Purpose: Sub-Saharan Africa (SSA) is a region that is most affected by both conflict and climate change, with the Sahel, Southern Africa, and East Africa impacted severely. Research has shown climate change is a ‘threat multiplier’ while low state capability and high poverty are core conflict drivers. However, climate change gradually contributes to political, socioeconomic and environmental insecurity and fragility. This study examines perspectives of peace, security and health during climate change in SSA and explores strategic options for the region. Theoretical reference: This study is underpinned by the greenhouse effect, which is a theory of anthropogenic global warming (AGW) supported by the Intergovernmental Panel on Climate Change (IPCC). Methods: This study was grounded in the postmodernist philosophy, and data was obtained using desktop research methodology. This involved reviewing academic studies and grey literature. Results and conclusion: Conflict prevention measures should ensure that climate change adaptation strategies are effectively implemented because its consequences in the region are now visible. Climate change should not be framed merely as a threat to security but as a security issue, although its role as a threat multiplier must not be trivialised or denied. Some vector-borne diseases sensitive to climate change represent an express cause for health concern, calling for evidence-based solutions. Implications of the research: Climate change has a multiplier effect on conflict and health concerns, which are less understood. Originality/Value: Although climate change does not directly cause conflict and health challenges, this study adds to the policy debate and literature by focusing on the indirect effects of climate change on peace, security and health.