Thin Cement Mantle Research Articles

Radiographic, Functional, and Oncologic Outcomes of Cemented Modular Proximal Femur Replacement Using the “French Paradox” Technique

BackgroundEndoprostheses are frequently used in the management of tumors involving the proximal femur. Aseptic loosening is a common complication that has been linked to the cementing technique. The “French paradox” is well-known cementing technique in the arthroplasty literature. No previous reports have assessed loosening in proximal femur replacements using this technique. We examined rates of femoral stem aseptic loosening in proximal femur replacements, functional outcomes, complications, and oncologic outcomes. MethodsWe conducted a retrospective review of 47 patients who underwent proximal femur replacement between 2000 and 2019. Two reviewers evaluated preoperative and postoperative radiographs using the International Society of Limb Salvage scoring system and Barrack criteria for stem loosening. The acetabulum was evaluated according to the criteria of Baker et al. Functional outcomes were assessed using Musculoskeletal Tumor Society (MSTS) score and Toronto Extremity Salvage Score. The mean follow-up was 44 months. ResultsThe mean International Society of Limb Salvage scores for the 2 reviewers were 86% ± 6% and 84% ± 6%. The first reviewer graded femoral stem loosening as “possibly loose” in 2 patients, one of whom was graded as possibly loose by the second reviewer. The 2 reviewers found no acetabular erosion in 16 (70%) and 15 (65.4%) patients, respectively. The mean Musculoskeletal Tumor Society score and Toronto Extremity Salvage Score at last follow-up were 61% and 72%, respectively. Twenty complications occurred in 13 patients, and 5 patients experienced local recurrence. ConclusionDespite complications, we showed favorable femoral component survival rates. Cementing the proximal femur prosthesis with tight canal fit and thin cement mantle is a viable option for the short and medium term. Level of EvidenceIII.

Biomechanical behaviour of a French femoral component with thin cement mantle: The 'French paradox' may not be a paradox after all.

ObjectiveCement thickness of at least 2 mm is generally associated with more favorable results for the femoral component in cemented hip arthroplasty. However, French-designed stems have shown favorable outcomes even with thin cement mantle. The biomechanical behaviors of a French stem, Charnley-Marcel-Kerboull (CMK) and cement were researched in this study.MethodsSix polished CMK stems were implanted into a composite femur, and one million times dynamic loading tests were performed. Stem subsidence and the compressive force at the bone-cement interface were measured. Tantalum ball (ball) migration in the cement was analyzed by micro CTResultsThe cement thickness of 95 % of the proximal and middle region was less than 2.5 mm. A small amount of stem subsidence was observed even with collar contact. The greatest compressive force was observed at the proximal medial region and significant positive correlation was observed between stem subsidence and compressive force. 9 of 11 balls in the medial region moved to the horizontal direction more than that of the perpendicular direction. The amount of ball movement distance in the perpendicular direction was 59 to 83% of the stem subsidence, which was thought to be slip in the cement of the stem. No cement defect and no cement breakage were seen.ConclusionThin cement in CMK stems produced effective hoop stress without excessive stem and cement subsidence. Polished CMK stem may work like force-closed fixation in short-term experiment.Cite this article: Y. Numata, A. Kaneuji, L. Kerboull, E. Takahashi, T. Ichiseki, K. Fukui, J. Tsujioka, N. Kawahara. Biomechanical behaviour of a French femoral component with thin cement mantle: The ‘French paradox’ may not be a paradox after all. Bone Joint Res 2018;7:485–493. DOI: 10.1302/2046-3758.77.BJR-2017-0288.R2.

Cement mantle thickness does not influence serum or local gentamicin concentrations in hybrid total hip arthroplasty: a randomised controlled trial.

We investigated the in vivo gentamicin elution kinetics of Hi-Fatigue Gentamicin Bone Cement (AAP Biomaterials GmbH) in serum and drain fluid after hybrid hip arthroplasty and the relationship with cement mantle thickness. We compared in a randomised, non-blinded prospective study, the local and systemic gentamicin concentrations in 2 groups. The thin cement mantle group ( n = 16) received a stem implanted line-to-line with the broach, whereas the thick group ( n = 14) had an undersized stem. Gentamicin concentrations were measured in drain fluid and serum at set intervals for 3 days postoperatively. In both groups, local gentamicin concentrations were similar. After a high initial burst above the minimal inhibitory concentration (thin: 57.2 mg/L (SD 34.4), thick: 54.9 mg/L (SD 19.9), p = 0.823) local gentamicin concentrations declined rapidly. In both groups, serum concentrations never exceeded toxic levels (maximum 1.08 mg/L). In hybrid total hip arthroplasty, Hi-Fatigue Gentamicin Bone Cement resulted in effective and safe gentamicin concentrations. Clinical trial protocol number: PMCI 12/02.

Kalkar defekti olan femur intertrokanterik kırıklarında diafizer çimento desteğinin femur üst uç yük dağılımına etkisinin sonlu element analizi ile tayini

This study aims to investigate biomechanically positive and negative aspects of arthroplasties in combination with diaphyseal cement support as an alternative to calcar supported prosthesis on the proximal femoral load distribution, using finite element analysis method in a virtual environment in intertrochanteric fractures with calcar femoral defect. Three femur models were created using the ANSYS method. These were named as a intertrochanteric fracture model without calcar defect, an intertrochanteric fracture model with thick cement mantle and calcar defect, and an intertrochanteric fracture model with thin cement mantle and calcar defect. In the finite element analysis setting, two regions were analyzed for load distributions. The first one was the whole femur, while the other one was the region starting from trochanter minor and extending distally to the 5 cm area. In the trochanteric fracture model without calcar defect, the stress value in the whole femur was found to be 22.9 MPa; whereas it was 29.2 MPa in the 5 cm long section starting at the trochanter minor. The stress values were 23.6-29.9 MPa in the intertrochanteric fracture model with thick cement mantle and 24.2-32.1 MPa in the intertrochanteric fracture model with thin cement mantle and calcar defect. The statistical analysis was performed using t-test and a p value of >0.005 was found in all. Our study results showed that forming a type of calcar to be used in a hemiarthroplasty surgery and shaping of this region with bone cement does not produce further stress on the cement/bone intersection in intertrochanteric fractures with defected calcar region.

Bone remodeling in the resurfaced femoral head: Effect of cement mantle thickness and interface characteristics

Metal-on-metal hip resurfacing prostheses were re-introduced during the last 10–15 years. These prostheses have the potential to better restore normal function with limited activity restriction, being an option for younger and more active patients. Resurfacing procedures have demonstrated high failure rates in national registers [1,2]. Multiple factors may affect early and long-term HR performance. The influence of femoral cement mantle thickness and different interface characteristics between the prosthesis components on the long-term performance of resurfacing prostheses is still unknown. In the present work, a model was used to predict bone remodeling with different mantle thicknesses and interface characteristics. A very thin cement mantle (0.25mm) increased bone resorption at the superior femoral head, while greater thickness (1 or 3mm) had a lesser effect. In all cases, bone apposition was predicted around the stem and at the stem tip. Bone formation and resorption were observed clinically in good agreement with the predictions calculated in simulations. Computed results showed that 1-mm cement mantle thickness combined with a bonded bone–cement interface and a debonded implant–cement interface was an appropriate configuration. Bone remodeling results and computed equivalent strains were correlated. In conclusion, we have been able to demonstrate the importance of choosing an adequate cement mantle thickness. Additionally, computational studies should consider realistic interface characteristics between the components in order to perform simulations closer to reality.

Effect of cementing technique and cement type on thermal necrosis in hip resurfacing arthroplasty—a numerical study

Femoral fractures within resurfacing implants have been associated with bone necrosis, possibly resulting from heat generated by cement polymerization. The amount of heat generated depends on cement mantle volume and type of cement. Using finite element analysis, the effect of cement type and volume on thermal necrosis was analyzed. Based on CT-data of earlier implantations, two different models were created: a thick mantle model, representing a low-viscosity "cement filling" technique, and a thin mantle model, representing a high viscosity "cement packing" technique. Six cement types were analyzed. The polymerization heat generation and its effect on bone necrosis were predicted. In the thin cement mantle models, no thermal necrosis was predicted. Thick cement mantle models produced thermal necrosis at the cement-bone interface depending on cement type. In the worst case, 6% of the bone at the cement-bone interface became necrotic, covering almost the entire cross-sectional area. The current findings suggest a potential thermal drawback of thick cement mantles, although it is unclear whether thermal bone necrosis significantly affects implant fixation or increases the fracture risk. Furthermore, our study showed distinct differences between the heat generated and resulting thermal damage caused by the various cement types.

Effect of undersizing on the long-term stability of the Exeter hip stem: A comparative in vitro study

Background Even for clinically successful hip stems such as the Exeter-V40 occasional failures are reported. It has been reported that sub-optimal pre-operative planning, leading to implant undersizing and/or thin cement mantle, can explain such failures. The scope of this study was to investigate whether stem undersizing and a thin cement mantle are sufficient to cause implant loosening. Methods A comparative in vitro study was designed to compare hip implants prepared with optimal and smaller than optimal stem size. Exeter-V40, a highly polished cemented hip stem, was used in both cases. Tests were carried out simulating 24 years of activity of active hip patients. A multifaceted approach was taken: inducible and permanent micromotions were recorded throughout the test; cement micro-cracks were quantified using dye penetrants and statistically analyzed. Findings The implants with an optimal stem size withstood the entire mechanical test, with low and stable inducible micromotions and permanent migrations during the test, and with moderate fatigue damage in the cement mantle after test completion. Conversely, the undersized specimens showed large and increasing micromotions, and failed after few loading cycles, because of macroscopic cracks in the proximal part of the cement mantle. While results for the optimal stem size are typical for stable hip stems, those for the undersize stem indicate a critical scenario. Interpretation These results confirm that even a clinically successful hip prosthesis such as the Exeter-V40 is prone to early loosening if a stem smaller than the optimal size is implanted.

The posterior approach reduces the risk of thin cement mantles with a straight femoral stem design

Background and purpose The properties of the cement mantle around a prosthesis are important. We investigated whether the surgical approach to the hip influences the quality and thickness of the cement mantle when using a straight femoral stem design.Methods In a consecutive multi-surgeon series, we reviewed the radiographs of 270 patients after cemented Exeter total hip arthroplasty. 135 stems were introduced using an antero-lateral (transgluteal) approach and 135 stems were introduced using a posterior approach. Anterior-posterior and lateral radiographs were reviewed and cement mantle thickness was measured in Gruen zones 1–14. We graded cement mantle quality according to the Barrack classification.Results Barrack grading did not reveal any difference in cement mantle quality between the two groups. AP and lateral radiographs showed no difference in stem alignment between the groups. The risk of a thin cement mantle (< 2 mm) was lower with a posterior approach (OR = 1.8, 95% CI: 1–3; p = 0.03). The greatest risk of a cement mantle thickness of < 2 mm occurred in Gruen zones 8–9 regardless of the surgical approach used.Interpretation With a straight femoral stem design, the posterior approach to the hip joint appears to give a lower risk of a thin cement mantle. Irrespective of the approach, there was a risk of thin cement mantles in Gruen zones 8 and 9, which highlights the importance of lateral radiographs in the postoperative radiographic assessment of total hip replacements.

Computational assessment of the effect of polyethylene wear rate, mantle thickness, and porosity on the mechanical failure of the acetabular cement mantle

Clinical studies have revealed that aseptic loosening is the dominant cause of failure in total hip arthroplasty, particularly for the acetabular component. For a cemented polyethylene cup, failure is generally accompanied by the formation of fibrous tissue at the cement-bone interface. A variety of reasons for the formation of this tissue have been suggested, including osteolysis and mechanical overload at the cement-bone interface. In this study, a computational cement damage accumulation method was used to investigate the effect of polyethylene cup penetration, cement mantle thickness, and cement porosity on the number of cycles required to achieve mechanical fatigue failure of the cement mantle. Cup penetration was found to increase cement mantle stresses, resulting in a reduction in cement mantle fatigue life of 9% to 11% for a high cup penetration rate. The effect of using a thin (2 mm) over a thick (4 mm) cement mantle also reduced cement mantle fatigue life between 9% and 11%, and greatly raised cancellous bone stresses. Cement porosity was found to have very little effect on cement mantle fatigue life. Failure modes and cement stresses involved suggest that only extreme combinations of a thin cement mantle and high cup penetration may lead to mechanical failure of the cement mantle, thereby allowing wear debris access to the cement-bone interface. A thin cement mantle may also lead to the mechanical overload of the cement-bone interface. In this manner, the authors suggest that the mechanical factors may contribute to the failure mode of cemented polyethylene cups.

Anatomic stem design reduces risk of thin cement mantles in primary hip replacement

To analyse the influence of femoral stem design in the lateral plane (anatomic vs. straight) on the cement mantle quality. In this consecutive multi-surgeon radiographic study we determined, Dorr grading, cement mantle quality (Barrack) and mantle thickness using Gruen zones 1–14 in 280 primary cemented total hip replacements, divided into two groups (140 anatomic Biomet Olympia, 140 straight Exeter Universal Series). Twenty-three per cent of the straight Exeter Universal stems had a cement mantle of <2 mm thickness in Gruen zone 8 and 25% in Gruen zone 9, compared to 0.7% of the anatomical Olympia stems in Gruen zone 8 and 1.4% in Gruen zone 9. The difference between the two groups was statistically significant (P < 0.001). In all other zones no significant differences were found. This radiological study confirms that femoral stems with an anatomical curve in the lateral plane carry a lower risk of thin cement mantles (especially in Gruen zones 8 and 9) than straight stems. Cement mantle analysis in one radiographic plane only is insufficient.

The condition of the Cement Mantle in Femoral Hip Prosthesis Implantations – a Post Mortem Retrieval Study

Despite numerous studies demonstrating the characteristics of the optimal cement mantle in joint replacement, the clinical state of the cement mantle is rarely assessed. A random sample of 214 cemented implanted femoral hip components was retrieved post mortem from Hamburg, Germany, and sectioned to investigate the quality of the cement mantle. The most common observation made in at least one measured region per retrieval was debonding (82% of stems), followed by a thin cement mantle (74%), stem-bone contact (48%), soft tissue at the stem interface (44%), no cement-bone interdigitation (30%), a gap at the stem interface (28%), voids in the cement (22%) and cracks and blood in the cement mantle (<10%). 21% of stems demonstrated complete debonding of the interface. However, distributions of all other defects were local, with less than 10% of stems demonstrating any imperfection in more than 21% of the regions assessed. No progressive damage was observed with implantation duration. The results suggest that current implantation technique may be adequate for proper implant function over the service life in the older patient population. However, for younger and more active patients, perfection of the cementation technique is crucial, particularly in modern implant systems such as resurfacing. The frequency of almost all defects could be further reduced by careful implantation technique, providing the increased service life necessary for the ever younger, more physically demanding, patient population.

The effects of femoral canal geometries, stem shapes, cement thickness, and stem materials on the choice of femoral implant in cemented total hip replacement

Cement failure is a main factor leading to localized bone lysis, and later to aseptic loosening in cemented total hip replacement. But the effects of the cement thickness, stem shapes and materials on the cement failure and the choice of femoral implant in different femoral canal shapes after total hip arthroplasty have rarely been investigated. Finite element models of proximal femurs including normal and stovepipe femoral canal shapes were used to predict the failure of cement mantles for different cement thicknesses, stem shapes and materials. The results showed that high failure probabilities and tensile stress occurred in the distal region of the cement mantle in the stovepipe canal model. A high flare stem, reducing the stress in the distal region of the cement mantle, was modeled by adopting a thick cement mantle (2 mm). In addition, extra high failure probabilities and tensile stress occurred in the cement mantle while adopting a thin cement mantle (0.5 mm). In the models with titanium alloy stems, the peak tensile stress and failure probabilities in the cement mantle presented similar results compared to CoCrMo alloys. We concluded that a high flare stem, either titanium or CoCrMo alloy, could decrease the rate of stem loosening for patients with stovepipe canals.

Increased long-term failure risk associated with excessively thin cement mantle in cemented hip arthroplasty: A comparative in vitro study

Increased long-term failure risk associated with excessively thin cement mantle in cemented hip arthroplasty: A comparative in vitro study

Thermal Effects of Cement Mantle Thickness for Hip Resurfacing

Hybrid hip resurfacing arthroplasty with uncemented acetabular and cemented femoral fixation is increasingly becoming popular as an alternative to total hip arthroplasty. There is concern about femoral neck fractures, and long-term survival has not yet been demonstrated. Thermal necrosis may be an important factor for neck fracture and will affect the viability of the femoral bone. This cadaveric study investigated the thermal effect of thick (1.5 mm, n = 3) and thin (0.5 mm, n = 3) cement mantles; 5 thermocouples were used to record temperature at the femoral bone/cement interface during hip resurfacing arthroplasty. The highest recorded temperatures were significantly higher when a thick cement mantle is used (45.4°C), compared to a thin cement mantle (32.7°C). To reduce the potential for thermal necrosis, the thin cement mantle technique is recommended.

Femoral Stem Tip Orientation and Surgical Approach in Total Hip Arthroplasty

A posterior entry point, a neutral tip position and neutral stem alignment are recommended to avoid a thin cement mantle and ensure an optimal outcome in total hip arthroplasty (THA). Our aim was to highlight any influence of surgical approach in obtaining an optimal stem orientation. We examined the post-operative, digitised radiographs of 100 (50 each group) polished, tapered Exeter THA, inserted via the antero-lateral or posterior approaches. Stem tip position was assessed in both coronal and sagittal planes and stem alignment was assessed in the coronal plane. There was a significant difference between the two approaches in the sagittal stem tip position only (p=0.01). Our results illustrate that a neutral stem tip position in THA is significantly more difficult to obtain with an antero-lateral approach, when compared to the posterior approach. A posterior approach to the hip avoids the cuff of glutei that can lever the proximal stem anteriorly causing an anterior entry point and a posterior stem tip position. We also illustrate how the anatomy of the proximal femur in the sagittal plane makes a neutral stem alignment difficult to achieve with either approach.

Increased long-term failure risk associated with excessively thin cement mantle in cemented hip arthroplasty: A comparative in vitro study

There is no consensus on possible detrimental effects of reduced thickness of the cement mantle surrounding hip stems. This work originated from the suspect that a successful design would yield inferior survival when implanted with a lower cement thickness. The scope was to assess with a reproducible in vitro experiment if a thinner cement mantle could cause a reduction of the long-term implant fatigue resistance. A comparative in vitro study was designed based on the same commercial stem (Centrament, Aesculap), implanted with the recommended (2-3mm) and reduced (1-2mm) cement thickness. Tests were carried out simulating 24 years of activity of active hip patients. A multifaceted approach was taken: inducible and permanent micromotions were recorded throughout the test; cement micro-cracks were quantified using dye-penetrants and statistically analyzed; crack surface and stem-cement fretting damage was investigate under Scanning Electron Microscopy. The same stem, when implanted with a thinner cement mantle, tended to migrate significantly more (up to 0.3mm), with a tendency to loosen over time (increasing migration rate over time). After cyclic testing the cement mantle of the thinner specimens showed significantly more and longer cracks than the standard implants, with loose cement chips and signs of stem-cement fretting. All these results confirmed that: (i) the stem under investigation had a good performance (in comparison with similar published work) when implanted with the recommended thickness; (ii) micromotion, cement cracking and fretting damage significantly increased when reduced cement mantle was used. Excessively thin cement mantle can result in critical conditions even for designs, which, in general, show low complications.

Femoral stem tip orientation and surgical approach in total hip arthroplasty

A posterior entry point, a neutral tip position and neutral stem alignment are recommended to avoid a thin cement mantle and ensure an optimal outcome in total hip arthroplasty (THA). Our aim was to highlight any influence of surgical approach in obtaining an optimal stem orientation. We examined the post-operative, digitised radiographs of 100 (50 each group) polished, tapered Exeter THA, inserted via the antero-lateral or posterior approaches. Stem tip position was assessed in both coronal and sagittal planes and stem alignment was assessed in the coronal plane. There was a significant difference between the two approaches in the sagittal stem tip position only (p=0.01). Our results illustrate that a neutral stem tip position in THA is significantly more difficult to obtain with an antero-lateral approach, when compared to the posterior approach. A posterior approach to the hip avoids the cuff of glutei that can lever the proximal stem anteriorly causing an anterior entry point and a posterior stem tip position. We also illustrate how the anatomy of the proximal femur in the sagittal plane makes a neutral stem alignment difficult to achieve with either approach.

Tight Fit Technique in Primary Hybrid Total Hip Arthroplasty for Patients with Hip Dysplasia

This article presents the midterm results of hybrid total hip arthroplasty for patients with hip dysplasia by use of a tight fit technique for the femoral component. We followed up 113 hips in 99 patients for a mean of 11 years. All final femoral rasps used in this study overrasped by 0.5 to 1.0 mm for stem insertion, resulting in relatively thin cement mantles. Both components of one hip were removed because of infection. The other 5 acetabular components were revised for osteolysis, recurrent dislocation, or dislodgement of the polyethylene liner. No femoral component was revised for aseptic loosening. We conclude that the tight fit technique using a canal-filling stem may produce good long-term results for patients with hip dysplasia.

Clinical investigation of MS-30 (polished tapered stem) fixed with thin cement mantle

Clinical investigation of MS-30 (polished tapered stem) fixed with thin cement mantle

Four-angle radiographic assessment of cement mantle thickness in cemented total hip arthroplasty

In this study, the cement mantle thickness of 57 hips undergoing primary cemented total hip arthroplasty (THA) were investigated with 4 angle radiographs. All surgeries were performed with a standardized posterolateral surgical approach. In addition to conventional anteroposterior and lateral radiographs, obturator oblique and iliac oblique radiographs were taken. In the evaluation of the cementing grade on the anteroposterior radiograph, the incidence of hips with thin cement mantles was 25%. In evaluating the cementing grade on the anteroposterior and lateral radiographs, we found an incidence of hips with thin cement mantles of 37%. From the evaluations with 4 angle radiographs, 10 hips were additionally assigned as being of a poor cementing grade (Mulroy’s grade C-2). Thin cement mantles were mainly seen on the iliac oblique radiographs.