In this research, by using the finite element method, the effect of five parameters (density of a liquid mineral fertilizer (ρ), its temperature (T), tank wall thickness (L), spacing of stiffeners (K) and stiffeners height (h)) on the strength of standard polyethylene rotomolded tanks used for storage of liquid mineral fertilizers (LMF) was studied. Using the Taguchi method, it was found that these parameters are ranked according to the degree of their influence (in decreasing order) on: maximum stresses (r>L>h>T>K), maximum stresses in the tank walls (r>L>K>T>h) and deformations of the tank (for DX/DY: r>L>h>T>K and for DZ: r>L>h>K>T). Validation of the FEM strength calculations was carried out, which showed satisfactory convergence of the calculated and experimental values. Generalized equations are derived that describe the effect of all five studied parameters on P, PW and tank deformations (along the X, Y and Z axes). On the basis of the derived equations, a nomogram has been constructed, which makes it possible to choose the optimal wall thickness that will correspond to the LMF density and storage temperature. Applying the optimal wall thickness ensures a guaranteed service life of at least 50 years, minimizing the risk of environmental accidents caused by tank failure and the release of LMF and associated toxic substances into groundwater. This research offers valuable insights for designing safer and more durable storage tanks for liquid mineral fertilizers. As an optimal design of the tank for storing the most common fertilizer UAN-32 (Urea Ammonium Nitrate, 32 % nitrogen), with a density of 1.32 g/cm3 and at storage temperatures up to 40 °C, the following values of structural parameters are recommended: L=10 mm, K=38 mm, and h=4 mm