Testin Research Articles

A METHOD FOR THE DETECTION AND QUANTIFICATION OF IMPAIRED SODIUM EXCRETION. RESULTS OF AN ORAL SODIUM TOLERANCE TEST IN NORMAL SUBJECTS AND IN PATIENTS WITH HEART DISEASE.

An oral sodium tolerance test was devised to detect and quantify impaired Na excretion in patients with heart failure. Following a 4-day period during which daily Na intake was limited to 10 mEq., 80 mEq. of Na were administered daily for 4 days and 150 mEq. for another 4 days. The total urinary Na excretion during the 8-day test period was determined. Thirteen normal subjects excreted between 550 and 734 mEq. of Na. Of 41 patients with heart disease, 31 excreted subnormal amounts of Na, between 10 and 550 mEq. and only 10 excreted normal quantities. An alternate plan, in which 320 mEq. of Na was administered in 8 days, was also utilized in patients in whom the standard 920-mEq. Na load was considered inadvisable. There was no correlation between the impairment of Na excretion, as estimated by the Na tolerance test, and the etiology of the heart disease, the glomerular filtration rate, or any hemodynamic variable. Patients with marked functional disability excreted less Na than those with few symptoms, and the patients with the most severe impairment of Na excretion all had a history of edema. Striking improvement in Na tolerance followed corrective cardiac operations. The Na tolerance test was found of particular usefulness in the evaluation of patients in whom clinical examination and hemodynamic studies gave no conclusive evidence as to the presence or absence of congestive heart failure.

AN ORAL TYROSINE TOLERANCE TEST IN THYROTOXICOSIS AND MYXEDEMA.

IN patients with thyrotoxicosis the concentration of tyrosine in plasma has been shown to increase1 , 2 whereas concentrations of other amino acids except glutamic acid have been normal.3 When loads of tyrosine were fed to hyperthyroid patients, plasma levels of tyrosine measured hourly for six hours were elevated several times above levels found in euthyroid patients.3 In similar assays of oral tyrosine tolerance in hypothyroid subjects plasma levels after a tyrosine load were decreased below levels found in euthyroid subjects.The present investigation was intended to determine whether abnormal responses to orally administered loads of tyrosine are restricted to patients with . . .

THE PROVERBS TEST IN THE APPRAISAL OF CEREBRAL DISEASE.

THE PROVERBS TEST IN THE APPRAISAL OF CEREBRAL DISEASE.

THE GUTHRIE TEST IN MONITORING THE DIET IN PKU: AN APPRAISAL OF ITS APPLICABILITY.

THE GUTHRIE TEST IN MONITORING THE DIET IN PKU: AN APPRAISAL OF ITS APPLICABILITY.

ORGANIC INTEGRITY TEST (OIT) IN CHILDREN.

Introduction THE ORGANIC Integrity Test (OIT) was first published in theArchives of General Psychiatry(3:43-52 (July) 1960) by Tien. 10 This test measures form perception as an indication of organicity as unrelated to Astrom confirmed the reliability and the validity of the OIT in Sweden (1963), 1 and Engelsmann confirmed it in Czechoslovakia. Astrom stated that Tien has, therefore, to great extent succeeded with that which many other test constructors before him have completely or partially failed to; that is, to produce an organic test which is relatively unrelated to intelligence. There is no reasonable doubt that the OIT measures organicity in adults. Astrom has compared to advantage the OIT with Benton's Visual Retention Test, 2 Koh's Blocks, and the performance tests of Wechsler for organicity. In adults, the OIT can show organicity which a clinical examination frequently fails to demonstrate, even

THE DIRECT ANTIGLOBULIN (COOMBS) TEST IN MEGALOBLASTIC ANAEMIA.

Folic acid deficiency with the picture of a megaloblastic bone marrow may develop in haemolytic anaemia, and, on the other hand, both vitamin B(12) and folic acid deficiency may produce signs of haemolysis. As the correct interpretation of a positive antiglobulin reaction associated with megaloblastic erythropoiesis is particularly important, the effect of deficiency of vitamin B(12) and folic acid on the results of the test was investigated in 32 patients with vitamin B(12) or folic acid deficiency and a positive antiglobulin reaction was obtained in ten. There was no correlation between the result of the test and the degree of anaemia, and there was no significant difference between the incidence of positive results associated with deficiency of vitamin B(12) or folic acid. In determining the significance of a positive result, the time interval before agglutination occurs is sometimes of greater value than the strength of the reaction or the result of the gamma globulin neutralization test.

COAGULATION TESTS IN ANTICOAGULANT THERAPY.

Medical Journal of AustraliaVolume 1, Issue 5 p. 150-154 Original Article COAGULATION TESTS IN ANTICOAGULANT THERAPY† David W. Davies, David W. Davies Senior Biochemist Commonwealth Health Laboratory CanberraSearch for more papers by this author David W. Davies, David W. Davies Senior Biochemist Commonwealth Health Laboratory CanberraSearch for more papers by this author First published: 01 January 1965 https://doi.org/10.5694/j.1326-5377.1965.tb71490.xCitations: 2 †A preliminary report on the findings detailed here was presented at the meeting of the Canberra Medical Society on June 27, 1963. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume1, Issue5January 1965Pages 150-154 RelatedInformation

ABNORMAL LIVER FUNCTION TEST IN PATIENTS WITH RHEUMATIC DISEASE WITH SPECIAL REFERENCE TO ELEVATED ALKALINE PHOSPHATASE.

(1) Twenty-seven cases of fever and heart disease were examined for liver status.(2) In 50%, Al-P was elevated. Other liver function tests were ab-normal with lesser degree.(3) No correlation between elevated Al-P and ZTT, CCF, ESR, ASL-O titer, SGOT, SGPT, ECG findings and clinical course.(4) Elevated Al-P activity tended to develop among patients with murmur at aortic valve.(5) These abnormalities seemed to be temporary and reversible.(6) No specific histological findings enough to be called rheumatic hepatitis were noted in histological examinations.(7) Possible causative factors for elevated Al-P in diseases were discussed.

RESULTS OF RESPIRATORY-FUNCTION TESTS IN MINERS

RESULTS OF RESPIRATORY-FUNCTION TESTS IN MINERS

METHOPYRAPONE TESTS IN HYPOTHALAMIC-PITUITARY DISEASE.

This study was designed to investigate the efficacy of the methopyrapone test in disclosing possible abnormalities in ACTH release in patients with central nervous system or pituitary disease who exhibited little or no endocrine impairment. Methopyrapone tests were carried out in 10 patients with primarily hypothalamic disease, and in 14 patients with sellar tumors presenting with primarily visual symptoms. Positive (normal) responses were obtained in 8 of 10 patients with hypothalamic disease and in 10 of 14 patients with pituitary disease. The findings in the patients with hypothalamic disease are in general agreement with other reported series. In contrast, the proportion of positive responses in the pituitary cases is higher than that in previously reported studies. This difference may reflect the absence of prior therapy (surgery or irradiation) to the pituitary area, and /or the lower incidence of endocrinopathy in our patients. In view of these findings, the value of the methopyrapone test in asses...

THE HISTOCHEMICAL DEMONSTRATION OF ZINC IN BLOOD GRANULOCYTES--THE NEW TEST IN DIAGNOSIS OF NEOPLASTIC DISEASES.

CancerVolume 17, Issue 11 p. 1381-1384 ArticleFree Access The histochemical demonstration of zinc in blood granulocytes—the new test in diagnosis of neoplastic diseases Dr. Stanislaw Szmigielski M.D., Corresponding Author Dr. Stanislaw Szmigielski M.D. Hematological Clinic, Institute of Hematology, Warsaw, Poland11/3 Pulawska St., Warsaw 12, Poland===Search for more papers by this authorJoanna Litwin M.D., Joanna Litwin M.D. Hematological Clinic, Institute of Hematology, Warsaw, PolandSearch for more papers by this author Dr. Stanislaw Szmigielski M.D., Corresponding Author Dr. Stanislaw Szmigielski M.D. Hematological Clinic, Institute of Hematology, Warsaw, Poland11/3 Pulawska St., Warsaw 12, Poland===Search for more papers by this authorJoanna Litwin M.D., Joanna Litwin M.D. Hematological Clinic, Institute of Hematology, Warsaw, PolandSearch for more papers by this author First published: November 1964 https://doi.org/10.1002/1097-0142(196411)17:11<1381::AID-CNCR2820171103>3.0.CO;2-PCitations: 23AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume17, Issue11November 1964Pages 1381-1384 ReferencesRelatedInformation

PREDISPOSITION TO DIABETES AS EVALUATED BY THE CORTISONE-GLUCOSE TOLERANCE TEST IN CHILDREN; A PRELIMINARY STUDY.

Cortisone-glucose tolerance tests with progressively increasing doses of the steroid were performed in healthy children born to diabetic parents belonging to different mating types. The results suggest that predisposition to diabetes can be detected in younger offspring by using a critical dose of cortisone.

DRUG‐SENSITIVITY TESTS IN GENERAL PRACTICE

Medical Journal of AustraliaVolume 2, Issue 22 p. 897-897 Correspondence DRUG-SENSITIVITY TESTS IN GENERAL PRACTICE First published: 01 November 1964 https://doi.org/10.5694/j.1326-5377.1964.tb109818.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume2, Issue22November 1964Pages 897-897 RelatedInformation

BLOOD GROUPING TESTS IN DISPUTED PARENTAGE QUALIFICATIONS OF EXPERTS. II. AN ERROR INVOLVING THE RARE RH-HR BLOOD TYPES RHZRHI AND RHZRH.

SUMMARYAn unusual case is described in which a man was accused of the paternity of a child, and an expert reported him to be type RhzRh1, the mother as type Rh1rh and the child as type Rh2rh, thus excluding paternity. In repeat blood tests, the author confirmed the typing results on the putative father and the mother, but showed the child to be type Rhzrh instead of type Rh2rh, so that paternity was not excluded. Instead, the presence in both putative father and child of the rare gene RZ (or ry) could be considered circumstantial evidence that the accused man actually was the father. It is pointed out that the error could easily have been due to the mistaken use of anti-rhi serum in place of anti-rh′ serum. Such an error would be more apt to occur with a worker using the fallacious C-D-E notations, because the tacit assumption implicit in those notations that each agglutinogen has but a single corresponding antibody (and blood factor) would render unthinkable the concept of more than one kind of anti-rh′ (anti-C) reagent.

PAPANICOLAOU TESTS IN HOBART

Medical Journal of AustraliaVolume 2, Issue 15 p. 609-609 Correspondence PAPANICOLAOU TESTS IN HOBART First published: 01 October 1964 https://doi.org/10.5694/j.1326-5377.1964.tb119848.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume2, Issue15October 1964Pages 609-609 RelatedInformation

QUALITY CONTROL AND NONDESTRUCTIVE TESTING IN THE CONSTRUCTION OF MARINE NUCLEAR POWER PLANT

Naval Engineers JournalVolume 76, Issue 5 p. 753-769 QUALITY CONTROL AND NONDESTRUCTIVE TESTING IN THE CONSTRUCTION OF MARINE NUCLEAR POWER PLANT THE SHIPBUILDER AND MARINE ENGINEER, THE SHIPBUILDER AND MARINE ENGINEERSearch for more papers by this author THE SHIPBUILDER AND MARINE ENGINEER, THE SHIPBUILDER AND MARINE ENGINEERSearch for more papers by this author First published: October 1964 https://doi.org/10.1111/j.1559-3584.1964.tb04069.xAboutPDF ToolsExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Volume76, Issue5October 1964Pages 753-769 RelatedInformation

THE EFFECT OF TREATMENT ON THE INTRAVENOUS GLUCOSE TOLERANCE TEST IN MALIGNANT DISEASE.

THE EFFECT OF TREATMENT ON THE INTRAVENOUS GLUCOSE TOLERANCE TEST IN MALIGNANT DISEASE.

THE INDIRECT BASOPHIL DEGRANULATION TEST IN ALLERGIC RHINITIS.

AllergyVolume 19, Issue 4 p. 300-304 THE INDIRECT BASOPHIL DEGRANULATION TEST IN ALLERGIC RHINITIS LENNART JUHLIN, LENNART JUHLIN Department of Dermatology (Head: Nils Thyresson, M.D.). University Hospital, Upsala, Sweden.Search for more papers by this authorLARS WIBELL, LARS WIBELL Department of Dermatology (Head: Nils Thyresson, M.D.). University Hospital, Upsala, Sweden.Search for more papers by this author LENNART JUHLIN, LENNART JUHLIN Department of Dermatology (Head: Nils Thyresson, M.D.). University Hospital, Upsala, Sweden.Search for more papers by this authorLARS WIBELL, LARS WIBELL Department of Dermatology (Head: Nils Thyresson, M.D.). University Hospital, Upsala, Sweden.Search for more papers by this author First published: August 1964 https://doi.org/10.1111/j.1398-9995.1964.tb03250.xCitations: 5AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume19, Issue4August 1964Pages 300-304 RelatedInformation

DAZZLING TEST IN DISEASES OF THE RETINA

Acta OphthalmologicaVolume 42, Issue 2 p. 517-517 DAZZLING TEST IN DISEASES OF THE RETINA H. Forsius, H. ForsiusSearch for more papers by this authorU. Krause, U. KrauseSearch for more papers by this authorA. W. Eriksson, A. W. ErikssonSearch for more papers by this author H. Forsius, H. ForsiusSearch for more papers by this authorU. Krause, U. KrauseSearch for more papers by this authorA. W. Eriksson, A. W. ErikssonSearch for more papers by this author First published: June 1964 https://doi.org/10.1111/j.1755-3768.1964.tb03647.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume42, Issue2June 1964Pages 517-517 RelatedInformation

REPORT OF THE USE OF DRUG SENSITIVITY TESTS IN GENERAL PRACTICE

Medical Journal of AustraliaVolume 1, Issue 19 p. 736-737 Correspondence REPORT OF THE USE OF DRUG SENSITIVITY TESTS IN GENERAL PRACTICE First published: 01 May 1964 https://doi.org/10.5694/j.1326-5377.1964.tb114224.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume1, Issue19May 1964Pages 736-737 RelatedInformation