Tests Of Simple Main Effects Research Articles

Efficacy of acupuncture for a cough-related symptom cluster in patients with lung cancer: A randomized controlled trial

PurposeThis study was designed to evaluate the effect of acupuncture on cough, expectoration, and shortness of breath in lung cancer patients. MethodsBetween December 2021 and June 2022, a total of 130 lung cancer patients were recruited, and they were split into control and intervention groups at random. Routine nursing was provided to the control group, whereas routine nursing with acupuncture using LU7 (Lie Que), LU9 (Tai Yuan), BL13 (Fei Shu), and BL20 (Pi Shu) was administered to the intervention group for 7 days. The severity of cough, expectoration, and shortness of breath was assessed 1 day before and after the interventions using the lung cancer-specific module of the MDASI. A two-way ANOVA was performed for group comparisons. ResultsCompared with the control group, the symptoms of cough in the intervention group were significantly improved (F = 5.095, MD = −0.32, 95% CI, −0.59 to 0.04, P = 0.025), while expectoration (F = 0.626, MD = −0.11, 95% CI, −0.38 to 0.16, P = 0.430) and shortness of breath (F = 0.165, MD = −0.05, 95% CI, −0.27 to 0.18, P = 0.685) had no significant change. Cough also identified an obvious interaction effect (P = 0.014), and the post-intervention simple main effect test demonstrated a tangible difference between the two groups (MD = −0.66, 95% CI, −0.99 to 0.33, P < 0.001) post-intervention. ConclusionsAcupuncture using LU7, LU9, BL13, and BL20 can relieve the cough of lung cancer patients, but not relieve expectoration and shortness of breath.

Impairments of social interaction in a valproic acid model in mice.

A rodent autism spectrum disorder (ASD) model based on prenatal exposure to valproic acid (VPA) is widely recognized as a prominent model. Social behavior in rodent ASD models has primarily been evaluated through a three-chamber approach test. However, in this study, we focused on social attention in the VPA model of ASD. In male C57BL/6 J mice, attentional behaviors toward conspecifics were examined through reaching tasks around 9-11 weeks of age. On embryonic day 12.5, pregnant mice underwent a subcutaneous injection of 600 mg/kg VPA sodium salt dissolved in 0.9% saline solution (VPA group) or saline solution alone (Sal group) into their neck fat. Thirty-six mice-nine each in the VPA and saline groups, and 18 partners-underwent training in reaching behavior. Subsequently, we examined whether the VPA or Sal group demonstrated focused attention toward their partners during reaching tasks. A two-way analysis of variance (ANOVA) (condition [VPA/Sal] × situation [face-to-face (attention)/not paying attention (not attention)]) was conducted on the average success rate of the situation. Additionally, we measured the duration of sniffing behavior between pairs of mice in an open field twice in total at 4 and 8 weeks of age before reaching task. The pairs were constructed by pairing a VPA or Sal group mouse with its partner, with the objective of facilitating initial encounters between the mice. A one-way ANOVA was conducted on the average duration of sniffing behavior data from 4 weeks and a second one-way ANOVA on data from 8 weeks. The analysis revealed a significant interaction between condition and situation in the reaching task [F (1, 28) = 6.75, p = 0.015, ηp 2 = 0.19]. The simple main effect test exhibited that the "not paying attention" rate was significantly higher than that of the "face-to-face" in the VPA group (p < 0.01). The results revealed a not significant difference in the average duration of sniffing behavior at 4 weeks [F (3, 32) = 2.71, p = 0.06, n.s., ηp 2 = 0.20], but significant difference at 8 weeks [F (3, 32) = 4.12, p < 0.05, ηp 2 = 0.28]. Multiple comparisons using the Bonferroni method revealed significant differences in the sniffing duration at 8 weeks between from the partner toward the VPA mouse and from the partner toward the Sal mouse (p < 0.05). The VPA rodent model of ASD exhibited differences in social attention compared to the saline group. By focusing on social attention and exploring various ASD models, insights can be gained from the neural mechanisms underlying gaze abnormalities during social interaction in individuals with ASD.

Phase transformation and mechanical properties of heat-treated nickel-titanium rotary endodontic instruments at room and body temperatures

BackgroundThe aim of this study was to evaluate the phase composition, phase transformation temperatures, bending property, and cyclic fatigue resistance of different heat-treated nickel-titanium (NiTi) rotary instruments with the same tip diameter and taper at room (RT; 25 ± 1 °C) and body (BT; 37 ± 1 °C) temperatures.MethodsFive heat-treated NiTi rotary instruments, HyFlex EDM (EDM), HyFlex CM (CM), Vortex Blue (VB), RE file CT (RE) and JIZAI, and a non-heat-treated NiTi rotary instrument (Mtwo) with a size 40, 0.04 taper were investigated. Temperature-dependent phase transformation was examined with differential scanning calorimetry (DSC). The bending loads of the instruments at RT and BT were evaluated using a cantilever-bending test. Cyclic fatigue resistance at RT and BT was measured using a dynamic test, during which the instruments were rotated in combination with a 2-mm back-and-forth motion in an artificial curved canal, and the number of cycles to failure (NCF) was determined. The results were analyzed using two-way repeated measures analysis of variance, a simple main effect test, and the Bonferroni test (α = 0.05).ResultsDSC results indicated that EDM and Mtwo were primarily composed of martensite/R-phase and austenite, respectively, while the other heat-treated instruments were composed of a mix of martensite/R-phase and austenite at the tested temperatures. Regardless of the temperature setting, the bending loads of heat-treated instruments were significantly lower than those of Mtwo (p < 0.05). EDM showed the lowest bending loads and highest NCF at both temperatures (p < 0.05). CM, VB, and JIZAI showed significantly higher bending loads at BT than at RT (p < 0.05). The NCF of all the heat-treated instruments, except VB, was lower at BT than at RT (p < 0.05). At BT, the NCF of CM, VB, RE, and JIZAI were not significantly higher than that of Mtwo (p > 0.05).ConclusionsHeat-treated NiTi instruments exhibited lower bending loads and higher NCF values than Mtwo. However, this tendency was less pronounced at BT than at RT, especially in the NCF values of instruments with a mixture of martensite/R-phase and austenite phases at the tested temperatures.

The Interaction of Unmitigated Communion and Gender on Gender System Justification

This study examined the interaction between unmitigated communion (UC) and gender on gender system justification (GSJ). UC is a trait of putting others before oneself. GSJ is a tendency to maintain the status quo, even if it is unequal. Participants included 200 females and 200 males (Mage=20.5). Hierarchical multiple regression analysis was conducted including the interaction terms of UC and GSJ. Since the interaction was significant, a simple main effect test was conducted, a positive association for females, and a negative association for males. The results were interpreted regarding the fit in society for females and a lack of merit for males.

Micro-CT analysis of marginal and internal fit of milled and pressed polyetheretherketone single crowns

Statement of problemPolyetheretherketone (PEEK) has been increasingly used as a framework material in prosthetic dentistry. However, data on the marginal and internal fit of PEEK restorations fabricated by using either the computer-aided design and computer-aided manufacturing (CAD-CAM) or heat-pressing technique are sparse. PurposeThe aim of this in vitro study was to assess the marginal and internal fit of milled and pressed PEEK single crowns by using microcomputed tomography (μCT). Material and methodsA custom-made, single stainless-steel die was designed to replicate a maxillary first premolar prepared for a ceramic crown. PEEK copings (N=30) were fabricated and allocated to 3 groups (n=10) according to the fabrication technique: milled from a prefabricated PEEK blank, heat pressed from PEEK pellets, and heat pressed from PEEK granules. All copings were veneered with a composite resin material. The marginal fit was recorded at 4 predetermined points and the internal fit at 8 predetermined points on each crown by using μCT. Two-way ANOVA, pair-wise Tukey honestly significant difference (HSD), and simple main effect tests were used for statistical analysis of the data (α=.05). ResultsConcerning marginal fit, the milled crowns demonstrated the best marginal fit overall (44 ±3 μm), followed by those pressed from pellets (92 ±3 μm), and finally by those pressed from granules (137 ±7 μm) (P<.001). The interaction between the effects of the fabrication technique and the measurement point on the marginal fit was not statistically significant (P=.142). The milled crowns demonstrated the lowest mean gap values overall, followed by those pressed from pellets and those pressed from granules (P<.001). The interaction between the effects of the fabrication technique and the measurement point on the internal fit was statistically significant (P<.001). Except for the distal occlusal gap and mesial occlusal gap, all tested groups showed a statistically significant difference (P<.001). In addition, statistically significant differences were observed among all measurement points in different fabrication techniques (P<.001). ConclusionsThe marginal and internal fit of milled PEEK crowns was significantly better than pressed crowns. However, both CAD-CAM and heat-pressing techniques produced PEEK crowns with a clinically acceptable marginal and internal fit. The mean marginal gap of the PEEK crowns pressed from granules was above the range of clinically acceptable value.

Relation between Unmitigated Communion and Friendship Satisfaction: Gender as a Moderator

This study examined the relationship between unmitigated communion and friendship satisfaction, with gender as a moderator. The participants were 232 females and 132 males (mean age=19.6). Hierarchical multiple regression analysis was conducted with friendship satisfaction as the dependent variable. Gender and unmitigated communion were independent variables. Results showed that the interaction term between gender and unmitigated communion was significant. A simple main effect test indicated a negative association between unmitigated communion and friendship satisfaction only for females. Gender was shown to be a moderator, which was discussed in terms of self-disclosure.

Persistent Non-pharmacological Pain Management and Brain-Predicted Age Differences in Middle-Aged and Older Adults With Chronic Knee Pain.

Chronic pain has been associated with changes in pain-related brain structure and function, including advanced brain aging. Non-pharmacological pain management is central to effective pain management. However, it is currently unknown how use of non-pharmacological pain management is associated with pain-related brain changes. The objective of the current study was to examine the association between brain-predicted age difference and use of non-pharmacological pain management (NPM) in a sample of middle-aged and older adults with and without chronic knee pain across two time points. One-hundred and 12 adults (mean age = 57.9 ± 8.2 years) completed sociodemographic measures, clinical pain measures, structural T1-weighted brain magnetic resonance imaging, and self-reported non-pharmacological pain management. Using a validated approach, we estimated a brain-predicted age difference (brain-PAD) biomarker, calculated as brain-predicted age minus chronological age, and the change in brain-PAD across 2 years. Repeated measures analysis of covariance was conducted to determine associations of non-pharmacological pain management and brain-PAD, adjusting for age, sex, study site, and clinical pain. There was a significant time*pain/NPM interaction effect in brain-PAD (p < 0.05). Tests of simple main effects indicated that those persistently using NPM had a “younger” brain-PAD over time, suggesting a potential protective factor in persistent NPM use. Future studies are warranted to determine the influence of NPM in brain aging and pain-related neurological changes.

Dependence of Thermoformed Mouthguard Thickness on Model Height in Single-Layer and Laminated Mouthguards

The height of the working model affects the mouthguard thickness. The aim of this study was to clarify the difference in the effect of model height on the thickness between single- and double-layered mouthguards. Mouthguards were thermoformed using ethylene-vinyl-acetate sheets and a pressure molding machine. Working models were three hard gypsum models with the height of the anterior part trimmed to 25 mm (model A), 30 mm (model B), and 35 mm (model C). Three molding conditions were compared: a single-layered mouthguard using a 4.0-mm thick-sheet (S4); a double-layered mouthguard using a 3.0-mm-thick sheet on the first-layer and a 2.0-mm-thick sheet on the second-layer (L32); and a double-layered mouthguard using 3.0-mm-thick sheets on first- and second-layers (L33). Analysis was performed by two-way ANOVA and a simple main effect test for the differences in the mouthguard thickness depending on the model height and the molding condition. Under all molding conditions, the labial and buccal thicknesses tended to become thinner as the model height increased, and models B and C were thinner by about 6% - 7% and about 14% - 16% than model A, respectively. The cusp thickness was not affected by the model height in L32 and L33, but in S4, models B and C were thinner about 14% or more than model A. Significant differences were observed among molding conditions, and S4 P < 0.01). This study suggested that the degree of the decrease in mouthguard thickness due to the increase the model height was similar for the single- and double-layered mouthguards on the labial and buccal sides, and increasing the model height by 5 mm and 10 mm decreased the thickness by about 6% - 7% and about 14% - 16%, respectively. At the cusp, only the single-layered mouthguard was affected by the model height.

Effect of dynamic loading on fracture resistance of gradient zirconia fixed partial denture frameworks

Statement of problemThe new strength-gradient zirconia composed of 3-mol% yttria-stabilized tetragonal zirconia polycrystal (3Y-TZP) and 5-mol% yttria-stabilized tetragonal zirconia polycrystal (5Y-TZP) has been claimed to have superior mechanical properties. However, data on the fracture resistance of 3-unit gradient 5Y-TZP and 3Y-TZP fixed partial denture frameworks are lacking. PurposeThe purpose of this in vitro study was to evaluate the effect of dynamic loading on the fracture resistance of gradient zirconia fixed partial denture frameworks. Material and methodsTwo standardized stainless-steel master dies were designed to simulate a mandibular left second premolar and second molar prepared to receive zirconia frameworks. The frameworks were designed with a 0.6-mm uniform wall thickness. The mesiodistal width of the connectors was 3 ±0.02 mm, and the occlusogingival height was 3 ±0.02 mm. Forty zirconia frameworks were fabricated and divided into 2 groups according to the tested materials (n=20): 3Y-TZP and gradient 5Y-TZP and 3Y-TZP. The frameworks were cemented onto their corresponding dies with a conventional glass ionomer cement. Half of the cemented frameworks in each group underwent 600 000 cycles of dynamic loading in a mastication simulator (n=10). The other half was fractured without dynamic loading (n=10). Fracture resistance measurements (N) for each framework were recorded by using a universal testing machine at a crosshead speed of 1 mm/min. A fractured framework from each group was examined by using a scanning electron microscope (SEM) at ×100 magnification. The data obtained were statistically analyzed by using 2-way ANOVA, the pairwise Tukey honestly significant difference (HSD), and simple main effect tests to detect the difference between group mean values (α=.05). ResultsThe mean ±standard deviation of fracture load value before dynamic loading was 1919 ±193 N for the 3Y-TZP group and 908 ±99 N for the gradient 5Y-TZP and 3Y-TZP group. In addition, the mean fracture load value after dynamic loading was 1418 ±163 N for the 3Y-TZP group and 716 ±85 N for the gradient 5Y-TZP and 3Y-TZP group. The interaction between the effects of the zirconia material and dynamic loading on the fracture resistance was statistically significant (P=.002). The 3Y-TZP group had a statistically significant, higher fracture load mean value the gradient 5Y-TZP and 3Y-TZP group before and after dynamic loading (P<.001). ConclusionsThe fracture resistance of 3Y-TZP frameworks was significantly higher than that of gradient 5Y-TZP and 3Y-TZP frameworks before and after dynamic loading. Dynamic loading significantly reduced the fracture resistance of 3Y-TZP and gradient 5Y-TZP and 3Y-TZP frameworks.

Parental stereotypes and cognitive processes: evidence for a double standard in parenting roles when reading texts

ABSTRACT While the characteristics associated with fathers have taken on more maternal traits more recently, a similar shift has not been observed for maternal characteristics. The role of mother remains stereotyped, and those who do not adhere to this often face criticism. This study examines the impact of parental stereotypes on the cognitive processes associated with reading. A sample of 32 individuals read 24 experimental passages introducing a parent (mother or father) in a traditional or non-traditional role, and in a neutral or disambiguating context. Results show a significant interaction between the type of role and gender of the parent on reading times. Simple main effect tests revealed that for traditional roles, fixation durations were longer when the protagonist was a father than when the protagonist was a mother. There was no effect of role type for fathers, yet for mothers, fixation durations were longer when they were depicted in non-traditional roles than when they were depicted in traditional roles. This disruption of information processing of schema incongruent content suggests that mothers’ parenting stereotypes remain anchored in society and are more rigid than those of fathers, supporting the idea of a double standard in parenting roles.

Differences of expected intervention effects between participant-led and facilitator-led preventive care services in Japan.

ObjectiveTo examine the effect of different management methods on the effectiveness of care preventive programmes for community-dwelling older adults.MethodsThis study comprised two facilitator-led (FL) and one participant-led (PL) preventive care classes in Japan. All participants received the intervention for approximately 12 weeks. Functional assessments, occupational dysfunctions, and subjective health were measured before and after the interventions. A two-way mixed design analysis of covariance (ANCOVA) was adopted to examine the effect of the interventions, adjusted for previous experiences with preventive care services. The level of significance was set at P < 0.05.ResultsFourteen participants in the PL group (76.64 ± 6.48 years, 92.9% women) and 29 participants in the FL group (76.55 ± 5.75 years, 75.9% women) were included in the statistical analysis. ANCOVA showed significant group × time interaction effects in the Five Times Sit-to-Stand Test (FTSST), the Timed Up & Go (TUG), occupational deprivation of the Classification and Assessment of Occupational Dysfunction Scale, and self-rated health. Simple main effect tests showed that the TUG decreased significantly in the PL group, while occupational deprivation and self-rated health scores improved significantly. In contrast, FTSST scores significantly improved in the FL group.ConclusionPL-type management may be more appropriate for preventing social isolation and withdrawal, while FL-type management may be more appropriate for preventing physical frailty. Selecting not only adequate programmes but also an appropriate management type that matches the service purpose can help provide more effective care preventive services.

Comparison of Torque, Screw-in Force, and Shaping Ability of Glide Path Instruments in Continuous Rotation and Optimum Glide Path Motion

IntroductionThis study aimed to analyze torque/force generation and transportation in double-curved canals instrumented with 3 types of glide path files using optimum glide path (OGP) motion in comparison with continuous rotation. MethodsSixty simulated double-curved canals were prepared with #10/0.05 or #15/0.03 HyFlex EDM Glidepath files (Coltene/Whaledent, Altstätten, Switzerland) or a #13/0.04 prototype MANI Glidepath file (Tochigi, Japan) using OGP motion or continuous rotation (n = 10 each). Canals were sequentially prepared to 20 mm and 22 mm (full working length) using automated root canal instrumentation and a torque/force analyzing device. Transportation was calculated at 1–9 mm from the apex. Data were compared using 2-way analysis of variance followed by a post hoc simple main effect test with Bonferroni correction and a Kruskal-Wallis test (α = 5%). ResultsAll #10/0.05 instruments fractured. In the 22-mm preparation, the OGP motion resulted in lower clockwise torque and screw-in force than did continuous rotation (P < .05). In the 20-mm preparation, #15/0.03 instruments recorded a lower screw-in force for OGP motion than for continuous rotation (P < .05). Comparing the 2 preparation phases, OGP motion generated no significant differences; however, continuous rotation developed higher clockwise torque and screw-in force in the 22-mm preparation than in the 20-mm preparation (P < .05). There was no significant difference among the tested groups for transportation values. ConclusionsCompared with continuous rotation, OGP motion generated less screw-in force, lower clockwise torque, and similar transportation. The #15/0.03 HyFlex EDM instrument and the #13/0.04 prototype MANI instrument performed similarly well.

Habitat-specific effects of interstitial space between stream substrate particles on the colonization of aquatic organisms

We examined the effects of interstitial space between stream substrate particles on the colonization of aquatic organisms using three types of substrates (gravel, a cobble, and a cobble on gravel) in a riffle and pool of a temperate stream. Significantly greater abundance, wet weight, diversity (H′), taxonomic richness, and evenness of aquatic organisms were found in the riffle than in the pool, and the interstitial space substrate (i.e., a cobble on gravel) had significantly greater abundance, wet weight, and taxonomic richness of aquatic organisms than did the cobble substrate. Of the 13 families observed in the experiments, larval net-spinning caddisfly (Hydropsychidae) dominated the riffle in terms of the abundance and wet weight; chironomid larvae dominated both the riffle and the pool in terms of abundance. Simple main effect tests indicated significant effects of substrate on the abundance and wet weight of larval caddisfly in the riffle, and post hoc tests on substrate in each habitat indicated that the abundance and wet weight of larval caddisfly on interstitial space substrate were significantly greater than those on cobble substrate in the riffle. Our results suggest the importance of interstitial space between stream substrates in riffles to ensure higher colonization rates of aquatic organisms such as larval net-spinning caddisflies characterized as filter feeders.

Retention of zirconia copings over smooth and airborne-particle-abraded titanium bases with different resin cements

Statement of problemHow cement type and the surface treatment of a titanium base affect the retention of zirconia copings on titanium bases is unclear. PurposeThe purpose of this in vitro study was to evaluate the dislodging forces of zirconium oxide copings cemented on implant-supported titanium bases with different luting agents and to examine the influence of airborne-particle abrasion on titanium surfaces. Material and methodsThirty implant laboratory analogs (BioHorizons) were fixed in metal blocks, and 30 prosthetic titanium bases (BioHorizons) were tightened with 35 Ncm of torque. Zirconium oxide copings with a luting-gap size of 30 μm were produced by using the Lava (3M ESPE) technology. The specimens were bonded to the titanium bases with 3 different resin cements (G-CEM LinkAce, RelyX U200, and Ceka Site). The specimens were kept in artificial saliva at 37°C for 24 hours and then subjected to a dynamic loading of 5000 cycles with a mastication simulator (SD Mechatronic) with thermocycling between 5°C and 55°C. The tensile force was measured by using a universal testing machine (Zwick/Roell) at a crosshead speed of 5 mm/min. After the measurement, the cement was cleaned from the titanium bases and zirconia copings. The titanium bases were airborne-particle abraded with 50-μm aluminum oxide (Al2O3) particles, and the bonding process was repeated. The statistical analysis included descriptive analysis, 2-way ANOVA, the Tukey post hoc, and simple main effect tests (α=.05). ResultsBond strengths were significantly different according to the cement type used and before and after airborne-particle abrasion (P<.05). The cement retentiveness before airborne-particle abrasion was as follows: G-CEM LinkAce (1338 ±69 N)>RelyX U200 (665 ±36 N)>Ceka Site (469 ±22 N). The differences among all the cement types before airborne-particle abrasion were statistically significant (P<.05). After airborne-particle abrasion, retention decreased in all the groups, and the ranking of the cements' retentiveness remained the same: G-CEM LinkAce (662 ±65 N)>RelyX U200 (352 ±21 N)>Ceka Site (122 ±17 N). After airborne-particle abrasion, the differences among all the cements remained statistically significant (P<.05). The comparison within the groups before and after airborne-particle abrasion revealed that abrading the titanium bases with 50-μm Al2O3 decreased the bond strength for all the tested cements. ConclusionsThe cement type had a significant influence on the retention of the zirconia copings, and abrading the titanium bases with 50-μm Al2O3 significantly decreased the dislodging force of the coping from the titanium base.

The Effectiveness of Training Programs on the Fidelity of Neuropsychological Tests.

There will probably be an exponential increase in the number of seniors suffering from dementia, as aging is the greatest risk factor for this disease. Therefore, neuropsychological tests to assessing dementia are likely to play an increasingly important role for medical services in Japan. This study developed and evaluated the usefulness of a training program on neuropsychological tests aimed at promoting the understanding of testers with regard to the cognitive functions and communication required in the neuropsychological testing process. The subjects of this study comprised 20 individuals engaged in administrating neuropsychological tests at the Japan-Multidomain Intervention Trial for Prevention of Dementia in Older Adults with Diabetes. A four-hour training session was held. The first part of the training program focused on "cognitive functions and communication;" the second addressed "neuropsychological tests." As the main evaluation criteria, a fidelity checklist was created with 14 items designed to measure success or failure with regard to important and easily mistakable aspects of implementing each neuropsychological test. They were conducted three times: before, immediately after, and six months after the training. The main effect of time was significant for the "fidelity" score. The effect size was large at η2 = 0.69. A simple main effect test using the Bonferroni method revealed significant differences between the pre-training and post-training values and between the pre-training and six-month point values. However, no significant differences were found in self-efficacy scores before, immediately after, and six months after the training. This outcome indicates that the fidelity of the subjects to neuropsychological tests increased as a result of the training program, and that this improvement was maintained through the six-month period following the program. Moreover, the large effect size suggests that the training program may be effective in facilitating the mastery of neuropsychological tests in testers.

Immediate effects of thoracic spine self-mobilization in patients with mechanical neck pain: A randomized controlled trial

ObjectivesTo investigate the immediate effects of thoracic spine self-mobilization in patients with mechanical neck pain. Study designRandomized, controlled trial. BackgroundThoracic spine self-mobilization is performed after thoracic spine thrust manipulation to augment and maintain its effects. To the best of our knowledge, no study has investigated the effects of thoracic spine self-mobilization alone in individuals with mechanical neck pain. The purpose of this randomized, controlled trial was to evaluate the immediate effects of thoracic spine self-mobilization alone without any other intervention on disability, pain, and cervical range of motion in patients with mechanical neck pain. MethodsFifty-two patients (39 females and 13 males) with mechanical neck pain were randomly allocated to either a thoracic spine self-mobilization group that was performing a thoracic spine active flexion and extension activity using two tennis balls fixed by athletic tape or a placebo thoracic spine self-mobilization group. Outcome measures were collected at pre-intervention and immediately after intervention, including the Neck Disability Index, visual analogue scale, and active cervical range of motion (ROM). The immediate effect of the intervention was analyzed using two-way repeated measures analysis of variance (ANOVA). If interactions were found, a simple main effect test was performed to compare the pre-post intra-group results. ResultsThe results of two-way repeated measures ANOVA indicated that the main effect of time was significant (p < 0.05) for all measurement outcomes. The main effect of group was not significant for all measurement outcomes (p > 0.05). The group × time interactions for cervical flexion active ROM (p = 0.005) and cervical extension active ROM (p = 0.036) were significant. The tests of simple main effect in cervical flexion active ROM (p < 0.0001) and cervical extension active ROM (p < 0.0001) showed a significant difference before and after intervention in the thoracic spine self-mobilization group. ConclusionPatients with mechanical neck pain who carried out thoracic spine self-mobilization showed increases in active cervical flexion and extension ROM.

Effectiveness of Aromatherapy Treatment in Alleviating Fatigue and Promoting Relaxation of Mothers during the Early Postpartum Period

Background: This study aimed to determine the effectiveness of aroma hand treatment in alleviating fatigue and promoting relaxation of mothers in their early postpartum period. Methods: This is a quasi-experimental study with a two-group pretest-post-test design which used purposive sampling and non-random assignment of 242 consenting Japanese early postpartum mothers who were patients from a hospital maternity unit in Tokyo, Japan. The intervention involved a 20-minute aroma hand treatment using an effleurage method. The participants selected from 5 essential oils: pure lavender, ylang-ylang, citron, rosewood, and sweet orange. Relaxation promotion and fatigue alleviation as the main outcomes were measured using self-administered valid and reliable questionnaires. Statistical analysis was performed using the two-sample t-test, two-way factorial ANOVA, and simple main effect test. SPSS ver. 23.0 (SPSS, Chicago, IL, USA) was used for data analysis at a 5% significance level. Results: Of 242 participants (intervention group, n = 122; comparison group, n = 120), 229 participants (intervention group, n = 115; comparison group, n = 114) were analyzed per protocol. The intervention group showed a significant improvement in relaxation (t = 6.43, p < 0.001). A significant difference in the simple main effect test of relaxation (F = 37.58, p < 0.001) was found. However, there was no significant reduction in fatigue. The majority (88.4%) of the participants indicated high satisfaction with the aroma hand treatment, and 90.5% evaluated the length of intervention time as appropriate. Conclusions: The aroma hand treatment effectively promoted relaxation of early postpartum mothers, but was less effective in alleviating their fatigue. Based on their high satisfaction rate, aroma hand treatment using essential oils may be considered effective in promoting relaxation of early postpartum mothers.

Personalized drinking feedback intervention for veterans of the wars in Iraq and Afghanistan: a randomized controlled trial.

Research has shown that U.S. military veterans are at risk relative to the general adult population for excessive alcohol consumption, and veterans of the wars in Afghanistan and Iraq (Operation Enduring Freedom [OEF], Operation Iraqi Freedom [OIF], and Operation New Dawn [OND]) particularly so. The purpose of this study was to examine the efficacy of a brief personalized drinking feedback intervention tailored for veterans. All veterans who presented to the OEF/OIF/OND Seamless Transition Clinic at the Harry S. Truman Memorial Veterans' Hospital (Columbia, MO) were eligible to participate. Participants were 325 veterans (93% male; 82% White, 75% Army, M(age) = 32.20 years) who were randomly assigned to one of two conditions: personalized drinking feedback (PDF) or educational information (EDU). Those in the PDF condition received personalized information about their alcohol use, including social norms comparisons, risks associated with reported drinking levels, and a summary of their alcohol-related problems. Follow-up assessments were completed at 1 and 6 months after intervention (response rates = 93% and 86%, respectively). Results indicated a significant (p < .05) Omnibus Group × Time effect for estimated peak blood alcohol concentration, although tests of simple main effects did not indicate between-group differences at the individual follow-up points. Among baseline abstainers, those in the PDF condition were more likely than those in the EDU condition to remain an abstainer at 6-month follow-up (p < .05). These findings provide preliminary support for the efficacy of a brief, inexpensive alcohol prevention/intervention for young adult military veterans.

Impact of a nursing education program about caring for patients in Japan with malignant pleural mesothelioma on nurses' knowledge, difficulties and attitude: A randomized control trial

In Japan nursing care lags behind the growing population of patients with malignant pleural mesothelioma. This study evaluated an educational program for nurses about caring for patients with malignant pleural mesothelioma in Japan. In this randomized controlled study relative to care for malignant pleural mesothelioma, Knowledge, Difficulties and Attitude were measured at baseline, at post-test and at follow-up one month later. The two-day program with a half-day follow-up program included lectures, group work, role-playing and group discussion. 188 participants were randomly assigned to the intervention group (program, n=96) and control group (n=92; self-study by a similar content handbook). At baseline the groups showed no statistical differences in Knowledge (p=0.921), Difficulty (p=0.458) and Attitude (p=0.922). Completing the study were 177 participants yielding 88 in the intervention group and 89 in the control group. Human rights and privacy of participants were protected. The Knowledge score was significantly higher in the intervention post-test (t=14.03, p=0.000) and follow-up test (t=8.98, p=0.000). Difficulty score was significantly lower in the intervention at post-test (t=-3.41, p=0.001) and follow-up test (t=-3.70, p=0.000). The Attitude score was significantly higher in the intervention post-test (t=7.11, p=0.000) and follow-up test (t=4.54, p=0.000). The two-way analysis of variance with repeated measures on time showed an interaction between time and group; the subsequent simple main effect test found significant differences (p=0.000-0.001) between groups for after-program and at follow-up and a significant difference (p=0.000) in time only within the intervention group. The educational program was effective in improving the nurses' knowledge and attitude toward malignant pleural mesothelioma care and decreasing the difficulty in MPM care, therefore this program has potential for nurses' in-service education throughout Japan.

The Relationship between Gender and Academic Success Online

Distance learning may pose challenges to students in terms of satisfaction and academic success. This study examined the relationship between the final grade received in a distance learning course and the student characteristic of gender. Examined were differences in online course achievement between male and female students through the lens of identity theory. The sample included 959 education majors at a regional university. Simple main effect tests were conducted after assumption tests for the planned analysis of covariance were not met. Findings indicated that for students with lower overall GPAs, there were differences in online course achievement between male and female education majors. For students with mid-level and higher overall GPAs, no differences existed.