Testicular Epidermoid Cysts Research Articles

Clinical analysis of 23 cases of epidermoid cyst of testis in children.

This study aims to examine the clinical characteristics and surgical management of pediatric testicular epidermoid cysts, thereby contributing to the existing body of knowledge pertinent to the diagnosis and therapeutic intervention s for this condition. A retrospective analysis was conducted on the clinical records of 23 pediatric patients diagnosed with testicular epidermoid cysts, who were admitted to our institution between April 2013 and February 2024. Concurrently, a comprehensive review and analysis of pertinent literature were undertaken to augment the findings. The mean age at which the onset of epidermoid cysts was observed was 6.0 years. All cases were singular and unilateral. B-ultrasound diagnosis categorized 6 cases as epidermoid cysts, 11 as teratomas, and 6 as indeterminate, yielding a diagnostic sensitivity of 26.1%. All patients underwent testicle-sparing mass resection, and nine patients underwent rapid intraoperative frozen section analysis, revealing eight cases of testicular epidermoid cysts and one teratoma, with a diagnostic sensitivity of 88.89%. Postoperative histopathological examination confirmed the diagnosis of testicular epidermoid cyst. Pediatric testicular epidermoid cysts are an uncommon occurrence, primarily presenting as a painless scrotal mass, which can mimic the clinical features of malignant testicular tumors. Imaging modalities and histopathological assessment are pivotal in the diagnostic process for pediatric testicular epidermoid cysts. For cases where B-ultrasound is inconclusive, rapid intraoperative pathological examination should be considered.

Testicular Epidermoid Cyst: A Rare Case Report.

Introduction an importanceTesticular epidermoid cysts (TECs) are rare benign testicular neoplasms. Recently, testicular epidermoid cysts (TECs) are listed as teratoma of prepubertal type, however it is still difficult to differentiate the epidermoid cyst from malign testicular tumor. Therefore, we would like to report testicular epidermoid cyst at our institution.Case presentationA 67-year-old man from Indonesia, presented with chronical painless mass of testis since one year ago. On physical examination obtained normal penile structure with descended testicles, palpable intrascrotal mass with size of 10 × 7 × 5 cm, firm consistency, immobile, without any tenderness, and no lymphadenophaty in groin. Scrotal USG showed intratesticular mass, homogenous parenchym, showed no vascularization during Doppler examination. Histopathological examination revealed the specimen of right scrotum with size of 12.5 cm × 8.5 cm × 6.1 cm with red-brownish colored, during lamellation, obtained encapsulated mass with size of 12.2 cm × 7.9 cm × 6 cm, hollowed space filled with porridge-like texture with capsule thickness of 0.1–0.3 cm.Clinical discussionEpidermoid cysts are benign lesions occurring on the skin usually, however, it rarely occurs in intratesticular area. Most of the cases (60%) presented with the typical onion-ring phenomenon. Histopathological findings commonly revealed typical well-defined cyst lined by a fibrous membrane. No skin appendages are found in the cyst's lumen and no germ cell neoplasm (GCN) is present in the adjacent testicular parenchyma.ConclusionAll testicular masses are considered malignant until proven otherwise. It is necessary to do accurate diagnosis for the prevention of unnecessary radical orchiectomy.

Testicular epidermoid cyst: a case report and review

Testicular epidermoid cyst: a case report and review

Testicular epidermoid cyst: about a case report and a review of the literature

BackgroundThe testicular epidermoid cyst is an exceptional benign tumor. The presumptive diagnosis is facilitated by the development of medical imaging (echo-Doppler, elastography, contrast-enhanced ultrasound, MRI). The confirmatory diagnosis is histological.Case presentationWe report the case report of a 37-year-old man who had a history of repetitive orchitis. He had complained of right scrotal discomfort for 6 months with no associated urinary symptoms. We performed an extemporaneous biopsy given the uncertain diagnosis (Fig. 3), and the histological examination was in favor of a mature teratoma. This prompted us to perform a right orchidectomy. The postoperative was simple. The final histological examination tipped in favor of an epidermoid cyst of the testicle. The patient was seen again at one month, and his clinical examination was normal.ConclusionThe testicular epidermal cyst is a rare benign tumor of the testicle. Currently, conservative surgery has become the gold standard thanks to the development of medical imaging to differentiate between the both forms of TEC, and it retains certain limits which lie in the differential diagnosis with the teratoma requiring large multicenter studies to better characterize these two entities.

MRI findings of an atypical testicular epidermoid cyst

Introduction:Typical testicular epidermoid cysts (TECs) manifestate as a target sign or onion skin sign on ultrasonography and magnetic resonance (MR) imaging. Clinicians are increasingly aware of the imaging characteristics of typical TECs, which allow accurate diagnosis and successful treatment while preserving the testicle, but atypical TECs are likely to be misdiagnosed as a malignant intratesticular neoplasm, leading to complete testicular resection.Patient concerns:A 26 year-old male patient complained of a painless enlargement of the left testicle that had been present for 1 month. The patient had no recent medical history of scrotal trauma or systemic infection.Diagnosis:A round 48 mm × 45 mm × 43 mm mass was seen inside the left testicle. T2-weighted images of the lesion showed a thin hypointense capsule. T1-weighted images of the lesion showed a hyperintense nodule on the cyst wall, which appeared hypointense on T2-weighted and SPAIR images. After Gd-DTPA injection, the lesion was not enhanced; however, the nodule was enhanced on THRIVE images. These manifestations were consistent with a benign intratesticular lesion, and MR imaging diagnosed atypical TEC, which was confirmed by pathology after surgery.Interventions:The patient was treated with organ-sparing surgery with testicular enucleation.Outcomes:The patient was re-examined with ultrasonography 3 months after surgery. The left residual testicular tissue appeared normal, and reproductive function was preserved.Conclusion:Urologists must be aware of the clinical and MR imaging characteristics of atypical TECs and the utility of preoperative MR imaging for the diagnosis of testicular lesions to ensure that organ-sparing surgery is performed rather than unnecessary orchiectomy.

A synchronous occurrence of bifocal intracranial germinoma and bilateral testicular epidermoid cyst in an adolescent patient with Klinefelter`s syndrome

Özyörük D, Kocayozgat A, Yaman-Bajin İ, Çetindağ F, Oğuz- Erdoğan AS, Güneş A. A synchronous occurrence of bifocal intracranial germinoma and bilateral testicular epidermoid cyst in an adolescent patient with Klinefelter`s syndrome. Turk J Pediatr 2019; 61: 456-459. Klinefelter syndrome (KS) is characterized by an additional X chromosome in males leading to a karyotype of 47,XXY. It is associated with an increased risk of certain malignancies, including leukemia, breast cancer and extragonadal germ cell tumor such as mediastinal germ cell tumors and rarely intracranial germ cell tumors. It is possible that the increased risk of developing certain cancers can be attributed to a direct effect of the chromosomal abnormality or the combined action of the abnormal chromosomes and hormonal imbalances. Here we describe a synchronous occurrence of bifocal intracranial germinoma and bilateral testicular epidermoid cyst in an adolescent patient with Klinefelter`s syndrome. The synchronous occurrence of the dual tumors in this patient with Klinefelter`s syndrome might be resulted from the migration defect during embriyogenesis due to underlying genetic disease or it is a coincidental condition, yet there has been no case reported in the literature, so far.

A rare case of bilateral testicular epidermoid cysts in a patient with Klinefelter's syndrome

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Testicular Epidermoid Cyst: Case Report and Literature Review

Introduction: Testicular epidermoid cysts are extremely uncommon. They are considered as benign tumors. Although an inguinal orchiectomy is the standard procedure for testicular tumors, if the presence of an epidermoid cyst is suspected, a conservative treatment may be attempted.

Case of testicular epidermoid cyst: Sonographic and histopathologic findings

Testikuler epidermoid kist benign, non-teratomatoz bir tumordur. Hastalar tipik olarak agrisiz ve hassas olmayan testikuler kitle ile basvururlar. Preoperatif ultrasonografi, normal biyokimyasal tumor belirtecleri ile birlikte baslica tani prosedurudur. Kesin tani histopatolojiktir. Bu olgu sunumunda inguinal orsiektomiye giden 27 yasindaki bir epidermoid kist hastasinin sonografik ve histopatolojik bulgularini sunduk.

Imaging in testicular epidermoid cysts

ObjectiveTo evaluate the utility of findings on ultrasound and magnetic resonance imaging (MRI) for the preoperative diagnosis of testicular epidermoid cysts (TEC). MethodsThe medical records of five patients treated for TEC at our institution between July 2010 and May 2017 were retrospectively reviewed. ResultsImaging revealed a target or onion skin appearance on ultrasonography and MRI. Pathological examinations showed “bread slag-like” materials within the TEC. Lesions failed to demonstrate enhancement after Gd-DTPA injection. ConclusionIn the cases of TEC in the current study, accurate diagnosis ensured enucleation of the testicular cyst was performed rather than testicular resection.

Testicular Epidermoid Cyst: A Case Report.

Epidermal cysts are the most common skin benign epithelial cysts. Most epidermal cysts occur in the skin of the head, neck, ear, face, and back. Testicular epidermoid cyst is very rare. We presented a 70-yearold man with testicular epidermoid cyst in this report.

Testicular Epidermoid Cyst: Case Report and Literature Review

Testicular epidermoid cysts are extremely uncommon. They are considered as benign tumors. Although an inguinal orchiectomy is the standard procedure for testicular tumors, if the presence of an epidermoid cyst is suspected, a conservative treatment may be attempted.

Cytodiagnosis of a testicular epidermoid cyst in a young male: A rare entity.

Intratesticular epidermoid cyst is a rare benign lesion of testis. It is important to distinguish this benign lesion from malignant testicular tumor . This is a case report of a 18yr old patient who presented with a mass in the left testis. His ultrasound showed typical onion skin appearance and tumour markers were within normal limits. Subsequently FNAC was performed which showed anucleated clumps of squamous epithelial cells admixed with the native testicular cells, thus diagnosis of testicular epidermoid cyst was made. Cytology along with sonographic findings provide rapid diagnosis and patient can be relieved of unnecessary anxiety. DOI: 10.21276/APALM.1152

Intra-testicular epidermoid cyst: a rare case report with clinico-radiological dilemma

Intra-testicular epidermoid cyst of testis is a benign tumour and accounts for 1-2% of all testicular neoplasms. It is a benign lesion, and should be distinguished from dermoid cyst or teratoma, which have a considerable malignant potential. We describe a rare case of testicular epidermoid cyst in an elderly male presenting with gradually increasing testicular mass since 8 months. Local examination revealed a non-tender, irregular, hard mass in the right testis. All routine laboratory investigations along with tumour markers were within normal limits. Ultrasound showed features of a testicular neoplasm following which orchidectomy was performed. Grossly, cut surface of testis showed a cyst measuring 4x2x1cm and microscopic examination revealed features of an epidermoid cyst. Extesive sampling excluded the possibility of a teratomatous focus. This case is described owing to the rarity of this neoplasm and the unusual clinico-radiological presentation. The pre-operative diagnosis of this tumour can be made if characteristic sonographic and MRI findings are obtained in the absence of which these masquerade neoplastic lesions. Histopathological examination thus is vital for a decisive diagnosis.

A Case of Testicular Epidermoid Cyst with Blood Flow Signal

A Case of Testicular Epidermoid Cyst with Blood Flow Signal

Testis-sparing surgery in testicular mass: Testicular epidermoid cysts

We present 3 patients with testicular epidermoid cysts who experienced testis-sparing surgery. These patients had a palpable painless testicular mass and underwent inguinal testicular exploration. Intraoperative frozen section revealed no evidence of malignancy and therefore enucleation of the tumour was performed. We demonstrate that careful intraoperative frozen-section examination helps to avoid unnecessary orchidectomy in testicular epidermoid cysts.

Epidermoid cyst of the testis

Testicular epidermoid cysts are rare, benign, keratin-containing intratesticular neoplasms. Preoperative sonography and biopsy are important criteria for the selection of testicular-preserving operations. More than 300 cases of testicular epidermoid cysts have been reported in the literature. We present a case of a 23-year-old man who complained of an asymptomatic right testicular mass, which, when examined, was found to be a firm, small-sized, mass lesion with a smooth surface. On ultrasonography, this mass appeared as a heterogeneous and well-demarcated intratesticular lesion. All laboratory investigations, including tumor markers, were normal. Histological diagnosis was an epidermoid cyst of the testis, and the obtained testicular tissue was normal.

Testicular epidermoid cysts in children: sonographic characteristics with pathological correlation

Testicular epidermoid cysts in children: sonographic characteristics with pathological correlation

Features of Testicular Epidermoid Cysts on Contrast-Enhanced Sonography and Real-time Tissue Elastography

A series of 7 testicular epidermoid cysts were imaged by contrast-enhanced sonography to assess internal vascularity and by real-time tissue elastography to grade stiffness by a visual and strain ratio quantification scoring system. No internal vascular enhancement was seen on contrast-enhanced sonography; the 3 largest lesions showed rim enhancement. On the real-time elastographic color display, all lesions were predominantly blue ("hard"), and the lesions analyzed for the strain ratio had a mean value of 43.57. Contrast-enhanced sonography depicts the absence of vascular flow, and real-time elastography shows that the epidermoid cysts are hard. This combination of information will help further characterize these lesions.

Testicular epidermoid cyst - Ultrasound and MR typical findings with macroscopy correlation

Figure 1 a. Longitudinal US image of the right testis show a bilobulated mass in the upper medial aspect of the testis. The mass had sharp margins, composed of a central echogenic area and of alternating hyperechogenic and hypoechogenic rings in the periphery (onionskin sign), measuring 2.4 x 1.7 x 1.7 cm. b. Longitudinal Doppler-US image of the right testis demonstrates the absence of vascularization of the mass. Ultrasound (US) revealed a solid mass in the upper pole of the right testis that was well circumscribed, avascular, and displayed the onionskin appearance suggestive of testicular epidermoid cyst (1,2) (Figure-1). Magnetic resonance (MR) confirmed the well-circumscribed intra-testicular mass with a