The article discusses the strength characteristics of masonry with filling vertical and horizontal seams with polymer adhesive paste. The analysis of domestic and foreign publications and sources carried out in this work, including the results of previously performed experiments and field studies, showed the need for additional studies of masonry on thin seams, including using new materials of domestic production. The main purpose of the research is to determine the physical, mechanical and deformation parameters of masonry made of large products with filling seams with new, modern types of materials, the production of which has been mastered at domestic factories. Conducting studies of the physical and mechanical and deformation parameters of masonry on thin seams filled with polymer adhesive paste is important for the correct determination of the design characteristics of such masonry. The current problem requires comprehensive studies of the strength characteristics of masonry on thin seams, including taking into account adhesion.