Laser therapy is a complex of hardware procedures that involve exposure of the skin to light energy and allows getting rid of a number of skin imperfections. Objective — to study the possibilities, effectiveness and expediency of using laser technologies to solve some dermatoesthetic problems in patients. Materials and methods. The results of the therapy using the Nordlys device, the principle of operation of which is based on the theory of selective photothermolysis, were analyzed and presented. The Dermatology Life Quality Index (DLQI) was used to determine the effectiveness of the treatment. Results and discussion. We observed 118 patients aged 18 to 65 years (42 men and 76 women) with different dermatoesthetic problems. The Nordlys narrow-spectrum IPL technologies were used to treat couperose, rosacea, acne and hyperpigmentation. As a result of the comprehensive treatment using laser therapy, the DLQI indicators statistically significantly improved in patients of all groups: in patients with couperose and rosacea — by 48.75 and 72.71 %, respectively, acne and post-acne — by 77.87 and 72.07 %, respectively, superficial and deep pigmentation — by 40.49 and 50.98 %, respectively (p < 0.001). Before treatment, only 30.51 % patients experienced a moderate impact of skin disease on the life quality, while 69.49 % patients noted a significant impact. However, after the combination treatment using laser therapy, only 11.86 % patients felt a significant impact of their skin disease on their life quality, while all the other 88.14 % patients noted a significant improvement in the life quality. Conclusions. Laser therapy in the comprehensive treatment of patients with dermatological and aesthetic problems makes it possible to reduce the clinical manifestations of dermatoses, eliminate some factors of their development, and contributes to a probable (p < 0.05) improvement in quality of life.