Aiming at the problem of error estimation of smart meters in distribution network, a method of error estimation of smart meters based on particle swarm optimization convolutional neural network is proposed. This method establishes an intelligent energy meter error estimation model through data collection, data prediction, and preprocessing. To address the convergence issue in training, the interlayer distribution of weights is adjusted to improve training quality. This method fully utilizes template calibration information to transform indicator detection under complex conditions into simple and effective isometric segmentation, transforming label recognition from complex text detection and recognition tasks to simple and efficient binary detection tasks, with better robustness. The effectiveness and high robustness of the proposed method have been demonstrated through experimental verification.