This paper presents a comprehensive investigation, comprised of analytical, experimental and numerical approaches, into the interaction between the sound field produced within a pressurised air-filled back cavity and the vibration of a thin clamped circular plate subjected to its pressure. Previous investigations into the interaction of sound fields with vibrating boundaries have primarily been restricted to non-pressurised cavities. We extend the application of the weak modal coupling method to derive a solution for this unexplored physical problem by utilising classic plate theory, Fourier-Bessel series formulation and the uncoupled solutions for a pressurised cylindrical sound field and a thin clamped circular plate with uniform radial tension. We describe the vibration response of the coupled system in terms of the uncoupled cavity and plate modes. Using a set of geometric and physical properties for the system, the resonance frequencies and response functions are calculated and the coupling between the sound field and the plate is investigated as a function of cavity pressure, providing novel fundamental insights into the physical system. We construct an experimental rig to embody the conditions of the analytical investigation for the purpose of validation. Finite element analysis (FEA), employing modal analysis and transient dynamic analysis, is used to further validate and extend the analytical insights while more accurately mirroring the experimental conditions. The response functions, mode shapes, resonance frequencies and their dependence on the cavity pressure were experimentally measured and numerically simulated, with direct comparisons made with the analytical model. A high degree of accuracy for the analytical model is validated along with its ability to describe the underlying physical phenomena. The validated analytical model is then leveraged to perform fundamental explorations into the modal contributions as a function of cavity pressure and a parametric sensitivity analysis on the effects of plate radii and plate thickness on the coupled system resonance frequencies.