Synthetic 3D Research Articles

Galvanic distortion decomposition of magnetotelluric impedance tensors in 1D electrical anisotropic media

Summary The electromagnetic (EM) local distortion of the transfer function due to shallow small-scale inhomogeneities hinders the accurate interpretation of magnetotelluric (MT) data. Under the assumption that regional subsurface structures are electrically isotropic, decomposition techniques of the MT impedance tensor that focus on the galvanic distortion of the electric field have been well developed. In this paper, we present a decomposition method of MT impedance tensors over a regional 1D conductivity anisotropic Earth, in which the galvanic distortion of both the electric and the associated magnetic fields are taken into account. An eigenparameter analysis is introduced to evaluate the intrinsic indeterminacy of magnetic distortion parameters. Regional anisotropic responses and EM distortion parameters are resolved by using a modified BFGS quasi-Newton algorithm combined with phase tensor analysis and the trust region method. In the presence of near-surface anisotropic inhomogeneities, synthetic 2D data show an accentuated magnetic galvanic effect in the response tensors especially in the diagonal components probably due to the infinite extension in the strike direction. However, the magnetic galvanic distortion is not significant in synthetic 3D models. The decomposition scheme is also applied to the analysis of the BC87 dataset collected in southeastern British Columbia to investigate both the electric and magnetic field galvanic distortion.

Can Radiologists Replace Digital 2D Mammography with Synthetic 2D Mammography in Breast Cancer Screening and Diagnosis, or Are Both Still Needed?

Background/Objectives: Digital mammography (DM) has long been the standard for breast cancer screening, while digital breast tomosynthesis (DBT) offers an advanced 3D imaging modality capable of generating 2D Synthetic Mammography (SM) images. Despite SM’s potential to reduce radiation exposure, many clinics favor DM, with DBT and SM, due to its perceived diagnostic reliability. This study investigates whether radiologists can replace DM with SM in breast cancer screening and diagnosis or if both modalities are necessary. Methods: We retrospectively analyzed DM and SM images from 375 women aged 40–65 who underwent DM with DBT at King Khaled University Hospital from 2020–2022. Three radiologists evaluated the images using ACR BI-RADS, assessing diagnostic accuracy via the area under the receiver operating characteristic (ROC) curve (AUC). The agreement in cancer conspicuity, breast density, size, and calcifications were measured using weighted kappa (κ). Results: Among 57 confirmed cancer cases and 290 cancer-free cases, DM demonstrated higher sensitivity (82.5% vs. 78.9%) and diagnostic accuracy (AUC 0.800 vs. 0.783, p < 0.05) compared to SM. However, SM detected more suspicious calcifications in cancer cases (75.6% vs. 51.2%, p < 0.05). Agreement was fair for conspicuity (κ = 0.288) and calcifications (κ = 0.409), moderate for density (κ = 0.591), and poor for size (κ = 0.254). Conclusions: while SM demonstrates enhanced effectiveness in detecting microcalcifications, DM still proves superior in overall diagnostic accuracy and image clarity. Therefore, although SM offers certain advantages, it remains slightly inferior to DM and cannot yet replace DM in breast cancer screening.

In Vitro Assessment of Thermo-Responsive Scaffold as a 3D Synthetic Matrix for CAR-T Potency Testing Against Glioblastoma Spheroids.

Chimeric antigen receptor (CAR) T cell immunotherapy has demonstrated exceptional efficacy against hematological malignancies, but notably less against solid tumors. To overcome this limitation, it is critical to investigate antitumor CAR-T cell potency in synthetic 3D microenvironments that can simulate the physical barriers presented by solid tumors. The overall goal of this study was the preliminary assessment of a synthetic thermo-responsive material as a substrate for invitro co-cultures of anti-disialoganglioside (GD2) CAR-T cells and patient-derived glioblastoma (GBM) spheroids. Independent co-culture experiments demonstrated that the encapsulation process did not adversely affect the cell cycle progression of glioma stem cells (GSCs) or CAR-T cells. GSC spheroids grew over time within the terpolymer scaffold, when seeded in the same ratio as the suspension control. Co-cultures of CAR-T cells in suspension with hydrogel-encapsulated GSC spheroids demonstrated that CAR-T cells could migrate through the hydrogel and target the encapsulated GSC spheroids. CAR-T cells killed approximately 80% of encapsulated GSCs, while maintaining effective CD4:CD8 T cell ratios and secreting inflammatory cytokines after interacting with GD2-expressing GSCs. Importantly, the scaffolds also facilitated cell harvesting for downstream cellular analysis. This study demonstrated that a synthetic 3D terpolymer hydrogel can serve as an artificial scaffold to investigate cellular immunotherapeutic potency against solid tumors.

Use of Deep-Learning-Accelerated Gradient Approximation for Reservoir Geological Parameter Estimation

The estimation of space-varying geological parameters is often not computationally affordable for high-dimensional subsurface reservoir modeling systems. The adjoint method is generally regarded as an efficient approach for obtaining analytical gradient and, thus, proceeding with the gradient-based iteration algorithm; however, the infeasible memory requirement and computational demands strictly prohibit its generic implementation, especially for high-dimensional problems. The autoregressive neural network (aNN) model, as a nonlinear surrogate approximation, has gradually received increasing popularity due to significant reduction of computational cost, but one prominent limitation is that the generic application of aNN to large-scale reservoir models inevitably poses challenges in the training procedure, which remains unresolved. To address this issue, model-order reduction could be a promising strategy, which enables us to train the neural network in a very efficient manner. A very popular projection-based linear reduction method, i.e., propel orthogonal decomposition (POD), is adopted to achieve dimensionality reduction. This paper presents an architecture of a projection-based autoregressive neural network that efficiently derives an easy-to-use adjoint model by the use of an auto-differentiation module inside the popular deep learning frameworks. This hybrid neural network proxy, referred to as POD-aNN, is capable of speeding up derivation of reduced-order adjoint models. The performance of POD-aNN is validated through a synthetic 2D subsurface transport model. The use of POD-aNN significantly reduces the computation cost while the accuracy remains. In addition, our proposed POD-aNN can easily obtain multiple posterior realizations for uncertainty evaluation. The developed POD-aNN emulator is a data-driven approach for reduced-order modeling of nonlinear dynamic systems and, thus, should be a very efficient modeling tool to address many engineering applications related to intensive simulation-based optimization.

A computational study of the effects of graphene additions on electrical properties of polycrystalline copper

The addition of graphene has recently shown promise as a route for the significant improvement of the bulk electrical properties of metallic materials. We explore the effects these additions have on the net electrical conductivity of fabricated copper-graphene (Cu-Gr) nanocomposites as a function of grain structure and grain boundary properties. Synthetic 3D microstructures were generated to represent polycrystalline copper with different average grain diameters and twinned grain boundary fractions. Then, the Poisson equation of electrical transport was solved using a finite difference method in order to predict the net electrical conductivity of each microstructure. In this context, the potential effect of graphene on the conductivity of the composite was evaluated as a function of the number of affected grain boundaries. The results of these calculations indicate that 1.) as supported by literature, net electrical conductivity decreases with decreasing grain size, 2.) the presence of twinned grain boundaries results in smaller loss of conductivity than would otherwise be expected, and 3.) the presence of graphene on the grain boundaries can be expected to lead to improvements in net electrical conductivity. However, we also find that 4.) when the Cu grain structure becomes sufficiently refined, the addition of graphene could conceivably result in significant improvements in electrical conductivity over and above coarse-grained Cu. It is estimated from our calculations that, assuming microstructures with average grain sizes between 100 nm and 100 μm and graphene conductivity 1000 to 10,000 that of a typical Cu grain boundary, an improvement in electrical conductivity of approximately 17 % over that of bulk Cu may be attainable. Therefore, by performing this study we suggest a possible route for the improvement of Cu electrical properties through the addition of graphene.

Diagnostic performance of tomosynthesis plus synthetic mammography versus full-field digital mammography with or without tomosynthesis in breast cancer screening: A systematic review and meta-analysis.

Digital breast tomosynthesis (DBT) with full-field digital mammography (FFDM) exposes women to a higher radiation dose. A synthetic 2D mammogram (S2D) is a two-dimensional image constructed from DBT. We aim to evaluate the S2D performance when used alone or combined with DBT compared to FFDM alone or with DBT. Studies were included if they recruited screening participants and reported on S2D performance. Studies were excluded if they included symptomatic patients, imaging was for diagnostic purposes, or if participants had a breast cancer history. Meta-analyses for cancer detection rates (CDR) and Specificities were conducted where available. Differences in the performance of imaging modalities were calculated within individual studies, and these were pooled by meta-analysis. Out of 3241 records identified, 17 studies were included in the review and 13 in the meta-analysis. The estimated combined difference in CDRs per thousand among individual studies that reported on DBT plus S2D vs. FFDM and those reporting on DBT plus S2D versus DBT plus FFDM was 2.03 (95% CI 0.81-3.25) and - 0.15 (95% CI -1.17 to 0.86), respectively. The estimated difference in percent specificities was 1.13 (95% CI -0.06 to 2.31) in studies comparing DBT plus S2D and FFDM. In studies comparing DBT plus S2D and DBT plus FFDM, the estimated difference in specificities was 1.08 (95% CI 0.59-1.56). DBT plus S2D showed comparable accuracy to FFDM plus DPT and improved cancer detection to FFDM alone. Integrating S2D with DBT in breast cancer screening is safe and preserves performance.

Uncertainty quantification on small angle x-ray scattering measurement using Bayesian deep learning

Small angle x-ray scattering (SAXS) is a widely recognized solution for measuring complex nanostructures. With the increasing demand for accurately assessing structural characteristics and optimizing manufacturing processes, uncertainty quantification in SAXS inverse problems has become a critical issue. However, traditional methods face challenges such as slow computation speed and inaccurate estimation of multidimensional parameters. To overcome these issues, we propose an uncertainty quantification approach suitable for SAXS measurement that approximates the posterior using Bayesian deep learning. The effectiveness and reliability of our method are illustrated by assessing structural parameters of synthetic 2D Si grating samples. The uncertainty quantification takes only about 2.3 s, thousands of times faster than the conventional Markov Chain Monte Carlo (MCMC) methods. Also, our method has superior repeatability for parameter measurement compared to the MCMC approaches. It provides the potential of efficient and reliable SAXS measurement in increasingly intricate semiconductor manufacturing.

Updimensioning strategy derived from synthetic equiaxed grain structures for approximating 3D grain size distributions from 2D visualizations with 1D parameters

We generated synthetic equiaxed grain structures using computer graphics software to explore the relationship between various grain size determination methods and true three-dimensional (3D) grain diameters. Mirroring grain measurement techniques, the synthetic 3D grain structures are imaged as 2D micrographs which are measured to yield 1D grain size parameters. Synthetic grain structures provide data at a mass scale and permit exploration of both polished and fractured surface micrographs, revealing one-to-one correspondence between exposed 2D grain cross-sections and individual 3D grains. Analysis of this correspondence yielded a procedure to approximate 3D equiaxed grain size and volume distributions based on the mode of the 2D fractograph grain size distribution. The 3D approximation procedure is shown to be less susceptible to different imaging conditions that affect small, undiscernible grains compared to the standard planimetric and linear intercept methods, which by design also tend to underestimate the 3D grain diameter. The procedure requires larger sample sizes to lower variance and a deeper analysis which could become more practical with machine learning (ML) models for grain boundary segmentation, which synthetic grain structures can help train. This work lays the foundation for analyzing other grain distributions such as columnar and composite grains in similar depth.

Plastic deformation and damage modeling of AA7075 synthetic 3D microstructure created using generative AI

3D microstructures provide valuable insight into material behavior which is essential in elucidating microstructural phenomena, such as particle morphology and void damage, and consequent macroscopic material response. However, creating 3D microstructures is extremely laborious and expensive, requiring complex microstructural characterization and imaging techniques such as Focussed-Ion Beam based Scanning Electron Microscopy (FIB-SEM) or X-ray Computed Tomography (XCT). To this end, synthetic 3D microstructures were rapidly generated from orthogonal 2D images using SliceGAN, which proved a practical and cost-effective method. In this study, multiple synthetic microstructures of AA7075-O, a complex microstructure of various strengthening precipitates within a softer aluminum matrix, were post-processed, meshed, and modeled for different damage behavior in FEA using advanced constitutive material models. Subsequently, the synthetic and real microstructures were qualitatively and quantitatively analyzed for their elastoplastic deformation and ductile void damage responses.This study illustrates the viability of an integrated AI-FE methodology in studying microstructural micromechanics, demonstrating that synthetic microstructures exhibited a very similar stress-strain response, especially when using a free boundary condition, and comparable stress distribution and void damage, albeit with some discrepancies. Also, it emphasizes the influence of particle morphology on strength and damage, where highly irregular particles play a dual role in increasing strain hardening by restricting matrix flow at the cost of increased ductile damage induced by decohered particles. Lastly, the more advanced FE models, with multiple voiding mechanisms, reduced the discrepancy between real and synthetic microstructures compared to simpler models

Stochastic Modeling of Two-Phase Transport in Fractured Porous Media Under Geological Uncertainty Using an Improved Probabilistic Collocation Method

Summary Simulation of multiphase transport through fractured porous media is highly affected by the uncertainty in fracture distribution and matrix block size that arises from inherent heterogeneity. To quantify the effect of such uncertainties on displacement performance in porous media, the probabilistic collocation method (PCM) has been applied as a feasible and accurate approach. However, propagation of uncertainty during the simulation of unsteady-state transport through porous media could not be computed by this method or even by the direct-sampling Monte Carlo (MC) approach. Therefore, with this research, we implement a novel numerical modeling workflow that improves PCM on sparse grids and combines it with the Smolyak algorithm for selection of collocation points sets, Karhunen-Loeve (KL) decomposition, and polynomial chaos expansion (PCE) to compute the uncertainty propagation in oil-gas flow through fractured porous media in which gravity drainage force is enabled. The effect of uncertainty in the vertical dimension of matrix blocks, which are frequently an uncertain and history-matching parameter, on simulation results of randomly synthetic 3D fractured media is explored. The developed numerical model is innovatively coupled with solving governing deterministic partial differential equations (PDEs) to compute uncertainty propagation from the first timestep to the last timestep of the simulation. The uncertainty interval and aggregation of uncertainty in ultimate recovery are quantified, and statistical moments for simulation outputs are presented at each timestep. The results reveal that the model properly quantifies uncertainty and extremely reduces central processing unit (or CPU) time in comparison with MC simulation.

Development and validation of a realistic type III esophageal atresia simulator for the training of pediatric surgeons

BackgroundThe technical complexity and limited casuistry of neonatal surgical pathology limit the possibilities of developing the necessary technical competencies by specialists in training. Esophageal atresia constitutes the paradigm of this problem. The use of synthetic 3D models for training is a promising line of research, although the literature is limited.MethodsWe conceptualized, designed, and produced an anatomically realistic model for the open correction of type III oesophageal atresia. We validated it with two groups of participants (experts and non-experts) through face, construct, and content-validity questionnaires.ResultsThe model was validated by nine experts and nine non-experts. The mean procedure time for the experts and non-experts groups was 34.0 and 38.4 min, respectively. Two non-experts did not complete the procedure at the designed time (45 min). Regarding the face validity questionnaire, the mean rating of the model was 3.2 out of 4. Regarding the construct validity, we found statistically significant differences between groups for the equidistance between sutures, 100% correct in the expert group vs. 42.9% correct in the non-expert group (p = 0.02), and for the item “Confirms that tracheoesophageal fistula closure is watertight before continuing the procedure”, correctly assessed by 66.7% of the experts vs. by 11.1% of non-experts (p = 0.05). Concerning content validity, the mean score was 3.3 out of 4 for the experts and 3.4 out of 4 for the non-experts.ConclusionsThe present model is a cost-effective, simple-to-produce, and validated option for training open correction of type III esophageal atresia. However, future studies with larger sample sizes and blinded validators are needed before drawing definitive conclusions.

Minimum entropy constrained cooperative inversion of electrical resistivity, seismic and magnetic data

Geophysical methods are widely used to gather information about the subsurface as they are non-intrusive and comparably cheap. However, the solution to the geophysical inverse problem is inherently non-unique, which introduces considerable uncertainties. As a partial remedy to this problem, independently acquired geophysical data sets can be jointly inverted to reduce ambiguities in the resulting multi-physical subsurface images. A novel cooperative inversion approach with joint minimum entropy constraints is used to create more consistent multi-physical images with sharper boundaries with respect to the single-method inversions. Here, this approach is implemented in an open-source software and its applicability on electrical resistivity tomography (ERT), seismic refraction tomography (SRT), and magnetic data is investigated. A synthetic 2D ERT and SRT data study is used to demonstrate the approach and to investigate the influence of the governing parameters. The findings showcase the advantage of the joint minimum entropy (JME) stabilizer over separate, conventional smoothness-constrained inversions. The method is then used to analyze field data from Rockeskyller Kopf, Germany. 3D ERT and magnetic data are combined and the results confirm the expected volcanic diatreme structure with improved details. The multi-physical images of both methods are consistent in some regions, as similar boundaries are produced in the resulting models. Because of its sensitivity to hydrologic conditions in the subsurface, observations suggest that the ERT method senses different structures than the magnetic method. These structures in the ERT result do not seem to be enforced on the magnetic susceptibility distribution, showcasing the flexibility of the approach. Both investigations outline the importance of a suitable parameter and reference model selection for the performance of the approach and suggest careful parameter tests prior to the joint inversion. With proper settings, the JME inversion is a promising tool for geophysical imaging, however, this work also identifies some objectives for future studies and additional research to explore and optimize the method.

Benchmarking robustness of deep neural networks in semantic segmentation of fluorescence microscopy images

BackgroundFluorescence microscopy (FM) is an important and widely adopted biological imaging technique. Segmentation is often the first step in quantitative analysis of FM images. Deep neural networks (DNNs) have become the state-of-the-art tools for image segmentation. However, their performance on natural images may collapse under certain image corruptions or adversarial attacks. This poses real risks to their deployment in real-world applications. Although the robustness of DNN models in segmenting natural images has been studied extensively, their robustness in segmenting FM images remains poorly understoodResultsTo address this deficiency, we have developed an assay that benchmarks robustness of DNN segmentation models using datasets of realistic synthetic 2D FM images with precisely controlled corruptions or adversarial attacks. Using this assay, we have benchmarked robustness of ten representative models such as DeepLab and Vision Transformer. We find that models with good robustness on natural images may perform poorly on FM images. We also find new robustness properties of DNN models and new connections between their corruption robustness and adversarial robustness. To further assess the robustness of the selected models, we have also benchmarked them on real microscopy images of different modalities without using simulated degradation. The results are consistent with those obtained on the realistic synthetic images, confirming the fidelity and reliability of our image synthesis method as well as the effectiveness of our assay.ConclusionsBased on comprehensive benchmarking experiments, we have found distinct robustness properties of deep neural networks in semantic segmentation of FM images. Based on the findings, we have made specific recommendations on selection and design of robust models for FM image segmentation.

Boosting C2H6/C2H4 separation via the precise electrostatic modulation of synthetic 1D channel at atomic level

Boosting C2H6/C2H4 separation via the precise electrostatic modulation of synthetic 1D channel at atomic level

3D displacement measurement using a single-camera and mesh deformation neural network

Computer vision-based methods for civil structure’s vibration displacement measurement have emerged as useful tools in the recent years. These methods offer several benefits including non-contact measurements, cost-effectiveness, and the ability to capture full-field displacement. Yet, there remain certain challenges. Measuring vibration displacement in 3D typically requires multiple cameras, adding complexity to camera configurations. Moreover, existing methods relied heavily on physical markers or natural key points. Placing physical markers on structures is often impractical, and natural key points are difficult to detect on structures with few distinct features or during rapid movements. Contrary to previous approaches, this paper presents a novel technique that uses a monocular camera for 3D displacement measurements. This technique obviates the need for physical markers or the reliance on natural key points, representing a significant advancement. Central to the method is a deep neural network designed to predict 3D mesh deformation directly from a single image input, combined with an initial 3D cube mesh input. A synthetic 3D dataset is generated to train the neural network. In the testing phase for real structures, advanced video segmentation method is employed to remove the background in order to enhance the prediction accuracy. The practical efficacy of this methodology is validated in a laboratory through a series of experimental tests on beam structures, demonstrating reliable results and application potentials.

Increasing numerical stability of mountain valley glacier simulations: implementation and testing of free-surface stabilization in Elmer/Ice

Abstract. This paper concerns a numerical stabilization method for free-surface ice flow called the free-surface stabilization algorithm (FSSA). In the current study, the FSSA is implemented into the numerical ice-flow software Elmer/Ice and tested on synthetic two-dimensional (2D) glaciers, as well as on the real-world glacier of Midtre Lovénbreen, Svalbard. For the synthetic 2D cases it is found that the FSSA method increases the largest stable time-step size at least by a factor of 5 for the case of a gently sloping ice surface (∼ 3°) and by at least a factor of 2 for cases of moderately to steeply inclined surfaces (∼ 6° to 12°) on a fine mesh. Compared with other means of stabilization, the FSSA is the only one in this study that increases largest stable time-step sizes when used alone. Furthermore, the FSSA method increases the overall accuracy for all surface slopes. The largest stable time-step size is found to be smallest for the case of a low sloping surface, despite having overall smaller velocities. For an Arctic-type glacier, Midtre Lovénbreen, the FSSA method doubles the largest stable time-step size; however, the accuracy is in this case slightly lowered in the deeper parts of the glacier, while it increases near edges. The implication is that the non-FSSA method might be more accurate at predicting glacier thinning, while the FSSA method is more suitable for predicting future glacier extent. A possible application of the larger time-step sizes allowed for by the FSSA is for spin-up simulations, where relatively fast-changing climate data can be incorporated on short timescales, while the slow-changing velocity field is updated over larger timescales.

3DGEN: a framework for generating custom-made synthetic 3D datasets for civil structure health monitoring

The availability of high-quality datasets is increasingly critical in the field of computer vision-based civil structural health monitoring, where deep learning approaches have gained prominence. However, the lack of specialized datasets for such tasks poses a significant challenge for training a reliable model. To address this challenge, a framework, 3DGEN, is proposed to swiftly generate realistic synthetic 3D datasets which can be targeted for specific tasks. The framework is based on diverse 3D civil structural models, rendering them from various angles and providing depth information and camera parameters for training neural networks. By employing mathematical methods, such as analytical solutions and/or numerical simulations, deformation of civil engineering structures can be generated, ensuring a reliable representation of their real-world shapes and characteristics in the 3D datasets. For texture generation, a generative 3D texturing method enables users to specify desired textures using plain English sentences. Two successful experiments are conducted to (1) assess the efficiency of generating the 3D datasets using two distinct structures, (2) train a monocular depth estimation network to perform 3D surface reconstruction with the generated dataset. Notably, 3DGEN is not limited to 3D surface reconstruction; it can also be used for training neural networks for various other tasks. The code and dataset are available at: https://github.com/YANDA-SHAO/Beam-Dataset-SE

Seismic data denoising using the 3D curvelet transform method

One of the major difficulties in processing and interpreting seismic data is the contamination of seismic signals by noise from numerous sources. Conventional denoising methods are mostly used for processing 2D seismic data, but noise also exists in the 3D data space, resulting in poor results using conventional denoising methods. Consequently, here, for seismic data denoising, a multiscale and multidirectional 3D curvelet transform was adopted. Our study combined the core principle of the 3D curvelet approach with the threshold iteration method to denoise simulated and actual seismic data with varying signal-to-noise ratios, and the results were quantitatively compared with the processing outcomes of existing denoising methods. The effectiveness of our method is illustrated using both genuine 2D and 3D post-stack seismic data, and synthetic 2D sections with added white and colored noise. Finally, we demonstrate how to prepare the data for frequency-domain full-waveform inversion using curvelet denoising. Despite the complexity of the procedure used to create the training samples, testing results using synthetic and real seismic data demonstrate that this method has mastered the capacity to suppress Gaussian and super-Gaussian noise from various training samples.

Development of large-scale synthetic 3D point cloud datasets for vision-based bridge structural condition assessment

Visual recognition of 3D point cloud data of bridge inspection scenes is a key step in automating the visual inspection process, which is currently largely manual and inefficient. To alleviate the lack of large-scale annotated point cloud datasets for training such 3D visual recognition algorithms, this research investigates an approach for developing large-scale synthetic point cloud datasets. The proposed approach proceeds in four steps: (1) random generation of different types of bridges in computer graphics environments; (2) sampling of camera trajectories that represent data collection scenarios during bridge inspection; (3) 3D reconstruction using Structure from Motion (SfM) applied to rendered synthetic images; (4) automated annotation of the reconstructed point cloud using ground truth masks obtained with synthetic images. Besides, this research proposes to store point uncertainty information defined by the error between the ground truth depth and the depth calculated from the SfM results. Prior to training, thresholds can be applied to this uncertainty information to control the levels of outliers in the dataset. This research demonstrates the proposed approach by generating point cloud datasets for two data collection scenarios. The effectiveness of the generated datasets is investigated by training 3D semantic segmentation algorithms and evaluating the performance on real and synthetic point cloud data. The proposed approach for point cloud dataset generation will facilitate the development of generalizable and high level-of-detail 3D recognition algorithms toward autonomous bridge inspection.

Bayesian analysis of 1D [formula omitted]H-NMR spectra

Extracting spin system parameters from 1D high resolution 1H-NMR spectra can be an intricate task requiring sophisticate methods. With a few exceptions methods to perform such a total line shape analysis commonly rely on local optimization techniques which for increasing complexity of the underlying spin system tend to reveal local solutions. In this work we propose a full Bayesian modeling approach based on a quantum mechanical model of the spin system. The Bayesian formalism provides a global optimization strategy which allows to efficiently include prior knowledge about the spin system or to incorporate additional constraints concerning the parameters of interest. The proposed algorithm has been tested on synthetic and real 1D 1H-NMR data for various spin systems with increasing complexity. The results show that the Bayesian algorithm provides accurate estimates even for complex spectra with many overlapping regions, and that it can cope with symmetry induced local minima. By providing an unbiased estimate of the model evidence the proposed algorithm furthermore offers a way to discriminate between different spin system candidates.