This study investigates the thermal-stress characteristics of a bi-metallic Ti-6Al-4V-Nitinol butt joints manufactured via laser welding. Particularly, the thermal profile along the weld interface and the deformation profile of the finished welded workpiece. A decoupled transient thermomechanical simulation model was constructed to recreate the welding process. This decoupled thermomechanical simulation model consisted of two transient simulation models. A transient thermal simulation model and a transient structural simulation model, with the thermal history of the transient thermal model being fed into the transient structural model. Both the thermal and structural portions of the model utilized temperature-dependent thermal and structural properties of Ti-6Al-4V and Nitinol. The temperature profile of the transient thermal-stress model aligns with the experimental thermal profile within 5% error. The deformation profile also matches the experimental results within 5% error. This approach to modeling laser welding can stand as a guide to predict both thermal and deformation profiles generated during the laser welding process.