Context. Magnetohydrodynamic (MHD) turbulence plays a critical role in many key astrophysical processes, such as star formation, acceleration of cosmic rays, and heat conduction. However, its properties are still poorly understood. Aims. In this work, we explore how to extract the intermittency of compressible MHD turbulence from synthetic and real observations. Methods. We used three statistical methods, namely the probability distribution function, kurtosis, and scaling exponent of the multi-order structure function, to reveal the intermittency of MHD turbulence. Results. Our numerical results demonstrate that: (1) the synchrotron polarization intensity statistics can be used to probe the intermittency of magnetic turbulence, by which we can distinguish different turbulence regimes; (2) the intermittency of MHD turbulence is dominated by the slow mode in the sub-Alfvénic turbulence regime; and (3) the Galactic interstellar medium (ISM) in the low latitude region corresponds to the sub-Alfvénic and supersonic turbulence regime. Conclusions.We have successfully measured the intermittency of the Galactic ISM from synthetic and realistic observations.