Test Device Research Articles

Navigation Training for Persons With Visual Disability Through Multisensory Assistive Technology: Mixed Methods Experimental Study

Background Visual disability is a growing problem for many middle-aged and older adults. Conventional mobility aids, such as white canes and guide dogs, have notable limitations that have led to increasing interest in electronic travel aids (ETAs). Despite remarkable progress, current ETAs lack empirical evidence and realistic testing environments and often focus on the substitution or augmentation of a single sense. Objective This study aims to (1) establish a novel virtual reality (VR) environment to test the efficacy of ETAs in complex urban environments for a simulated visual impairment (VI) and (2) evaluate the impact of haptic and audio feedback, individually and combined, on navigation performance, movement behavior, and perception. Through this study, we aim to address gaps to advance the pragmatic development of assistive technologies (ATs) for persons with VI. Methods The VR platform was designed to resemble a subway station environment with the most common challenges faced by persons with VI during navigation. This environment was used to test our multisensory, AT-integrated VR platform among 72 healthy participants performing an obstacle avoidance task while experiencing symptoms of VI. Each participant performed the task 4 times: once with haptic feedback, once with audio feedback, once with both feedback types, and once without any feedback. Data analysis encompassed metrics such as completion time, head and body orientation, and trajectory length and smoothness. To evaluate the effectiveness and interaction of the 2 feedback modalities, we conducted a 2-way repeated measures ANOVA on continuous metrics and a Scheirer-Ray-Hare test on discrete ones. We also conducted a descriptive statistical analysis of participants’ answers to a questionnaire, assessing their experience and preference for feedback modalities. Results Results from our study showed that haptic feedback significantly reduced collisions (P=.05) and the variability of the pitch angle of the head (P=.02). Audio feedback improved trajectory smoothness (P=.006) and mitigated the increase in the trajectory length from haptic feedback alone (P=.04). Participants reported a high level of engagement during the experiment (52/72, 72%) and found it interesting (42/72, 58%). However, when it came to feedback preferences, less than half of the participants (29/72, 40%) favored combined feedback modalities. This indicates that a majority preferred dedicated single modalities over combined ones. Conclusions AT is crucial for individuals with VI; however, it often lacks user-centered design principles. Research should prioritize consumer-oriented methodologies, testing devices in a staged manner with progression toward more realistic, ecologically valid settings to ensure safety. Our multisensory, AT-integrated VR system takes a holistic approach, offering a first step toward enhancing users’ spatial awareness, promoting safer mobility, and holds potential for applications in medical treatment, training, and rehabilitation. Technological advancements can further refine such devices, significantly improving independence and quality of life for those with VI.

Assessment of non-destructive nuclear and non-nuclear asphalt density testing devices for Australian road construction

ABSTRACT Non-nuclear density gauges, also known as Pavement Quality Indicators (PQIs), offer several advantages over widely used destructive test methods and nuclear density gauges (NDGs) for asphalt density measurement. Replacing NDGs with PQIs would simplify regulatory requirements and reduce the cost and complexity of in-situ asphalt density measurement. This is due to the absence of nuclear materials and the ability of PQIs to provide measurements rapidly. However, PQIs have not gained widespread use in Australia due to concerns regarding accuracy. This work assesses the suitability of PQIs for both acceptance and quality control testing by analysing a dataset collected over an extended period and across a wide range of construction sites in Australia. Accuracy was evaluated based on the strength of the relationship between gauge measurements and core density results. Although some evidence supporting the use of PQIs for quality control purposes has been found, their use for acceptance testing remains unwarranted. Recommendations for establishing standard testing methods are provided to encourage wider adoption of PQIs.

Tribological properties of dual-freedom sliding roller pairs with a loss of lubrication

Purpose This paper aims to design a novel test device and study the wear properties and the thermal mechanisms of roller pairs in dual-freedom sliding contacts. Design/methodology/approach On the transition process of lubrication regimes, experiments were conducted with various values of running speed and slip ratio obtained by two motorized spindles. Temperature and surviving time would be obtained of GCr15/GCr15 and DLC/GCr15 friction pairs. Micro photography was obtained with a PGI 3D stylus profiler and a confocal microscopy OLS4000-3D. An empirical mode decomposition method was used to eliminate measure errors. Findings Results showed that, even with little initial lubricant, rolling/sliding pairs still rotated for a certain time. With the synthetic actions of the dual-freedom sliding, the loss of lubrication and the tilt, interesting helical grooves appeared. Sliding speeds had remarkable effects on survive time, temperatures and surface topographies. In addition, the equilibrium values of the temperature and the surface roughness were obtained in sufficient oil supply. Extreme wear-out conditions were obtained with starved lubrication. Diamond-like carbon coatings showed better heat resistance and better wear resistance. Originality/value This work would be critical for the life design and the heat treatment of rolling bearings in the full flood lubrication and the starved lubrication. Peer review The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-05-2024-0164/

Abstract 4145821: Serial Vascular Responses of Balloon-expandable Stent with Biodegradable Film-type Graft in a Rabbit Iliac Artery Dissection Model (BioGard Study)

Introduction and Background: Arterial dissection during endovascular therapy rarely occurs but can be lethal. A significant blood volume extravasation during coronary artery interventions is related to the very high mortality (20-30%). In this hyperacute emergent clinical situation, covered stents have been considered as a primary measure to prevent further serious arterial events. A fabric-based covered graft stents yield poor clinical outcomes. To overcome these challenges, the balloon-expandable stent with biodegradable film-type graft for treating arterial dissection was invented. Research Questions and Objectives: A novel balloon-expandable stent with biodegradable film graft for overcoming these issues would be valid for efficacy and safety in a rabbit iliac artery dissection model. Method and Approach: Eighteen iliac artery dissections were induced by balloon over-inflation on angiography (Ellis type 2 or 3) and treated using the test device (3.0 x 24 mm). Subsequently, twelve animals underwent histologic examinations and micro-computed tomography (CT) at 0, 2, 4, and 8 weeks and 3, 6, 9, and 12 months and angiography at one-year. Results and Data: There were no adverse cardiovascular events during the one-year. Early-stage histologic examination revealed complete sealing of disrupted vessels by the device, exhibiting mural hematoma, peri-stent red thrombi, and dense infiltration of inflammatory cells. Mid- and long-term histologic examination showed patent stents with neointimal hyperplasia over the stents (% area stenosis: 11.8 at 2weeks, 26.1 at 1month, 29.7 at 3months, 49.2 at 9months, and 51.0 at 1year), along with mild peri-strut inflammatory response (Grade: 1-2 at mid-term and 0-1 at long-term). The graft film became scarcely visible after six months. Both CT and angiography revealed no instances of thrombotic occlusion or in-stent restenosis (% diameter stenosis: 5.7 at 2weeks, 12.3 at 1month, 14.2 at 3months, 25.1 at 9months, and 26.6 at 1 year). Conclusion: The novel balloon-expandable stent with a biodegradable film graft demonstrates feasibility in managing severe artery dissection and preventing lethal vascular events in animal model. Future human studies are warranted to validate these findings and elucidate the clinical outcomes of the study.

Analysis of failure modes and impact resistance factors of PDC cutters

The service life of PDC cutters directly affects the overall drilling performance. In hard and heterogeneous formations, PDC cutters often fail prematurely due to dynamic impacts, leading to short footage and slow penetration rates. Enhancing the dynamic impact resistance of PDC cutters is crucial for achieving one-run drilling and reducing costs. This paper systematically studies the main factors influencing and optimizing the impact resistance of PDC cutters. First, the failure modes of hundreds of returned PDC drill bits were statistically analyzed, revealing that dynamic impact failure, wear failure, thermal damage, and erosion are the primary failure modes. Among these, dynamic impact failure is the most prevalent, with dynamic impact load being the main cause. Following the successful practices of leading international drill bit companies, a set of dynamic impact test and evaluation devices for PDC cutters was designed, and corresponding testing standards were established. Based on this, 19 types of PDC cutters were tested for impact resistance, exploring the effects of cutter diameter, diamond layer thickness, chamfer, cobalt removal, and cutter design on impact resistance. An optimized design methodology to enhance impact resistance was summarized, leading to the proposal of a new arch-axe cutter design. Indoor impact test data verified the superiority of this cutter. The research results indicate that cutter design (non-standard cutters) can significantly improve the dynamic impact resistance of PDC cutters. Additionally, increasing the cutter diameter and chamfer size while reducing the diamond layer thickness also enhances the dynamic impact resistance of PDC cutters. Through the optimization of the arch-ridge design, the independently developed arch-axe cutter improved the dynamic impact resistance by 106.45% and 71.43% compared to flat circular cutters and axe-shaped cutters, respectively.

Progressive development of soil arching and deformations in two- and three-dimensional trapdoor tests

In this study, two- and three-dimensional trapdoor tests were conducted using a newly developed trapdoor test device, to investigate the evolution of soil arching and fill deformation with different relative fill densities and fill heights. The test results show that the trapdoor settlements normalised by trapdoor width required for the soil arching ratios to reach minimum and ultimate values increased with fill height. In tests with dense fill, both the minimum and ultimate soil arching ratios were smaller compared to tests with loose fill at the same fill height. Two symmetrical slip surfaces developed from the trapdoor edges, with their inclination angles dependent on the dilatation angle of the sand. The proposed Gaussian distribution function with fitting parameters well matched the measured fill settlement profile. In the dense fill tests, the settlement trough’s width and volume loss induced by trapdoor settlement gradually decreased with fill elevation due to its strong shear dilation behaviour. Conversely, the loose fill exhibited weaker shear dilation behaviour, resulting in a larger settlement region. The settlement trough width and volume loss ratio, derived from the measured fill deformation, can be used to predict the fill deformation, including the surface settlement.

Design and study of a novel rotary high-impact test device

Abstract Impact testing is an important means of evaluating an object’s ability to withstand impacts at specific peak accelerations. Currently, commonly used high-g impact testing devices, such as the Mach hammer and air cannon test devices, generally provide overloads ranging from 10, 000g to 30, 000 g, with a maximum of 50, 000 g. To meet the demand for high-overload impact collisions, this paper designs and studies a high-g long pulse width rotary impact test device with a detachable impact head. A finite element simulation model of the impact process was established by using finite element analysis software, and the dynamic response of the device was studied by changing the initial rotation speed and the target plate material. The results show that the overload of this rotary impact test device can reach more than 70, 000 g, and increasing the speed and hardness of the target plate material can improve the overload magnitude. This device and research method can provide theoretical support for high-overload impact testing.

Clinical Accuracy of the G.LAB MD41A0 Upper Arm Blood Pressure Monitor in Pregnancy and Pre-Eclampsia Using the AAMI/ESH/ISO as Reference Standard.

Validation of blood pressure (BP) monitors in pregnant women are needed to ensure the accurate measurement of BP in pregnancy. Therefore the study aimed to evaluate the measurement accuracy of the G.LAB MD41A0 oscillometric automatic upper-arm blood pressure monitor in pregnancy and pre-eclampsia women according to the AAMI/ESH/ISO Universal Standard (ISO 81060-2:2018). A total of 45 pregnant women were included in the cross-sectional validation study. The same left-arm sequential method was used for blood pressure measurement, and the blood pressure differences between the test device and the mercury standard reference were assessed according to the AAMI/ESH/ISO Universal Standard. The participants included 15 normotensives, 15 gestational hypertension and 15 pre-eclampsia. The average (mean ± SD) differences between the device and mercury standard was -0.84±3.88mmHg and -0.58±3.35mmHg for systolic and diastolic blood pressure, respectively, for the validation Criterion 1. The SD of the averaged differences between the device and reference readings per participant was 2.92mmHg and 2.28mmHg for systolic and diastolic blood pressure, respectively, for the Criterion 2 of the universal standard. The G.LAB MD41A0 automatic upper-arm blood pressure monitor fulfills the criteria of the AAMI/ESH/ISO Universal Standard and can be recommended for clinical use and self-measurement in pregnancy and pre-eclampsia.

Numerical Simulation of Solid Diverting Particles Transport and Plugging in Large-Scale Hydraulic Fracture

Diversion technology, also known as temporary plugging technology, has become an integral part of hydraulic fracturing in unconventional reservoirs. The solid diverting particles are a common type of chemical diverting agents used in horizontal well multistage fracturing. The transport and plugging of solid diverting particles within the fractures are crucial physical processes in the far-field diversion technology. In this study, in order to clarify the formation of the plugging layer by solid diverting particles in large-scale hydraulic fracture and to offer insights for the quantitative optimization of far-field diversion technology (FFD), an enhanced simplified two-fluid model within the Euler-Euler framework is employed to simulate the transport and plugging process of solid diverting particles within the fracture. And the numerical schemes of the front settlement region, the plugging layer formation region and the rear settlement region are also optimized. The proposed model is verified through comparison with experimental results from visual fracture test device. Based on the numerical results across various particle, pumping and fracture parameters, our findings indicate that: (1) The duration required to form a complete plugging layer can be reduced to 3% to 20% by increasing injection concentration, injection rate, and fracturing fluid viscosity; (2) Increasing the injection concentration (from 10kg/m3 to 30kg/m3) significantly enhances the length of the plugging layer by about 1 to 16 times, compensating for the inability to achieve a complete plugging layer with smaller particle sizes. Merely increasing the injection rate alone (from 0.35m3/min to 0.80m3/min) does not remedy the inability of small particles to form a complete plugging layer under identical plugging conditions. Excessive fracturing fluid viscosity (higher than 6mPa·s) impedes the formation of a complete plugging layer with smaller particles. High fracturing fluid leak-off rate (higher than 2.5×10-7m/s) markedly reduces the length of the plugging layer by about 37% to 44%; (3) Achieving a high close packing degree of particles within the plugging layer is facilitated by increasing injection concentration, increasing injection rate, and reducing fluid viscosity; (4) The abrupt variation in fracture width or height along the fracture length affects up to about 18% of the length of the plugging layer at the top of fracture. To ensure large length of the plugging layer at the top of fracture and high close packing degree of particles within the plugging layer, we recommend injection concentration above 10kg/m3, fracturing fluid viscosity below 6mPa·s, and injection rate exceeding 0.35m3/min. For particle size less than 1.8mm, we suggest injection concentration above 20kg/m3, and fracturing fluid viscosity not exceeding 3mPa·s.

Agreement and Reliability of Transpalpebral Tonometers with Goldmann Applanation Tonometer – A Systematic Review and Meta-Analysis

TopicThe systematic review and meta-analysis consolidates the extant body of evidence comparing reliability and agreement between Transpalpebral Tonometers (TT) and Goldmann Applanation Tonometer (GAT). Clinical RelevanceWith a global prevalence of 3.54 percent, glaucoma stands as the second leading cause of preventable blindness. Projections indicate a rise to 111 million cases by 2040. Existing literature presents inconsistent findings while comparing TT and GAT. The derivation of summary estimates assessing their agreement holds significance given TT’s multifaceted applicability in clinical, community, and home settings. MethodsSystematic review was conducted using PubMed, Cochrane Library, and Google Scholar from January 2000 to December 2022. Two reviewers independently evaluated, enumerated, and extracted studies and data based on eligibility criteria. The Quality Assessment for Diagnostic Accuracy Studies (QUADAS-2) checklist was used to assess study quality. The summary measures were pooled using the random effects model as mean difference (MD), and 95% LoA (Limits of Agreement). We assessed heterogeneity using the I2 statistic. The study protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO - CRD42022321693). ResultsA total of 26 methods comparison studies (3577 eyes) were included in the meta-analysis. The overall random-effects MD (TT – GAT), SD and 95% LoA for IOP were -0.70 ± 4.15 mmHg (-8.83 to 7.43 mmHg). In the subgroup analysis based on index test devices used, Easyton showed the lowest MD, SD (-0.29 ± 2.35 mmHg), and 95% LoA (-4.90 to 4.32 mmHg). In the univariate meta-regression model, we found that, on average, studies examining normal eyes reported a statistically significant lower mean difference of 2.67 mmHg (95% CI: 0.27 to 5.07 mmHg; P = 0.03) between TT and GAT, compared to studies that assessed eyes with mixed ocular condition. ConclusionIn the current meta-analysis, we found a small MD in the measured IOP between the two tonometers. However, given the high heterogeneity and a wider LoA, it is not advisable to use TT interchangeably with GAT.

The Photometric Testing of High-Resolution Digital Cameras from Smartphones-A Pilot Study.

Luminance is the fundamental photometric quantity representing the technical meaning of brightness. It is usually measured from a distance using a matrix sensor, which is the basis of the professional instrument. However, specific technical requirements must be fulfilled to achieve accurate results. This paper considers whether modern high-resolution smartphone cameras are suitable for luminance measurements. Three cameras from high-end smartphones were evaluated on a dedicated laboratory stand. The sensors' output characteristics showed relatively good linearity of the individual R, G, and B channels. Unfortunately, the spectral sensitivities were unfavorable, as the minimum error achieved was about 17%. This device is classified outside the generally accepted quality scale for photometric instruments. The presented investigation confirmed that none of the high-resolution smartphone cameras tested was suitable for use as a universal luminance camera. However, one of the test devices can be developmental if restrictively calibrated and used only in a specialistic laboratory stand. Using a smartphone (or only its camera) for luminance measurements requires proper advanced calibration. It is possible, but it limits us to only dedicated applications. The pilot study presented in this paper will help create a suitable test stand for spectacle vision systems, e.g., virtual reality equipment.

Optimisation of artefact detection in photoplethysmography heart rate data: influence of different classifiers in machine learning models

Abstract Background Heart rate (HR) tracking by wrist-worn devices using photoplethysmography (PPG) could assist in continuously following up physical activity. However, the accuracy can be impacted by (motion) artefacts. Machine learning models could help to recognise artefacts in PPG-based HR data. The choice of classifier in these machine learning models is a determing factor for task performance of the model. Purpose This study evaluates and determines the optimal classifier for a new machine learning-based approach to enhance the reliability of artefact detection in PPG-based HR data. Methods A total of 62 participants (27 cardiac rehabilitation patients, 35 healthy athletes) wore both a test device and a reference device measuring HR continuously for 24 hours. A training dataset was prepared, assigning two independent labels (i.e. anomaly and activity) to each HR episode based on the reference device data. Fitbit data were processed using our in-house designed artefact removal procedure, which involves the application of two classification models: one for anomaly detection and another for activity detection. Four distinct classifiers were employed for both models: Balanced Bagging, Balanced Bagging with Random Forest, Balanced Random Forest, and Logistic Regression. Each classifier was evaluated using area under the receiver operating characteristic curve (ROC-AUC), accuracy, sensitivity and specificity. Results Of the 1,647,328 HR data points collected, 103,095 (6.26%) were identified as artefacts. Figure 1 and Figure 2 summarise the performance of the distinct classifiers for the anomaly model and the activity model, respectively. Balanced Bagging and Balanced Bagging with Random Forest consistently demonstrate the highest AUC values and accuracies across both anomaly and activity detection models (anomaly detection: AUC = 0.95, accuracy = 89-85%; activity detection: AUC = 0.98, accuracy = 95%). Comparing these two, Balanced Bagging with Random Forest emerges as the preferred option, given the highest sensitivity in both anomaly detection (93%>86%) and activity detection models (99%>96%). In contrast, Balanced Random Forest and Logistic Regression exhibit inferior performance. In the anomaly detection model, Balanced Random Forest exhibits a lower sensitivity of 75%, while Logistic Regression performs even worse with a sensitivity of 25%. Similarly, in the activity detection model, both Balanced Random Forest and Logistic Regression demonstrate diminished performance. Conclusions Balanced Bagging with Random Forest emerges as the optimal classifier to detect anomalies and activities in continuous PPG-based HR data, thus contributing to the optimisation of our in-house designed procedure for removing artefacts. This processing aims to provide a reliable and automatic way for continuous HR monitoring, which can help monitor and guide physical activities.

Potassium Fertilizer Application Rates for Fertigated Edamame Grown on Low-K Soils

Edamame, a legume consumed fresh as a vegetable, is highly nutritious, particularly protein-rich, and holds significant economic value. However, its cultivation faces challenges, especially on dry land, due to water scarcity and limited nutrient availability, particularly potassium (K). This study, which investigated the impact of potassium fertilization rate on edamame cultivation, underscores the need for further research. The study utilized a single factor, potassium fertilization rate, arranged in a completely randomized block design. Potassium rates consist of 0% X, 50% X, 100% X, 150% X, and 200% X, where X represents the recommended potassium fertilization rate according to the dry soil test device (DSTD) guidelines. Each treatment was replicated five times. Data were analyzed using ANOVA at a 5% significance level, and any significant effects were further examined using orthogonal polynomial and regression analysis. The results indicated that potassium fertilizer rates did not significantly affect edamame height, pod weight per plot, and marketable yield. However, the study identified the optimal potassium fertilizer rate, which was between 83%X and 119%X, equivalent to 83–119 kg.ha⁻¹ of KCl (50–72 kg.ha⁻¹ of K₂O). This range positively increased total branch yield, productive branches, number of flowers, pod weight per plant, number of pods per plant, and plant dry weight, producing a quadratic response pattern. The study recommends further research to optimize potassium fertilizer doses based on DSTD recommendations, particularly at a low K nutrient status, to maximize marketable yields through fertigation.

Study on the strength influence mechanism and cracking mechanism of stone powder-cement floor grouting materials

Underground grouting is a concealed project, and it is difficult to test the strength of grouting stones in engineering practice. Aiming at the problems of high confined water pressure and strong water-richness of the roadway floor, a pressure filtration test device was developed, and a PFC2D uniaxial compression model was established to study the variation law of stone strength and crack evolution mechanism of grouting materials under different grouting pressures. The results show that with the increase of pressure filtration value, the amount of slurry dehydration increases, the pore water pressure dissipates, the pores between particles are tightly compressed, the contact force between particle skeletons increases, and the strength of stone body increases. Under the condition of the same cement powder ratio (mass ratio of cement to stone powder) or stone powder particle size, the strength of stone body of stone powder-cement grouting material increases with the increase of pressure filtration value. The stress-strain curves of the stone body with different pressure filtration values all experienced three stages: continuous elasticity, fracture expansion and strength failure. Before the peak, the number of cracks increases slowly; after reaching the peak, the micro-cracks extend rapidly and the number increases rapidly, resulting in the final tensile failure of the specimen. This study can provide a basis for the selection of grouting engineering material ratio and grouting pressure parameters.

A novel model for low-permeability reservoir numerical simulation considering dynamic capillary force

ABSTRACT Capillary force is not only affected by water saturation but also affected by fluid flow velocity, which is necessary to modify the prior numerical simulation methods. First, a dynamic capillary force testing device was developed, then, an experimental procedure was adopted to measure the dynamic capillary force curve. Three dynamic capillary force curves were obtained under different displacement velocity conditions. Finally, the dynamic capillary force was introduced into the flow equation of low-permeability reservoir numerical simulation. The oil-phase equation and water-phase equation were discretized in three-dimensional space, and the IMPES method was used to solve the water saturation and pressure difference. The calculation results between the traditional numerical simulation method and the novel method under heterogeneous and inhomogeneous conditions were analyzed. The results reveal that the difference in water cut is mainly reflected in the rapid rise of water cut. In the early stage of rapid increase, the water cut calculated by the new method is slightly higher than traditional method. When the water cut is more than 65%, the water cut calculated by the new method is slightly lower than the traditional method.

The effect of different treatment protocols on shear bond strength in resin composite restoration repair

BackgroundIt was aimed to investigate the effect of sandblasting and laser surface treatment on shear bond strength in composite restoration repair in vitro.MethodsA micro-hybrid composite (Filtek Z250, 3 M-ESPE, USA) was used to prepare 120 samples. The samples were subjected to a thermal cycle test 5,000 times between 5 and 55 0C, and they were randomly divided into 12 groups (n = 10). No surface treatment was performed in Groups 1 to 4, which were designed as control groups. The surfaces of the samples in Groups 5 to 8 were sandblasted with a Cojet device, and the surfaces of the samples in Groups 9 to 12 were applied Er, Cr: YSGG laser. After the sample surfaces were divided into groups with and without acid etching, universal adhesive was applied, and the repair process was performed using Filtek Z250 or nano-filled resin composite (Filtek Ultimate, 3 M-ESPE, USA). The thermal cycle test was repeated 5,000 times between 5 and 55 0C on all repaired samples. The repair shear bond strength of the samples was measured using a universal testing device (Shimadzu IG-IS, Kyoto, Japan). The fracture types were evaluated by optical microscopy and scanning electron microscopy (SEM). Statistical analyses of the findings were evaluated by the Kruskal Wallis test and Mann Whitney U test at 0.05 significance degree.ResultsThe highest mean shear bond strength values were obtained from the samples sandblasted with CoJet, followed by Er, Cr: YSGG laser, and the control group. It was determined that there was a significant difference between the mean shear bond strength values obtained from the control group and the other surface treatment groups (p < 0.05). In general, significantly higher mean shear bond strength values were obtained when the universal adhesive was applied in total-etch mode compared to the application in self-etch mode (p < 0.05). Additionally, it was determined that higher shear bond strength values were obtained with Filtek Ultimate compared to Filtek Z250 (p < 0.05).ConclusionWithin the limitations of this study, it can be concluded that the use of universal adhesive in total-etch mode, in addition to surface treatments on the resin composite surface in the repair protocol and the use of nano-filled resin composite as repair material can increase the mean shear bond values in repair.

The evaluation of a novel single-lead biopotential device for home sleep testing.

This paper reports on the clinical evaluation of the sleep staging performance of a novel single-lead biopotential device. 133 patients suspected of obstructive sleep apnea were included in a multi-site cohort. All patients underwent polysomnography and received the study device, a single-lead biopotential measurement device attached to the forehead. Clinical endpoint parameters were selected to evaluate the device's ability to determine sleep stages. Finally, the device's performance was compared to the clinical study results of comparable devices. Concurrent PSG and study device data were successfully acquired for 106 of the 133 included patients. The results of this study demonstrated significant similarity in overall sleep staging performance (5-stage Cohen's Kappa of 0.70) to the best-performing reduced-lead biopotential device to which it was compared (5-stage Cohen's Kappa of 0.73). Contrary to the comparator devices, the study device reported a higher Cohen's Kappa for REM (0.78) compared to N3 (0.61), which can be explained by its particular measuring electrode placement (diagonally across the lateral cross-section of the eye). This placement was optimized to ensure the polarity of rapid eye movements could be adequately captured, enhancing the capacity to discriminate between N3 and REM sleep when using only a single-lead setup. The results of this study demonstrate the feasibility of incorporating a single-lead biopotential extension in a reduced-channel home sleep apnea testing setup. Such incorporation could narrow the gap in the functionality of reduced-channel home sleep testing and in-lab polysomnography without compromising the patient's ease of use and comfort.

Assessment of diagnostic accuracy of Gazelle: A point-of-care testing device for screening β-thalassemia trait.

Background & objectives Timely detection of population with β-thalassemia trait (BTT) followed by genetic counselling is an advocated method of preventing the birth of a child with β-thalassemia major. In this study we aim to assess the diagnostic accuracy of Gazelle, a point-of-care (POC) testing device, in screening for BTT in hospital laboratory setting. Methods Standards for Reporting Diagnostic Accuracy (STARD) guidelines were followed in developing study design, recruiting study participants and sample size calculation for the current research. A consecutive sample of 446 participants was recruited for this study and was tested for the reference test Gazelle as well as the gold standard cation exchange high performance liquid chromatography (CE-HPLC). Low serum ferritin levels are known to interfere with the production of HbA2 and in turn lead to false negative results. Hence, the study population was divided into two categories with respect to a cut off value of 15ng/dl of serum ferritin and the results were analyzed. Results Overall diagnostic accuracy of Gazelle for detecting BTT was found to be 95.3 per cent with a confidence interval (CI) of (92.9 - 97.1) and the sensitivity was 94.5 per cent with a 95% CI of (84.8 - 98.8). When analyzed by the serum ferritin level the diagnostic accuracy was found to be 94.7 per cent (91.1% - 97.1%) and 95.7 per cent (91.8% - 98.1%) for participants with serum ferritin level as > 15 ng/ml and < 15 ng/ml, respectively. Interpretation & conclusions This study found Gazelle to be a good screening tool for β-thalassemia trait with high sensitivity, specificity and accuracy. However, it is recommended that the final confirmation of the diagnosis done by a diagnostic test like HPLC or Capillary Zone Electrophoresis (CZE).

Model test study on the dynamic failure process of tunnel surrounding rocks in jointed rock mass under explosive load

The presence of joints can significantly reduce the integrity and stability of an engineering rock mass. Under dynamic loads, such as from blasting excavation, the key blocks divided by joints may be destabilized and prone to sliding, potentially leading to engineering geological disasters like rockbursts. To study the dynamic instability process, similar materials for the rock mass and joints were developed based on the similarity theory, and a tunnel model in the jointed rock mass was constructed. Subsequently, a detonating fuse was used to generate a dynamic load, and the dynamic instability process of the tunnel surrounding rock in the jointed rock mass under explosive load was studied using the geotechnical multifunctional testing device. The deformation characteristics and dynamic instability process of the tunnel surrounding rock were analyzed using acceleration sensors, resistance strain gages, linear variable displacement transducers and motion camera. The study shows that the acceleration at the tunnel vault is significantly greater than at the straight wall and floor under blast loads, with differences reaching an order of magnitude. Acceleration waveforms were classified into three categories based on peak characteristics, explained through the propagation of explosive stress waves. Additionally, strain and displacement at the tunnel arch were also significantly greater than in other areas, indicating more severe stress concentration and dynamic damage at the arch, necessitating reinforced support in tunnel excavation. The entire dynamic instability process of the tunnel surrounding rock was successfully recorded using a motion camera. The dynamic failure process was divided into several phases, the appearance of cracks on the joint surface, particle ejection accompanied by the dropping of jointed blocks, a significant drop of the jointed blocks, and return to calm. The dynamic failure modes include the dropping and rotation of jointed blocks, local particle ejection, and shear cracks on jointed block.

Effects of radiotherapy dose and application time on the load-to-failure values of teeth filled with different sealers

BackgroundThe materials used in root canal filling and radiotherapy (RT) application can affect the load-to-failure of the teeth. This study aimed to compare the load-to-failure of the teeth filled with AH Plus (AHP) or AH Plus bioceramic (AHPB) before or after 60 Gy- and 70 Gy-dose radiotherapy.Materials and methodsOne hundred and ten maxillary incisors were endodontically prepared up to ProTaper Next X4 instruments. The teeth were randomly divided into 5 main groups as: non-irradiated, root canal treatment (RCT) before 60 Gy radiotherapy, RCT before 70 Gy radiotherapy, RCT after 60 Gy radiotherapy, RCT after 70 Gy radiotherapy. These groups were divided into 2 subgroups for filling material: AHP ve AHPB. After filling and radiotherapy procedures, the teeth were fixed on the thermoplastic mask plane. The plane were placed in the middle of a rectangular prism shaped glass phantom, and irradiated via a linear accelerator device. The teeth were then embedded in cylindrical acrylic blocks and the force (N) that caused the fracture was recorded under the Universal testing device. Student t-test was used for statistical comparisons. Statistical significance level was determined as p < 0.05.ResultsAfter 70 Gy dose radiotherapy, the group filled with AHPB showed statistically significantly lower fracture strength than the group filled with AHP (p < 0.05). In the control group, before 60 Gy RT group, after 60 Gy RT group, and before 70 Gy RT group, the sealers had statistically significantly similar load-to-failure. (p > 0.05).ConclusionThe group filled with AHPB caused a lower fracture strength than the group filled with AHP following a 70 Gy dose of RT. The sealers in the control group, before 60 Gy RT group, after 60 Gy RT group, and before 70 Gy RT group exhibited comparable load-to-failure values.