In this paper, a conformal T-shaped flexible patch antenna is designed for biomedical applications. The proposed antenna designed using to resonate at 2.45 GHz operating frequency at ISM band. The proposed antenna operates in free space and muscle tissue. The proposed T-shaped patch antenna in free space resonates at 2.47GHz operating frequency with a bandwidth of 300MHz (2.45GHz and 2.75GHz).The antenna implanted in muscle tissue operates at 2.47GHz frequency with a bandwidth of 600MHz (2.25GHz – 2.85GHz). The return loss of -13.04dB is observed for T-shaped patch antenna in free space and the return loss for the antenna implanted in human tissue is -20.6dB respectively. The proposed flexible conformal patch antenna is compact in size, efficient in functioning, safe, and can effectively work within specified medical frequency bands.