AbstractThe thermal flow curves of the nitrolysis for the synthesis of 3,7‐dinitro‐1,3,5,7‐tetraazabicyclo[3.3.1]nonane (DPT) from hexamine in the presence of different amounts of acetic anhydride were obtained using reaction calorimetry. The maximum heat release rates during the feeding process, the corresponding maximum adiabatic temperature rises, and the Maximum Temperature of the Synthesis Reaction (MTSR) were determined, respectively. The thermal stability of the reaction product DPT and the reaction mixture was analyzed, and data on their thermal decomposition characteristics were obtained. The thermal decomposition kinetic model was utilized to simulate the stability under adiabatic conditions. TD24 (The temperature corresponding to the time required to reach the maximum reaction rate under adiabatic conditions for 24 hours) of the reaction mixture was calculated as 69.65°C. According to the thermal hazard parameters of the reaction, the process's hazard level under various acetic anhydride addition conditions was determined to be level 5 using the cooling failure scenario method.