot charging and heat delivery ratio in the continuous casting of slabs and thick slabs can effectively reduce carbon emissions, lower energy consumption, and improve production efficiency. However, this puts very strict requirements on the surface quality of continuous-casting slab. Flame scarfing (or cleaning) technology is currently an important process in the metallurgy field, which can effectively remove impurities and crack defects on the surface and corners of continuous casting slab to ensure the quality and performance of the final product. Under the action of cleaning flame and iron oxide reaction heat, a cleaning molten pool is formed in the corner of the casting slab, and the shape and depth of the molten pool have an important influence on the cleaning effect. A three-dimensional mathematical model is developed to study the effect of slab cleaning speed and oxygen flow rate on the shape of the molten pool in the corners for the corner flame cleaning process. Simultaneously, a two-phase flow volume of fluid (VOF) model for gas-slag interactions is employed to examine the motion behavior of the molten slag. The results showed that when the operating conditions changed, the cleaning speed increased by 1 m/min, the length of the wide and narrow sides decreased by approximately 9.2 mm, and the depth of the corner pool decreased by approximately 5.3 mm. Moreover, a slag-blocking device was designed to mitigate the issue of slag splashing effectively based on the numerical simulation results compared with and without the slag-blocking device. These study works provide beneficial theoretical support and practical guidance for refining and optimizing flame-cleaning techniques.

Numerical and experimental studies on the heat transfer characteristics and process optimization of the billet soaking furnace

The precision of furnace temperature control in the soaking furnace is critical to the quality of billet heating. This paper develops a three-dimensional(3D) mathematical model of the heating process of steel billets in the soaking furnace, which can be monitored online in real time. The accuracy of the model was verified by black-box experiments. A comparative analysis of the model’s simulated and experimental data revealed a hit rate exceeding 70 % (with a relative error margin within ± 5 %). Leveraging this mathematical model, we propose a direct optimization strategy that effectively saves 24 % of heating time, accelerates the process of achieving temperature uniformity within the billet, and boosts overall heating effectiveness. This approach offers potential for broader application in optimizing the heating processes of various materials.

Analysis of the sintering process of the sintering charge in a high layer. Report 1. Fuel combustion and dissociation of limestone

Communication 1 provides a brief overview of theoretical works on the creation of mathematical models of the sintering process, ranging from simplified balance models to the three-dimensional dynamic model. A modern three-dimensional mathematical model is adapted from industrial data on the agglomeration of a sinter mix in a bed 700 mm high with a bed of sinter at the sinter plant No. 5 of PJSC “MMK”. Changes in the device circuit diagram of sinter plan, the actual temperature of the mix, segregation of fuel along the height of the bed, the mode of intensive ignition of the mix in the ignition hearth with diffusion burners, the unevenness of the sintering process across the width of the pallets, additional heating of the bed after the hearth with air from a linear cooler, the actual degree of throttling of the vacuum chambers of the sinter machine, heat exchange in pallets are taken into account. The process of a combustion zone of solid fuel formation under the ignition hearth has been analyzed, and an increase in its height during the sintering process in a high bed has been established, that due to the segregation of mix and fuel along the height of the bed and the consumption of oxygen for the oxidation of FeO above this zone. The processes of limestone dissociation and melting of the mix zones formation and their development during the sintering process are considered

Analysis of the sintering process of the sintering charge in a high layer. Report 2. Reduction and oxidation processes, moisture behavior and gas dynamics of the sintering process

Piece of information 1 of this article briefly examines the history of the development of modeling the sintering process. To study it, a modern three-dimensional mathematical model was used. Its adaptation was made for the operating conditions of sinter plant No. 5 of PJSC “MMK”, on whose sinter machines the mix is sintered in a bed 700 mm high. Studies have been carried out on the formation and development of fuel combustion and limestone dissociation zones. In the information under consideration, the reduction and oxidation processes of moving the temperature fields of the material with the melt, the combustion zone, processes of gas formation along the height of the bed are presented together. It has been established that a small-height Fe2O3 reduction zone is formed under the fuel combustion zone, and that the conditions for the formation of an oxidation zone under the fuel combustion zone, discussed in the literature, are extremely unfavorable. An analysis of the processes of drying and waterlogging of the mix in a high bed was carried out. A lesser negative impact of moisture condensation in a high bed has been established compared to a low or medium height bed. The gas-dynamic operation of the bed under the ignition hearth with throttling conditions of the first vacuum chambers of the sinter machine is considered. A decrease in the rate of gas filtration at the outlet of the bed was established in comparison with the input rate after the drying and fuel combustion zones exited the bed.

Evolution mechanism and interaction of the muzzle combustion-gas jets field of underwater dual-barrel synchronized launch

Despite a certain amount of research that has been done on the muzzle combustion–gas jet field of underwater launching in recent years, there are still few reports on the evolution mechanism and interaction of underwater dual-barrel synchronised launch flow fields. To fill this gap, this study aimed to numerically analyse the effects of different barrel intervals on the transient jet field evolution characteristics of the dual-barrel launch. The three-dimensional unsteady multi-phase mathematical model was created and compared with an underwater sealed emission experiment of data for verification. The volume of fluid multi-phase flow model is used to describe the gas–liquid two-phase flow process, and the k–ε turbulence model simulates the turbulent mixing phenomenon in the jet field. On this basis, the user-defined function coupling internal ballistics process was used to determine the transient jet field of a double-barrelled, 30 mm (d = 30) underwater artillery numerically at the barrel intervals of 3d, 4d and 5d. The calculation results indicate that the closer the interval is, the more chaotic the pressure field is, and the Mach disc structure forms later. When the barrel interval is 3d, the Mach disc formation time is ∼ 0.2 ms, while it forms at ∼ 0.15 ms when the barrel interval is 5d. The movement law of projectiles in water is consistent with the change of Mach disc displacement with time, and both satisfy the exponential growth law. The velocity field core is elliptical, and the vortices on both sides of the muzzle continue to grow within 0.4 ms when the launch interval is 3d. As the barrel interval increases, the core of the velocity field is bottle-shaped, the vortex on both sides of the muzzle increases first and then decreases within 0.4 ms, and the maximum temperature of the flow field increases by 15 %.

MODELLING OF MASS TRANSFER IN WASTEWATER FACILITIES

Problem statement. The design of wastewater treatment systems is a complex process and requires the use of special mathematical models. As a rule, empirical models are used at the stage of designing structures of water drainage systems, which allow obtaining only an “integral” characteristic of the efficiency of wastewater treatment. But in a number of cases, it is important to have information about the spatial distribution of the impurity concentration in the structure. To solve this problem, you need to have three-dimensional mathematical models. In the future, there is a shortage of such models, so the creation of three-dimensional multifactorial models for the analysis of the efficiency of drainage system structures is an urgent task. The purpose of the article. Development of a three-dimensional numerical model for the analysis of the mass transfer process to determine the impurity concentration in the clarifier. Methodology. The analysis of impurity concentration fields in the clarifier is carried out by numerical integration of the three-dimensional equation for the velocity potential and the three-dimensional equation of the convective-diffusion transport of the impurity. For the numerical integration of the Laplace equation for the velocity potential, the variable-triangular method and the Liebmann method are used. Finite-difference splitting schemes are used for numerical integration of the three-dimensional equation of convective-diffusion transport of impurities. Scientific novelty. A dynamic multifactorial numerical model was created for the analysis of the process of mass transfer of impurities in a settling tank by conducting a computational experiment. Practical value. The built multifactorial numerical model makes it possible to analyze the efficiency of wastewater treatment in clarifiers that have a complex geometric shape and cannot be calculated on the basis of existing engineering methods. Conclusions. On the basis of the developed three-dimensional numerical model, a computer code was created, which allows you to quickly obtain information about the distribution of the impurity concentration in the settling tank.

Research on Genetic Algorithm Optimization with Fusion Tabu Search Strategy and Its Application in Solving Three-Dimensional Packing Problems

Symmetry is an important principle and characteristic that is prevalent in nature and artificial environments. In the three-dimensional packing problem, leveraging the inherent symmetry of goods and the symmetry of the packing space can enhance packing efficiency and utilization.The three-dimensional packing problem is an NP-hard combinatorial optimization problem in the field of modern logistics, with high computational complexity. This paper proposes an improved genetic algorithm by incorporating a fusion tabu search strategy to address this problem. The algorithm employs a three-dimensional loading mathematical model and utilizes a wall-building method under residual space constraints for stacking goods. Furthermore, adaptation of fitness variation strategy, chromosome adjustment, and tabu search algorithm are introduced to balance the algorithm’s global and local search capabilities, as well as to enhance population diversity and convergence speed. Through testing on benchmark cases such as Bischoff and Ratcliff, the improved algorithm demonstrates an average increase of over 3% in packing space utilization compared to traditional genetic algorithms and other heuristic algorithms, validating its feasibility and effectiveness. The proposed improved genetic algorithm provides new insights for solving three-dimensional packing problems and optimizing logistics loading schedules, offering promising prospects for various applications.

Magnetotelluric Observations in the Caspian Sea

Abstract —To study the geological structure in the search for raw hydrocarbons within the Volga delta and the Caspian Sea, two intersecting profiles of magnetotelluric sounding were performed. The analysis of geoelectric sections based on the one-dimensional inversion of the initial and normalized invariant curves of apparent resistance showed that it is necessary to use methods of three-dimensional mathematical modeling to form reliable geoelectric models. Their initial construction necessary for the three-dimensional interpretation of invariant apparent resistance curves was carried out taking into account their one-dimensional inversion. The resulting model, including the lower structural part, is constructed by the method of interactive matching to the apparent resistance curves of model curves calculated according to the program of three-dimensional mathematical modeling. This approach made it possible to take into account the influence of local galvanic distortions on the apparent resistance curves when evaluating the distribution of electrical conductivity in the lower parts of the subsea deposits. As a result of the integrated interpretation of magnetotelluric data, blocks with increased conductivity have been identified in the subsea deposits of the Northern Caspian Sea, which are most likely associated with high fluid saturation of Cretaceous and Neogene sediments. Their position correlates with the regional discontinuous structures of the region.