Synthesis Of Β-aminophosphonates Research Articles

Visible photocatalysis of novel oxime phosphonates: synthesis of β-aminophosphonates.

A novel type of oxime phosphonate was synthesized and used in the intermolecular cascade radical addition reaction of alkenes to access β-aminophosphonates via visible-light-driven N-centered iminyl radical-mediated and redox-neutral selective C-P single-bond cleavage in an active phosphorus radical route. The procedure is characterized by its ability to achieve the construction of Csp3-P and Csp3-N bonds without the requirement for oxidants and bases.

The first synthesis of β-amino phosphonates using cyclic sulfamidates

Cyclic sulfamidates (prepared from α-amino acids and β-amino alcohols) have been used for the first time for the synthesis of novel β-amino phosphonates (chiral and achiral) by treatment with dialkyl phosphites using sodium hydride. 2-Substituted and 1,2-disubtituted β-amino phosphonates have efficiently been prepared following this method. The products are formed in high yield (79–84%) within 8–12 h.

Synthesis of β-Aminophosphonates and Study of Their Acid-Base Properties and Phase Distribution in Water-Organic Solvent Systems

New and previously known β-aminoethylphosphonates were synthesized by addition of primary and secondary amines to vinylphosphonates, and their IR and NMR spectra were examined. Diethyl 2-diethylaminoethylphosphonate and diethyl 2-morpholinoethylphosphonate were found to be stronger bases than the corresponding aminomethylphosphonates, but all these are weaker bases than their precursors, nonphosphorylated amines. Distribution constants of β-aminophosphonates between water and some organic solvents were determined and compared with those of their α-amino homologs.

Synthesis of β‐Aminophosphonates and ‐Phosphinates

AbstractFor Abstract see ChemInform Abstract in Full Text.

Synthesis of β-Aminophosphonates and -Phosphinates

Synthesis of <i>β</i>-Aminophosphonates and -Phosphinates

Synthesis of β-Amino Phosphonates in One-Pot Procedure

: β-amino phosphonate derivatives are synthesized in one-pot procedure via reduction of β-enamino phosphonate intermediates with NaBH4/acetic acid or trifluoroacetic acid.