Thoughtful Strategy Research Articles

СОВРЕМЕННЫЕ ПОДХОДЫ К ТРАНСФОРМАЦИИ ПОТРЕБИТЕЛЬСКОГО ПОВЕДЕНИЯ РАБОТНИКОВ УГОЛЬНОЙ ОТРАСЛИ НА РЫНКЕ МЕДИЦИНСКИХ И ФАРМАЦЕВТИЧЕСКИХ ТОВАРОВ И УСЛУГ

In modern conditions, for pharmacy, as an integral part of healthcare, new concepts and technologies of pharmaceutical services and, in general, pharmaceutical care, aimed at consumers of medicines of different categories and professional groups, have become a powerful incentive for further development. Important importance in working with consumers of medical and pharmaceutical goods and services is attached to marketing research of consumer behavior; the study of preferences in the selection of goods factors influencing the decision to purchase. Of particular importance is the consumer behavior of modern pharmacy customers, which is changing due to an imbalance between the state of the pharmacy system's customer base and existing methods of customer counseling. There is a need to focus on different segments of consumers, each of which requires specific client technologies that contribute to the transformation of consumer behavior from "standard" to individual, corresponding to the status, mentality, financial capabilities, level of information literacy, typology of the buyer. Studying the assessments and opinions of respondents helps to identify patterns in consumer behavior and makes it possible to develop a more thoughtful strategy for information and advisory work with employees of the coal industry, paying special attention to issues of pharmaceutical consulting, information, attentive service, the use of new forms and methods of work that would increase consumer interest in purchasing effective and safe medicines. The consumer's decision-making process is considered, as a rule, as part of the following stages: consumer awareness of the problem, information search, evaluation and selection of purchase alternatives, purchase, use of purchase and evaluation of the solution. The factors of consumer behavior or purchasing decisions in relation to the buyer are conditionally divided into internal and external. Pharmaceutical organizations that sell medicines seek to influence consumer behavior by building their activities based on the concept of marketing. Knowledge of the basics of marketing is necessary to manage consumer behavior in the market.

Synthesis of novel heteroatom-rich bis-Schiff base for enhancing performance of multi-walled carbon nanotube/polyaniline nanocatalyst in oxygen evolution reaction

Fabrication of oxygen evolution electrocatalysts with high performance and endurance is of interest for the electrolysis of water. To date, several compounds have been introduced to achieve it but the idea of using bis-Schiff base with conductive materials/noble metal may be a thoughtful strategy. Herein, bis-Schiff base of 6,6′ ((oxybis(4,1phenylene)) bis (azanylylidene)) bis (methanylylidene) bis (3-(2-(2- hydroxyethoxy) ethoxy) phenol) (HBIEP) was prepared and used as a modifier for the preparation of an electrocatalyst. A highly efficient electrocatalyst is reported based on HBIEP deposited on Au nanoparticles (NPs) and hollow hierarchical polyaniline (PANI) nanorod/multi-walled carbon nanotube (MWCNT) to accelerate the electron transfer rate and enhance the chemical stability for oxygen evolution reaction (OER). The MWCNT/PANI/HBIEP/Au exhibits high current density for OER at low overpotential and provides low Tafel slope of 35 mV dec−1 and remarkable stability during 50 h. Electrochemical impedance spectroscopy showed that in comparison to MWCNT/PANI, the presence of both AuNPs and HBIEP can further facilitate the charge transfer and improve the performance of the electrocatalyst for OER. Although MWCNT/PANI/Au presents proper performance, HBIEP enhances its efficiency and stability during OER. The suitable functionality of the electrocatalyst comes from its electronic structure and large active sites which improved in the presence of bis-Schiff base.

Residents Forum: Cruising Through the Final Barrier…

The postgraduate final year exam is another milestone set to adorn the degree of a qualified resident. Covering the vast syllabus during residency can be a tough challenge. Thoughtful strategy and well-planned tactics pave the way for a successful outcome. This article aims to provide a few guiding points for the last-minute preparation to ace the final barrier.

Network-supported and adaptable binding efficacy for flexible and multi-functionalized chitosan/phenolic carbaldehyde hydrogels

A thoughtful strategy has been intended to control the hydrogel networking to assess the binding efficacy of multifunctional hydrogel. The processing of two distinct network-supported hydrogels has portrayed to express the operating interactions involved during co-existence with solvents, small molecules, biomolecules, etc. Herein, chitosan has separately functionalized in semisynthetic approaches with 4-hydroxyisopthalaldehyde (ChDA) and 2-hydroxybenzene-1,3,5-tricarbaldehyde (ChTA) to construct different gel networks. The disposition of gel networks ChDA adapts more flexible chain or spine, whereas ChTA possesses restricted movements within gel networks. The gel networks of hydrogels have a significant role in their distinct physical activities. Their gel-bonding elucidations have performed to establish the variation in mechanical, swelling photophysical properties, etc. Remarkable self-fluorescence behaviors are used as a tool for binding study. Distinctive gel networks and their flexibility have investigated against self-fluorescence, UV–Vis, and FTIR against small molecule, Boron trifluoride and biomolecule, and Bovine serum albumin. Hydrogel/BF3 shows variation in fluorescence due to the disposition of gel networks. Hydrogel/BSA quenching of fluorescence at three different temperatures provides the binding constant and Stern-Volmer quenching constant. Theoretical DFT and docking studies successfully established the flexibility against binding study. The controlling of cross-linking or functionalization is very crucial for the development of hydrogel-mediated applications.

Optimization of ion/electron channels enabled by multiscale MXene aerogel for integrated self-healable flexible energy storage and electronic skin system

MXenes have received extensive attention in the fields of energy storage and flexible electronics due to their excellent physicochemical properties. However, MXenes are prone to self-stacking, which would result in severely degraded performance of the electronic devices. Unlike the optimization of the structure-property relationship of MXene at specific scale in most reported studies, the current work is based on the multiscale design concept: MXene aerogels with abundant ion/electron channels are constructed through an efficient chemical oxidation and rapid gas foaming strategy. Nanoscale in-plane nanoporous MXenes can lead to increased ion channels and effectively shortened ion transport distances. Micron-scale MXene aerogels can provide abundant ionic active sites and maximized electron channels. The fabricated integrated self-healable flexible zinc-ion energy storage and pressure sensing system offers high areal specific capacitance of 576 mF cm−2, sufficient energy density of 156.8 uWh cm−2 at a power density of 4200 uW cm−2, and ultra-high pressure sensitivity (1024.9 kPa−1), which has great potential in applications including self-healing and flexible wearable devices. The multiscale design concept achieves the maximization of ion/electron channels, realizing a thoughtful strategy for the optimization of flexible electronic devices.

Effects of Online Teaching during the COVID-19 Pandemic on Nursing Students’ Intention to Join the Nursing Workforce: A Cross-Sectional Study

Nursing education programs were interrupted and largely moved online as a result of the COVID-19 pandemic. The purpose of this study was to explore Taiwanese nursing students’ perspectives on online teaching during the COVID-19 pandemic and whether changes in teaching models have affected their intention to join the nursing workforce. A multi-center cross-sectional survey was conducted. Nursing students at universities and those at 5-year junior colleges were recruited to participate in the study. Data were collected through an online questionnaire survey. A total of 687 students responded to the questionnaire. The results were analyzed using percentages, mean ranks, and nonparametric methods. The results showed that 78.6% of the students agreed that online teaching was more flexible; most students stated that technical problems with computer equipment and stability of the network were large challenges that impeded online teaching. Furthermore, up to 64.8% of the students considered that online courses had affected their preparations for future nursing jobs, especially in terms of a lack of proficiency in nursing skills and inadequacy in actual interactions with patients. Online teaching is a powerful tool for nursing education, but a thoughtful strategy and more proactive approach are necessary to overcome the existing challenges for online teaching.

Considerations When Transitioning From Health-System Pharmacy Administration and Leadership Resident to Pharmacy Leader.

A key part to assimilating into an organization in a leadership role is managing transitions. Health-System Pharmacy Administration and Leadership (HSPAL) Residency Programs focus on laying the foundation for continued growth in management and leadership skills. This article focuses on keys for transitioning from HSPAL Pharmacy Resident to Pharmacy Leader. Managing transitions is and will continue to be an important topic for all leaders. As HSPAL Residents transition to new pharmacy leaders, understanding pharmacy practice building relationships, maintaining them, and having a thoughtful strategy through this transition will allow for a more complete understanding of the organization to navigate complexities, develop people, and complete projects and initiatives. While this article is specific to HSPAL residents, these concepts can apply to the transition to pharmacy leaders.

Demonstration of an Analytic Process using Home Health Care Electronic Health Records: A Case Example Exploring the Prevalence of Patients with a Substance Use History and a Venous Access Device

Electronic health records (EHR) are an important, but underutilized source for home health care research and practice improvement. Although the use of EHR is more efficient than prospective data collection, an analysis of EHR data can be complex and time-consuming. To demonstrate the overall process, we describe a secondary analysis of EHR data that explored the prevalence of home health care patients with a substance use history (SUH) and a venous access device (VAD). We detail our process of EHR data extraction, management, and analysis to assist researchers and clinicians interested in similar work. The example analysis showed that that 10.6% of adult home health care patients had a SUH, 8.8% had a long-term VAD, and 1.3% had both. EHRs can be a valuable data source for home health care research and quality improvement projects, but a systematic and thoughtful strategy is needed to fully leverage their potential.

A framework to guide planetary health education

A framework to guide planetary health education

Chitosan/gelatin hydrogel and endometrial stem cells with subsequent atorvastatin injection impact in regenerating spinal cord tissue

Central nervous system trauma can cause loss of functional sensory neurons and motor functions that results in death of neuronal cells and axon degeneration. For this purpose, therapeutic approaches to enhance repair mechanisms spinal cord injury (SCI) is reflected to be a difficult task that requires thoughtful strategy. Hydrogel scaffolds in the presence of stem cells could repair damaged SCI due to their ability to support cellular viability, motility, and differentiation. In this study, we investigated the effectiveness of a biomimetic composite hydrogel of chitosan and gelatin containing endometrial stem cells (EnSCs) as a minimally invasive treatment of SCI in an animal model. Moreover, the simultaneous, effect of intraperitoneal injection of atorvastatin drug was assessed for animal models. From the results, morphological and cell viability studies demonstrated favorable seeding microenvironment and viability in the hydrogel. The transplanted hydrogel containing EnSCs into hemisected SCI rats showed recovery of sensory and motor functions by confirming locomotor activity evaluation using Basso, Beattie, and Bresnahan test. The growth of neuronal cells confirmed with immunohistochemical study. The findings in this study suggested that combination therapy using biomimetic hydrogel seeded with stem cells as well as atorvastatin injection has the potential to heal SCI through neuroinflammation attenuation, improvement of functional recovery, and limit the secondary damages.

Exit strategies for wildlife conservation: why they are rare and why every institution needs one

Exit strategies – plans to end involvement in a project once selected criteria have been reached – are rare in conservation planning but can play a vital role in the conservation planning process; such strategies also prepare the institution, its staff, its partners, and a wider group of stakeholders for eventual success or failure and signal when it is time to move on. Exit strategies may indicate that the project has been terminated but may also signal success, or that project leadership has transitioned to another, more appropriate entity. We address why exit strategies are uncommon in conservation, why they are essential, what determines when to transition or leave, and how to plan for circumstances afterwards. A good exit strategy addresses financial and legal liabilities to employees, publication of results, and ownership of data, among other things. A comprehensive, thoughtful strategy can lead to “beautiful exits” that minimize negative consequences to the project.

Expression Orale: Amérique Du Nord by Michèle Barféty et al.

Reviewed by: Expression Orale: Amérique Du Nord by Michèle Barféty et al. Shannon Becker Barféty, Michèle, Patricia Beaujoin, Fabien Olivry, et Denis Liakin. Expression orale: Amérique du Nord. CLE International, 2019. ISBN 978-2-09-035176-7. Pp. 128. Part of the Compétences series, Expression orale is intended for students at the B1 level according to the Common European Framework of Reference for Languages, which corresponds to approximately the Intermediate Mid to Advanced Low level in ACTFL standards. It is important to note that this book is intended for learners who will be communicating with speakers of Québécois French. The book is divided into five units, each containing three lessons and followed by a quiz called a "bilan." The lessons are divided into sections called "imiter," "interpréter," and "s'exprimer," a thoughtful strategy that allows the learner to progress from exercises centered on identification and repetition, to answering open-ended questions based on written and oral prompts, and finally to text-based discussions leading to a debate. Importantly, Expression orale maintains a focus on communication throughout, only addressing grammar in boxes of "outils" that provide students with important sentences and phrases that they can incorporate into their production. Among other tasks, learners are asked to verify oral comprehension, to repeat dialogues, to use clues to guess the context of dialogues, to exchange information, and to role play based on visual and audio prompts. This culminates in reading a text, answering discussion questions, and preparing a debate with classmates. After each unit, learners complete the bilan, a brief quiz worth 25 points containing only two exercises: one that requires them to fill in the blanks of a written dialogue using the various outils, or grammatical structures, from the preceding lesson, and one that asks them to fill in the blanks of a short text using words from a provided list of vocabulary. A particularly interesting activity, which appears only in the first bilan and is thereafter replaced by the text completion task, asks learners to read a sentence and decide which of three sentences below it is the best reformulation, i.e., containing the same information and synonyms of key words. Native speaker dialogues are used throughout the book, with audio files available online and transcripts in the back of the book. The quality of the dialogue recordings is high, and the speakers articulate clearly and at an appropriate speed for this level of learner. It is easy to imagine using elements of this book even beyond a conversation course, for example in a survey course to introduce learners to Québécois French. Visually, the format of the chapters is easy to follow, with clearly delineated sections and "outils" boxes that stand out from the text, and numerous pictures throughout. [End Page 201] Shannon Becker Northern Illinois University Copyright © 2020 American Association of Teachers of French

Fabrication of carbon dots@restricted access molecularly imprinted polymers for selective detection of metronidazole in serum

A custom-tailored design was proposed for the fabrication of carbon dots coupled with restricted access materials and molecularly imprinted polymers (CDs@RAM-MIPs) to detect metronidazole (MNZ). Biomass carbon dots (CDs) were derived from longan peels assisted with high pressure microwave, and had the merits of eco-friendly, excellent photostability and low toxicity. In this work, glycidyl methacrylate was used as a co-polymeric monomer to increase hydroxyl groups on the surface of synthetic materials, which eliminated the interference of biological macromolecules. The specific binding cavities of CDs@RAM-MIPs were formed after removing the template molecule (MNZ). The obtained CDs@RAM-MIPs can selectively capture MNZ through the specific interaction between recognition sites and MNZ, and obey photoinduced electron transfer fluorescence quenching mechanism. The highly sensitive and selective fluorescent sensor based CDs@RAM-MIPs had a wide linear range (50–1200 ng mL−1) and a low detection limit (17.4 ng mL−1) for MNZ. It has been utilized to detect MNZ in serum with recoveries of 93.5%–102.7%, and the relative standards (RSDs) were 1.9%–3.6%, respectively. This work provides a thoughtful strategy for preparation and application of CDs@RAM-MIPs, which presages its great potential for detecting trace compounds in real samples.

Implementation of BIM Technology into the Design Process Using the Scheme of BIM Execution Plan

Digital Revolution is one of the most up-to-date topics in the construction industry – and not even in that. According to the spreading of a new trend in Building Design, Construction and Facility Management – using of Building Information Modelling Technology and its Management, there are going to be many changes in the way to develop the design process and other phases of building life cycle. BIM Technology use is present in the whole life cycle of buildings and other constructions and is able to connect all participants of building process in effective way. BIM Technology as a new trend in building design reveals the need to set up effective processes, their parts, participants, their responsibilities, goals and the way to reach goals, etc. The main philosophy of BIM Technology’s implementation into the design processes lies in the BIM Execution Plan. This Plan should be specified for specific activities in specific environment and for specific participants in the whole construction process. These processes should be well conceived and managed. That’s way we can undoubtedly replace the “M” in BIM (Modelling) by the “M” as a Management. This paper contributes to the further thoughtful strategy for the specific process of the design – from the designer’s point of view and implementation of BIM Technology into this process in order to make the design process more effective. There are identified possible barriers for this implementation, their main causes, proposal to remove these obstacles and outlined a possible process of effective design using BIM technology and its principles. It is important to realize, that the implementation of BIM Technology in the design process will lead to a better virtual reality of the building and thus its transformation into physical reality will lead to a better construction and allow for greater cost savings not only during construction phase, but also in other phases of the building life cycle, especially during its use.

Reducing Diagnostic Errors Worldwide Through Diagnostic Management Teams.

A major challenge facing most countries is the growing cost of healthcare. Laboratory testing costs constitute approximately 3% of all clinical costs, while waste of funds due to inappropriate admissions to clinical departments is reported to be as high as 15%. A frequently used approach to save money in healthcare is random reduction of laboratory budgets, focusing on decreasing the number of unnecessary laboratory tests. The World Health Assembly has approached this problem by publishing a list of essential in vitro diagnostic tests, to achieve a global rationalization of the problem. A much more thoughtful strategy to reducing healthcare expenditure is to improve the efficiency of the diagnostic process. Decreasing the time to a correct diagnosis provides considerable financial and clinical benefits. Additionally, reducing both overutilization and underutilization of laboratory tests while achieving the correct diagnosis is of great benefit to challenged healthcare budgets. Examining the situation in the United States and Italy, this review presents an opportunity for reducing diagnostic error and increasing the efficiency of diagnostic testing worldwide. One approach taken to achieve major savings in healthcare in the United States, which can be applied in Italy and other countries, is the creation of “diagnostic management teams,” comprising experts in specialty areas of medicine, primarily based in the clinical laboratory, who can advise physicians on the selection of necessary tests and the interpretation of complex test results.

Theoretical and experimental study for the biomimetic recognition of levothyroxine hormone on magnetic molecularly imprinted polymer

This study addresses the rational design of a magnetic molecularly imprinted polymer (magnetic-MIP) for the selective recognition of the hormone levothyroxine. The theoretical study was carried out by the density functional theory (DFT) computations considering dispersion interaction energies, and using the D2 Grimme's correction. The B97-D/def2-SV(P)/PCM method is used not only for studying the structure of the template the and monomer-monomer interactions, but also to assess the stoichiometry, noncovalent binding energies, solvation effects and thermodynamics properties such as binding energy. Among the 13 monomers studied in silico, itaconic acid is the most suitable according to the thermodynamic values. In order to assess the efficiency of the computational study, three different magnetic-MIPs based on itaconic acid, acrylic acid and acrylamide were synthesized and experimentally compared. The theoretical results are in agreement with experimental binding studies based on laser confocal microscopy, magneto-actuated immunoassay and electrochemical sensing. Furthermore, and for the first time, the direct electrochemical sensing of L-thyroxine preconcentrated on magnetic-MIP was successfully performed on magneto-actuated electrodes within 30 min with a limit of detection of as low as 0.0356 ng mL−1 which cover the clinical range of total L-thyroxine. Finally, the main analytical features were compared with the gold standard method based on commercial competitive immunoassays. This work provides a thoughtful strategy for magnetic molecularly imprinted polymer design, synthesis and application, opening new perspectives in the integration of these materials in magneto-actuated approaches for replacing specific antibodies in biosensors and microfluidic devices.

Przestępstwo prania brudnych pieniędzy w ujęciu komparatystycznym. Rozważania porównawczoprawne na tle porządków prawnych wybranych państw europejskich, azjatyckich oraz kontynentu amerykańskiego

The purpose of this paper is to expound the reasons for systematic growth of the money laundering crime, as well as its variations and chosen aspects of the attempt stadial form. Regardless of legal culture perspective, the complex of features required as an element of analyzed offence is, as a rule, comparable or at least similar. Hitherto a numerous of normative regulations at national and supranational level has been presented and implemented. Thoughtful, consistent and intransigent legal strategy of anti-money laundering in different countries (e.g. in the Republic of India or in the People’s Republic of Bangladesh) resulted in a noticeable reduction of the scope of the described practice. Of all the twelve analyzed countries, in the author’s assessment, the best anti-money laundering legal solutions characterized the Kingdom of Norway. Partially, beyond the outstanding substantive law, this favorable position was achieved thanks to mixed character of Norway’s legal culture. In addition, the complex of features of analyzed offence is not too narrow or too wide. In the Norwegian penal code there is no question of superfluous casuistry. On the other side, author contrasted anti-money laundering legislation of the Russian Federation and of the Ukraine. The Russian and Ukrainian legislation in subject of criminal law is erratic, the complex of features required as an element of analyzed offence is too wide and what more, a numerous groups of entities are excluded from the action of specified provisions of positive law. Thus, the Russian Federation is gradually becoming a central entity of European money laundering issue.

Coral Battleground? Re-examining the ‘Save the Reef’ campaign in 1960s Australia

Today’s campaigns to protect the Great Barrier Reef (GBR) have parallels with historical campaigns. With hindsight, we can more clearly see the way environmental discourses are socially constructed as well as their outcomes. This is potentially insightful for contemporary environmentalists. Beginning in 1967, the Save the Reef campaign had a thoughtful media strategy and sought to socially construct the GBR as a precious ecosystem that was at risk from exploitation. Histories of this campaign remember environmentalists as a weak, David-like contender in a fight against the powerful Goliath of the Queensland government and extractive industries. Using the historical archives as our primary data source, however, reveals that these memories are overstated and that environmentalists actually enjoyed widespread support. Moreover, we see that the GBR has no explicit ‘opponents’; even those who sought to exploit it came from a position of pragmatic conservationism, believing exploitation and conservation could coexist. The historical struggle over power and control of the GBR shows the positive outcomes which emerged from broad coalitions, as opposed to an adversarial and combative approach to activism.

Positive Relationships: Behaviour - Once bitten..

A thoughtful strategy will help practitioners keep incidents of biting under control, writes Jennie Lindon.

GFR estimating equations, CKD prevalence and the public health

GFR estimating equations, CKD prevalence and the public health