Abstract Purpose: The transition from 2-dimensional (2D) to 3-dimensional (3D) external beam radiation therapy (EBRT) can dramatically improve the quality of radiotherapy in low and middle-income countries (LMICs); however, many cancer centers in LMICs lack training support to effectively make this transition. Remote training is a low-cost, accessible option to bridge this gap, and we sought to evaluate the efficacy of such a program. Methods: The nonprofit Rayos Contra Cancer identified 9 LMIC operational cancer centers in the Middle East and Northern Africa that had recently acquired technology to transition from 2D to 3D EBRT. Baseline information for each center was collected electronically, then a team of EBRT content experts developed a 12-week, 25-session continuing medical education curriculum. Each session invited live participation using Zoom video communications and lasted 1 - 2 hours. Participants were administered a Likert scale (1-5) confidence evaluation on 13 foundational topics in 3D EBRT and a 49-point knowledge-based multiple-choice examination pre- and post- curriculum. Anonymous feedback with 1-5 satisfaction scores for each session was solicited midway and at the conclusion of the curriculum. Training was provided for free. Results: Among centers, 260 participants enrolled in training, including 39 medical physicists, 36 radiation oncologists, 54 radiation therapists, 15 dosimetrists, and 116 in training or other roles. Pre- and post-curriculum average examination scores were 22.95/49 (53.4%, N = 171) and 30.76/49 (62.8%, N=87), respectively. Pre- and post-curriculum confidence evaluation showed an average of 1.4/5 (27.7%, N=260) and 3.86 (77.2%, N=74) confidence among 13 topics. Satisfaction surveys (halfway N=51, end N=48) showed high satisfaction with helpfulness (4.3/5) enjoyableness (4.2/5), and well-preparedness (4.4/5) of sessions. Conclusion: Satisfaction, confidence, and knowledge domains were all measured with favorable results. This innovative low-cost telehealth model for EBRT training is a promising vehicle for advancing cancer care in LMICs by providing educational support. Citation Format: Fei Yang, Raymond Carter, Soha Ahmed, Tia Plautz, Piotr Dubrowski, Shada Wadi-Ramahi, Sarah Ashmeg, Frank Ascoli, Daniel Wakefield, Justus Adamson, Benjamin Li. A Longitudinal Telehealth Curriculum for Radiation Oncology Centers in Low and Middle-Income Countries Transitioning from 2D to 3D External Beam Radiation Therapy [abstract]. In: Proceedings of the 9th Annual Symposium on Global Cancer Research; Global Cancer Research and Control: Looking Back and Charting a Path Forward; 2021 Mar 10-11. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2021;30(7 Suppl):Abstract nr 109.
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